3C7XA

Hemopexin-like domain of matrix metalloproteinase 14
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
196
structure length
196
Chain Sequence
PNICDGNFDTVAMLRGEMFVFKERWFWRVRNNQVMDGYPMPIGQFWRGLPASINTAYERKDGKFVFFKGDKHWVFDEASLEPGYPKHIKELGRGLPTDKIDAALFWMPNGKTYFFRGNKYYRFNEELRAVDSEYPKNIKVWEGIPESPRGSFMGSDEVFTYFYKGNKYWKFNNQKLKVEPGYPKSALRDWMGCPSG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hydrolase
molecule keywords Matrix metalloproteinase-14
publication title The dimer interface of the membrane type 1 matrix metalloproteinase hemopexin domain: crystal structure and biological functions
pubmed doi rcsb
source organism Homo sapiens
total genus 41
structure length 196
sequence length 196
ec nomenclature ec 3.4.24.80: Membrane-type matrix metalloproteinase-1.
pdb deposition date 2008-02-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00045 Hemopexin Hemopexin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.110.10.10 Mainly Beta 4 Propeller Hemopexin Hemopexin-like domain 3c7xA00
1ITVA 4LL2A 4YEHA 1QJSA 1GXDA 4FVLA 1CK7A 1FBLA 2MQSA 4HSDA 3OYOA 3LP9A 4G0DA 1PEXA 1RTGA 3S18A 4RT6B 3BA0A 3V6NA 1QHUA 1HXNA 3C7XA 4AUOA 4OEIA 4FU4A 1GENA 2CLTA 2JXYA 1SU3A
chains in the Genus database with same CATH superfamily
1ITVA 4LL2A 4YEHA 1QJSA 1GXDA 4FVLA 1CK7A 1FBLA 2MQSA 4HSDA 3OYOA 3LP9A 4G0DA 1PEXA 1RTGA 3S18A 4RT6B 3BA0A 3V6NA 1QHUA 1HXNA 3C7XA 4AUOA 4OEIA 4FU4A 1GENA 2CLTA 2JXYA 1SU3A
chains in the Genus database with same CATH topology
1ITVA 4LL2A 4YEHA 1QJSA 1GXDA 4FVLA 1CK7A 1FBLA 2MQSA 4HSDA 3OYOA 3LP9A 4G0DA 1PEXA 1RTGA 3S18A 4RT6B 3BA0A 3V6NA 1QHUA 1HXNA 3C7XA 4AUOA 4OEIA 4FU4A 1GENA 2CLTA 2JXYA 1SU3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ITV A;  4LL2 A;  4YEH A;  1QJS A;  1GXD A;  4FVL A;  1CK7 A;  1FBL A;  2MQS A;  4HSD A;  3OYO A;  3LP9 A;  4G0D A;  1PEX A;  1RTG A;  3S18 A;  4RT6 B;  3BA0 A;  3V6N A;  1QHU A;  1HXN A;  3C7X A;  4AUO A;  4OEI A;  4FU4 A;  1GEN A;  2CLT A;  2JXY A;  1SU3 A; 
#chains in the Genus database with same CATH topology
 1ITV A;  4LL2 A;  4YEH A;  1QJS A;  1GXD A;  4FVL A;  1CK7 A;  1FBL A;  2MQS A;  4HSD A;  3OYO A;  3LP9 A;  4G0D A;  1PEX A;  1RTG A;  3S18 A;  4RT6 B;  3BA0 A;  3V6N A;  1QHU A;  1HXN A;  3C7X A;  4AUO A;  4OEI A;  4FU4 A;  1GEN A;  2CLT A;  2JXY A;  1SU3 A; 
#chains in the Genus database with same CATH homology
 1ITV A;  4LL2 A;  4YEH A;  1QJS A;  1GXD A;  4FVL A;  1CK7 A;  1FBL A;  2MQS A;  4HSD A;  3OYO A;  3LP9 A;  4G0D A;  1PEX A;  1RTG A;  3S18 A;  4RT6 B;  3BA0 A;  3V6N A;  1QHU A;  1HXN A;  3C7X A;  4AUO A;  4OEI A;  4FU4 A;  1GEN A;  2CLT A;  2JXY A;  1SU3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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