3JWQA

Crystal structure of chimeric pde5/pde6 catalytic domain complexed with sildenafil
Total Genus 133
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
133
sequence length
324
structure length
324
Chain Sequence
ETRELQSLAAAVVPSAQTLKITDFSFSDFELSDLETALCTIRMFTDLNLVQNFQMKHEVLCRWILSVKKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQNKLTDLEILALLIAALSHDLDHRGVNNSYIQRSEHPLAQLYCHSIMEHHHFDQCLMILNSPGNQILSGLSIEEYKTTLKIIKQAILATDLALYIKRRGEFFELIRKNQFNLEDPHQKELFLAMLMTACDLSAITKPWPIQQRIAELVATEFWEQGDLERTVLQQQPIPMMDRNKRDELPKLQVGFIDFVCTQLYEALTHVSEDCFPLLDGCRKNRQKWQALAEQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis of phosphodiesterase 6 inhibition by the C-terminal region of the gamma-subunit
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords cGMP-specific 3',5'-cyclic phosphodiesterase catalytic domai
total genus 133
structure length 324
sequence length 324
chains with identical sequence B, C, D
ec nomenclature ec 3.1.4.35: 3',5'-cyclic-GMP phosphodiesterase.
pdb deposition date 2009-09-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00233 PDEase_I 3'5'-cyclic nucleotide phosphodiesterase
A PF00233 PDEase_I 3'5'-cyclic nucleotide phosphodiesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1300.10 Mainly Alpha Orthogonal Bundle Catalytic domain of cyclic nucleotide phosphodiesterase 4b2b 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain 3jwqA00
3JWRA 1XOTA 3TGGA 1TB5A 1Y2EA 1XMYA 1ZKLA 1SO2A 4LM3A 3SL3A 5EDHA 4JIBA 5DH4A 3SL8A 5EDIB 3WYMA 1MKDA 3DYNA 4MSHA 3SNLA 3WD9A 1XP0A 2H44A 3DYSA 2CHMA 2WEYA 1TB7A 1Y2CA 3IADA 3JWQA 3GWTA 3QPNA 4LLXA 5K9RA 4LLPA 3ECMA 4DDLA 3K4SA 1Z1LA 1PTWA 4LKQA 4QGEA 1TBBA 1T9SA 2OUUA 3N3ZA 3HQWA 3SHYA 1RO6A 3SNIA 4KP6A 4GH6A 1XMYB 1Q9MA 4D09A 4PHLA 3HDZA 5EDEA 3G58A 4MVHA 3DYQA 3QI4A 3G4LA 2FM5A 1Y2DA 3SL4A 4DFFA 1XM4A 3ITMA 4C1IA 3G4GA 4MRZA 2OURA 4AJDA 3ECNA 4MSCA 3G45A 1XM6A 4X0FA 4OEXA 1RKPA 3IBJA 1XLZA 2OUSA 2OVYA 5C2HA 3TVXA 3WS8A 2OUPA 2OUNA 3WYKA 4PM0A 5C28A 4OGBA 5EDEB 1XMUB 4HF4A 4AELA 4Y87A 3D3PA 2QYKA 1F0JA 2OUYA 3SN7A 5C1WA 1XOZA 1XM4B 4HEUA 3LXGA 5K1IA 4MSEA 3HC8A 5DH5A 3G4IA 3WI2A 3TGEA 1SOJA 4WZIA 4HTXA 1XMUA 4LLJA 1TAZA 2Y0JA 4AJMA 1T9RA 2HD1A 4IA0A 3LY2A 1XOSA 2YY2A 3DY8A 4LLKA 1XLXA 4FCBA 4AJGA 3K3HA 1Y2HA 4Y8CA 4Y86A 3WS9A 3QPPA 3G3NA 3V9BA 1UHOA 5EDGA 4ZO5A 3SL5A 2PW3A 1XONA 4MRWA 2H42A 1Y2BA 2H40A 5B4KA 4AJFA 1UDTA 3JSWA 4TPPA 4LM2A 3JSIA 1ZKNA 1UDUA 3BJCA 3FRGA 4MD6A 3O57A 4G2WA 2O8HA 3DYLA 3UUOA 1Y2KA 2R8QA 4E90A 3UI7A 4BBXA 3I8VA 5B25A 3QPOA 4W1OA 3WYLA 3SL6A 2QYLA 4MSNA 5AXPA 2OUVA 3HQYA 4WCUA 1XOQA 3O0JA 1XORA 4P0NA 4TPMA 1RORA 5K32A 3V94A 4G2YA 5EDGB 3B2RA 5C2EA 3W5EA 3HMVA 5C29A 4I9ZA 3V93A 4D08A 1OYNA 4G2JA 3ITUA 2OUQA 4YQHA 2FM0A 2QYNA 3KKTA 4MUWA 5B4LA 3SHZA 5C2AA 4WN1A 4G2LA 2QYMA 2OVVA 3IAKA 3G4KA 3HR1A 3O56A 4LM4A 3HQZA 4MYQA 4NPVA 4LM0A 4NPWA 4OEWA 4Y2BA 4HTZA 4XY2A 4MSAA 5I2RA 1RO9A 4PHWA 1XOMA 3K3EA 4MS0A 5AXQA 1XN0A 4FCDA 3SIEA 4YS7A 1TBFA 4P1RA 1Y2JA 5EDIA 4I15A 4NW7A 3QI3A 4LM1A
chains in the Genus database with same CATH superfamily
3JWRA 1XOTA 3TGGA 1TB5A 1Y2EA 1XMYA 1ZKLA 1SO2A 4LM3A 3SL3A 5EDHA 4JIBA 5DH4A 3SL8A 5EDIB 3WYMA 1MKDA 3DYNA 4MSHA 3SNLA 3WD9A 1XP0A 2H44A 3DYSA 2CHMA 2WEYA 1TB7A 1Y2CA 3IADA 3JWQA 3GWTA 3QPNA 4LLXA 5K9RA 4LLPA 3ECMA 4DDLA 3K4SA 1Z1LA 1PTWA 4LKQA 4QGEA 1TBBA 1T9SA 2OUUA 3N3ZA 3HQWA 3SHYA 1RO6A 3SNIA 4KP6A 4GH6A 1XMYB 1Q9MA 4D09A 4PHLA 3HDZA 5EDEA 3G58A 4MVHA 3DYQA 3QI4A 3G4LA 2FM5A 1Y2DA 3SL4A 4DFFA 1XM4A 3ITMA 4C1IA 3G4GA 4MRZA 2OURA 4AJDA 3ECNA 4MSCA 3G45A 1XM6A 4X0FA 4OEXA 1RKPA 3IBJA 1XLZA 2OUSA 2OVYA 5C2HA 3TVXA 3WS8A 2OUPA 2OUNA 3WYKA 4PM0A 5C28A 4OGBA 5EDEB 1XMUB 4HF4A 4AELA 4Y87A 3D3PA 2QYKA 1F0JA 2OUYA 3SN7A 5C1WA 1XOZA 1XM4B 4HEUA 3LXGA 5K1IA 4MSEA 3HC8A 5DH5A 3G4IA 3WI2A 3TGEA 1SOJA 4WZIA 4HTXA 1XMUA 4LLJA 1TAZA 2Y0JA 4AJMA 1T9RA 2HD1A 4IA0A 3LY2A 1XOSA 2YY2A 3DY8A 4LLKA 1XLXA 4FCBA 4AJGA 3K3HA 1Y2HA 4Y8CA 4Y86A 3WS9A 3QPPA 3G3NA 3V9BA 1UHOA 5EDGA 4ZO5A 3SL5A 2PW3A 1XONA 4MRWA 2H42A 1Y2BA 2H40A 5B4KA 4AJFA 1UDTA 3JSWA 4TPPA 4LM2A 3JSIA 1ZKNA 1UDUA 3BJCA 3FRGA 4MD6A 3O57A 4G2WA 2O8HA 3DYLA 3UUOA 1Y2KA 2R8QA 4E90A 3UI7A 4BBXA 3I8VA 5B25A 3QPOA 4W1OA 3WYLA 3SL6A 2QYLA 4MSNA 5AXPA 2OUVA 3HQYA 4WCUA 1XOQA 3O0JA 1XORA 4P0NA 4TPMA 1RORA 5K32A 3V94A 4G2YA 5EDGB 3B2RA 5C2EA 3W5EA 3HMVA 5C29A 4I9ZA 3V93A 4D08A 1OYNA 4G2JA 3ITUA 2OUQA 4YQHA 2FM0A 2QYNA 3KKTA 4MUWA 5B4LA 3SHZA 5C2AA 4WN1A 4G2LA 2QYMA 2OVVA 3IAKA 3G4KA 3HR1A 3O56A 4LM4A 3HQZA 4MYQA 4NPVA 4LM0A 4NPWA 4OEWA 4Y2BA 4HTZA 4XY2A 4MSAA 5I2RA 1RO9A 4PHWA 1XOMA 3K3EA 4MS0A 5AXQA 1XN0A 4FCDA 3SIEA 4YS7A 1TBFA 4P1RA 1Y2JA 5EDIA 4I15A 4NW7A 3QI3A 4LM1A
chains in the Genus database with same CATH topology
3JWRA 1XOTA 3TGGA 1TB5A 1Y2EA 1XMYA 1ZKLA 1SO2A 4LM3A 3SL3A 5EDHA 4JIBA 5DH4A 3SL8A 5EDIB 3WYMA 1MKDA 3DYNA 4MSHA 3SNLA 3WD9A 1XP0A 2H44A 3DYSA 2CHMA 2WEYA 1TB7A 1Y2CA 3IADA 3JWQA 3GWTA 3QPNA 4LLXA 5K9RA 4LLPA 3ECMA 4DDLA 3K4SA 1Z1LA 1PTWA 4LKQA 4QGEA 1TBBA 1T9SA 2OUUA 3N3ZA 3HQWA 3SHYA 1RO6A 3SNIA 4KP6A 4GH6A 1XMYB 1Q9MA 4D09A 4PHLA 3HDZA 5EDEA 3G58A 4MVHA 3DYQA 3QI4A 3G4LA 2FM5A 1Y2DA 3SL4A 4DFFA 1XM4A 3ITMA 4C1IA 3G4GA 4MRZA 2OURA 4AJDA 3ECNA 4MSCA 3G45A 1XM6A 4X0FA 4OEXA 1RKPA 3IBJA 1XLZA 2OUSA 2OVYA 5C2HA 3TVXA 3WS8A 2OUPA 2OUNA 3WYKA 4PM0A 5C28A 4OGBA 5EDEB 1XMUB 4HF4A 4AELA 4Y87A 3D3PA 2QYKA 1F0JA 2OUYA 3SN7A 5C1WA 1XOZA 1XM4B 4HEUA 3LXGA 5K1IA 4MSEA 3HC8A 5DH5A 3G4IA 3WI2A 3TGEA 1SOJA 4WZIA 4HTXA 1XMUA 4LLJA 1TAZA 2Y0JA 4AJMA 1T9RA 2HD1A 4IA0A 3LY2A 1XOSA 2YY2A 3DY8A 4LLKA 1XLXA 4FCBA 4AJGA 3K3HA 1Y2HA 4Y8CA 4Y86A 3WS9A 3QPPA 3G3NA 3V9BA 1UHOA 5EDGA 4ZO5A 3SL5A 2PW3A 1XONA 4MRWA 2H42A 1Y2BA 2H40A 5B4KA 4AJFA 1UDTA 3JSWA 4TPPA 4LM2A 3JSIA 1ZKNA 1UDUA 3BJCA 3FRGA 4MD6A 3O57A 4G2WA 2O8HA 3DYLA 3UUOA 1Y2KA 2R8QA 4E90A 3UI7A 4BBXA 3I8VA 5B25A 3QPOA 4W1OA 3WYLA 3SL6A 2QYLA 4MSNA 5AXPA 2OUVA 3HQYA 4WCUA 1XOQA 3O0JA 1XORA 4P0NA 4TPMA 1RORA 5K32A 3V94A 4G2YA 5EDGB 3B2RA 5C2EA 3W5EA 3HMVA 5C29A 4I9ZA 3V93A 4D08A 1OYNA 4G2JA 3ITUA 2OUQA 4YQHA 2FM0A 2QYNA 3KKTA 4MUWA 5B4LA 3SHZA 5C2AA 4WN1A 4G2LA 2QYMA 2OVVA 3IAKA 3G4KA 3HR1A 3O56A 4LM4A 3HQZA 4MYQA 4NPVA 4LM0A 4NPWA 4OEWA 4Y2BA 4HTZA 4XY2A 4MSAA 5I2RA 1RO9A 4PHWA 1XOMA 3K3EA 4MS0A 5AXQA 1XN0A 4FCDA 3SIEA 4YS7A 1TBFA 4P1RA 1Y2JA 5EDIA 4I15A 4NW7A 3QI3A 4LM1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3JWR A;  1XOT A;  3TGG A;  1TB5 A;  1Y2E A;  1XMY A;  1ZKL A;  1SO2 A;  4LM3 A;  3SL3 A;  5EDH A;  4JIB A;  5DH4 A;  3SL8 A;  5EDI B;  3WYM A;  1MKD A;  3DYN A;  4MSH A;  3SNL A;  3WD9 A;  1XP0 A;  2H44 A;  3DYS A;  2CHM A;  2WEY A;  1TB7 A;  1Y2C A;  3IAD A;  3JWQ A;  3GWT A;  3QPN A;  4LLX A;  5K9R A;  4LLP A;  3ECM A;  4DDL A;  3K4S A;  1Z1L A;  1PTW A;  4LKQ A;  4QGE A;  1TBB A;  1T9S A;  2OUU A;  3N3Z A;  3HQW A;  3SHY A;  1RO6 A;  3SNI A;  4KP6 A;  4GH6 A;  1XMY B;  1Q9M A;  4D09 A;  4PHL A;  3HDZ A;  5EDE A;  3G58 A;  4MVH A;  3DYQ A;  3QI4 A;  3G4L A;  2FM5 A;  1Y2D A;  3SL4 A;  4DFF A;  1XM4 A;  3ITM A;  4C1I A;  3G4G A;  4MRZ A;  2OUR A;  4AJD A;  3ECN A;  4MSC A;  3G45 A;  1XM6 A;  4X0F A;  4OEX A;  1RKP A;  3IBJ A;  1XLZ A;  2OUS A;  2OVY A;  5C2H A;  3TVX A;  3WS8 A;  2OUP A;  2OUN A;  3WYK A;  4PM0 A;  5C28 A;  4OGB A;  5EDE B;  1XMU B;  4HF4 A;  4AEL A;  4Y87 A;  3D3P A;  2QYK A;  1F0J A;  2OUY A;  3SN7 A;  5C1W A;  1XOZ A;  1XM4 B;  4HEU A;  3LXG A;  5K1I A;  4MSE A;  3HC8 A;  5DH5 A;  3G4I A;  3WI2 A;  3TGE A;  1SOJ A;  4WZI A;  4HTX A;  1XMU A;  4LLJ A;  1TAZ A;  2Y0J A;  4AJM A;  1T9R A;  2HD1 A;  4IA0 A;  3LY2 A;  1XOS A;  2YY2 A;  3DY8 A;  4LLK A;  1XLX A;  4FCB A;  4AJG A;  3K3H A;  1Y2H A;  4Y8C A;  4Y86 A;  3WS9 A;  3QPP A;  3G3N A;  3V9B A;  1UHO A;  5EDG A;  4ZO5 A;  3SL5 A;  2PW3 A;  1XON A;  4MRW A;  2H42 A;  1Y2B A;  2H40 A;  5B4K A;  4AJF A;  1UDT A;  3JSW A;  4TPP A;  4LM2 A;  3JSI A;  1ZKN A;  1UDU A;  3BJC A;  3FRG A;  4MD6 A;  3O57 A;  4G2W A;  2O8H A;  3DYL A;  3UUO A;  1Y2K A;  2R8Q A;  4E90 A;  3UI7 A;  4BBX A;  3I8V A;  5B25 A;  3QPO A;  4W1O A;  3WYL A;  3SL6 A;  2QYL A;  4MSN A;  5AXP A;  2OUV A;  3HQY A;  4WCU A;  1XOQ A;  3O0J A;  1XOR A;  4P0N A;  4TPM A;  1ROR A;  5K32 A;  3V94 A;  4G2Y A;  5EDG B;  3B2R A;  5C2E A;  3W5E A;  3HMV A;  5C29 A;  4I9Z A;  3V93 A;  4D08 A;  1OYN A;  4G2J A;  3ITU A;  2OUQ A;  4YQH A;  2FM0 A;  2QYN A;  3KKT A;  4MUW A;  5B4L A;  3SHZ A;  5C2A A;  4WN1 A;  4G2L A;  2QYM A;  2OVV A;  3IAK A;  3G4K A;  3HR1 A;  3O56 A;  4LM4 A;  3HQZ A;  4MYQ A;  4NPV A;  4LM0 A;  4NPW A;  4OEW A;  4Y2B A;  4HTZ A;  4XY2 A;  4MSA A;  5I2R A;  1RO9 A;  4PHW A;  1XOM A;  3K3E A;  4MS0 A;  5AXQ A;  1XN0 A;  4FCD A;  3SIE A;  4YS7 A;  1TBF A;  4P1R A;  1Y2J A;  5EDI A;  4I15 A;  4NW7 A;  3QI3 A;  4LM1 A; 
#chains in the Genus database with same CATH topology
 3JWR A;  1XOT A;  3TGG A;  1TB5 A;  1Y2E A;  1XMY A;  1ZKL A;  1SO2 A;  4LM3 A;  3SL3 A;  5EDH A;  4JIB A;  5DH4 A;  3SL8 A;  5EDI B;  3WYM A;  1MKD A;  3DYN A;  4MSH A;  3SNL A;  3WD9 A;  1XP0 A;  2H44 A;  3DYS A;  2CHM A;  2WEY A;  1TB7 A;  1Y2C A;  3IAD A;  3JWQ A;  3GWT A;  3QPN A;  4LLX A;  5K9R A;  4LLP A;  3ECM A;  4DDL A;  3K4S A;  1Z1L A;  1PTW A;  4LKQ A;  4QGE A;  1TBB A;  1T9S A;  2OUU A;  3N3Z A;  3HQW A;  3SHY A;  1RO6 A;  3SNI A;  4KP6 A;  4GH6 A;  1XMY B;  1Q9M A;  4D09 A;  4PHL A;  3HDZ A;  5EDE A;  3G58 A;  4MVH A;  3DYQ A;  3QI4 A;  3G4L A;  2FM5 A;  1Y2D A;  3SL4 A;  4DFF A;  1XM4 A;  3ITM A;  4C1I A;  3G4G A;  4MRZ A;  2OUR A;  4AJD A;  3ECN A;  4MSC A;  3G45 A;  1XM6 A;  4X0F A;  4OEX A;  1RKP A;  3IBJ A;  1XLZ A;  2OUS A;  2OVY A;  5C2H A;  3TVX A;  3WS8 A;  2OUP A;  2OUN A;  3WYK A;  4PM0 A;  5C28 A;  4OGB A;  5EDE B;  1XMU B;  4HF4 A;  4AEL A;  4Y87 A;  3D3P A;  2QYK A;  1F0J A;  2OUY A;  3SN7 A;  5C1W A;  1XOZ A;  1XM4 B;  4HEU A;  3LXG A;  5K1I A;  4MSE A;  3HC8 A;  5DH5 A;  3G4I A;  3WI2 A;  3TGE A;  1SOJ A;  4WZI A;  4HTX A;  1XMU A;  4LLJ A;  1TAZ A;  2Y0J A;  4AJM A;  1T9R A;  2HD1 A;  4IA0 A;  3LY2 A;  1XOS A;  2YY2 A;  3DY8 A;  4LLK A;  1XLX A;  4FCB A;  4AJG A;  3K3H A;  1Y2H A;  4Y8C A;  4Y86 A;  3WS9 A;  3QPP A;  3G3N A;  3V9B A;  1UHO A;  5EDG A;  4ZO5 A;  3SL5 A;  2PW3 A;  1XON A;  4MRW A;  2H42 A;  1Y2B A;  2H40 A;  5B4K A;  4AJF A;  1UDT A;  3JSW A;  4TPP A;  4LM2 A;  3JSI A;  1ZKN A;  1UDU A;  3BJC A;  3FRG A;  4MD6 A;  3O57 A;  4G2W A;  2O8H A;  3DYL A;  3UUO A;  1Y2K A;  2R8Q A;  4E90 A;  3UI7 A;  4BBX A;  3I8V A;  5B25 A;  3QPO A;  4W1O A;  3WYL A;  3SL6 A;  2QYL A;  4MSN A;  5AXP A;  2OUV A;  3HQY A;  4WCU A;  1XOQ A;  3O0J A;  1XOR A;  4P0N A;  4TPM A;  1ROR A;  5K32 A;  3V94 A;  4G2Y A;  5EDG B;  3B2R A;  5C2E A;  3W5E A;  3HMV A;  5C29 A;  4I9Z A;  3V93 A;  4D08 A;  1OYN A;  4G2J A;  3ITU A;  2OUQ A;  4YQH A;  2FM0 A;  2QYN A;  3KKT A;  4MUW A;  5B4L A;  3SHZ A;  5C2A A;  4WN1 A;  4G2L A;  2QYM A;  2OVV A;  3IAK A;  3G4K A;  3HR1 A;  3O56 A;  4LM4 A;  3HQZ A;  4MYQ A;  4NPV A;  4LM0 A;  4NPW A;  4OEW A;  4Y2B A;  4HTZ A;  4XY2 A;  4MSA A;  5I2R A;  1RO9 A;  4PHW A;  1XOM A;  3K3E A;  4MS0 A;  5AXQ A;  1XN0 A;  4FCD A;  3SIE A;  4YS7 A;  1TBF A;  4P1R A;  1Y2J A;  5EDI A;  4I15 A;  4NW7 A;  3QI3 A;  4LM1 A; 
#chains in the Genus database with same CATH homology
 3JWR A;  1XOT A;  3TGG A;  1TB5 A;  1Y2E A;  1XMY A;  1ZKL A;  1SO2 A;  4LM3 A;  3SL3 A;  5EDH A;  4JIB A;  5DH4 A;  3SL8 A;  5EDI B;  3WYM A;  1MKD A;  3DYN A;  4MSH A;  3SNL A;  3WD9 A;  1XP0 A;  2H44 A;  3DYS A;  2CHM A;  2WEY A;  1TB7 A;  1Y2C A;  3IAD A;  3JWQ A;  3GWT A;  3QPN A;  4LLX A;  5K9R A;  4LLP A;  3ECM A;  4DDL A;  3K4S A;  1Z1L A;  1PTW A;  4LKQ A;  4QGE A;  1TBB A;  1T9S A;  2OUU A;  3N3Z A;  3HQW A;  3SHY A;  1RO6 A;  3SNI A;  4KP6 A;  4GH6 A;  1XMY B;  1Q9M A;  4D09 A;  4PHL A;  3HDZ A;  5EDE A;  3G58 A;  4MVH A;  3DYQ A;  3QI4 A;  3G4L A;  2FM5 A;  1Y2D A;  3SL4 A;  4DFF A;  1XM4 A;  3ITM A;  4C1I A;  3G4G A;  4MRZ A;  2OUR A;  4AJD A;  3ECN A;  4MSC A;  3G45 A;  1XM6 A;  4X0F A;  4OEX A;  1RKP A;  3IBJ A;  1XLZ A;  2OUS A;  2OVY A;  5C2H A;  3TVX A;  3WS8 A;  2OUP A;  2OUN A;  3WYK A;  4PM0 A;  5C28 A;  4OGB A;  5EDE B;  1XMU B;  4HF4 A;  4AEL A;  4Y87 A;  3D3P A;  2QYK A;  1F0J A;  2OUY A;  3SN7 A;  5C1W A;  1XOZ A;  1XM4 B;  4HEU A;  3LXG A;  5K1I A;  4MSE A;  3HC8 A;  5DH5 A;  3G4I A;  3WI2 A;  3TGE A;  1SOJ A;  4WZI A;  4HTX A;  1XMU A;  4LLJ A;  1TAZ A;  2Y0J A;  4AJM A;  1T9R A;  2HD1 A;  4IA0 A;  3LY2 A;  1XOS A;  2YY2 A;  3DY8 A;  4LLK A;  1XLX A;  4FCB A;  4AJG A;  3K3H A;  1Y2H A;  4Y8C A;  4Y86 A;  3WS9 A;  3QPP A;  3G3N A;  3V9B A;  1UHO A;  5EDG A;  4ZO5 A;  3SL5 A;  2PW3 A;  1XON A;  4MRW A;  2H42 A;  1Y2B A;  2H40 A;  5B4K A;  4AJF A;  1UDT A;  3JSW A;  4TPP A;  4LM2 A;  3JSI A;  1ZKN A;  1UDU A;  3BJC A;  3FRG A;  4MD6 A;  3O57 A;  4G2W A;  2O8H A;  3DYL A;  3UUO A;  1Y2K A;  2R8Q A;  4E90 A;  3UI7 A;  4BBX A;  3I8V A;  5B25 A;  3QPO A;  4W1O A;  3WYL A;  3SL6 A;  2QYL A;  4MSN A;  5AXP A;  2OUV A;  3HQY A;  4WCU A;  1XOQ A;  3O0J A;  1XOR A;  4P0N A;  4TPM A;  1ROR A;  5K32 A;  3V94 A;  4G2Y A;  5EDG B;  3B2R A;  5C2E A;  3W5E A;  3HMV A;  5C29 A;  4I9Z A;  3V93 A;  4D08 A;  1OYN A;  4G2J A;  3ITU A;  2OUQ A;  4YQH A;  2FM0 A;  2QYN A;  3KKT A;  4MUW A;  5B4L A;  3SHZ A;  5C2A A;  4WN1 A;  4G2L A;  2QYM A;  2OVV A;  3IAK A;  3G4K A;  3HR1 A;  3O56 A;  4LM4 A;  3HQZ A;  4MYQ A;  4NPV A;  4LM0 A;  4NPW A;  4OEW A;  4Y2B A;  4HTZ A;  4XY2 A;  4MSA A;  5I2R A;  1RO9 A;  4PHW A;  1XOM A;  3K3E A;  4MS0 A;  5AXQ A;  1XN0 A;  4FCD A;  3SIE A;  4YS7 A;  1TBF A;  4P1R A;  1Y2J A;  5EDI A;  4I15 A;  4NW7 A;  3QI3 A;  4LM1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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