3YGSP

Apaf-1 card in complex with prodomain of procaspase-9
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
97
structure length
97
Chain Sequence
SMDEADRRLLRRCRLRLVEELQVDQLWDVLLSRELFRPHMIEDIQRAGSGSRRDQARQLIIDLETRGSQALPLFISCLEDTGQDMLASFLRTNRQAG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Apoptosis
molecule keywords APOPTOTIC PROTEASE ACTIVATING FACTOR 1
publication title Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1.
pubmed doi rcsb
source organism Homo sapiens
total genus 38
structure length 97
sequence length 97
ec nomenclature ec 3.4.22.62: Caspase-9.
pdb deposition date 1999-05-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
P PF00619 CARD Caspase recruitment domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.533.10 Mainly Alpha Orthogonal Bundle Death Domain, Fas Death Domain, Fas 3ygsP00
3YGSP 4F44A 1DGNA 1N3KA 4P4HA 4N1KA 3LQRA 3MOPG 3QF2A 2OF5H 1PN5A 4O9LA 4UZ0A 2N1FA 4N1LA 4NQKA 2LWEA 2DBGA 4P4HI 2MPCA 1ICHA 2LS7A 2L9MA 3MOPK 2KM6A 2BBZA 2OF5A 2DO9A 2YVIA 3EZQB 2G7RA 1WH4A 1A1WA 1D2ZB 1E41A 4M9ZA 2NAQA 3MOPA 2NZ7A 1NGRA 4FH0A 4ZBWA 1YGOA 2P1HA 4LWDA 2DBDA 1E3YA 2NSNA 2GF5A 3T6PA 2N83A 3LQQA 1WMGA 4IZ7B 4RHWA 2DBFA 1DDFA 2MS8A 2A9IA 1FADA 3J6JA 4JQWA 4EWIA 2L6AA 4O6XA 2O71A 2MN4A 2M5VA 4O7QA 4I16A 1A1ZA 4E9MA 4JUPA 1D2ZA 3YGSC 2IB1A 4M9XA 4DWNA 4A2QA 1CWWA 2VGQA 4D8OA 4QOBA 4O9FA 2N80A 2DBHA 4F42A 1WXPA 2HM2Q 2MB9A 2YQFA 2N97A 2A5YB 4M9SA 2MS7A 4A2WA 3KATA 2N00A 2B1WA 2BBRA 4RHWE 2YGSA 2KN6A 1Z6TA 2D96A 4IZ5E 2LWDA 4N1JA 3EZQA 1C15A 3CL3A 1CY5A 4IZAB 1UCPA 3J63A 2F1SA 3CRDA 2YU0A 2N7ZA
chains in the Genus database with same CATH superfamily
3YGSP 4F44A 1DGNA 1N3KA 4P4HA 2MJMA 4N1KA 3LQRA 3MOPG 3QF2A 2OF5H 1PN5A 4O9LA 4UZ0A 2N1FA 4N1LA 4NQKA 2LWEA 2DBGA 4P4HI 2MPCA 1ICHA 2LS7A 2L9MA 3MOPK 2KM6A 2BBZA 2OF5A 2DO9A 2YVIA 3EZQB 2G7RA 1WH4A 1A1WA 1D2ZB 1E41A 4M9ZA 2NAQA 3MOPA 2NZ7A 1NGRA 4FH0A 4ZBWA 1YGOA 2P1HA 4LWDA 2DBDA 1E3YA 2NSNA 2GF5A 3T6PA 2N83A 3LQQA 1WMGA 4IZ7B 4RHWA 2DBFA 1DDFA 2MS8A 2A9IA 1FADA 3J6JA 4JQWA 4EWIA 2L6AA 4O6XA 2XV9A 2O71A 2MN4A 2M5VA 4O7QA 4I16A 1A1ZA 4E9MA 4JUPA 1D2ZA 3YGSC 2IB1A 4M9XA 4DWNA 4A2QA 1CWWA 2VGQA 4D8OA 4QOBA 4O9FA 2N80A 2DBHA 4F42A 1WXPA 2HM2Q 2MB9A 2YQFA 2N97A 2A5YB 4M9SA 2MS7A 4A2WA 3KATA 2N00A 2B1WA 2BBRA 4RHWE 2YGSA 2KN6A 1Z6TA 2D96A 4IZ5E 2LWDA 4N1JA 3EZQA 1C15A 3CL3A 1CY5A 4IZAB 1UCPA 3J63A 2F1SA 3CRDA 2YU0A 2N7ZA
chains in the Genus database with same CATH topology
3YGSP 4F44A 1DGNA 1N3KA 4P4HA 2MJMA 4N1KA 3LQRA 3MOPG 3QF2A 2OF5H 1PN5A 4O9LA 4UZ0A 2N1FA 4N1LA 4NQKA 2LWEA 2DBGA 4P4HI 2MPCA 1ICHA 2LS7A 2L9MA 3MOPK 2KM6A 2BBZA 2OF5A 2DO9A 2YVIA 3EZQB 2G7RA 1WH4A 1A1WA 1D2ZB 1E41A 4M9ZA 2NAQA 3MOPA 2NZ7A 1NGRA 4FH0A 4ZBWA 1YGOA 2P1HA 4LWDA 2DBDA 1E3YA 2NSNA 2GF5A 3T6PA 2N83A 3LQQA 1WMGA 4IZ7B 4RHWA 2DBFA 1DDFA 2MS8A 2A9IA 1FADA 3J6JA 4JQWA 4EWIA 2L6AA 4O6XA 2XV9A 2O71A 2MN4A 2M5VA 4O7QA 4I16A 1A1ZA 4E9MA 4JUPA 1D2ZA 3YGSC 2IB1A 4M9XA 4DWNA 4A2QA 1CWWA 2VGQA 4D8OA 4QOBA 4O9FA 2N80A 2DBHA 4F42A 1WXPA 2HM2Q 2MB9A 2YQFA 2N97A 2A5YB 4M9SA 2MS7A 4A2WA 3KATA 2N00A 2B1WA 2BBRA 4RHWE 2YGSA 2KN6A 1Z6TA 2D96A 4IZ5E 2LWDA 4N1JA 3EZQA 1C15A 3CL3A 1CY5A 4IZAB 1UCPA 3J63A 2F1SA 3CRDA 2YU0A 2N7ZA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3YGS P;  4F44 A;  1DGN A;  1N3K A;  4P4H A;  4N1K A;  3LQR A;  3MOP G;  3QF2 A;  2OF5 H;  1PN5 A;  4O9L A;  4UZ0 A;  2N1F A;  4N1L A;  4NQK A;  2LWE A;  2DBG A;  4P4H I;  2MPC A;  1ICH A;  2LS7 A;  2L9M A;  3MOP K;  2KM6 A;  2BBZ A;  2OF5 A;  2DO9 A;  2YVI A;  3EZQ B;  2G7R A;  1WH4 A;  1A1W A;  1D2Z B;  1E41 A;  4M9Z A;  2NAQ A;  3MOP A;  2NZ7 A;  1NGR A;  4FH0 A;  4ZBW A;  1YGO A;  2P1H A;  4LWD A;  2DBD A;  1E3Y A;  2NSN A;  2GF5 A;  3T6P A;  2N83 A;  3LQQ A;  1WMG A;  4IZ7 B;  4RHW A;  2DBF A;  1DDF A;  2MS8 A;  2A9I A;  1FAD A;  3J6J A;  4JQW A;  4EWI A;  2L6A A;  4O6X A;  2O71 A;  2MN4 A;  2M5V A;  4O7Q A;  4I16 A;  1A1Z A;  4E9M A;  4JUP A;  1D2Z A;  3YGS C;  2IB1 A;  4M9X A;  4DWN A;  4A2Q A;  1CWW A;  2VGQ A;  4D8O A;  4QOB A;  4O9F A;  2N80 A;  2DBH A;  4F42 A;  1WXP A;  2HM2 Q;  2MB9 A;  2YQF A;  2N97 A;  2A5Y B;  4M9S A;  2MS7 A;  4A2W A;  3KAT A;  2N00 A;  2B1W A;  2BBR A;  4RHW E;  2YGS A;  2KN6 A;  1Z6T A;  2D96 A;  4IZ5 E;  2LWD A;  4N1J A;  3EZQ A;  1C15 A;  3CL3 A;  1CY5 A;  4IZA B;  1UCP A;  3J63 A;  2F1S A;  3CRD A;  2YU0 A;  2N7Z A; 
#chains in the Genus database with same CATH topology
 3YGS P;  4F44 A;  1DGN A;  1N3K A;  4P4H A;  2MJM A;  4N1K A;  3LQR A;  3MOP G;  3QF2 A;  2OF5 H;  1PN5 A;  4O9L A;  4UZ0 A;  2N1F A;  4N1L A;  4NQK A;  2LWE A;  2DBG A;  4P4H I;  2MPC A;  1ICH A;  2LS7 A;  2L9M A;  3MOP K;  2KM6 A;  2BBZ A;  2OF5 A;  2DO9 A;  2YVI A;  3EZQ B;  2G7R A;  1WH4 A;  1A1W A;  1D2Z B;  1E41 A;  4M9Z A;  2NAQ A;  3MOP A;  2NZ7 A;  1NGR A;  4FH0 A;  4ZBW A;  1YGO A;  2P1H A;  4LWD A;  2DBD A;  1E3Y A;  2NSN A;  2GF5 A;  3T6P A;  2N83 A;  3LQQ A;  1WMG A;  4IZ7 B;  4RHW A;  2DBF A;  1DDF A;  2MS8 A;  2A9I A;  1FAD A;  3J6J A;  4JQW A;  4EWI A;  2L6A A;  4O6X A;  2XV9 A;  2O71 A;  2MN4 A;  2M5V A;  4O7Q A;  4I16 A;  1A1Z A;  4E9M A;  4JUP A;  1D2Z A;  3YGS C;  2IB1 A;  4M9X A;  4DWN A;  4A2Q A;  1CWW A;  2VGQ A;  4D8O A;  4QOB A;  4O9F A;  2N80 A;  2DBH A;  4F42 A;  1WXP A;  2HM2 Q;  2MB9 A;  2YQF A;  2N97 A;  2A5Y B;  4M9S A;  2MS7 A;  4A2W A;  3KAT A;  2N00 A;  2B1W A;  2BBR A;  4RHW E;  2YGS A;  2KN6 A;  1Z6T A;  2D96 A;  4IZ5 E;  2LWD A;  4N1J A;  3EZQ A;  1C15 A;  3CL3 A;  1CY5 A;  4IZA B;  1UCP A;  3J63 A;  2F1S A;  3CRD A;  2YU0 A;  2N7Z A; 
#chains in the Genus database with same CATH homology
 3YGS P;  4F44 A;  1DGN A;  1N3K A;  4P4H A;  2MJM A;  4N1K A;  3LQR A;  3MOP G;  3QF2 A;  2OF5 H;  1PN5 A;  4O9L A;  4UZ0 A;  2N1F A;  4N1L A;  4NQK A;  2LWE A;  2DBG A;  4P4H I;  2MPC A;  1ICH A;  2LS7 A;  2L9M A;  3MOP K;  2KM6 A;  2BBZ A;  2OF5 A;  2DO9 A;  2YVI A;  3EZQ B;  2G7R A;  1WH4 A;  1A1W A;  1D2Z B;  1E41 A;  4M9Z A;  2NAQ A;  3MOP A;  2NZ7 A;  1NGR A;  4FH0 A;  4ZBW A;  1YGO A;  2P1H A;  4LWD A;  2DBD A;  1E3Y A;  2NSN A;  2GF5 A;  3T6P A;  2N83 A;  3LQQ A;  1WMG A;  4IZ7 B;  4RHW A;  2DBF A;  1DDF A;  2MS8 A;  2A9I A;  1FAD A;  3J6J A;  4JQW A;  4EWI A;  2L6A A;  4O6X A;  2XV9 A;  2O71 A;  2MN4 A;  2M5V A;  4O7Q A;  4I16 A;  1A1Z A;  4E9M A;  4JUP A;  1D2Z A;  3YGS C;  2IB1 A;  4M9X A;  4DWN A;  4A2Q A;  1CWW A;  2VGQ A;  4D8O A;  4QOB A;  4O9F A;  2N80 A;  2DBH A;  4F42 A;  1WXP A;  2HM2 Q;  2MB9 A;  2YQF A;  2N97 A;  2A5Y B;  4M9S A;  2MS7 A;  4A2W A;  3KAT A;  2N00 A;  2B1W A;  2BBR A;  4RHW E;  2YGS A;  2KN6 A;  1Z6T A;  2D96 A;  4IZ5 E;  2LWD A;  4N1J A;  3EZQ A;  1C15 A;  3CL3 A;  1CY5 A;  4IZA B;  1UCP A;  3J63 A;  2F1S A;  3CRD A;  2YU0 A;  2N7Z A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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