4MIVA

Crystal structure of sulfamidase, crystal form l
Total Genus 169
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
169
Knots found
sequence length
484
structure length
483
Chain Sequence
PRNALLLLADDGGFESGAYNNSAIATPHLDALARRSLLFRNAFTSVSSSPSRASLLTGLPQHQNGMYGLHQDVHHFNSFDKVRSLPLLLSQAGVRTGIIGKKHVGPETVYPFDFAYTEENGSVLQVGRNITRIKLLVRKFLQTQDDRPFFLYVAFHDPHRCGHSQPQYGTFCEKFGNGESGMGRIPDWTPQAYDPLDVLVPYFVPNTPAARADLAAQYTTVGRMDQGVGLVLQELRDAGVLNDTLVIFTSDNGIPFPSGRTNLYWPGTAEPLLVSSPEHPKRWGQVSEAYVSLLDLTPTILDWFSIPYPSYAIFGSKTIHLTGRSLLPALEAEPLWATVFGSQSHHEVTMSYPMRSVQHRHFRLVHNLNFKMPFPIDQDFYVSPTFQDLLNRTTAGQPTGWYKDLRHYYYRARWELYDRSRDPHETQNLATDPRFAQLLEMLRDQLAKWQWETHDPWVCAPDGVLEEKLSPQCQPLHNELRSH
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords N-sulphoglucosamine sulphohydrolase
publication title Structure of sulfamidase provides insight into the molecular pathology of mucopolysaccharidosis IIIA.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Hydrolase
total genus 169
structure length 483
sequence length 484
chains with identical sequence B, C, D, E, F, G, H
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.10.1.1: N-sulfoglucosamine sulfohydrolase.
pdb deposition date 2013-09-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00884 Sulfatase Sulfatase
A PF16347 DUF4976 Domain of unknown function (DUF4976)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 4mivA01
3TX0A 4LR2A 1E3CP 1SHQA 3TG0A 1ALHA 3NVLA 3SZYA 5IJQA 4UPIA 3T02A 4FDJA 3WAXA 4CXSA 1HJKA 3A52A 3WAYA 1AUKA 5DLVA 4KAYA 2X98A 4LR9A 2W5VA 3WAVA 1EI6A 2W5RA 4LRCA 3LXQA 3NKNA 3B5QA 3SZZA 2W5SA 2W5QA 5INHA 1N2KA 1P49A 5K4PA 1O98A 2GSUA 4YR1A 3NKPA 1FSUA 3BDHA 3OT9A 1ED9A 1ALKA 4UOPA 4NWXA 5LRNA 1AJAA 1URAA 4KM4A 1E1ZP 2GLQA 1ANJA 2IFYA 2IUCB 2XR9A 1SHNA 1HDHA 2RH6A 4KJDA 5IJSA 1ED8A 1KHNA 1ZEDA 1AJCA 1KHJA 3UNYA 1ZEBA 4B56A 3M7VA 1EW8A 1E2SP 3MK2A 4MHXA 1O99A 1E33P 3KD8A 1ELZA 4LREA 4ZG7A 1KH7A 4LRDA 4LR8A 3M8WA 2G9YA 3M8YA 5HRTA 3UN3A 1ANIA 4GTXA 1AJDA 1EQJA 2W5WA 1KH5A 3MK1A 3ED4A 4TN0A 1KH4A 2W5TA 1EJJA 4UORA 3UO0A 3IDDA 1ELXA 3Q3QA 3IGYB 5EGHA 2IUCA 3IGZB 4LQYA 2VQRA 3E2DA 5LRMA 5DLWA 4CXUA 1AJBA 4LR7A 4ZGAA 3TWZA 4CYSA 4GTYA 2GA3A 2ANHA 3NKQA 1Y6VA 5C66A 3NKRA 4LRBA 3DYCA 4CYRA 1ZEFA 4UPLA 4UOOA 4FDIA 3UN2A 4KJGA 5AJ9A 3BDGA 4LRFA 4GTZA 4UPKA 5KXAA 1EW9A 1KHLA 3NKOA 5LQQA 2W5XA 4QAXA 3T00A 1ALIA 1KH9A 4LRAA 3NKMA 2D1GA 1ELYA 4GTWA 2ZKTA 1B8JA 5LIAA 3WAWA 3BDFA 5GRRA 1KHKA 4CXKA 5L0BA 2XRGA 2QZUA 4MY4A 5TJ3A 2GSOA 4UPHA 5L0KA 2GSNA 1HQAA 4MIVA 4KAVA 5DLTA 4ZG6A 2W8SA 4N7TA 5GOVA 1Y7AA 3UN5A 3M8ZA 3CMRA 3BDGB 1EW2A 1URBA 4NWJA 1K7HA 1N2LA 3WBHA 3T01A 4ZG9A 3DPCA 3MK0A 5EGEA 1ALJA 5L0EA 2W8DA
chains in the Genus database with same CATH superfamily
3TX0A 4LR2A 1E3CP 1SHQA 3TG0A 1ALHA 3NVLA 3SZYA 5IJQA 4UPIA 3T02A 4FDJA 3WAXA 4CXSA 1HJKA 3A52A 3WAYA 1AUKA 5DLVA 4KAYA 2X98A 4LR9A 2W5VA 3WAVA 1EI6A 2W5RA 4LRCA 3LXQA 3NKNA 3B5QA 3SZZA 2W5SA 2W5QA 5INHA 1N2KA 1P49A 5K4PA 1O98A 2GSUA 4YR1A 3NKPA 1FSUA 3BDHA 3OT9A 1ED9A 1ALKA 4UOPA 4NWXA 5LRNA 1AJAA 1URAA 4KM4A 1E1ZP 2GLQA 1ANJA 2IFYA 2IUCB 2XR9A 1SHNA 1HDHA 2RH6A 4KJDA 5IJSA 1ED8A 1KHNA 1ZEDA 1AJCA 1KHJA 3UNYA 1ZEBA 4B56A 3M7VA 1EW8A 1E2SP 3MK2A 4MHXA 1O99A 1E33P 3KD8A 1ELZA 4LREA 4ZG7A 1KH7A 4LRDA 4LR8A 3M8WA 2G9YA 3M8YA 5HRTA 3UN3A 1ANIA 4GTXA 1AJDA 1EQJA 2W5WA 1KH5A 3MK1A 3ED4A 4TN0A 1KH4A 2W5TA 1EJJA 4UORA 3UO0A 3IDDA 1ELXA 3Q3QA 3IGYB 5EGHA 2IUCA 3IGZB 4LQYA 2VQRA 3E2DA 5LRMA 5DLWA 4CXUA 1AJBA 4LR7A 4ZGAA 3TWZA 4CYSA 4GTYA 2GA3A 2ANHA 3NKQA 1Y6VA 5C66A 3NKRA 4LRBA 3DYCA 4CYRA 1ZEFA 4UPLA 4UOOA 4FDIA 3UN2A 4KJGA 5AJ9A 3BDGA 4LRFA 4GTZA 4UPKA 5KXAA 1EW9A 1KHLA 3NKOA 5LQQA 2W5XA 4QAXA 3T00A 1ALIA 1KH9A 4LRAA 3NKMA 2D1GA 1ELYA 4GTWA 2ZKTA 1B8JA 5LIAA 3WAWA 3BDFA 5GRRA 1KHKA 4CXKA 5L0BA 2XRGA 2QZUA 4MY4A 5TJ3A 2GSOA 4UPHA 5L0KA 2GSNA 1HQAA 4MIVA 4KAVA 5DLTA 4ZG6A 2W8SA 4N7TA 5GOVA 1Y7AA 3UN5A 3M8ZA 3CMRA 3BDGB 1EW2A 1URBA 4NWJA 1K7HA 1N2LA 3WBHA 3T01A 4ZG9A 3DPCA 3MK0A 5EGEA 1ALJA 5L0EA 2W8DA
chains in the Genus database with same CATH topology
3TX0A 4LR2A 1E3CP 1SHQA 3TG0A 1ALHA 3NVLA 3SZYA 5IJQA 4UPIA 3T02A 4FDJA 3WAXA 4CXSA 1HJKA 3A52A 3WAYA 1AUKA 5DLVA 4KAYA 2X98A 4LR9A 2W5VA 3WAVA 1EI6A 2W5RA 4LRCA 3LXQA 3NKNA 3B5QA 3SZZA 2W5SA 2W5QA 5INHA 1N2KA 1P49A 5K4PA 1O98A 2GSUA 4YR1A 3NKPA 1FSUA 3BDHA 3OT9A 1ED9A 1ALKA 4UOPA 4NWXA 5LRNA 1AJAA 1URAA 4KM4A 1E1ZP 2GLQA 1ANJA 2IFYA 2IUCB 2XR9A 1SHNA 1HDHA 2RH6A 4KJDA 5IJSA 1ED8A 1KHNA 1ZEDA 1AJCA 1KHJA 3UNYA 1ZEBA 4B56A 3M7VA 1EW8A 1E2SP 3MK2A 4MHXA 1O99A 1E33P 3KD8A 1ELZA 4LREA 4ZG7A 1KH7A 4LRDA 4LR8A 3M8WA 2G9YA 3M8YA 5HRTA 3UN3A 1ANIA 4GTXA 1AJDA 1EQJA 2W5WA 1KH5A 3MK1A 3ED4A 4TN0A 1KH4A 2W5TA 1EJJA 4UORA 3UO0A 3IDDA 1ELXA 3Q3QA 3IGYB 5EGHA 2IUCA 3IGZB 4LQYA 2VQRA 3E2DA 5LRMA 5DLWA 4CXUA 1AJBA 4LR7A 4ZGAA 3TWZA 4CYSA 4GTYA 2GA3A 2ANHA 3NKQA 1Y6VA 5C66A 3NKRA 4LRBA 3DYCA 4CYRA 1ZEFA 4UPLA 4UOOA 4FDIA 3UN2A 4KJGA 5AJ9A 3BDGA 4LRFA 4GTZA 4UPKA 5KXAA 1EW9A 1KHLA 3NKOA 5LQQA 2W5XA 4QAXA 3T00A 1ALIA 1KH9A 4LRAA 3NKMA 2D1GA 1ELYA 4GTWA 2ZKTA 1B8JA 5LIAA 3WAWA 3BDFA 5GRRA 1KHKA 4CXKA 5L0BA 2XRGA 2QZUA 4MY4A 5TJ3A 2GSOA 4UPHA 5L0KA 2GSNA 1HQAA 4MIVA 4KAVA 5DLTA 4ZG6A 2W8SA 4N7TA 5GOVA 1Y7AA 3UN5A 3M8ZA 3CMRA 3BDGB 1EW2A 1URBA 4NWJA 1K7HA 1N2LA 3WBHA 3T01A 4ZG9A 3DPCA 3MK0A 5EGEA 1ALJA 5L0EA 2W8DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3TX0 A;  4LR2 A;  1E3C P;  1SHQ A;  3TG0 A;  1ALH A;  3NVL A;  3SZY A;  5IJQ A;  4UPI A;  3T02 A;  4FDJ A;  3WAX A;  4CXS A;  1HJK A;  3A52 A;  3WAY A;  1AUK A;  5DLV A;  4KAY A;  2X98 A;  4LR9 A;  2W5V A;  3WAV A;  1EI6 A;  2W5R A;  4LRC A;  3LXQ A;  3NKN A;  3B5Q A;  3SZZ A;  2W5S A;  2W5Q A;  5INH A;  1N2K A;  1P49 A;  5K4P A;  1O98 A;  2GSU A;  4YR1 A;  3NKP A;  1FSU A;  3BDH A;  3OT9 A;  1ED9 A;  1ALK A;  4UOP A;  4NWX A;  5LRN A;  1AJA A;  1URA A;  4KM4 A;  1E1Z P;  2GLQ A;  1ANJ A;  2IFY A;  2IUC B;  2XR9 A;  1SHN A;  1HDH A;  2RH6 A;  4KJD A;  5IJS A;  1ED8 A;  1KHN A;  1ZED A;  1AJC A;  1KHJ A;  3UNY A;  1ZEB A;  4B56 A;  3M7V A;  1EW8 A;  1E2S P;  3MK2 A;  4MHX A;  1O99 A;  1E33 P;  3KD8 A;  1ELZ A;  4LRE A;  4ZG7 A;  1KH7 A;  4LRD A;  4LR8 A;  3M8W A;  2G9Y A;  3M8Y A;  5HRT A;  3UN3 A;  1ANI A;  4GTX A;  1AJD A;  1EQJ A;  2W5W A;  1KH5 A;  3MK1 A;  3ED4 A;  4TN0 A;  1KH4 A;  2W5T A;  1EJJ A;  4UOR A;  3UO0 A;  3IDD A;  1ELX A;  3Q3Q A;  3IGY B;  5EGH A;  2IUC A;  3IGZ B;  4LQY A;  2VQR A;  3E2D A;  5LRM A;  5DLW A;  4CXU A;  1AJB A;  4LR7 A;  4ZGA A;  3TWZ A;  4CYS A;  4GTY A;  2GA3 A;  2ANH A;  3NKQ A;  1Y6V A;  5C66 A;  3NKR A;  4LRB A;  3DYC A;  4CYR A;  1ZEF A;  4UPL A;  4UOO A;  4FDI A;  3UN2 A;  4KJG A;  5AJ9 A;  3BDG A;  4LRF A;  4GTZ A;  4UPK A;  5KXA A;  1EW9 A;  1KHL A;  3NKO A;  5LQQ A;  2W5X A;  4QAX A;  3T00 A;  1ALI A;  1KH9 A;  4LRA A;  3NKM A;  2D1G A;  1ELY A;  4GTW A;  2ZKT A;  1B8J A;  5LIA A;  3WAW A;  3BDF A;  5GRR A;  1KHK A;  4CXK A;  5L0B A;  2XRG A;  2QZU A;  4MY4 A;  5TJ3 A;  2GSO A;  4UPH A;  5L0K A;  2GSN A;  1HQA A;  4MIV A;  4KAV A;  5DLT A;  4ZG6 A;  2W8S A;  4N7T A;  5GOV A;  1Y7A A;  3UN5 A;  3M8Z A;  3CMR A;  3BDG B;  1EW2 A;  1URB A;  4NWJ A;  1K7H A;  1N2L A;  3WBH A;  3T01 A;  4ZG9 A;  3DPC A;  3MK0 A;  5EGE A;  1ALJ A;  5L0E A;  2W8D A; 
#chains in the Genus database with same CATH topology
 3TX0 A;  4LR2 A;  1E3C P;  1SHQ A;  3TG0 A;  1ALH A;  3NVL A;  3SZY A;  5IJQ A;  4UPI A;  3T02 A;  4FDJ A;  3WAX A;  4CXS A;  1HJK A;  3A52 A;  3WAY A;  1AUK A;  5DLV A;  4KAY A;  2X98 A;  4LR9 A;  2W5V A;  3WAV A;  1EI6 A;  2W5R A;  4LRC A;  3LXQ A;  3NKN A;  3B5Q A;  3SZZ A;  2W5S A;  2W5Q A;  5INH A;  1N2K A;  1P49 A;  5K4P A;  1O98 A;  2GSU A;  4YR1 A;  3NKP A;  1FSU A;  3BDH A;  3OT9 A;  1ED9 A;  1ALK A;  4UOP A;  4NWX A;  5LRN A;  1AJA A;  1URA A;  4KM4 A;  1E1Z P;  2GLQ A;  1ANJ A;  2IFY A;  2IUC B;  2XR9 A;  1SHN A;  1HDH A;  2RH6 A;  4KJD A;  5IJS A;  1ED8 A;  1KHN A;  1ZED A;  1AJC A;  1KHJ A;  3UNY A;  1ZEB A;  4B56 A;  3M7V A;  1EW8 A;  1E2S P;  3MK2 A;  4MHX A;  1O99 A;  1E33 P;  3KD8 A;  1ELZ A;  4LRE A;  4ZG7 A;  1KH7 A;  4LRD A;  4LR8 A;  3M8W A;  2G9Y A;  3M8Y A;  5HRT A;  3UN3 A;  1ANI A;  4GTX A;  1AJD A;  1EQJ A;  2W5W A;  1KH5 A;  3MK1 A;  3ED4 A;  4TN0 A;  1KH4 A;  2W5T A;  1EJJ A;  4UOR A;  3UO0 A;  3IDD A;  1ELX A;  3Q3Q A;  3IGY B;  5EGH A;  2IUC A;  3IGZ B;  4LQY A;  2VQR A;  3E2D A;  5LRM A;  5DLW A;  4CXU A;  1AJB A;  4LR7 A;  4ZGA A;  3TWZ A;  4CYS A;  4GTY A;  2GA3 A;  2ANH A;  3NKQ A;  1Y6V A;  5C66 A;  3NKR A;  4LRB A;  3DYC A;  4CYR A;  1ZEF A;  4UPL A;  4UOO A;  4FDI A;  3UN2 A;  4KJG A;  5AJ9 A;  3BDG A;  4LRF A;  4GTZ A;  4UPK A;  5KXA A;  1EW9 A;  1KHL A;  3NKO A;  5LQQ A;  2W5X A;  4QAX A;  3T00 A;  1ALI A;  1KH9 A;  4LRA A;  3NKM A;  2D1G A;  1ELY A;  4GTW A;  2ZKT A;  1B8J A;  5LIA A;  3WAW A;  3BDF A;  5GRR A;  1KHK A;  4CXK A;  5L0B A;  2XRG A;  2QZU A;  4MY4 A;  5TJ3 A;  2GSO A;  4UPH A;  5L0K A;  2GSN A;  1HQA A;  4MIV A;  4KAV A;  5DLT A;  4ZG6 A;  2W8S A;  4N7T A;  5GOV A;  1Y7A A;  3UN5 A;  3M8Z A;  3CMR A;  3BDG B;  1EW2 A;  1URB A;  4NWJ A;  1K7H A;  1N2L A;  3WBH A;  3T01 A;  4ZG9 A;  3DPC A;  3MK0 A;  5EGE A;  1ALJ A;  5L0E A;  2W8D A; 
#chains in the Genus database with same CATH homology
 3TX0 A;  4LR2 A;  1E3C P;  1SHQ A;  3TG0 A;  1ALH A;  3NVL A;  3SZY A;  5IJQ A;  4UPI A;  3T02 A;  4FDJ A;  3WAX A;  4CXS A;  1HJK A;  3A52 A;  3WAY A;  1AUK A;  5DLV A;  4KAY A;  2X98 A;  4LR9 A;  2W5V A;  3WAV A;  1EI6 A;  2W5R A;  4LRC A;  3LXQ A;  3NKN A;  3B5Q A;  3SZZ A;  2W5S A;  2W5Q A;  5INH A;  1N2K A;  1P49 A;  5K4P A;  1O98 A;  2GSU A;  4YR1 A;  3NKP A;  1FSU A;  3BDH A;  3OT9 A;  1ED9 A;  1ALK A;  4UOP A;  4NWX A;  5LRN A;  1AJA A;  1URA A;  4KM4 A;  1E1Z P;  2GLQ A;  1ANJ A;  2IFY A;  2IUC B;  2XR9 A;  1SHN A;  1HDH A;  2RH6 A;  4KJD A;  5IJS A;  1ED8 A;  1KHN A;  1ZED A;  1AJC A;  1KHJ A;  3UNY A;  1ZEB A;  4B56 A;  3M7V A;  1EW8 A;  1E2S P;  3MK2 A;  4MHX A;  1O99 A;  1E33 P;  3KD8 A;  1ELZ A;  4LRE A;  4ZG7 A;  1KH7 A;  4LRD A;  4LR8 A;  3M8W A;  2G9Y A;  3M8Y A;  5HRT A;  3UN3 A;  1ANI A;  4GTX A;  1AJD A;  1EQJ A;  2W5W A;  1KH5 A;  3MK1 A;  3ED4 A;  4TN0 A;  1KH4 A;  2W5T A;  1EJJ A;  4UOR A;  3UO0 A;  3IDD A;  1ELX A;  3Q3Q A;  3IGY B;  5EGH A;  2IUC A;  3IGZ B;  4LQY A;  2VQR A;  3E2D A;  5LRM A;  5DLW A;  4CXU A;  1AJB A;  4LR7 A;  4ZGA A;  3TWZ A;  4CYS A;  4GTY A;  2GA3 A;  2ANH A;  3NKQ A;  1Y6V A;  5C66 A;  3NKR A;  4LRB A;  3DYC A;  4CYR A;  1ZEF A;  4UPL A;  4UOO A;  4FDI A;  3UN2 A;  4KJG A;  5AJ9 A;  3BDG A;  4LRF A;  4GTZ A;  4UPK A;  5KXA A;  1EW9 A;  1KHL A;  3NKO A;  5LQQ A;  2W5X A;  4QAX A;  3T00 A;  1ALI A;  1KH9 A;  4LRA A;  3NKM A;  2D1G A;  1ELY A;  4GTW A;  2ZKT A;  1B8J A;  5LIA A;  3WAW A;  3BDF A;  5GRR A;  1KHK A;  4CXK A;  5L0B A;  2XRG A;  2QZU A;  4MY4 A;  5TJ3 A;  2GSO A;  4UPH A;  5L0K A;  2GSN A;  1HQA A;  4MIV A;  4KAV A;  5DLT A;  4ZG6 A;  2W8S A;  4N7T A;  5GOV A;  1Y7A A;  3UN5 A;  3M8Z A;  3CMR A;  3BDG B;  1EW2 A;  1URB A;  4NWJ A;  1K7H A;  1N2L A;  3WBH A;  3T01 A;  4ZG9 A;  3DPC A;  3MK0 A;  5EGE A;  1ALJ A;  5L0E A;  2W8D A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...