4J7HA

Crystal structure of evaa, a 2,3-dehydratase in complex with dtdp-benzene and dtdp-rhamnose
Total Genus 141
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
141
Knots found
sequence length
458
structure length
446
Chain Sequence
AVRPRDHHDYADRIALSAATTDGVQMRTEDVRAWIAERRDANVFHVERIPFADLDQWWFEGVTGNLVHRSGRFFTIEGLHVIEHDGPHGDGPYREWQQPVIRQPEVGILGILAKEFDGVLHFLMQAKMEPGNPNLVQLSPTVQATRSNYNVKLIEYFAPPDPERVIVDVLQAEQGSWFFRKSNRNMIVETVDDVPLWDDFCWLTLGQIAELMHEDETINMNSRSVLSCLPYQDITPRALFSDVQLLSWFTNERSRHDVRVRRIPLADVCGWKQGAEEIEHEDGRYFKVLAVAVKKISWTQPLVESVDLGVVAFLVRKIDGVPHVLVQARVDGGFLDTVELAPTVQCTPLNYAHLPAEEAPPFLDLVQNAPRSRIRYEAIHSEEGGRFLGVRARYLVIDADEAIDPPPGYAWVTPAQLTALTRHGHYVNVEARTLLACINAAAAQPR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords EvaA 2,3-dehydratase
publication title Structure of EvaA: A Paradigm for Sugar 2,3-Dehydratases.
pubmed doi rcsb
source organism Amycolatopsis orientalis
molecule tags Biosynthetic protein
total genus 141
structure length 446
sequence length 458
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 4.2.1.159: dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose 2,3-dehydratase.
pdb deposition date 2013-02-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03559 Hexose_dehydrat NDP-hexose 2,3-dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.79.40 Alpha Beta Alpha-Beta Complex Nucleoside Triphosphate Pyrophosphohydrolase Nucleoside Triphosphate Pyrophosphohydrolase 4j7hA02
4J7GA 4J7HA
chains in the Genus database with same CATH superfamily
4KG3A 1G9QA 1VIQA 2YVNA 5ANVA 1VC8A 4S2WA 1VHZA 2DHOA 5ANUA 2JVBA 3ZR0A 5ISYA 5DPKA 2J8QA 3EEUA 1NQYA 4KG4A 4K6EA 3X0SA 1V8NA 1XSCA 4DYWA 1V8WA 5CFJA 4YPHA 3Q4IA 2GT4A 2W4EA 1Q27A 2B0VA 2DSDA 2A8TA 4JZUA 4S2XA 1V8IA 2DUKA 3H95A 3GG6A 4JZVA 1OW2A 2YVMA 3BM4A 3I7VA 1VK6A 2KDVA 3F13A 3FJYA 2AZWA 5ANWA 5GHIA 4S2VA 3SMDA 5DD4A 1U20A 1MQEA 1V8LA 4IJXA 3ACAA 4HVYA 1SOIA 1SZ3A 2VNPA 3GZ6A 5ANTA 5FSMA 3MCFA 1RRQA 2A8SA 3HHJA 2ICKA 2VNQA 1PUQA 1V8MA 3X0MA 1NFZA 1MR2A 2FMLA 3GRNA 5GHOA 4JZSA 1KTGA 3U53A 3X0IA 1MK1A 5GHPA 4JZTA 3X0QA 3SONA 2A8RA 3G0QA 3O61A 1F3YA 4J7HA 5GHJA 3QSJA 3X0JA 1IRYA 1JKNA 3X0PA 5DDGA 2XSQA 4NFWA 5HZXA 5BONA 2YYHA 3BHOA 2A6TA 1V8UA 1K26A 3FCMA 1Q54A 3A6TA 2QKMB 1RYAA 3RH7A 3EXQA 1NFSA 3Q93A 1NQZA 3BAPA 1VIUA 3DKUA 4ICKA 4ILQA 5ANSA 3O8SA 3X0LA 3MGMA 1V8SA 1VC9A 1KHZA 4NFXA 4S2YA 4MPOA 5FSOA 1PUSA 2I8TA 3Q91A 1PVFA 1V8VA 2DSCA 2GT2A 2B06A 3EF5A 4HFQA 5BS6A 5IW4A 2O5FA 3MDIA 5GHMA 3X0KA 3A6UA 3Q1PA 4J7GA 3I9XA 1HZTA 1V8RA 3E57A 1R67A 1MUTA 2R5WA 3P5TA 1TUMA 1PUNA 5C8LA 4C9XA 1SU2A 5CFIA 1Q33A 4YOQA 2B2KA 3COUA 3R03A 1PPVA 1VHGA 3O6ZA 2FKBA 5C7QA 2A8QA 1KT9A 2RRKA 2I8UA 1PPXA 1XSAA 2YVPA 1X84A 5FSNA 4KYXA 1HX3A 1I9AA 3L85A 1VRLA 1RRSA 5FSKA 2DSBA 2QJOA 5FSLA 3CNGA 1XSBA 1MP2A 3A6SA 2YVOA 5C7TA 5DEQA 3FSPA 5FSIA 3ID9A 1GA7A 3A6VA 3HYQA 1PPWA 3X0NA 2PNYA 3GZ5A 2Q9PA 5IW5A 2G73A 5GHQA 5I8UA 4ZG0A 5GHNA 2A8PA 2FVVA 3MDGA 3GWYA 3X0RA 1G0SA 1QVJA 2CL3A 3AC9A 3N9UA 2KDWA 1JRKA 4N1TA 2ICJA 2PQVA 3FFUA 1X83A 3F6AA 3WHWA 2QJTA 2CZRA 5LPGA 1V8YA 1VCDA 2GB5A 3DUPA 3I7UA 3OGAA 3X0OA 4KTBA 4YPRA 2G74A 3FK9A 3Q2SA 3N77A 3O69A 1MQWA 1V8TA 2O1CA 1SJYA 3GZ8A 3Q2TA 3KVHA 1X51A 2I6KA 4C9WA 3O52A 3P6YA 4V14A 3ZR1A 2O5WA 1K2EA 4N1UA 3J7Ye 3EESA 3SHDA
chains in the Genus database with same CATH topology
4KG3A 1G9QA 1VIQA 2YVNA 5ANVA 1VC8A 4S2WA 1VHZA 2DHOA 5ANUA 2JVBA 3ZR0A 5ISYA 5DPKA 2J8QA 3EEUA 1NQYA 4KG4A 4K6EA 3X0SA 1V8NA 1XSCA 4DYWA 1V8WA 5CFJA 4YPHA 3Q4IA 2GT4A 2W4EA 1Q27A 2B0VA 2DSDA 2A8TA 4JZUA 4S2XA 1V8IA 2DUKA 3H95A 3GG6A 4JZVA 1OW2A 2YVMA 3BM4A 3I7VA 1VK6A 2KDVA 3F13A 3FJYA 2AZWA 5ANWA 5GHIA 4S2VA 3SMDA 5DD4A 1U20A 1MQEA 1V8LA 4IJXA 3ACAA 4HVYA 1SOIA 1SZ3A 2VNPA 3GZ6A 5ANTA 5FSMA 3MCFA 1RRQA 2A8SA 3HHJA 2ICKA 2VNQA 1PUQA 1V8MA 3X0MA 1NFZA 1MR2A 2FMLA 3GRNA 5GHOA 4JZSA 1KTGA 3U53A 3X0IA 1MK1A 5GHPA 4JZTA 3X0QA 3SONA 2A8RA 3G0QA 3O61A 1F3YA 4J7HA 5GHJA 3QSJA 3X0JA 1IRYA 1JKNA 3X0PA 5DDGA 2XSQA 4NFWA 5HZXA 5BONA 2YYHA 3BHOA 2A6TA 1V8UA 1K26A 3FCMA 1Q54A 3A6TA 2QKMB 1RYAA 3RH7A 3EXQA 1NFSA 3Q93A 1NQZA 3BAPA 1VIUA 3DKUA 4ICKA 4ILQA 5ANSA 3O8SA 3X0LA 3MGMA 1V8SA 1VC9A 1KHZA 4NFXA 4S2YA 4MPOA 5FSOA 1PUSA 2I8TA 3Q91A 1PVFA 1V8VA 2DSCA 2GT2A 2B06A 3EF5A 4HFQA 5BS6A 5IW4A 2O5FA 3MDIA 5GHMA 3X0KA 3A6UA 3Q1PA 4J7GA 3I9XA 1HZTA 1V8RA 3E57A 1R67A 1MUTA 2R5WA 3P5TA 1TUMA 1PUNA 5C8LA 4C9XA 1SU2A 5CFIA 1Q33A 4YOQA 2B2KA 3COUA 3R03A 1PPVA 1VHGA 3O6ZA 2FKBA 5C7QA 2A8QA 1KT9A 2RRKA 2I8UA 1PPXA 1XSAA 2YVPA 1X84A 5FSNA 4KYXA 1HX3A 1I9AA 3L85A 1VRLA 1RRSA 5FSKA 2DSBA 2QJOA 5FSLA 3CNGA 1XSBA 1MP2A 3A6SA 2YVOA 5C7TA 5DEQA 3FSPA 5FSIA 3ID9A 1GA7A 3A6VA 3HYQA 1PPWA 3X0NA 2PNYA 3GZ5A 2Q9PA 5IW5A 2G73A 5GHQA 5I8UA 4ZG0A 5GHNA 2A8PA 2FVVA 3MDGA 3GWYA 3X0RA 1G0SA 1QVJA 2CL3A 3AC9A 3N9UA 2KDWA 1JRKA 4N1TA 2ICJA 2PQVA 3FFUA 1X83A 3F6AA 3WHWA 2QJTA 2CZRA 5LPGA 1V8YA 1VCDA 2GB5A 3DUPA 3I7UA 3OGAA 3X0OA 4KTBA 4YPRA 2G74A 3FK9A 3Q2SA 3N77A 3O69A 1MQWA 1V8TA 2O1CA 1SJYA 3GZ8A 3Q2TA 3KVHA 1X51A 2I6KA 4C9WA 3O52A 3P6YA 4V14A 3ZR1A 2O5WA 1K2EA 4N1UA 3J7Ye 3EESA 3SHDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4J7G A;  4J7H A; 
#chains in the Genus database with same CATH topology
 4KG3 A;  1G9Q A;  1VIQ A;  2YVN A;  5ANV A;  1VC8 A;  4S2W A;  1VHZ A;  2DHO A;  5ANU A;  2JVB A;  3ZR0 A;  5ISY A;  5DPK A;  2J8Q A;  3EEU A;  1NQY A;  4KG4 A;  4K6E A;  3X0S A;  1V8N A;  1XSC A;  4DYW A;  1V8W A;  5CFJ A;  4YPH A;  3Q4I A;  2GT4 A;  2W4E A;  1Q27 A;  2B0V A;  2DSD A;  2A8T A;  4JZU A;  4S2X A;  1V8I A;  2DUK A;  3H95 A;  3GG6 A;  4JZV A;  1OW2 A;  2YVM A;  3BM4 A;  3I7V A;  1VK6 A;  2KDV A;  3F13 A;  3FJY A;  2AZW A;  5ANW A;  5GHI A;  4S2V A;  3SMD A;  5DD4 A;  1U20 A;  1MQE A;  1V8L A;  4IJX A;  3ACA A;  4HVY A;  1SOI A;  1SZ3 A;  2VNP A;  3GZ6 A;  5ANT A;  5FSM A;  3MCF A;  1RRQ A;  2A8S A;  3HHJ A;  2ICK A;  2VNQ A;  1PUQ A;  1V8M A;  3X0M A;  1NFZ A;  1MR2 A;  2FML A;  3GRN A;  5GHO A;  4JZS A;  1KTG A;  3U53 A;  3X0I A;  1MK1 A;  5GHP A;  4JZT A;  3X0Q A;  3SON A;  2A8R A;  3G0Q A;  3O61 A;  1F3Y A;  4J7H A;  5GHJ A;  3QSJ A;  3X0J A;  1IRY A;  1JKN A;  3X0P A;  5DDG A;  2XSQ A;  4NFW A;  5HZX A;  5BON A;  2YYH A;  3BHO A;  2A6T A;  1V8U A;  1K26 A;  3FCM A;  1Q54 A;  3A6T A;  2QKM B;  1RYA A;  3RH7 A;  3EXQ A;  1NFS A;  3Q93 A;  1NQZ A;  3BAP A;  1VIU A;  3DKU A;  4ICK A;  4ILQ A;  5ANS A;  3O8S A;  3X0L A;  3MGM A;  1V8S A;  1VC9 A;  1KHZ A;  4NFX A;  4S2Y A;  4MPO A;  5FSO A;  1PUS A;  2I8T A;  3Q91 A;  1PVF A;  1V8V A;  2DSC A;  2GT2 A;  2B06 A;  3EF5 A;  4HFQ A;  5BS6 A;  5IW4 A;  2O5F A;  3MDI A;  5GHM A;  3X0K A;  3A6U A;  3Q1P A;  4J7G A;  3I9X A;  1HZT A;  1V8R A;  3E57 A;  1R67 A;  1MUT A;  2R5W A;  3P5T A;  1TUM A;  1PUN A;  5C8L A;  4C9X A;  1SU2 A;  5CFI A;  1Q33 A;  4YOQ A;  2B2K A;  3COU A;  3R03 A;  1PPV A;  1VHG A;  3O6Z A;  2FKB A;  5C7Q A;  2A8Q A;  1KT9 A;  2RRK A;  2I8U A;  1PPX A;  1XSA A;  2YVP A;  1X84 A;  5FSN A;  4KYX A;  1HX3 A;  1I9A A;  3L85 A;  1VRL A;  1RRS A;  5FSK A;  2DSB A;  2QJO A;  5FSL A;  3CNG A;  1XSB A;  1MP2 A;  3A6S A;  2YVO A;  5C7T A;  5DEQ A;  3FSP A;  5FSI A;  3ID9 A;  1GA7 A;  3A6V A;  3HYQ A;  1PPW A;  3X0N A;  2PNY A;  3GZ5 A;  2Q9P A;  5IW5 A;  2G73 A;  5GHQ A;  5I8U A;  4ZG0 A;  5GHN A;  2A8P A;  2FVV A;  3MDG A;  3GWY A;  3X0R A;  1G0S A;  1QVJ A;  2CL3 A;  3AC9 A;  3N9U A;  2KDW A;  1JRK A;  4N1T A;  2ICJ A;  2PQV A;  3FFU A;  1X83 A;  3F6A A;  3WHW A;  2QJT A;  2CZR A;  5LPG A;  1V8Y A;  1VCD A;  2GB5 A;  3DUP A;  3I7U A;  3OGA A;  3X0O A;  4KTB A;  4YPR A;  2G74 A;  3FK9 A;  3Q2S A;  3N77 A;  3O69 A;  1MQW A;  1V8T A;  2O1C A;  1SJY A;  3GZ8 A;  3Q2T A;  3KVH A;  1X51 A;  2I6K A;  4C9W A;  3O52 A;  3P6Y A;  4V14 A;  3ZR1 A;  2O5W A;  1K2E A;  4N1U A;  3J7Y e;  3EES A;  3SHD A; 
#chains in the Genus database with same CATH homology
 4KG3 A;  1G9Q A;  1VIQ A;  2YVN A;  5ANV A;  1VC8 A;  4S2W A;  1VHZ A;  2DHO A;  5ANU A;  2JVB A;  3ZR0 A;  5ISY A;  5DPK A;  2J8Q A;  3EEU A;  1NQY A;  4KG4 A;  4K6E A;  3X0S A;  1V8N A;  1XSC A;  4DYW A;  1V8W A;  5CFJ A;  4YPH A;  3Q4I A;  2GT4 A;  2W4E A;  1Q27 A;  2B0V A;  2DSD A;  2A8T A;  4JZU A;  4S2X A;  1V8I A;  2DUK A;  3H95 A;  3GG6 A;  4JZV A;  1OW2 A;  2YVM A;  3BM4 A;  3I7V A;  1VK6 A;  2KDV A;  3F13 A;  3FJY A;  2AZW A;  5ANW A;  5GHI A;  4S2V A;  3SMD A;  5DD4 A;  1U20 A;  1MQE A;  1V8L A;  4IJX A;  3ACA A;  4HVY A;  1SOI A;  1SZ3 A;  2VNP A;  3GZ6 A;  5ANT A;  5FSM A;  3MCF A;  1RRQ A;  2A8S A;  3HHJ A;  2ICK A;  2VNQ A;  1PUQ A;  1V8M A;  3X0M A;  1NFZ A;  1MR2 A;  2FML A;  3GRN A;  5GHO A;  4JZS A;  1KTG A;  3U53 A;  3X0I A;  1MK1 A;  5GHP A;  4JZT A;  3X0Q A;  3SON A;  2A8R A;  3G0Q A;  3O61 A;  1F3Y A;  4J7H A;  5GHJ A;  3QSJ A;  3X0J A;  1IRY A;  1JKN A;  3X0P A;  5DDG A;  2XSQ A;  4NFW A;  5HZX A;  5BON A;  2YYH A;  3BHO A;  2A6T A;  1V8U A;  1K26 A;  3FCM A;  1Q54 A;  3A6T A;  2QKM B;  1RYA A;  3RH7 A;  3EXQ A;  1NFS A;  3Q93 A;  1NQZ A;  3BAP A;  1VIU A;  3DKU A;  4ICK A;  4ILQ A;  5ANS A;  3O8S A;  3X0L A;  3MGM A;  1V8S A;  1VC9 A;  1KHZ A;  4NFX A;  4S2Y A;  4MPO A;  5FSO A;  1PUS A;  2I8T A;  3Q91 A;  1PVF A;  1V8V A;  2DSC A;  2GT2 A;  2B06 A;  3EF5 A;  4HFQ A;  5BS6 A;  5IW4 A;  2O5F A;  3MDI A;  5GHM A;  3X0K A;  3A6U A;  3Q1P A;  4J7G A;  3I9X A;  1HZT A;  1V8R A;  3E57 A;  1R67 A;  1MUT A;  2R5W A;  3P5T A;  1TUM A;  1PUN A;  5C8L A;  4C9X A;  1SU2 A;  5CFI A;  1Q33 A;  4YOQ A;  2B2K A;  3COU A;  3R03 A;  1PPV A;  1VHG A;  3O6Z A;  2FKB A;  5C7Q A;  2A8Q A;  1KT9 A;  2RRK A;  2I8U A;  1PPX A;  1XSA A;  2YVP A;  1X84 A;  5FSN A;  4KYX A;  1HX3 A;  1I9A A;  3L85 A;  1VRL A;  1RRS A;  5FSK A;  2DSB A;  2QJO A;  5FSL A;  3CNG A;  1XSB A;  1MP2 A;  3A6S A;  2YVO A;  5C7T A;  5DEQ A;  3FSP A;  5FSI A;  3ID9 A;  1GA7 A;  3A6V A;  3HYQ A;  1PPW A;  3X0N A;  2PNY A;  3GZ5 A;  2Q9P A;  5IW5 A;  2G73 A;  5GHQ A;  5I8U A;  4ZG0 A;  5GHN A;  2A8P A;  2FVV A;  3MDG A;  3GWY A;  3X0R A;  1G0S A;  1QVJ A;  2CL3 A;  3AC9 A;  3N9U A;  2KDW A;  1JRK A;  4N1T A;  2ICJ A;  2PQV A;  3FFU A;  1X83 A;  3F6A A;  3WHW A;  2QJT A;  2CZR A;  5LPG A;  1V8Y A;  1VCD A;  2GB5 A;  3DUP A;  3I7U A;  3OGA A;  3X0O A;  4KTB A;  4YPR A;  2G74 A;  3FK9 A;  3Q2S A;  3N77 A;  3O69 A;  1MQW A;  1V8T A;  2O1C A;  1SJY A;  3GZ8 A;  3Q2T A;  3KVH A;  1X51 A;  2I6K A;  4C9W A;  3O52 A;  3P6Y A;  4V14 A;  3ZR1 A;  2O5W A;  1K2E A;  4N1U A;  3J7Y e;  3EES A;  3SHD A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...