4KWFA

Crystal structure analysis of aldh2+aldib33
Total Genus 174
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
174
sequence length
494
structure length
494
Chain Sequence
AVPAPNQQPEVFCNQIFINNEWHDAVSRKTFPTVNPSTGEVICQVAEGDKEDVDKAVKAARAAFQLGSPWRRMDASHRGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYHGKTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQVAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYDEFVERSVARAKSRVVGNPFDSKTEQGPQVDETQFKKILGYINTGKQEGAKLLCGGGIAADRGYFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSTYGLAAAVFTKDLDKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTVKVPQKNS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Development of selective inhibitors for aldehyde dehydrogenases based on substituted indole-2,3-diones.
pubmed doi rcsb
molecule tags Oxidoreductase/inhibitor
source organism Homo sapiens
molecule keywords Aldehyde dehydrogenase, mitochondrial
total genus 174
structure length 494
sequence length 494
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 1.2.1.3: Aldehyde dehydrogenase (NAD(+)).
pdb deposition date 2013-05-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00171 Aldedh Aldehyde dehydrogenase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.309.10 Alpha Beta 3-Layer(aba) Sandwich Aldehyde Dehydrogenase; Chain A, domain 2 Aldehyde Dehydrogenase; Chain A, domain 2 4kwfA02
3.40.605.10 Alpha Beta 3-Layer(aba) Sandwich Aldehyde Dehydrogenase; Chain A, domain 1 Aldehyde Dehydrogenase; Chain A, domain 1 4kwfA01
1NZZA 4ZUKA 2EIIA 4WP7A 5A2DA 2XDRA 1BI9A 2VLEA 3JZ4A 4Q92A 5EK6A 1BXSA 4I8QA 1EUHA 2OPXA 3PQAA 2BHQA 2WMEA 2O2RA 1UXPA 4WPNA 3INJA 3N83A 4A0MA 4YWUA 1WNDA 4LEMA 2W8OA 3N82A 3RHDA 3V9LA 5EZ4A 1UZBA 5L13A 1NZXA 4GO0A 4I3WA 2IY6A 3RHLA 3QANA 3V4CA 2Y52A 4IDSA 2D4EA 2J5NA 4QETA 1O04A 3N80A 5DBVA 4KNAA 2JG7A 2ONMA 4JDCA 4KWFA 1O05A 4L1OA 4PXLB 4V3FA 2HG2A 5EUYA 2J6LA 4I3VA 1UXNA 4I3UA 5EXFA 3V9IA 2W8QA 2ONPA 1AD3A 1BPWA 4I26A 4QTOA 5ABMA 5EEBA 4NMKA 3K9DA 4X2QA 1UXTA 1NZWA 2ILUA 1A4SA 4ZVWA 2H5GA 3RHOA 2BJAA 2W8RA 4JZ6A 3MY7A 4H7NA 4E4GA 5L2NA 4PXLA 4GO3A 4IDMA 4ZULA 3VZ2A 1UXQA 1CW3A 5FHZA 2Y53A 3VZ3A 2WOXA 3ETFA 4L2OA 3RHMA 4QJEB 4IT9A 4OHTA 4LH3A 3R64A 4LH1A 4O5HA 2EHUA 3U4JA 5J7IA 3B4WA 1O00A 5KLMA 4NMJA 3R31A 2ONNA 4PXNA 5KLNA 1AG8A 3RHQA 4X0TA 5J6BA 5L2MA 3EFVA 4OE4A 4OE5A 2W8PA 5DIBA 5AC2A 5KLLA 5JRYA 1ZUMA 2ESDA 2IMPA 4O6RA 5EKCA 4H73A 3V9HA 4FQFA 3EK1A 4QJEA 4QYJA 4CBBA 1VLUA 5KJ5A 3V9GA 2EJLA 4I1WA 3IWKA 2O2QA 4YWEA 3RHRA 2QE0A 1O9JA 2BHPA 4PZ2A 3V9JA 1QI1A 3N81A 2EJ6A 5A2DC 4NEAA 3RHPA 4MPBA 3IWJA 3V9KA 3JU8A 4LGZA 1EZ0A 4NU9A 2WMEC 4IHIA 3RH9A 4K57A 4OE2A 4DALA 4GO2A 4NS3A 4ZZ7A 4ZXUA 4I3TA 5F2CA 2VROA 4KWGA 3VZ1A 1UXVA 4OGDA 4U3WA 3VZ0A 1UXRA 4V37A 4ZWLA 4YWVA 5KLOA 4X0UA 4I25A 4NPIA 4DNGA 4JBEA 4ZVYA 1O02A 3K2WA 4OUBA 5J78A 5KF0A 5L2OA 4ZVXA 4I2RA 1A4ZA 4ITAA 4V3FC 5DRUA 4I9BA 1T90A 4H80A 4I8PA 1KY8A 4CAZA 2EJDA 4LH0A 4WJ9A 3PRLA 4IYMA 4OE6A 4MPYA 1EYYA 1WNBA 3INLA 4WB9A 2EUHA 1O01A 5AC1A 4OU2A 2Y5DA 2O2PA 4QF6A 3SZBA 5AC0A 5KLKA 4GNZA 3ROSA 4X4LA 2Y51A 4GHKA 4E3XA 4C3SA 4FR8A 1QI6A 2BJKA 2EHQA 2EITA 2J40A 3RHHA 4ITBA 4LIHA 4QGKA 4F3XA 5A2DD 4LH2A 2ID2A 3RHJA 2EIWA 1O20A 4GO4A 3ZQAA 2W8NA 3RJLA 3I44A 5EYUA 3SZAA 1UXUA 3TY7A 4QN2A 3SZ9A 4I3XA 2ONOA
chains in the Genus database with same CATH superfamily
1NZZA 4ZUKA 2EIIA 4WP7A 5A2DA 2XDRA 1BI9A 2VLEA 3JZ4A 4Q92A 5EK6A 1BXSA 4I8QA 1EUHA 2OPXA 3PQAA 2BHQA 2WMEA 2O2RA 1UXPA 4WPNA 3INJA 3N83A 4A0MA 4YWUA 1WNDA 4LEMA 2W8OA 3N82A 3RHDA 3V9LA 5EZ4A 1UZBA 5L13A 1NZXA 4GO0A 4I3WA 2IY6A 3RHLA 3QANA 3V4CA 2Y52A 4IDSA 2D4EA 2J5NA 4QETA 1O04A 3N80A 5DBVA 4KNAA 2JG7A 2ONMA 4JDCA 4KWFA 1O05A 4L1OA 4PXLB 4V3FA 2HG2A 5EUYA 2J6LA 4I3VA 1UXNA 4I3UA 5EXFA 3V9IA 2W8QA 2ONPA 1AD3A 1BPWA 4I26A 4QTOA 5ABMA 5EEBA 4NMKA 3K9DA 4X2QA 1UXTA 1NZWA 2ILUA 1A4SA 4ZVWA 2H5GA 3RHOA 2BJAA 2W8RA 4JZ6A 3MY7A 4H7NA 4E4GA 5L2NA 4PXLA 4GO3A 4IDMA 4ZULA 3VZ2A 1UXQA 1CW3A 5FHZA 2Y53A 3VZ3A 2WOXA 3ETFA 4L2OA 3RHMA 4QJEB 4IT9A 4OHTA 4LH3A 3R64A 4LH1A 4O5HA 2EHUA 3U4JA 5J7IA 3B4WA 1O00A 5KLMA 4NMJA 3R31A 2ONNA 4PXNA 5KLNA 1AG8A 3RHQA 4X0TA 5J6BA 5L2MA 3EFVA 4OE4A 4OE5A 2W8PA 5DIBA 5AC2A 5KLLA 5JRYA 1ZUMA 2ESDA 2IMPA 4O6RA 5EKCA 4H73A 3V9HA 4FQFA 3EK1A 4QJEA 4QYJA 4CBBA 1VLUA 5KJ5A 3V9GA 2EJLA 4I1WA 3IWKA 2O2QA 4YWEA 3RHRA 2QE0A 1O9JA 2BHPA 4PZ2A 3V9JA 1QI1A 3N81A 2EJ6A 5A2DC 4NEAA 3RHPA 4MPBA 3IWJA 3V9KA 3JU8A 4LGZA 1EZ0A 4NU9A 2WMEC 4IHIA 3RH9A 4K57A 4OE2A 4DALA 4GO2A 4NS3A 4ZZ7A 4ZXUA 4I3TA 5F2CA 2VROA 4KWGA 3VZ1A 1UXVA 4OGDA 4U3WA 3VZ0A 1UXRA 4V37A 4ZWLA 4YWVA 5KLOA 4X0UA 4I25A 4NPIA 4DNGA 4JBEA 4ZVYA 1O02A 3K2WA 4OUBA 5J78A 5KF0A 5L2OA 4ZVXA 4I2RA 1A4ZA 4ITAA 4V3FC 5DRUA 4I9BA 1T90A 4H80A 4I8PA 1KY8A 4CAZA 2EJDA 4LH0A 4WJ9A 3PRLA 4IYMA 4OE6A 4MPYA 1EYYA 1WNBA 3INLA 4WB9A 2EUHA 1O01A 5AC1A 4OU2A 2Y5DA 2O2PA 4QF6A 3SZBA 5AC0A 5KLKA 4GNZA 3ROSA 4X4LA 2Y51A 4GHKA 4E3XA 4C3SA 4FR8A 1QI6A 2BJKA 2EHQA 2EITA 2J40A 3RHHA 4ITBA 4LIHA 4QGKA 4F3XA 5A2DD 4LH2A 2ID2A 3RHJA 2EIWA 1O20A 4GO4A 3ZQAA 2W8NA 3RJLA 3I44A 5EYUA 3SZAA 1UXUA 3TY7A 4QN2A 3SZ9A 4I3XA 2ONOA
chains in the Genus database with same CATH topology
1NZZA 4ZUKA 2EIIA 4WP7A 5A2DA 2XDRA 1BI9A 2VLEA 3JZ4A 4Q92A 5EK6A 1BXSA 4I8QA 1EUHA 2OPXA 3PQAA 2BHQA 2WMEA 2O2RA 1UXPA 4WPNA 3INJA 3N83A 4A0MA 4YWUA 1WNDA 4LEMA 2W8OA 3N82A 3RHDA 3V9LA 5EZ4A 1UZBA 5L13A 1NZXA 4GO0A 4I3WA 2IY6A 3RHLA 3QANA 3V4CA 2Y52A 4IDSA 2D4EA 2J5NA 4QETA 1O04A 3N80A 5DBVA 4KNAA 2JG7A 2ONMA 4JDCA 4KWFA 1O05A 4L1OA 4PXLB 4V3FA 2HG2A 5EUYA 2J6LA 4I3VA 1UXNA 4I3UA 5EXFA 3V9IA 2W8QA 2ONPA 1AD3A 1BPWA 4I26A 4QTOA 5ABMA 5EEBA 4NMKA 3K9DA 4X2QA 1UXTA 1NZWA 2ILUA 1A4SA 4ZVWA 2H5GA 3RHOA 2BJAA 2W8RA 4JZ6A 3MY7A 4H7NA 4E4GA 5L2NA 4PXLA 4GO3A 4IDMA 4ZULA 3VZ2A 1UXQA 1CW3A 5FHZA 2Y53A 3VZ3A 2WOXA 3ETFA 4L2OA 3RHMA 4QJEB 4IT9A 4OHTA 4LH3A 3R64A 4LH1A 4O5HA 2EHUA 3U4JA 5J7IA 3B4WA 1O00A 5KLMA 4NMJA 3R31A 2ONNA 4PXNA 5KLNA 1AG8A 3RHQA 4X0TA 5J6BA 5L2MA 3EFVA 4OE4A 4OE5A 2W8PA 5DIBA 5AC2A 5KLLA 5JRYA 1ZUMA 2ESDA 2IMPA 4O6RA 5EKCA 4H73A 3V9HA 4FQFA 3EK1A 4QJEA 4QYJA 4CBBA 1VLUA 5KJ5A 3V9GA 2EJLA 4I1WA 3IWKA 2O2QA 4YWEA 3RHRA 2QE0A 1O9JA 2BHPA 4PZ2A 3V9JA 1QI1A 3N81A 2EJ6A 5A2DC 4NEAA 3RHPA 4MPBA 3IWJA 3V9KA 3JU8A 4LGZA 1EZ0A 4NU9A 2WMEC 4IHIA 3RH9A 4K57A 4OE2A 4DALA 4GO2A 4NS3A 4ZZ7A 4ZXUA 4I3TA 5F2CA 2VROA 4KWGA 3VZ1A 1UXVA 4OGDA 4U3WA 3VZ0A 1UXRA 4V37A 4ZWLA 4YWVA 5KLOA 4X0UA 4I25A 4NPIA 4DNGA 4JBEA 4ZVYA 1O02A 3K2WA 4OUBA 5J78A 5KF0A 5L2OA 4ZVXA 4I2RA 1A4ZA 4ITAA 4V3FC 5DRUA 4I9BA 1T90A 4H80A 4I8PA 1KY8A 4CAZA 2EJDA 4LH0A 4WJ9A 3PRLA 4IYMA 4OE6A 4MPYA 1EYYA 1WNBA 3INLA 4WB9A 2EUHA 1O01A 5AC1A 4OU2A 2Y5DA 2O2PA 4QF6A 3SZBA 5AC0A 5KLKA 4GNZA 3ROSA 4X4LA 2Y51A 4GHKA 4E3XA 4C3SA 4FR8A 1QI6A 2BJKA 2EHQA 2EITA 2J40A 3RHHA 4ITBA 4LIHA 4QGKA 4F3XA 5A2DD 4LH2A 2ID2A 3RHJA 2EIWA 1O20A 4GO4A 3ZQAA 2W8NA 3RJLA 3I44A 5EYUA 3SZAA 1UXUA 3TY7A 4QN2A 3SZ9A 4I3XA 2ONOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NZZ A;  4ZUK A;  2EII A;  4WP7 A;  5A2D A;  2XDR A;  1BI9 A;  2VLE A;  3JZ4 A;  4Q92 A;  5EK6 A;  1BXS A;  4I8Q A;  1EUH A;  2OPX A;  3PQA A;  2BHQ A;  2WME A;  2O2R A;  1UXP A;  4WPN A;  3INJ A;  3N83 A;  4A0M A;  4YWU A;  1WND A;  4LEM A;  2W8O A;  3N82 A;  3RHD A;  3V9L A;  5EZ4 A;  1UZB A;  5L13 A;  1NZX A;  4GO0 A;  4I3W A;  2IY6 A;  3RHL A;  3QAN A;  3V4C A;  2Y52 A;  4IDS A;  2D4E A;  2J5N A;  4QET A;  1O04 A;  3N80 A;  5DBV A;  4KNA A;  2JG7 A;  2ONM A;  4JDC A;  4KWF A;  1O05 A;  4L1O A;  4PXL B;  4V3F A;  2HG2 A;  5EUY A;  2J6L A;  4I3V A;  1UXN A;  4I3U A;  5EXF A;  3V9I A;  2W8Q A;  2ONP A;  1AD3 A;  1BPW A;  4I26 A;  4QTO A;  5ABM A;  5EEB A;  4NMK A;  3K9D A;  4X2Q A;  1UXT A;  1NZW A;  2ILU A;  1A4S A;  4ZVW A;  2H5G A;  3RHO A;  2BJA A;  2W8R A;  4JZ6 A;  3MY7 A;  4H7N A;  4E4G A;  5L2N A;  4PXL A;  4GO3 A;  4IDM A;  4ZUL A;  3VZ2 A;  1UXQ A;  1CW3 A;  5FHZ A;  2Y53 A;  3VZ3 A;  2WOX A;  3ETF A;  4L2O A;  3RHM A;  4QJE B;  4IT9 A;  4OHT A;  4LH3 A;  3R64 A;  4LH1 A;  4O5H A;  2EHU A;  3U4J A;  5J7I A;  3B4W A;  1O00 A;  5KLM A;  4NMJ A;  3R31 A;  2ONN A;  4PXN A;  5KLN A;  1AG8 A;  3RHQ A;  4X0T A;  5J6B A;  5L2M A;  3EFV A;  4OE4 A;  4OE5 A;  2W8P A;  5DIB A;  5AC2 A;  5KLL A;  5JRY A;  1ZUM A;  2ESD A;  2IMP A;  4O6R A;  5EKC A;  4H73 A;  3V9H A;  4FQF A;  3EK1 A;  4QJE A;  4QYJ A;  4CBB A;  1VLU A;  5KJ5 A;  3V9G A;  2EJL A;  4I1W A;  3IWK A;  2O2Q A;  4YWE A;  3RHR A;  2QE0 A;  1O9J A;  2BHP A;  4PZ2 A;  3V9J A;  1QI1 A;  3N81 A;  2EJ6 A;  5A2D C;  4NEA A;  3RHP A;  4MPB A;  3IWJ A;  3V9K A;  3JU8 A;  4LGZ A;  1EZ0 A;  4NU9 A;  2WME C;  4IHI A;  3RH9 A;  4K57 A;  4OE2 A;  4DAL A;  4GO2 A;  4NS3 A;  4ZZ7 A;  4ZXU A;  4I3T A;  5F2C A;  2VRO A;  4KWG A;  3VZ1 A;  1UXV A;  4OGD A;  4U3W A;  3VZ0 A;  1UXR A;  4V37 A;  4ZWL A;  4YWV A;  5KLO A;  4X0U A;  4I25 A;  4NPI A;  4DNG A;  4JBE A;  4ZVY A;  1O02 A;  3K2W A;  4OUB A;  5J78 A;  5KF0 A;  5L2O A;  4ZVX A;  4I2R A;  1A4Z A;  4ITA A;  4V3F C;  5DRU A;  4I9B A;  1T90 A;  4H80 A;  4I8P A;  1KY8 A;  4CAZ A;  2EJD A;  4LH0 A;  4WJ9 A;  3PRL A;  4IYM A;  4OE6 A;  4MPY A;  1EYY A;  1WNB A;  3INL A;  4WB9 A;  2EUH A;  1O01 A;  5AC1 A;  4OU2 A;  2Y5D A;  2O2P A;  4QF6 A;  3SZB A;  5AC0 A;  5KLK A;  4GNZ A;  3ROS A;  4X4L A;  2Y51 A;  4GHK A;  4E3X A;  4C3S A;  4FR8 A;  1QI6 A;  2BJK A;  2EHQ A;  2EIT A;  2J40 A;  3RHH A;  4ITB A;  4LIH A;  4QGK A;  4F3X A;  5A2D D;  4LH2 A;  2ID2 A;  3RHJ A;  2EIW A;  1O20 A;  4GO4 A;  3ZQA A;  2W8N A;  3RJL A;  3I44 A;  5EYU A;  3SZA A;  1UXU A;  3TY7 A;  4QN2 A;  3SZ9 A;  4I3X A;  2ONO A; 
#chains in the Genus database with same CATH topology
 1NZZ A;  4ZUK A;  2EII A;  4WP7 A;  5A2D A;  2XDR A;  1BI9 A;  2VLE A;  3JZ4 A;  4Q92 A;  5EK6 A;  1BXS A;  4I8Q A;  1EUH A;  2OPX A;  3PQA A;  2BHQ A;  2WME A;  2O2R A;  1UXP A;  4WPN A;  3INJ A;  3N83 A;  4A0M A;  4YWU A;  1WND A;  4LEM A;  2W8O A;  3N82 A;  3RHD A;  3V9L A;  5EZ4 A;  1UZB A;  5L13 A;  1NZX A;  4GO0 A;  4I3W A;  2IY6 A;  3RHL A;  3QAN A;  3V4C A;  2Y52 A;  4IDS A;  2D4E A;  2J5N A;  4QET A;  1O04 A;  3N80 A;  5DBV A;  4KNA A;  2JG7 A;  2ONM A;  4JDC A;  4KWF A;  1O05 A;  4L1O A;  4PXL B;  4V3F A;  2HG2 A;  5EUY A;  2J6L A;  4I3V A;  1UXN A;  4I3U A;  5EXF A;  3V9I A;  2W8Q A;  2ONP A;  1AD3 A;  1BPW A;  4I26 A;  4QTO A;  5ABM A;  5EEB A;  4NMK A;  3K9D A;  4X2Q A;  1UXT A;  1NZW A;  2ILU A;  1A4S A;  4ZVW A;  2H5G A;  3RHO A;  2BJA A;  2W8R A;  4JZ6 A;  3MY7 A;  4H7N A;  4E4G A;  5L2N A;  4PXL A;  4GO3 A;  4IDM A;  4ZUL A;  3VZ2 A;  1UXQ A;  1CW3 A;  5FHZ A;  2Y53 A;  3VZ3 A;  2WOX A;  3ETF A;  4L2O A;  3RHM A;  4QJE B;  4IT9 A;  4OHT A;  4LH3 A;  3R64 A;  4LH1 A;  4O5H A;  2EHU A;  3U4J A;  5J7I A;  3B4W A;  1O00 A;  5KLM A;  4NMJ A;  3R31 A;  2ONN A;  4PXN A;  5KLN A;  1AG8 A;  3RHQ A;  4X0T A;  5J6B A;  5L2M A;  3EFV A;  4OE4 A;  4OE5 A;  2W8P A;  5DIB A;  5AC2 A;  5KLL A;  5JRY A;  1ZUM A;  2ESD A;  2IMP A;  4O6R A;  5EKC A;  4H73 A;  3V9H A;  4FQF A;  3EK1 A;  4QJE A;  4QYJ A;  4CBB A;  1VLU A;  5KJ5 A;  3V9G A;  2EJL A;  4I1W A;  3IWK A;  2O2Q A;  4YWE A;  3RHR A;  2QE0 A;  1O9J A;  2BHP A;  4PZ2 A;  3V9J A;  1QI1 A;  3N81 A;  2EJ6 A;  5A2D C;  4NEA A;  3RHP A;  4MPB A;  3IWJ A;  3V9K A;  3JU8 A;  4LGZ A;  1EZ0 A;  4NU9 A;  2WME C;  4IHI A;  3RH9 A;  4K57 A;  4OE2 A;  4DAL A;  4GO2 A;  4NS3 A;  4ZZ7 A;  4ZXU A;  4I3T A;  5F2C A;  2VRO A;  4KWG A;  3VZ1 A;  1UXV A;  4OGD A;  4U3W A;  3VZ0 A;  1UXR A;  4V37 A;  4ZWL A;  4YWV A;  5KLO A;  4X0U A;  4I25 A;  4NPI A;  4DNG A;  4JBE A;  4ZVY A;  1O02 A;  3K2W A;  4OUB A;  5J78 A;  5KF0 A;  5L2O A;  4ZVX A;  4I2R A;  1A4Z A;  4ITA A;  4V3F C;  5DRU A;  4I9B A;  1T90 A;  4H80 A;  4I8P A;  1KY8 A;  4CAZ A;  2EJD A;  4LH0 A;  4WJ9 A;  3PRL A;  4IYM A;  4OE6 A;  4MPY A;  1EYY A;  1WNB A;  3INL A;  4WB9 A;  2EUH A;  1O01 A;  5AC1 A;  4OU2 A;  2Y5D A;  2O2P A;  4QF6 A;  3SZB A;  5AC0 A;  5KLK A;  4GNZ A;  3ROS A;  4X4L A;  2Y51 A;  4GHK A;  4E3X A;  4C3S A;  4FR8 A;  1QI6 A;  2BJK A;  2EHQ A;  2EIT A;  2J40 A;  3RHH A;  4ITB A;  4LIH A;  4QGK A;  4F3X A;  5A2D D;  4LH2 A;  2ID2 A;  3RHJ A;  2EIW A;  1O20 A;  4GO4 A;  3ZQA A;  2W8N A;  3RJL A;  3I44 A;  5EYU A;  3SZA A;  1UXU A;  3TY7 A;  4QN2 A;  3SZ9 A;  4I3X A;  2ONO A; 
#chains in the Genus database with same CATH homology
 1NZZ A;  4ZUK A;  2EII A;  4WP7 A;  5A2D A;  2XDR A;  1BI9 A;  2VLE A;  3JZ4 A;  4Q92 A;  5EK6 A;  1BXS A;  4I8Q A;  1EUH A;  2OPX A;  3PQA A;  2BHQ A;  2WME A;  2O2R A;  1UXP A;  4WPN A;  3INJ A;  3N83 A;  4A0M A;  4YWU A;  1WND A;  4LEM A;  2W8O A;  3N82 A;  3RHD A;  3V9L A;  5EZ4 A;  1UZB A;  5L13 A;  1NZX A;  4GO0 A;  4I3W A;  2IY6 A;  3RHL A;  3QAN A;  3V4C A;  2Y52 A;  4IDS A;  2D4E A;  2J5N A;  4QET A;  1O04 A;  3N80 A;  5DBV A;  4KNA A;  2JG7 A;  2ONM A;  4JDC A;  4KWF A;  1O05 A;  4L1O A;  4PXL B;  4V3F A;  2HG2 A;  5EUY A;  2J6L A;  4I3V A;  1UXN A;  4I3U A;  5EXF A;  3V9I A;  2W8Q A;  2ONP A;  1AD3 A;  1BPW A;  4I26 A;  4QTO A;  5ABM A;  5EEB A;  4NMK A;  3K9D A;  4X2Q A;  1UXT A;  1NZW A;  2ILU A;  1A4S A;  4ZVW A;  2H5G A;  3RHO A;  2BJA A;  2W8R A;  4JZ6 A;  3MY7 A;  4H7N A;  4E4G A;  5L2N A;  4PXL A;  4GO3 A;  4IDM A;  4ZUL A;  3VZ2 A;  1UXQ A;  1CW3 A;  5FHZ A;  2Y53 A;  3VZ3 A;  2WOX A;  3ETF A;  4L2O A;  3RHM A;  4QJE B;  4IT9 A;  4OHT A;  4LH3 A;  3R64 A;  4LH1 A;  4O5H A;  2EHU A;  3U4J A;  5J7I A;  3B4W A;  1O00 A;  5KLM A;  4NMJ A;  3R31 A;  2ONN A;  4PXN A;  5KLN A;  1AG8 A;  3RHQ A;  4X0T A;  5J6B A;  5L2M A;  3EFV A;  4OE4 A;  4OE5 A;  2W8P A;  5DIB A;  5AC2 A;  5KLL A;  5JRY A;  1ZUM A;  2ESD A;  2IMP A;  4O6R A;  5EKC A;  4H73 A;  3V9H A;  4FQF A;  3EK1 A;  4QJE A;  4QYJ A;  4CBB A;  1VLU A;  5KJ5 A;  3V9G A;  2EJL A;  4I1W A;  3IWK A;  2O2Q A;  4YWE A;  3RHR A;  2QE0 A;  1O9J A;  2BHP A;  4PZ2 A;  3V9J A;  1QI1 A;  3N81 A;  2EJ6 A;  5A2D C;  4NEA A;  3RHP A;  4MPB A;  3IWJ A;  3V9K A;  3JU8 A;  4LGZ A;  1EZ0 A;  4NU9 A;  2WME C;  4IHI A;  3RH9 A;  4K57 A;  4OE2 A;  4DAL A;  4GO2 A;  4NS3 A;  4ZZ7 A;  4ZXU A;  4I3T A;  5F2C A;  2VRO A;  4KWG A;  3VZ1 A;  1UXV A;  4OGD A;  4U3W A;  3VZ0 A;  1UXR A;  4V37 A;  4ZWL A;  4YWV A;  5KLO A;  4X0U A;  4I25 A;  4NPI A;  4DNG A;  4JBE A;  4ZVY A;  1O02 A;  3K2W A;  4OUB A;  5J78 A;  5KF0 A;  5L2O A;  4ZVX A;  4I2R A;  1A4Z A;  4ITA A;  4V3F C;  5DRU A;  4I9B A;  1T90 A;  4H80 A;  4I8P A;  1KY8 A;  4CAZ A;  2EJD A;  4LH0 A;  4WJ9 A;  3PRL A;  4IYM A;  4OE6 A;  4MPY A;  1EYY A;  1WNB A;  3INL A;  4WB9 A;  2EUH A;  1O01 A;  5AC1 A;  4OU2 A;  2Y5D A;  2O2P A;  4QF6 A;  3SZB A;  5AC0 A;  5KLK A;  4GNZ A;  3ROS A;  4X4L A;  2Y51 A;  4GHK A;  4E3X A;  4C3S A;  4FR8 A;  1QI6 A;  2BJK A;  2EHQ A;  2EIT A;  2J40 A;  3RHH A;  4ITB A;  4LIH A;  4QGK A;  4F3X A;  5A2D D;  4LH2 A;  2ID2 A;  3RHJ A;  2EIW A;  1O20 A;  4GO4 A;  3ZQA A;  2W8N A;  3RJL A;  3I44 A;  5EYU A;  3SZA A;  1UXU A;  3TY7 A;  4QN2 A;  3SZ9 A;  4I3X A;  2ONO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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