3NVLA

Crystal structure of phosphoglycerate mutase from trypanosoma brucei
Total Genus 199
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
199
Knots found
sequence length
549
structure length
549
Chain Sequence
LTLAAHKTLPRRKLVLVVLDGVGIGPRDEYDAVHVAKTPLMDALFNDPKHFRSICAHGTAVGLPTDADMGNSEVGHNALGAGRVVLQGASLVDDALESGEIFTSEGYRYLHGAFSQPGRTLHLIGLLSDGGVHSRDNQVYQILKHAGANGAKRIRVHALYDGRDVPDKTSFKFTDELEEVLAKLREGGCDARIASGGGRMFVTMDRYEADWSIVERGWRAQVLGEGRAFKSAREALTKFREEDANISDQYYPPFVIAGDDGRPIGTIEDGDAVLCFNFRGDRVIEMSRAFEEEEFDKFNRVRLPKVRYAGMMRYDGDLGIPNNFLVPPPKLTRTSEEYLIGSGCNIFALSETQKFGHVTYFWNGNRSGKLSEERETFCEIPSDRVQFNQKPLMKSKEITDAAVDAIKSGKYDMIRINYPNGDMVGHTGDLKATITSLEAVDQSLQRLKEAVDSVNGVFLITADHGNSDDMVQRDKKGKPVRDAEGNLMPLTSHTLAPVPVFIGGAGLDPRVQMRTDLPRAGLANVTATFINLMGFEAPSDYEPSLIEVA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords 2,3-bisphosphoglycerate-independent phosphoglycerate mutase
publication title Crystal structure of phosphoglycerate mutase from Trypanosoma brucei.
pubmed doi rcsb
source organism Trypanosoma brucei
molecule tags Isomerase
total genus 199
structure length 549
sequence length 549
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 5.4.2.1: Transferred entry: 5.4.2.11 and 5.4.2.12.
pdb deposition date 2010-07-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01676 Metalloenzyme Metalloenzyme superfamily
A PF06415 iPGM_N BPG-independent PGAM N-terminus (iPGM_N)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 3nvlA01
3.40.1450.10 Alpha Beta 3-Layer(aba) Sandwich 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain BPG-independent phosphoglycerate mutase, domain B 3nvlA02
1KH5A 2GLQA 4UORA 2W5QA 5GOVA 4FDIA 4GTWA 1E2SP 4LRDA 4LR2A 2IFYA 3IGYB 1ANIA 4ZGAA 1SHQA 1N2KA 2W5VA 5EGEA 3UN3A 2W8SA 1HQAA 1KH4A 2IUCB 3KD8A 3SZYA 3NKNA 3WAXA 4MY4A 4UOPA 2QZUA 3MK2A 5L0EA 5DLWA 2W5TA 1AJDA 1EJJA 3WBHA 4CYRA 4UPLA 1Y7AA 4LR9A 3T02A 3TG0A 3M8YA 1O98A 3M8ZA 3OT9A 1HDHA 1KHNA 1P49A 4LRCA 1ELYA 2W5XA 3ED4A 5DLTA 5EGHA 1N2LA 2D1GA 1ELXA 1SHNA 1Y6VA 1O99A 1K7HA 5L0KA 1AJAA 4LR7A 5HRTA 1ANJA 4CXKA 3T01A 1EW9A 3Q3QA 4KAYA 3BDGB 3BDHA 2GSNA 1KH9A 3NKOA 4LRBA 3UN2A 4B56A 1ALJA 1ZEBA 4MIVA 4UOOA 4ZG9A 1HJKA 2ANHA 2XRGA 3E2DA 4LRAA 3B5QA 4ZG7A 5LQQA 5INHA 1URBA 1ED9A 1AUKA 2GSUA 3DYCA 3BDFA 3IDDA 4MHXA 1AJCA 1EW8A 1KH7A 4LRFA 4KM4A 1KHLA 1E1ZP 3MK1A 3NKMA 3BDGA 5L0BA 2ZKTA 4NWXA 3UN5A 4GTYA 3WAWA 4FDJA 1ALKA 4N7TA 3LXQA 3WAYA 5TJ3A 1KHJA 1B8JA 3MK0A 5KXAA 1EQJA 3CMRA 4KJGA 2XR9A 4GTXA 1ELZA 5LRMA 5IJQA 2X98A 2W5RA 3M8WA 4CXUA 4LR8A 1ED8A 1ZEFA 2VQRA 4KAVA 5K4PA 4UPHA 3SZZA 4CXSA 1URAA 1EI6A 1ALIA 2W5SA 4LQYA 3UNYA 4UPKA 3IGZB 2GA3A 5LIAA 1FSUA 4GTZA 3T00A 4TN0A 1KHKA 1ZEDA 4NWJA 1EW2A 2W8DA 1AJBA 2G9YA 3NKQA 3UO0A 1ALHA 3M7VA 5LRNA 4ZG6A 2IUCA 4LREA 3NKPA 5DLVA 4QAXA 4CYSA 3A52A 5IJSA 2RH6A 3TWZA 2GSOA 5C66A 4KJDA 3NVLA 4UPIA 1E3CP 4YR1A 3WAVA 2W5WA 3NKRA 5AJ9A 3TX0A 5GRRA 3DPCA 1E33P
chains in the Genus database with same CATH superfamily
1KH5A 2GLQA 4UORA 2W5QA 5GOVA 4FDIA 4GTWA 1E2SP 4LRDA 4LR2A 2IFYA 3IGYB 1ANIA 4ZGAA 1SHQA 1N2KA 2W5VA 5EGEA 3UN3A 2W8SA 1HQAA 1KH4A 2IUCB 3KD8A 3SZYA 3NKNA 3WAXA 4MY4A 4UOPA 2QZUA 3MK2A 5L0EA 5DLWA 2W5TA 1AJDA 1EJJA 3WBHA 4CYRA 4UPLA 1Y7AA 4LR9A 3T02A 3TG0A 3M8YA 1O98A 3M8ZA 3OT9A 1HDHA 1KHNA 1P49A 4LRCA 1ELYA 2W5XA 3ED4A 5DLTA 5EGHA 1N2LA 2D1GA 1ELXA 1SHNA 1Y6VA 1O99A 1K7HA 5L0KA 1AJAA 4LR7A 5HRTA 1ANJA 4CXKA 3T01A 1EW9A 3Q3QA 4KAYA 3BDGB 3BDHA 2GSNA 1KH9A 3NKOA 4LRBA 3UN2A 4B56A 1ALJA 1ZEBA 4MIVA 4UOOA 4ZG9A 1HJKA 2ANHA 2XRGA 3E2DA 4LRAA 3B5QA 4ZG7A 5LQQA 5INHA 1URBA 1ED9A 1AUKA 2GSUA 3DYCA 3BDFA 3IDDA 4MHXA 1AJCA 1EW8A 1KH7A 4LRFA 4KM4A 1KHLA 1E1ZP 3MK1A 3NKMA 3BDGA 5L0BA 2ZKTA 4NWXA 3UN5A 4GTYA 3WAWA 4FDJA 1ALKA 4N7TA 3LXQA 3WAYA 5TJ3A 1KHJA 1B8JA 3MK0A 5KXAA 1EQJA 3CMRA 4KJGA 2XR9A 4GTXA 1ELZA 5LRMA 5IJQA 2X98A 2W5RA 3M8WA 4CXUA 4LR8A 1ED8A 1ZEFA 2VQRA 4KAVA 5K4PA 4UPHA 3SZZA 4CXSA 1URAA 1EI6A 1ALIA 2W5SA 4LQYA 3UNYA 4UPKA 3IGZB 2GA3A 5LIAA 1FSUA 4GTZA 3T00A 4TN0A 1KHKA 1ZEDA 4NWJA 1EW2A 2W8DA 1AJBA 2G9YA 3NKQA 3UO0A 1ALHA 3M7VA 5LRNA 4ZG6A 2IUCA 4LREA 3NKPA 5DLVA 4QAXA 4CYSA 3A52A 5IJSA 2RH6A 3TWZA 2GSOA 5C66A 4KJDA 3NVLA 4UPIA 1E3CP 4YR1A 3WAVA 2W5WA 3NKRA 5AJ9A 3TX0A 5GRRA 3DPCA 1E33P
chains in the Genus database with same CATH topology
1KH5A 2GLQA 4UORA 2W5QA 5GOVA 4FDIA 4GTWA 1E2SP 4LRDA 4LR2A 2IFYA 3IGYB 1ANIA 4ZGAA 1SHQA 1N2KA 2W5VA 5EGEA 3UN3A 2W8SA 1HQAA 1KH4A 2IUCB 3KD8A 3SZYA 3NKNA 3WAXA 4MY4A 4UOPA 2QZUA 3MK2A 5L0EA 5DLWA 2W5TA 1AJDA 1EJJA 3WBHA 4CYRA 4UPLA 1Y7AA 4LR9A 3T02A 3TG0A 3M8YA 1O98A 3M8ZA 3OT9A 1HDHA 1KHNA 1P49A 4LRCA 1ELYA 2W5XA 3ED4A 5DLTA 5EGHA 1N2LA 2D1GA 1ELXA 1SHNA 1Y6VA 1O99A 1K7HA 5L0KA 1AJAA 4LR7A 5HRTA 1ANJA 4CXKA 3T01A 1EW9A 3Q3QA 4KAYA 3BDGB 3BDHA 2GSNA 1KH9A 3NKOA 4LRBA 3UN2A 4B56A 1ALJA 1ZEBA 4MIVA 4UOOA 4ZG9A 1HJKA 2ANHA 2XRGA 3E2DA 4LRAA 3B5QA 4ZG7A 5LQQA 5INHA 1URBA 1ED9A 1AUKA 2GSUA 3DYCA 3BDFA 3IDDA 4MHXA 1AJCA 1EW8A 1KH7A 4LRFA 4KM4A 1KHLA 1E1ZP 3MK1A 3NKMA 3BDGA 5L0BA 2ZKTA 4NWXA 3UN5A 4GTYA 3WAWA 4FDJA 1ALKA 4N7TA 3LXQA 3WAYA 5TJ3A 1KHJA 1B8JA 3MK0A 5KXAA 1EQJA 3CMRA 4KJGA 2XR9A 4GTXA 1ELZA 5LRMA 5IJQA 2X98A 2W5RA 3M8WA 4CXUA 4LR8A 1ED8A 1ZEFA 2VQRA 4KAVA 5K4PA 4UPHA 3SZZA 4CXSA 1URAA 1EI6A 1ALIA 2W5SA 4LQYA 3UNYA 4UPKA 3IGZB 2GA3A 5LIAA 1FSUA 4GTZA 3T00A 4TN0A 1KHKA 1ZEDA 4NWJA 1EW2A 2W8DA 1AJBA 2G9YA 3NKQA 3UO0A 1ALHA 3M7VA 5LRNA 4ZG6A 2IUCA 4LREA 3NKPA 5DLVA 4QAXA 4CYSA 3A52A 5IJSA 2RH6A 3TWZA 2GSOA 5C66A 4KJDA 3NVLA 4UPIA 1E3CP 4YR1A 3WAVA 2W5WA 3NKRA 5AJ9A 3TX0A 5GRRA 3DPCA 1E33P
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KH5 A;  2GLQ A;  4UOR A;  2W5Q A;  5GOV A;  4FDI A;  4GTW A;  1E2S P;  4LRD A;  4LR2 A;  2IFY A;  3IGY B;  1ANI A;  4ZGA A;  1SHQ A;  1N2K A;  2W5V A;  5EGE A;  3UN3 A;  2W8S A;  1HQA A;  1KH4 A;  2IUC B;  3KD8 A;  3SZY A;  3NKN A;  3WAX A;  4MY4 A;  4UOP A;  2QZU A;  3MK2 A;  5L0E A;  5DLW A;  2W5T A;  1AJD A;  1EJJ A;  3WBH A;  4CYR A;  4UPL A;  1Y7A A;  4LR9 A;  3T02 A;  3TG0 A;  3M8Y A;  1O98 A;  3M8Z A;  3OT9 A;  1HDH A;  1KHN A;  1P49 A;  4LRC A;  1ELY A;  2W5X A;  3ED4 A;  5DLT A;  5EGH A;  1N2L A;  2D1G A;  1ELX A;  1SHN A;  1Y6V A;  1O99 A;  1K7H A;  5L0K A;  1AJA A;  4LR7 A;  5HRT A;  1ANJ A;  4CXK A;  3T01 A;  1EW9 A;  3Q3Q A;  4KAY A;  3BDG B;  3BDH A;  2GSN A;  1KH9 A;  3NKO A;  4LRB A;  3UN2 A;  4B56 A;  1ALJ A;  1ZEB A;  4MIV A;  4UOO A;  4ZG9 A;  1HJK A;  2ANH A;  2XRG A;  3E2D A;  4LRA A;  3B5Q A;  4ZG7 A;  5LQQ A;  5INH A;  1URB A;  1ED9 A;  1AUK A;  2GSU A;  3DYC A;  3BDF A;  3IDD A;  4MHX A;  1AJC A;  1EW8 A;  1KH7 A;  4LRF A;  4KM4 A;  1KHL A;  1E1Z P;  3MK1 A;  3NKM A;  3BDG A;  5L0B A;  2ZKT A;  4NWX A;  3UN5 A;  4GTY A;  3WAW A;  4FDJ A;  1ALK A;  4N7T A;  3LXQ A;  3WAY A;  5TJ3 A;  1KHJ A;  1B8J A;  3MK0 A;  5KXA A;  1EQJ A;  3CMR A;  4KJG A;  2XR9 A;  4GTX A;  1ELZ A;  5LRM A;  5IJQ A;  2X98 A;  2W5R A;  3M8W A;  4CXU A;  4LR8 A;  1ED8 A;  1ZEF A;  2VQR A;  4KAV A;  5K4P A;  4UPH A;  3SZZ A;  4CXS A;  1URA A;  1EI6 A;  1ALI A;  2W5S A;  4LQY A;  3UNY A;  4UPK A;  3IGZ B;  2GA3 A;  5LIA A;  1FSU A;  4GTZ A;  3T00 A;  4TN0 A;  1KHK A;  1ZED A;  4NWJ A;  1EW2 A;  2W8D A;  1AJB A;  2G9Y A;  3NKQ A;  3UO0 A;  1ALH A;  3M7V A;  5LRN A;  4ZG6 A;  2IUC A;  4LRE A;  3NKP A;  5DLV A;  4QAX A;  4CYS A;  3A52 A;  5IJS A;  2RH6 A;  3TWZ A;  2GSO A;  5C66 A;  4KJD A;  3NVL A;  4UPI A;  1E3C P;  4YR1 A;  3WAV A;  2W5W A;  3NKR A;  5AJ9 A;  3TX0 A;  5GRR A;  3DPC A;  1E33 P; 
#chains in the Genus database with same CATH topology
 1KH5 A;  2GLQ A;  4UOR A;  2W5Q A;  5GOV A;  4FDI A;  4GTW A;  1E2S P;  4LRD A;  4LR2 A;  2IFY A;  3IGY B;  1ANI A;  4ZGA A;  1SHQ A;  1N2K A;  2W5V A;  5EGE A;  3UN3 A;  2W8S A;  1HQA A;  1KH4 A;  2IUC B;  3KD8 A;  3SZY A;  3NKN A;  3WAX A;  4MY4 A;  4UOP A;  2QZU A;  3MK2 A;  5L0E A;  5DLW A;  2W5T A;  1AJD A;  1EJJ A;  3WBH A;  4CYR A;  4UPL A;  1Y7A A;  4LR9 A;  3T02 A;  3TG0 A;  3M8Y A;  1O98 A;  3M8Z A;  3OT9 A;  1HDH A;  1KHN A;  1P49 A;  4LRC A;  1ELY A;  2W5X A;  3ED4 A;  5DLT A;  5EGH A;  1N2L A;  2D1G A;  1ELX A;  1SHN A;  1Y6V A;  1O99 A;  1K7H A;  5L0K A;  1AJA A;  4LR7 A;  5HRT A;  1ANJ A;  4CXK A;  3T01 A;  1EW9 A;  3Q3Q A;  4KAY A;  3BDG B;  3BDH A;  2GSN A;  1KH9 A;  3NKO A;  4LRB A;  3UN2 A;  4B56 A;  1ALJ A;  1ZEB A;  4MIV A;  4UOO A;  4ZG9 A;  1HJK A;  2ANH A;  2XRG A;  3E2D A;  4LRA A;  3B5Q A;  4ZG7 A;  5LQQ A;  5INH A;  1URB A;  1ED9 A;  1AUK A;  2GSU A;  3DYC A;  3BDF A;  3IDD A;  4MHX A;  1AJC A;  1EW8 A;  1KH7 A;  4LRF A;  4KM4 A;  1KHL A;  1E1Z P;  3MK1 A;  3NKM A;  3BDG A;  5L0B A;  2ZKT A;  4NWX A;  3UN5 A;  4GTY A;  3WAW A;  4FDJ A;  1ALK A;  4N7T A;  3LXQ A;  3WAY A;  5TJ3 A;  1KHJ A;  1B8J A;  3MK0 A;  5KXA A;  1EQJ A;  3CMR A;  4KJG A;  2XR9 A;  4GTX A;  1ELZ A;  5LRM A;  5IJQ A;  2X98 A;  2W5R A;  3M8W A;  4CXU A;  4LR8 A;  1ED8 A;  1ZEF A;  2VQR A;  4KAV A;  5K4P A;  4UPH A;  3SZZ A;  4CXS A;  1URA A;  1EI6 A;  1ALI A;  2W5S A;  4LQY A;  3UNY A;  4UPK A;  3IGZ B;  2GA3 A;  5LIA A;  1FSU A;  4GTZ A;  3T00 A;  4TN0 A;  1KHK A;  1ZED A;  4NWJ A;  1EW2 A;  2W8D A;  1AJB A;  2G9Y A;  3NKQ A;  3UO0 A;  1ALH A;  3M7V A;  5LRN A;  4ZG6 A;  2IUC A;  4LRE A;  3NKP A;  5DLV A;  4QAX A;  4CYS A;  3A52 A;  5IJS A;  2RH6 A;  3TWZ A;  2GSO A;  5C66 A;  4KJD A;  3NVL A;  4UPI A;  1E3C P;  4YR1 A;  3WAV A;  2W5W A;  3NKR A;  5AJ9 A;  3TX0 A;  5GRR A;  3DPC A;  1E33 P; 
#chains in the Genus database with same CATH homology
 1KH5 A;  2GLQ A;  4UOR A;  2W5Q A;  5GOV A;  4FDI A;  4GTW A;  1E2S P;  4LRD A;  4LR2 A;  2IFY A;  3IGY B;  1ANI A;  4ZGA A;  1SHQ A;  1N2K A;  2W5V A;  5EGE A;  3UN3 A;  2W8S A;  1HQA A;  1KH4 A;  2IUC B;  3KD8 A;  3SZY A;  3NKN A;  3WAX A;  4MY4 A;  4UOP A;  2QZU A;  3MK2 A;  5L0E A;  5DLW A;  2W5T A;  1AJD A;  1EJJ A;  3WBH A;  4CYR A;  4UPL A;  1Y7A A;  4LR9 A;  3T02 A;  3TG0 A;  3M8Y A;  1O98 A;  3M8Z A;  3OT9 A;  1HDH A;  1KHN A;  1P49 A;  4LRC A;  1ELY A;  2W5X A;  3ED4 A;  5DLT A;  5EGH A;  1N2L A;  2D1G A;  1ELX A;  1SHN A;  1Y6V A;  1O99 A;  1K7H A;  5L0K A;  1AJA A;  4LR7 A;  5HRT A;  1ANJ A;  4CXK A;  3T01 A;  1EW9 A;  3Q3Q A;  4KAY A;  3BDG B;  3BDH A;  2GSN A;  1KH9 A;  3NKO A;  4LRB A;  3UN2 A;  4B56 A;  1ALJ A;  1ZEB A;  4MIV A;  4UOO A;  4ZG9 A;  1HJK A;  2ANH A;  2XRG A;  3E2D A;  4LRA A;  3B5Q A;  4ZG7 A;  5LQQ A;  5INH A;  1URB A;  1ED9 A;  1AUK A;  2GSU A;  3DYC A;  3BDF A;  3IDD A;  4MHX A;  1AJC A;  1EW8 A;  1KH7 A;  4LRF A;  4KM4 A;  1KHL A;  1E1Z P;  3MK1 A;  3NKM A;  3BDG A;  5L0B A;  2ZKT A;  4NWX A;  3UN5 A;  4GTY A;  3WAW A;  4FDJ A;  1ALK A;  4N7T A;  3LXQ A;  3WAY A;  5TJ3 A;  1KHJ A;  1B8J A;  3MK0 A;  5KXA A;  1EQJ A;  3CMR A;  4KJG A;  2XR9 A;  4GTX A;  1ELZ A;  5LRM A;  5IJQ A;  2X98 A;  2W5R A;  3M8W A;  4CXU A;  4LR8 A;  1ED8 A;  1ZEF A;  2VQR A;  4KAV A;  5K4P A;  4UPH A;  3SZZ A;  4CXS A;  1URA A;  1EI6 A;  1ALI A;  2W5S A;  4LQY A;  3UNY A;  4UPK A;  3IGZ B;  2GA3 A;  5LIA A;  1FSU A;  4GTZ A;  3T00 A;  4TN0 A;  1KHK A;  1ZED A;  4NWJ A;  1EW2 A;  2W8D A;  1AJB A;  2G9Y A;  3NKQ A;  3UO0 A;  1ALH A;  3M7V A;  5LRN A;  4ZG6 A;  2IUC A;  4LRE A;  3NKP A;  5DLV A;  4QAX A;  4CYS A;  3A52 A;  5IJS A;  2RH6 A;  3TWZ A;  2GSO A;  5C66 A;  4KJD A;  3NVL A;  4UPI A;  1E3C P;  4YR1 A;  3WAV A;  2W5W A;  3NKR A;  5AJ9 A;  3TX0 A;  5GRR A;  3DPC A;  1E33 P; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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