4V31A

Cereblon isoform 4 from magnetospirillum gryphiswaldense in complex with deoxyuridine
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
111
structure length
111
Chain Sequence
MVLAPGASIFRCRQCGQTISRRDWLLPMGGDHEHVVFNPAGMIFRVWCFSLAQGLRLIGAPSGEFSWFKGYDWTIALCGQCGSHLGWHYEGGSQPQTFFGLIKDRLAEGPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
molecule keywords CEREBLON ISOFORM 4
publication title Thalidomide Mimics Uridine Binding to an Aromatic Cage in Cereblon.
pubmed doi rcsb
source organism Magnetospirillum gryphiswaldense
total genus 23
structure length 111
sequence length 111
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2014-10-15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.150.20 Mainly Beta Beta Complex Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A Peptide methionine sulfoxide reductase. 4v31A00
3HCHA 3HCIA 5AMHA 3HCGA 3CXKA 3WX1A 2K8DA 3HCJA 3WX2A 4V31A 4CI2B 3E0MA 4TZUA 3MAOA 4TZ4C 4CI1B 2KV1A 3E0OA 4TZCA 4CI3B 3CEZA 4V2YA 4V30A 1L1DA 2KZNA 4V2ZA
chains in the Genus database with same CATH superfamily
1HXRA 2QFDA 3HCHA 3HCIA 5AMHA 3ZD7A 1H6QA 3HCGA 3CXKA 3NCUA 4A2XA 2HR9A 3OG8A 4AY2A 3WX1A 2RQAA 1FWQA 2YKGA 2KWBA 2K8DA 3HCJA 3WX2A 3EQTA 4V31A 2FU5A 3GA3A 4BPBA 2RMJA 3DJMA 3EBMA 3LRNA 4CI2B 2LOYA 3E0MA 4TZUA 3MAOA 3LRRA 3P3KA 4TZ4C 4CI1B 3ZD6A 5F9HA 2QFBA 2KV1A 3E0OA 4TZCA 4CI3B 1YZ1A 3FACA 3CEZA 4A2VA 1TXJA 1H7YA 2W4RA 2RQBA 2LVLA 4V2YA 4V30A 1L1DA 2KZNA 4V2ZA 5F98A 5F9FA 5E3HA
chains in the Genus database with same CATH topology
3HCHA 3HCIA 5AMHA 3HCGA 3CXKA 3WX1A 2K8DA 3HCJA 3WX2A 4V31A 4CI2B 3E0MA 4TZUA 3MAOA 4TZ4C 4CI1B 2KV1A 3E0OA 4TZCA 4CI3B 3CEZA 4V2YA 4V30A 1L1DA 2KZNA 4V2ZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HCH A;  3HCI A;  5AMH A;  3HCG A;  3CXK A;  3WX1 A;  2K8D A;  3HCJ A;  3WX2 A;  4V31 A;  4CI2 B;  3E0M A;  4TZU A;  3MAO A;  4TZ4 C;  4CI1 B;  2KV1 A;  3E0O A;  4TZC A;  4CI3 B;  3CEZ A;  4V2Y A;  4V30 A;  1L1D A;  2KZN A;  4V2Z A; 
#chains in the Genus database with same CATH topology
 1HXR A;  2QFD A;  3HCH A;  3HCI A;  5AMH A;  3ZD7 A;  1H6Q A;  3HCG A;  3CXK A;  3NCU A;  4A2X A;  2HR9 A;  3OG8 A;  4AY2 A;  3WX1 A;  2RQA A;  1FWQ A;  2YKG A;  2KWB A;  2K8D A;  3HCJ A;  3WX2 A;  3EQT A;  4V31 A;  2FU5 A;  3GA3 A;  4BPB A;  2RMJ A;  3DJM A;  3EBM A;  3LRN A;  4CI2 B;  2LOY A;  3E0M A;  4TZU A;  3MAO A;  3LRR A;  3P3K A;  4TZ4 C;  4CI1 B;  3ZD6 A;  5F9H A;  2QFB A;  2KV1 A;  3E0O A;  4TZC A;  4CI3 B;  1YZ1 A;  3FAC A;  3CEZ A;  4A2V A;  1TXJ A;  1H7Y A;  2W4R A;  2RQB A;  2LVL A;  4V2Y A;  4V30 A;  1L1D A;  2KZN A;  4V2Z A;  5F98 A;  5F9F A;  5E3H A; 
#chains in the Genus database with same CATH homology
 3HCH A;  3HCI A;  5AMH A;  3HCG A;  3CXK A;  3WX1 A;  2K8D A;  3HCJ A;  3WX2 A;  4V31 A;  4CI2 B;  3E0M A;  4TZU A;  3MAO A;  4TZ4 C;  4CI1 B;  2KV1 A;  3E0O A;  4TZC A;  4CI3 B;  3CEZ A;  4V2Y A;  4V30 A;  1L1D A;  2KZN A;  4V2Z A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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