4QN0A

Crystal structure of the cps-6 mutant q130k
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
239
structure length
238
Chain Sequence
SRSAEIMKHGYPGFTNVRTYEDFVLSYDYKTRTAHWVCEHLTPERLKHAGVDRKLCEFKPDITFPKKFLSQNTDYKCSGFDRGHLAAAGNHRKSQLAVDQTFYLSNMSPQVGRGFNRDKWNDLEMHCRRVAKKMINSYIITGPLYLPKLEGDGKKYIKYQVIGDNNVAVPTHFFKVALFEVTPGKFELESYILPNAVIEDTVEISKFHVPLDAVERSAGLEIFARLDPKSIVKENGAK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords Endonuclease G, mitochondrial
publication title Oxidative Stress Impairs Cell Death by Repressing the Nuclease Activity of Mitochondrial Endonuclease G
pubmed doi rcsb
source organism Caenorhabditis elegans
total genus 72
structure length 238
sequence length 239
chains with identical sequence B, C, D
ec nomenclature ec 3.1.30.-:
pdb deposition date 2014-06-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01223 Endonuclease_NS DNA/RNA non-specific endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.570.10 Alpha Beta 3-Layer(aba) Sandwich Extracellular Endonuclease; Chain A Extracellular Endonuclease, subunit A 4qn0A00
3NKRA 3NKNA 2XRGA 4GTZA 5GKCA 3NKPA 2XR9A 3WAWA 5L0KA 5L0EA 2XGRA 3NKMA 4GTYA 5DLWA 3NKOA 1G8TA 1QAEA 5IJQA 3WAXA 2XH3A 4QH0A 1ZM8A 5HRTA 3WAVA 5LQQA 2O3BA 4ZGAA 3S5BA 5GKPA 4GTXA 4ZG9A 3OWVA 4E3YA 5KXAA 5INHA 4GTWA 4B56A 4QGOA 5LIAA 3WAYA 1QL0A 4ZG7A 5L0BA 3ISMA 1SMNA 3NKQA 4ZG6A 5IJSA 4A1NA 5DLVA 5DLTA 4QN0A
chains in the Genus database with same CATH superfamily
3NKRA 3NKNA 2XRGA 4GTZA 5GKCA 3NKPA 2XR9A 3WAWA 5L0KA 5L0EA 2XGRA 3NKMA 4GTYA 5DLWA 3NKOA 1G8TA 1QAEA 5IJQA 3WAXA 2XH3A 4QH0A 1ZM8A 5HRTA 3WAVA 5LQQA 2O3BA 4ZGAA 3S5BA 5GKPA 4GTXA 4ZG9A 3OWVA 4E3YA 5KXAA 5INHA 4GTWA 4B56A 4QGOA 5LIAA 3WAYA 1QL0A 4ZG7A 5L0BA 3ISMA 1SMNA 3NKQA 4ZG6A 5IJSA 4A1NA 5DLVA 5DLTA 4QN0A
chains in the Genus database with same CATH topology
3NKRA 3NKNA 2XRGA 4GTZA 5GKCA 3NKPA 2XR9A 3WAWA 5L0KA 5L0EA 2XGRA 3NKMA 4GTYA 5DLWA 3NKOA 1G8TA 1QAEA 5IJQA 3WAXA 2XH3A 4QH0A 1ZM8A 5HRTA 3WAVA 5LQQA 2O3BA 4ZGAA 3S5BA 5GKPA 4GTXA 4ZG9A 3OWVA 4E3YA 5KXAA 5INHA 4GTWA 4B56A 4QGOA 5LIAA 3WAYA 1QL0A 4ZG7A 5L0BA 3ISMA 1SMNA 3NKQA 4ZG6A 5IJSA 4A1NA 5DLVA 5DLTA 4QN0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3NKR A;  3NKN A;  2XRG A;  4GTZ A;  5GKC A;  3NKP A;  2XR9 A;  3WAW A;  5L0K A;  5L0E A;  2XGR A;  3NKM A;  4GTY A;  5DLW A;  3NKO A;  1G8T A;  1QAE A;  5IJQ A;  3WAX A;  2XH3 A;  4QH0 A;  1ZM8 A;  5HRT A;  3WAV A;  5LQQ A;  2O3B A;  4ZGA A;  3S5B A;  5GKP A;  4GTX A;  4ZG9 A;  3OWV A;  4E3Y A;  5KXA A;  5INH A;  4GTW A;  4B56 A;  4QGO A;  5LIA A;  3WAY A;  1QL0 A;  4ZG7 A;  5L0B A;  3ISM A;  1SMN A;  3NKQ A;  4ZG6 A;  5IJS A;  4A1N A;  5DLV A;  5DLT A;  4QN0 A; 
#chains in the Genus database with same CATH topology
 3NKR A;  3NKN A;  2XRG A;  4GTZ A;  5GKC A;  3NKP A;  2XR9 A;  3WAW A;  5L0K A;  5L0E A;  2XGR A;  3NKM A;  4GTY A;  5DLW A;  3NKO A;  1G8T A;  1QAE A;  5IJQ A;  3WAX A;  2XH3 A;  4QH0 A;  1ZM8 A;  5HRT A;  3WAV A;  5LQQ A;  2O3B A;  4ZGA A;  3S5B A;  5GKP A;  4GTX A;  4ZG9 A;  3OWV A;  4E3Y A;  5KXA A;  5INH A;  4GTW A;  4B56 A;  4QGO A;  5LIA A;  3WAY A;  1QL0 A;  4ZG7 A;  5L0B A;  3ISM A;  1SMN A;  3NKQ A;  4ZG6 A;  5IJS A;  4A1N A;  5DLV A;  5DLT A;  4QN0 A; 
#chains in the Genus database with same CATH homology
 3NKR A;  3NKN A;  2XRG A;  4GTZ A;  5GKC A;  3NKP A;  2XR9 A;  3WAW A;  5L0K A;  5L0E A;  2XGR A;  3NKM A;  4GTY A;  5DLW A;  3NKO A;  1G8T A;  1QAE A;  5IJQ A;  3WAX A;  2XH3 A;  4QH0 A;  1ZM8 A;  5HRT A;  3WAV A;  5LQQ A;  2O3B A;  4ZGA A;  3S5B A;  5GKP A;  4GTX A;  4ZG9 A;  3OWV A;  4E3Y A;  5KXA A;  5INH A;  4GTW A;  4B56 A;  4QGO A;  5LIA A;  3WAY A;  1QL0 A;  4ZG7 A;  5L0B A;  3ISM A;  1SMN A;  3NKQ A;  4ZG6 A;  5IJS A;  4A1N A;  5DLV A;  5DLT A;  4QN0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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