4EKDB

Structure of human regulator of g protein signaling 2 (rgs2) in complex with murine galpha-q(r183c)
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
132
structure length
132
Chain Sequence
FGSPSPEEAQLWSEAFDELLASKYGLAAFRAFLKSEFCEENIEFWLACEDFKKTKSPQKLSSKARKIYTDFIEKEAPKEINIDFQTKTLIAQNIQEATSGCFTTAQKRVYSLMENNSYPRFLESEFYQDLCK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein/inhibitor
molecule keywords Guanine nucleotide-binding protein G(q) subunit alpha
publication title Structural and functional analysis of the regulator of G protein signaling 2-g alpha q complex.
pubmed doi rcsb
source organism Mus musculus
total genus 43
structure length 132
sequence length 132
ec nomenclature
pdb deposition date 2012-04-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 4ekdB02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 4ekdB01
1AGRE 2CRPA 3C7LA 3NYNA 3CIKA 2D9JA 2IHBB 1OMWA 4TNDA 3PSCA 2DLVA 3V5WA 5DO9B 5HE2A 2IHDA 4PNKA 5HE1A 2JM5A 1EMUA 2BCJA 1EZTA 4MK0A 5HE0A 2BV1A 3C7KB 4EKDB 2JNUA 2V4ZB 3UZTA 2ODEB 1DK8A 2EBZA 3PVUA 1FQKB 1EZYA 2BT2A 1FQIA 2OWIA 3NYOA 5HE3A 2AF0A 1FQJB 1CMZA 2OJ4A 2IK8B 3KRXA 4TNBA 2GTPC 3PVWA 3KRWA
chains in the Genus database with same CATH superfamily
1AGRE 2CRPA 3C7LA 3NYNA 5REQB 3CIKA 2D9JA 2IHBB 1OMWA 4TNDA 3PSCA 2DLVA 3V5WA 5DO9B 5HE2A 3QYFA 2IHDA 4PNKA 5HE1A 2JM5A 1EMUA 2BCJA 1EZTA 4MK0A 5HE0A 2BV1A 3C7KB 4EKDB 2JNUA 2V4ZB 3UZTA 3I5QA 2ODEB 1DK8A 2EBZA 3PVUA 1FQKB 1EZYA 2BT2A 1FQIA 2OWIA 3NYOA 4HTEA 5HE3A 2AF0A 1FQJB 1CMZA 2OJ4A 2IK8B 3KRXA 4TNBA 2GTPC 3PVWA 3KRWA
chains in the Genus database with same CATH topology
1AGRE 2CRPA 3C7LA 3NYNA 5REQB 3CIKA 2D9JA 2IHBB 1OMWA 4TNDA 3PSCA 2DLVA 3V5WA 5DO9B 5HE2A 3QYFA 2IHDA 4PNKA 5HE1A 2JM5A 1EMUA 2BCJA 1EZTA 4MK0A 5HE0A 2BV1A 3C7KB 4EKDB 2JNUA 2V4ZB 3UZTA 2ODEB 1DK8A 2EBZA 3PVUA 1FQKB 1EZYA 2BT2A 1FQIA 2OWIA 3NYOA 5HE3A 2AF0A 1FQJB 1CMZA 2OJ4A 2IK8B 3KRXA 4TNBA 2GTPC 3PVWA 3KRWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1AGR E;  2CRP A;  3C7L A;  3NYN A;  3CIK A;  2D9J A;  2IHB B;  1OMW A;  4TND A;  3PSC A;  2DLV A;  3V5W A;  5DO9 B;  5HE2 A;  2IHD A;  4PNK A;  5HE1 A;  2JM5 A;  1EMU A;  2BCJ A;  1EZT A;  4MK0 A;  5HE0 A;  2BV1 A;  3C7K B;  4EKD B;  2JNU A;  2V4Z B;  3UZT A;  2ODE B;  1DK8 A;  2EBZ A;  3PVU A;  1FQK B;  1EZY A;  2BT2 A;  1FQI A;  2OWI A;  3NYO A;  5HE3 A;  2AF0 A;  1FQJ B;  1CMZ A;  2OJ4 A;  2IK8 B;  3KRX A;  4TNB A;  2GTP C;  3PVW A;  3KRW A; 
#chains in the Genus database with same CATH topology
 1AGR E;  2CRP A;  3C7L A;  3NYN A;  5REQ B;  3CIK A;  2D9J A;  2IHB B;  1OMW A;  4TND A;  3PSC A;  2DLV A;  3V5W A;  5DO9 B;  5HE2 A;  3QYF A;  2IHD A;  4PNK A;  5HE1 A;  2JM5 A;  1EMU A;  2BCJ A;  1EZT A;  4MK0 A;  5HE0 A;  2BV1 A;  3C7K B;  4EKD B;  2JNU A;  2V4Z B;  3UZT A;  3I5Q A;  2ODE B;  1DK8 A;  2EBZ A;  3PVU A;  1FQK B;  1EZY A;  2BT2 A;  1FQI A;  2OWI A;  3NYO A;  4HTE A;  5HE3 A;  2AF0 A;  1FQJ B;  1CMZ A;  2OJ4 A;  2IK8 B;  3KRX A;  4TNB A;  2GTP C;  3PVW A;  3KRW A; 
#chains in the Genus database with same CATH homology
 1AGR E;  2CRP A;  3C7L A;  3NYN A;  5REQ B;  3CIK A;  2D9J A;  2IHB B;  1OMW A;  4TND A;  3PSC A;  2DLV A;  3V5W A;  5DO9 B;  5HE2 A;  3QYF A;  2IHD A;  4PNK A;  5HE1 A;  2JM5 A;  1EMU A;  2BCJ A;  1EZT A;  4MK0 A;  5HE0 A;  2BV1 A;  3C7K B;  4EKD B;  2JNU A;  2V4Z B;  3UZT A;  2ODE B;  1DK8 A;  2EBZ A;  3PVU A;  1FQK B;  1EZY A;  2BT2 A;  1FQI A;  2OWI A;  3NYO A;  5HE3 A;  2AF0 A;  1FQJ B;  1CMZ A;  2OJ4 A;  2IK8 B;  3KRX A;  4TNB A;  2GTP C;  3PVW A;  3KRW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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