3OWVA

Structural insights into catalytic and substrate binding mechanisms of the strategic enda nuclease from streptococcus pneumoniae
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
229
structure length
218
Chain Sequence
SEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYSWTPPGWHQVKNLKGSYTHAVDRGALLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords DNA-entry nuclease
publication title Structural insights into catalytic and substrate binding mechanisms of the strategic EndA nuclease from Streptococcus pneumoniae.
pubmed doi rcsb
source organism Streptococcus pneumoniae
total genus 59
structure length 218
sequence length 229
chains with identical sequence B
ec nomenclature ec 3.1.30.-:
pdb deposition date 2010-09-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01223 Endonuclease_NS DNA/RNA non-specific endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.570.10 Alpha Beta 3-Layer(aba) Sandwich Extracellular Endonuclease; Chain A Extracellular Endonuclease, subunit A 3owvA00
3S5BA 2XGRA 5HRTA 4QGOA 3NKQA 3NKOA 3NKMA 1QAEA 1SMNA 3NKRA 1QL0A 4GTZA 4QH0A 4GTYA 3NKNA 3WAVA 4ZG9A 3NKPA 5KXAA 5DLWA 4GTWA 2XH3A 5LIAA 5L0EA 2XR9A 2XRGA 3ISMA 4B56A 5GKPA 3OWVA 3WAWA 5DLVA 3WAXA 5IJSA 1ZM8A 4ZGAA 4E3YA 4ZG7A 5GKCA 4GTXA 3WAYA 4A1NA 5L0BA 1G8TA 5L0KA 4ZG6A 2O3BA 5INHA 4QN0A 5DLTA 5IJQA 5LQQA
chains in the Genus database with same CATH superfamily
3S5BA 2XGRA 5HRTA 4QGOA 3NKQA 3NKOA 3NKMA 1QAEA 1SMNA 3NKRA 1QL0A 4GTZA 4QH0A 4GTYA 3NKNA 3WAVA 4ZG9A 3NKPA 5KXAA 5DLWA 4GTWA 2XH3A 5LIAA 5L0EA 2XR9A 2XRGA 3ISMA 4B56A 5GKPA 3OWVA 3WAWA 5DLVA 3WAXA 5IJSA 1ZM8A 4ZGAA 4E3YA 4ZG7A 5GKCA 4GTXA 3WAYA 4A1NA 5L0BA 1G8TA 5L0KA 4ZG6A 2O3BA 5INHA 4QN0A 5DLTA 5IJQA 5LQQA
chains in the Genus database with same CATH topology
3S5BA 2XGRA 5HRTA 4QGOA 3NKQA 3NKOA 3NKMA 1QAEA 1SMNA 3NKRA 1QL0A 4GTZA 4QH0A 4GTYA 3NKNA 3WAVA 4ZG9A 3NKPA 5KXAA 5DLWA 4GTWA 2XH3A 5LIAA 5L0EA 2XR9A 2XRGA 3ISMA 4B56A 5GKPA 3OWVA 3WAWA 5DLVA 3WAXA 5IJSA 1ZM8A 4ZGAA 4E3YA 4ZG7A 5GKCA 4GTXA 3WAYA 4A1NA 5L0BA 1G8TA 5L0KA 4ZG6A 2O3BA 5INHA 4QN0A 5DLTA 5IJQA 5LQQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3S5B A;  2XGR A;  5HRT A;  4QGO A;  3NKQ A;  3NKO A;  3NKM A;  1QAE A;  1SMN A;  3NKR A;  1QL0 A;  4GTZ A;  4QH0 A;  4GTY A;  3NKN A;  3WAV A;  4ZG9 A;  3NKP A;  5KXA A;  5DLW A;  4GTW A;  2XH3 A;  5LIA A;  5L0E A;  2XR9 A;  2XRG A;  3ISM A;  4B56 A;  5GKP A;  3OWV A;  3WAW A;  5DLV A;  3WAX A;  5IJS A;  1ZM8 A;  4ZGA A;  4E3Y A;  4ZG7 A;  5GKC A;  4GTX A;  3WAY A;  4A1N A;  5L0B A;  1G8T A;  5L0K A;  4ZG6 A;  2O3B A;  5INH A;  4QN0 A;  5DLT A;  5IJQ A;  5LQQ A; 
#chains in the Genus database with same CATH topology
 3S5B A;  2XGR A;  5HRT A;  4QGO A;  3NKQ A;  3NKO A;  3NKM A;  1QAE A;  1SMN A;  3NKR A;  1QL0 A;  4GTZ A;  4QH0 A;  4GTY A;  3NKN A;  3WAV A;  4ZG9 A;  3NKP A;  5KXA A;  5DLW A;  4GTW A;  2XH3 A;  5LIA A;  5L0E A;  2XR9 A;  2XRG A;  3ISM A;  4B56 A;  5GKP A;  3OWV A;  3WAW A;  5DLV A;  3WAX A;  5IJS A;  1ZM8 A;  4ZGA A;  4E3Y A;  4ZG7 A;  5GKC A;  4GTX A;  3WAY A;  4A1N A;  5L0B A;  1G8T A;  5L0K A;  4ZG6 A;  2O3B A;  5INH A;  4QN0 A;  5DLT A;  5IJQ A;  5LQQ A; 
#chains in the Genus database with same CATH homology
 3S5B A;  2XGR A;  5HRT A;  4QGO A;  3NKQ A;  3NKO A;  3NKM A;  1QAE A;  1SMN A;  3NKR A;  1QL0 A;  4GTZ A;  4QH0 A;  4GTY A;  3NKN A;  3WAV A;  4ZG9 A;  3NKP A;  5KXA A;  5DLW A;  4GTW A;  2XH3 A;  5LIA A;  5L0E A;  2XR9 A;  2XRG A;  3ISM A;  4B56 A;  5GKP A;  3OWV A;  3WAW A;  5DLV A;  3WAX A;  5IJS A;  1ZM8 A;  4ZGA A;  4E3Y A;  4ZG7 A;  5GKC A;  4GTX A;  3WAY A;  4A1N A;  5L0B A;  1G8T A;  5L0K A;  4ZG6 A;  2O3B A;  5INH A;  4QN0 A;  5DLT A;  5IJQ A;  5LQQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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