4HW5A

Crystal structure of the human c3a anaphylatoxin
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
77
structure length
77
Chain Sequence
SVQLTEKRMDKVGKYPKELRKCCEDGMRENPMRFSCQRRTRFISLGEACKKVFLDCCNYITELRRQHARASHLGLAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Immune system
molecule keywords Complement C3
publication title Human C3a and C3a desArg anaphylatoxins have conserved structures, in contrast to C5a and C5a desArg.
pubmed doi rcsb
source organism Homo sapiens
total genus 24
structure length 77
sequence length 77
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-11-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01821 ANATO Anaphylotoxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.91.20 Mainly Alpha Up-down Bundle Influenza Virus Matrix Protein; Chain A, domain 1 Anaphylotoxins (complement system) 4hw5A00
4P39A 2B39A 4HWJA 4HW5A 4UU9C 4WB3A 1CFAA 3CU7A 4I6OA 4P3BA 1C5AA 3KLSA 2A73B 5B4PB 3HQBA 1KJSA 3HQAA 4P3AA 4FXKB 5JPNB 4WB2A
chains in the Genus database with same CATH superfamily
3VDXA 5CQEA 4P39A 2B39A 4HWJA 4FXGB 4HW5A 4UU9C 1AA7A 4WB3A 1CFAA 4D9JA 3CU7A 4I6OA 4P3BA 2Z16A 1C5AA 3KLSA 2A73B 5B4PB 5JPMB 4PUSA 4ITVA 4IQ4A 3HQBA 1EA3A 1KJSA 3HQAA 4P3AA 4FXKB 5JPNB 4WB2A 3MD2A
chains in the Genus database with same CATH topology
4P39A 2B39A 4HWJA 4HW5A 4UU9C 4WB3A 1CFAA 3CU7A 4I6OA 4P3BA 1C5AA 3KLSA 2A73B 5B4PB 3HQBA 1KJSA 3HQAA 4P3AA 4FXKB 5JPNB 4WB2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4P39 A;  2B39 A;  4HWJ A;  4HW5 A;  4UU9 C;  4WB3 A;  1CFA A;  3CU7 A;  4I6O A;  4P3B A;  1C5A A;  3KLS A;  2A73 B;  5B4P B;  3HQB A;  1KJS A;  3HQA A;  4P3A A;  4FXK B;  5JPN B;  4WB2 A; 
#chains in the Genus database with same CATH topology
 3VDX A;  5CQE A;  4P39 A;  2B39 A;  4HWJ A;  4FXG B;  4HW5 A;  4UU9 C;  1AA7 A;  4WB3 A;  1CFA A;  4D9J A;  3CU7 A;  4I6O A;  4P3B A;  2Z16 A;  1C5A A;  3KLS A;  2A73 B;  5B4P B;  5JPM B;  4PUS A;  4ITV A;  4IQ4 A;  3HQB A;  1EA3 A;  1KJS A;  3HQA A;  4P3A A;  4FXK B;  5JPN B;  4WB2 A;  3MD2 A; 
#chains in the Genus database with same CATH homology
 4P39 A;  2B39 A;  4HWJ A;  4HW5 A;  4UU9 C;  4WB3 A;  1CFA A;  3CU7 A;  4I6O A;  4P3B A;  1C5A A;  3KLS A;  2A73 B;  5B4P B;  3HQB A;  1KJS A;  3HQA A;  4P3A A;  4FXK B;  5JPN B;  4WB2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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