2MQSA

Transient collagen triple helix binding to a key metalloproteinase in invasion and development: spin labels to structure
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
196
structure length
196
Chain Sequence
PNICDGNFDTVAMLRGEMFVFKERWFWRVRNNQVMDGYPMPIGQFWRGLPASINTAYERKDGKFVFFKGDKHWVFDEASLEPGYPKHIKELGRGLPTDKIDAALFWMPNGKTYFFRGNKYYRFNEELRAVDSEYPKNIKVWEGIPESPRGSFMGSDEVFTYFYKGNKYWKFNNQKLKVEPGYPKSALRDWMGCPSG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hydrolase
molecule keywords Matrix metalloproteinase-14
publication title Transient collagen triple helix binding to a key metalloproteinase in invasion and development.
pubmed doi rcsb
source organism Homo sapiens
total genus 47
structure length 196
sequence length 196
ec nomenclature ec 3.4.24.80: Membrane-type matrix metalloproteinase-1.
pdb deposition date 2014-06-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00045 Hemopexin Hemopexin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.110.10.10 Mainly Beta 4 Propeller Hemopexin Hemopexin-like domain 2mqsA00
4AUOA 1SU3A 4FU4A 2JXYA 1GXDA 1RTGA 1HXNA 3C7XA 4LL2A 3OYOA 1ITVA 1CK7A 3V6NA 1GENA 4HSDA 1FBLA 3BA0A 3S18A 2MQSA 1PEXA 3LP9A 4FVLA 2CLTA 4RT6B 4G0DA 4YEHA 4OEIA 1QHUA 1QJSA
chains in the Genus database with same CATH superfamily
4AUOA 1SU3A 4FU4A 2JXYA 1GXDA 1RTGA 1HXNA 3C7XA 4LL2A 3OYOA 1ITVA 1CK7A 3V6NA 1GENA 4HSDA 1FBLA 3BA0A 3S18A 2MQSA 1PEXA 3LP9A 4FVLA 2CLTA 4RT6B 4G0DA 4YEHA 4OEIA 1QHUA 1QJSA
chains in the Genus database with same CATH topology
4AUOA 1SU3A 4FU4A 2JXYA 1GXDA 1RTGA 1HXNA 3C7XA 4LL2A 3OYOA 1ITVA 1CK7A 3V6NA 1GENA 4HSDA 1FBLA 3BA0A 3S18A 2MQSA 1PEXA 3LP9A 4FVLA 2CLTA 4RT6B 4G0DA 4YEHA 4OEIA 1QHUA 1QJSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4AUO A;  1SU3 A;  4FU4 A;  2JXY A;  1GXD A;  1RTG A;  1HXN A;  3C7X A;  4LL2 A;  3OYO A;  1ITV A;  1CK7 A;  3V6N A;  1GEN A;  4HSD A;  1FBL A;  3BA0 A;  3S18 A;  2MQS A;  1PEX A;  3LP9 A;  4FVL A;  2CLT A;  4RT6 B;  4G0D A;  4YEH A;  4OEI A;  1QHU A;  1QJS A; 
#chains in the Genus database with same CATH topology
 4AUO A;  1SU3 A;  4FU4 A;  2JXY A;  1GXD A;  1RTG A;  1HXN A;  3C7X A;  4LL2 A;  3OYO A;  1ITV A;  1CK7 A;  3V6N A;  1GEN A;  4HSD A;  1FBL A;  3BA0 A;  3S18 A;  2MQS A;  1PEX A;  3LP9 A;  4FVL A;  2CLT A;  4RT6 B;  4G0D A;  4YEH A;  4OEI A;  1QHU A;  1QJS A; 
#chains in the Genus database with same CATH homology
 4AUO A;  1SU3 A;  4FU4 A;  2JXY A;  1GXD A;  1RTG A;  1HXN A;  3C7X A;  4LL2 A;  3OYO A;  1ITV A;  1CK7 A;  3V6N A;  1GEN A;  4HSD A;  1FBL A;  3BA0 A;  3S18 A;  2MQS A;  1PEX A;  3LP9 A;  4FVL A;  2CLT A;  4RT6 B;  4G0D A;  4YEH A;  4OEI A;  1QHU A;  1QJS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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