4LLKA

Crystal structure of pde10a2 with fragment zt217
Total Genus 136
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
136
sequence length
330
structure length
330
Chain Sequence
AGTSICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGEETATWI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Identification and Optimization of PDE10A Inhibitors Using Fragment-Based Screening by Nanocalorimetry and X-ray Crystallography.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase
total genus 136
structure length 330
sequence length 330
chains with identical sequence B
ec nomenclature ec 3.1.4.17: 3',5'-cyclic-nucleotide phosphodiesterase.
pdb deposition date 2013-07-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00233 PDEase_I 3'5'-cyclic nucleotide phosphodiesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1300.10 Mainly Alpha Orthogonal Bundle Catalytic domain of cyclic nucleotide phosphodiesterase 4b2b 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain 4llkA00
1XOQA 2OVYA 5C2HA 1XN0A 2FM5A 2HD1A 1XM6A 1XOMA 4MSAA 3N3ZA 3G45A 1RKPA 1XLXA 3SNIA 3UUOA 5K9RA 4G2YA 1XORA 2OUNA 4Y87A 1Y2JA 2OUSA 4G2WA 4FCDA 4NW7A 3TGGA 3K3HA 1XM4B 4HF4A 3DYLA 2OUQA 4AJMA 1F0JA 1Y2HA 3G4LA 1TAZA 4G2LA 5AXQA 2H40A 4MSNA 5EDEA 3K3EA 4LLPA 3SHZA 5C28A 5I2RA 3HDZA 4FCBA 3G4IA 4HEUA 1XMYB 4D08A 4MRZA 1Z1LA 3HMVA 3G58A 3JWQA 3QI4A 5EDGA 5EDHA 2WEYA 1PTWA 3ECNA 4OEXA 4ZO5A 4TPPA 2Y0JA 4AJDA 3ITMA 3WYMA 4KP6A 4NPVA 1T9SA 3B2RA 5C29A 3DYSA 3GWTA 3HQZA 1ZKNA 4WZIA 3KKTA 3IBJA 3WYKA 1XMUA 3FRGA 4MRWA 4LM3A 3SL4A 3W5EA 3G4KA 5EDIA 3G4GA 1XOZA 3O0JA 1Y2BA 5B4KA 2OUYA 1RO9A 1RO6A 1XP0A 1Y2KA 1OYNA 3IAKA 5K32A 4Y2BA 1XOSA 4OEWA 4X0FA 1T9RA 3SHYA 3LY2A 5B4LA 3IADA 4BBXA 2OUVA 3BJCA 3HQWA 1UDTA 4TPMA 4JIBA 3V94A 3D3PA 4P1RA 4XY2A 4LLXA 3UI7A 4IA0A 3V93A 4MYQA 4MSHA 5B25A 2QYMA 4DFFA 2CHMA 4PHLA 2H44A 4YQHA 4GH6A 3V9BA 3DYNA 4LM0A 4LM4A 4WCUA 4OGBA 2O8HA 1ZKLA 1XONA 2R8QA 2YY2A 3DYQA 3QPPA 4E90A 1XLZA 3SL8A 4G2JA 4I15A 3QI3A 4MSEA 4PHWA 5AXPA 4AJFA 3HR1A 3SN7A 2OUPA 1Y2CA 3WS9A 5C1WA 5EDIB 4HTXA 4LKQA 4MVHA 3G3NA 3TVXA 3SNLA 4NPWA 2OUUA 4Y8CA 2OVVA 4QGEA 3LXGA 5EDEB 4PM0A 2OURA 1UDUA 3ITUA 1XOTA 3QPOA 1Q9MA 3DY8A 4LM2A 1TBBA 3O56A 3I8VA 3JWRA 4I9ZA 4P0NA 5EDGB 5K1IA 4LLJA 3SL6A 1RORA 5DH5A 3ECMA 1TBFA 1MKDA 3HC8A 4HTZA 3WI2A 3WS8A 1TB7A 1XM4A 4C1IA 4Y86A 4YS7A 4DDLA 1Y2DA 3JSWA 2PW3A 3O57A 4LM1A 5DH4A 4AJGA 3K4SA 3QPNA 1TB5A 4MSCA 4MS0A 1XMUB 4W1OA 2QYNA 4WN1A 3SL5A 3WD9A 3JSIA 5C2AA 4LLKA 1UHOA 1SOJA 1XMYA 2QYLA 1SO2A 3WYLA 2H42A 3SL3A 1Y2EA 3HQYA 4MUWA 3SIEA 4MD6A 4D09A 4AELA 2QYKA 5C2EA 2FM0A 3TGEA
chains in the Genus database with same CATH superfamily
1XOQA 2OVYA 5C2HA 1XN0A 2FM5A 2HD1A 1XM6A 1XOMA 4MSAA 3N3ZA 3G45A 1RKPA 1XLXA 3SNIA 3UUOA 5K9RA 4G2YA 1XORA 2OUNA 4Y87A 1Y2JA 2OUSA 4G2WA 4FCDA 4NW7A 3TGGA 3K3HA 1XM4B 4HF4A 3DYLA 2OUQA 4AJMA 1F0JA 1Y2HA 3G4LA 1TAZA 4G2LA 5AXQA 2H40A 4MSNA 5EDEA 3K3EA 4LLPA 3SHZA 5C28A 5I2RA 3HDZA 4FCBA 3G4IA 4HEUA 1XMYB 4D08A 4MRZA 1Z1LA 3HMVA 3G58A 3JWQA 3QI4A 5EDGA 5EDHA 2WEYA 1PTWA 3ECNA 4OEXA 4ZO5A 4TPPA 2Y0JA 4AJDA 3ITMA 3WYMA 4KP6A 4NPVA 1T9SA 3B2RA 5C29A 3DYSA 3GWTA 3HQZA 1ZKNA 4WZIA 3KKTA 3IBJA 3WYKA 1XMUA 3FRGA 4MRWA 4LM3A 3SL4A 3W5EA 3G4KA 5EDIA 3G4GA 1XOZA 3O0JA 1Y2BA 5B4KA 2OUYA 1RO9A 1RO6A 1XP0A 1Y2KA 1OYNA 3IAKA 5K32A 4Y2BA 1XOSA 4OEWA 4X0FA 1T9RA 3SHYA 3LY2A 5B4LA 3IADA 4BBXA 2OUVA 3BJCA 3HQWA 1UDTA 4TPMA 4JIBA 3V94A 3D3PA 4P1RA 4XY2A 4LLXA 3UI7A 4IA0A 3V93A 4MYQA 4MSHA 5B25A 2QYMA 4DFFA 2CHMA 4PHLA 2H44A 4YQHA 4GH6A 3V9BA 3DYNA 4LM0A 4LM4A 4WCUA 4OGBA 2O8HA 1ZKLA 1XONA 2R8QA 2YY2A 3DYQA 3QPPA 4E90A 1XLZA 3SL8A 4G2JA 4I15A 3QI3A 4MSEA 4PHWA 5AXPA 4AJFA 3HR1A 3SN7A 2OUPA 1Y2CA 3WS9A 5C1WA 5EDIB 4HTXA 4LKQA 4MVHA 3G3NA 3TVXA 3SNLA 4NPWA 2OUUA 4Y8CA 2OVVA 4QGEA 3LXGA 5EDEB 4PM0A 2OURA 1UDUA 3ITUA 1XOTA 3QPOA 1Q9MA 3DY8A 4LM2A 1TBBA 3O56A 3I8VA 3JWRA 4I9ZA 4P0NA 5EDGB 5K1IA 4LLJA 3SL6A 1RORA 5DH5A 3ECMA 1TBFA 1MKDA 3HC8A 4HTZA 3WI2A 3WS8A 1TB7A 1XM4A 4C1IA 4Y86A 4YS7A 4DDLA 1Y2DA 3JSWA 2PW3A 3O57A 4LM1A 5DH4A 4AJGA 3K4SA 3QPNA 1TB5A 4MSCA 4MS0A 1XMUB 4W1OA 2QYNA 4WN1A 3SL5A 3WD9A 3JSIA 5C2AA 4LLKA 1UHOA 1SOJA 1XMYA 2QYLA 1SO2A 3WYLA 2H42A 3SL3A 1Y2EA 3HQYA 4MUWA 3SIEA 4MD6A 4D09A 4AELA 2QYKA 5C2EA 2FM0A 3TGEA
chains in the Genus database with same CATH topology
1XOQA 2OVYA 5C2HA 1XN0A 2FM5A 2HD1A 1XM6A 1XOMA 4MSAA 3N3ZA 3G45A 1RKPA 1XLXA 3SNIA 3UUOA 5K9RA 4G2YA 1XORA 2OUNA 4Y87A 1Y2JA 2OUSA 4G2WA 4FCDA 4NW7A 3TGGA 3K3HA 1XM4B 4HF4A 3DYLA 2OUQA 4AJMA 1F0JA 1Y2HA 3G4LA 1TAZA 4G2LA 5AXQA 2H40A 4MSNA 5EDEA 3K3EA 4LLPA 3SHZA 5C28A 5I2RA 3HDZA 4FCBA 3G4IA 4HEUA 1XMYB 4D08A 4MRZA 1Z1LA 3HMVA 3G58A 3JWQA 3QI4A 5EDGA 5EDHA 2WEYA 1PTWA 3ECNA 4OEXA 4ZO5A 4TPPA 2Y0JA 4AJDA 3ITMA 3WYMA 4KP6A 4NPVA 1T9SA 3B2RA 5C29A 3DYSA 3GWTA 3HQZA 1ZKNA 4WZIA 3KKTA 3IBJA 3WYKA 1XMUA 3FRGA 4MRWA 4LM3A 3SL4A 3W5EA 3G4KA 5EDIA 3G4GA 1XOZA 3O0JA 1Y2BA 5B4KA 2OUYA 1RO9A 1RO6A 1XP0A 1Y2KA 1OYNA 3IAKA 5K32A 4Y2BA 1XOSA 4OEWA 4X0FA 1T9RA 3SHYA 3LY2A 5B4LA 3IADA 4BBXA 2OUVA 3BJCA 3HQWA 1UDTA 4TPMA 4JIBA 3V94A 3D3PA 4P1RA 4XY2A 4LLXA 3UI7A 4IA0A 3V93A 4MYQA 4MSHA 5B25A 2QYMA 4DFFA 2CHMA 4PHLA 2H44A 4YQHA 4GH6A 3V9BA 3DYNA 4LM0A 4LM4A 4WCUA 4OGBA 2O8HA 1ZKLA 1XONA 2R8QA 2YY2A 3DYQA 3QPPA 4E90A 1XLZA 3SL8A 4G2JA 4I15A 3QI3A 4MSEA 4PHWA 5AXPA 4AJFA 3HR1A 3SN7A 2OUPA 1Y2CA 3WS9A 5C1WA 5EDIB 4HTXA 4LKQA 4MVHA 3G3NA 3TVXA 3SNLA 4NPWA 2OUUA 4Y8CA 2OVVA 4QGEA 3LXGA 5EDEB 4PM0A 2OURA 1UDUA 3ITUA 1XOTA 3QPOA 1Q9MA 3DY8A 4LM2A 1TBBA 3O56A 3I8VA 3JWRA 4I9ZA 4P0NA 5EDGB 5K1IA 4LLJA 3SL6A 1RORA 5DH5A 3ECMA 1TBFA 1MKDA 3HC8A 4HTZA 3WI2A 3WS8A 1TB7A 1XM4A 4C1IA 4Y86A 4YS7A 4DDLA 1Y2DA 3JSWA 2PW3A 3O57A 4LM1A 5DH4A 4AJGA 3K4SA 3QPNA 1TB5A 4MSCA 4MS0A 1XMUB 4W1OA 2QYNA 4WN1A 3SL5A 3WD9A 3JSIA 5C2AA 4LLKA 1UHOA 1SOJA 1XMYA 2QYLA 1SO2A 3WYLA 2H42A 3SL3A 1Y2EA 3HQYA 4MUWA 3SIEA 4MD6A 4D09A 4AELA 2QYKA 5C2EA 2FM0A 3TGEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1XOQ A;  2OVY A;  5C2H A;  1XN0 A;  2FM5 A;  2HD1 A;  1XM6 A;  1XOM A;  4MSA A;  3N3Z A;  3G45 A;  1RKP A;  1XLX A;  3SNI A;  3UUO A;  5K9R A;  4G2Y A;  1XOR A;  2OUN A;  4Y87 A;  1Y2J A;  2OUS A;  4G2W A;  4FCD A;  4NW7 A;  3TGG A;  3K3H A;  1XM4 B;  4HF4 A;  3DYL A;  2OUQ A;  4AJM A;  1F0J A;  1Y2H A;  3G4L A;  1TAZ A;  4G2L A;  5AXQ A;  2H40 A;  4MSN A;  5EDE A;  3K3E A;  4LLP A;  3SHZ A;  5C28 A;  5I2R A;  3HDZ A;  4FCB A;  3G4I A;  4HEU A;  1XMY B;  4D08 A;  4MRZ A;  1Z1L A;  3HMV A;  3G58 A;  3JWQ A;  3QI4 A;  5EDG A;  5EDH A;  2WEY A;  1PTW A;  3ECN A;  4OEX A;  4ZO5 A;  4TPP A;  2Y0J A;  4AJD A;  3ITM A;  3WYM A;  4KP6 A;  4NPV A;  1T9S A;  3B2R A;  5C29 A;  3DYS A;  3GWT A;  3HQZ A;  1ZKN A;  4WZI A;  3KKT A;  3IBJ A;  3WYK A;  1XMU A;  3FRG A;  4MRW A;  4LM3 A;  3SL4 A;  3W5E A;  3G4K A;  5EDI A;  3G4G A;  1XOZ A;  3O0J A;  1Y2B A;  5B4K A;  2OUY A;  1RO9 A;  1RO6 A;  1XP0 A;  1Y2K A;  1OYN A;  3IAK A;  5K32 A;  4Y2B A;  1XOS A;  4OEW A;  4X0F A;  1T9R A;  3SHY A;  3LY2 A;  5B4L A;  3IAD A;  4BBX A;  2OUV A;  3BJC A;  3HQW A;  1UDT A;  4TPM A;  4JIB A;  3V94 A;  3D3P A;  4P1R A;  4XY2 A;  4LLX A;  3UI7 A;  4IA0 A;  3V93 A;  4MYQ A;  4MSH A;  5B25 A;  2QYM A;  4DFF A;  2CHM A;  4PHL A;  2H44 A;  4YQH A;  4GH6 A;  3V9B A;  3DYN A;  4LM0 A;  4LM4 A;  4WCU A;  4OGB A;  2O8H A;  1ZKL A;  1XON A;  2R8Q A;  2YY2 A;  3DYQ A;  3QPP A;  4E90 A;  1XLZ A;  3SL8 A;  4G2J A;  4I15 A;  3QI3 A;  4MSE A;  4PHW A;  5AXP A;  4AJF A;  3HR1 A;  3SN7 A;  2OUP A;  1Y2C A;  3WS9 A;  5C1W A;  5EDI B;  4HTX A;  4LKQ A;  4MVH A;  3G3N A;  3TVX A;  3SNL A;  4NPW A;  2OUU A;  4Y8C A;  2OVV A;  4QGE A;  3LXG A;  5EDE B;  4PM0 A;  2OUR A;  1UDU A;  3ITU A;  1XOT A;  3QPO A;  1Q9M A;  3DY8 A;  4LM2 A;  1TBB A;  3O56 A;  3I8V A;  3JWR A;  4I9Z A;  4P0N A;  5EDG B;  5K1I A;  4LLJ A;  3SL6 A;  1ROR A;  5DH5 A;  3ECM A;  1TBF A;  1MKD A;  3HC8 A;  4HTZ A;  3WI2 A;  3WS8 A;  1TB7 A;  1XM4 A;  4C1I A;  4Y86 A;  4YS7 A;  4DDL A;  1Y2D A;  3JSW A;  2PW3 A;  3O57 A;  4LM1 A;  5DH4 A;  4AJG A;  3K4S A;  3QPN A;  1TB5 A;  4MSC A;  4MS0 A;  1XMU B;  4W1O A;  2QYN A;  4WN1 A;  3SL5 A;  3WD9 A;  3JSI A;  5C2A A;  4LLK A;  1UHO A;  1SOJ A;  1XMY A;  2QYL A;  1SO2 A;  3WYL A;  2H42 A;  3SL3 A;  1Y2E A;  3HQY A;  4MUW A;  3SIE A;  4MD6 A;  4D09 A;  4AEL A;  2QYK A;  5C2E A;  2FM0 A;  3TGE A; 
#chains in the Genus database with same CATH topology
 1XOQ A;  2OVY A;  5C2H A;  1XN0 A;  2FM5 A;  2HD1 A;  1XM6 A;  1XOM A;  4MSA A;  3N3Z A;  3G45 A;  1RKP A;  1XLX A;  3SNI A;  3UUO A;  5K9R A;  4G2Y A;  1XOR A;  2OUN A;  4Y87 A;  1Y2J A;  2OUS A;  4G2W A;  4FCD A;  4NW7 A;  3TGG A;  3K3H A;  1XM4 B;  4HF4 A;  3DYL A;  2OUQ A;  4AJM A;  1F0J A;  1Y2H A;  3G4L A;  1TAZ A;  4G2L A;  5AXQ A;  2H40 A;  4MSN A;  5EDE A;  3K3E A;  4LLP A;  3SHZ A;  5C28 A;  5I2R A;  3HDZ A;  4FCB A;  3G4I A;  4HEU A;  1XMY B;  4D08 A;  4MRZ A;  1Z1L A;  3HMV A;  3G58 A;  3JWQ A;  3QI4 A;  5EDG A;  5EDH A;  2WEY A;  1PTW A;  3ECN A;  4OEX A;  4ZO5 A;  4TPP A;  2Y0J A;  4AJD A;  3ITM A;  3WYM A;  4KP6 A;  4NPV A;  1T9S A;  3B2R A;  5C29 A;  3DYS A;  3GWT A;  3HQZ A;  1ZKN A;  4WZI A;  3KKT A;  3IBJ A;  3WYK A;  1XMU A;  3FRG A;  4MRW A;  4LM3 A;  3SL4 A;  3W5E A;  3G4K A;  5EDI A;  3G4G A;  1XOZ A;  3O0J A;  1Y2B A;  5B4K A;  2OUY A;  1RO9 A;  1RO6 A;  1XP0 A;  1Y2K A;  1OYN A;  3IAK A;  5K32 A;  4Y2B A;  1XOS A;  4OEW A;  4X0F A;  1T9R A;  3SHY A;  3LY2 A;  5B4L A;  3IAD A;  4BBX A;  2OUV A;  3BJC A;  3HQW A;  1UDT A;  4TPM A;  4JIB A;  3V94 A;  3D3P A;  4P1R A;  4XY2 A;  4LLX A;  3UI7 A;  4IA0 A;  3V93 A;  4MYQ A;  4MSH A;  5B25 A;  2QYM A;  4DFF A;  2CHM A;  4PHL A;  2H44 A;  4YQH A;  4GH6 A;  3V9B A;  3DYN A;  4LM0 A;  4LM4 A;  4WCU A;  4OGB A;  2O8H A;  1ZKL A;  1XON A;  2R8Q A;  2YY2 A;  3DYQ A;  3QPP A;  4E90 A;  1XLZ A;  3SL8 A;  4G2J A;  4I15 A;  3QI3 A;  4MSE A;  4PHW A;  5AXP A;  4AJF A;  3HR1 A;  3SN7 A;  2OUP A;  1Y2C A;  3WS9 A;  5C1W A;  5EDI B;  4HTX A;  4LKQ A;  4MVH A;  3G3N A;  3TVX A;  3SNL A;  4NPW A;  2OUU A;  4Y8C A;  2OVV A;  4QGE A;  3LXG A;  5EDE B;  4PM0 A;  2OUR A;  1UDU A;  3ITU A;  1XOT A;  3QPO A;  1Q9M A;  3DY8 A;  4LM2 A;  1TBB A;  3O56 A;  3I8V A;  3JWR A;  4I9Z A;  4P0N A;  5EDG B;  5K1I A;  4LLJ A;  3SL6 A;  1ROR A;  5DH5 A;  3ECM A;  1TBF A;  1MKD A;  3HC8 A;  4HTZ A;  3WI2 A;  3WS8 A;  1TB7 A;  1XM4 A;  4C1I A;  4Y86 A;  4YS7 A;  4DDL A;  1Y2D A;  3JSW A;  2PW3 A;  3O57 A;  4LM1 A;  5DH4 A;  4AJG A;  3K4S A;  3QPN A;  1TB5 A;  4MSC A;  4MS0 A;  1XMU B;  4W1O A;  2QYN A;  4WN1 A;  3SL5 A;  3WD9 A;  3JSI A;  5C2A A;  4LLK A;  1UHO A;  1SOJ A;  1XMY A;  2QYL A;  1SO2 A;  3WYL A;  2H42 A;  3SL3 A;  1Y2E A;  3HQY A;  4MUW A;  3SIE A;  4MD6 A;  4D09 A;  4AEL A;  2QYK A;  5C2E A;  2FM0 A;  3TGE A; 
#chains in the Genus database with same CATH homology
 1XOQ A;  2OVY A;  5C2H A;  1XN0 A;  2FM5 A;  2HD1 A;  1XM6 A;  1XOM A;  4MSA A;  3N3Z A;  3G45 A;  1RKP A;  1XLX A;  3SNI A;  3UUO A;  5K9R A;  4G2Y A;  1XOR A;  2OUN A;  4Y87 A;  1Y2J A;  2OUS A;  4G2W A;  4FCD A;  4NW7 A;  3TGG A;  3K3H A;  1XM4 B;  4HF4 A;  3DYL A;  2OUQ A;  4AJM A;  1F0J A;  1Y2H A;  3G4L A;  1TAZ A;  4G2L A;  5AXQ A;  2H40 A;  4MSN A;  5EDE A;  3K3E A;  4LLP A;  3SHZ A;  5C28 A;  5I2R A;  3HDZ A;  4FCB A;  3G4I A;  4HEU A;  1XMY B;  4D08 A;  4MRZ A;  1Z1L A;  3HMV A;  3G58 A;  3JWQ A;  3QI4 A;  5EDG A;  5EDH A;  2WEY A;  1PTW A;  3ECN A;  4OEX A;  4ZO5 A;  4TPP A;  2Y0J A;  4AJD A;  3ITM A;  3WYM A;  4KP6 A;  4NPV A;  1T9S A;  3B2R A;  5C29 A;  3DYS A;  3GWT A;  3HQZ A;  1ZKN A;  4WZI A;  3KKT A;  3IBJ A;  3WYK A;  1XMU A;  3FRG A;  4MRW A;  4LM3 A;  3SL4 A;  3W5E A;  3G4K A;  5EDI A;  3G4G A;  1XOZ A;  3O0J A;  1Y2B A;  5B4K A;  2OUY A;  1RO9 A;  1RO6 A;  1XP0 A;  1Y2K A;  1OYN A;  3IAK A;  5K32 A;  4Y2B A;  1XOS A;  4OEW A;  4X0F A;  1T9R A;  3SHY A;  3LY2 A;  5B4L A;  3IAD A;  4BBX A;  2OUV A;  3BJC A;  3HQW A;  1UDT A;  4TPM A;  4JIB A;  3V94 A;  3D3P A;  4P1R A;  4XY2 A;  4LLX A;  3UI7 A;  4IA0 A;  3V93 A;  4MYQ A;  4MSH A;  5B25 A;  2QYM A;  4DFF A;  2CHM A;  4PHL A;  2H44 A;  4YQH A;  4GH6 A;  3V9B A;  3DYN A;  4LM0 A;  4LM4 A;  4WCU A;  4OGB A;  2O8H A;  1ZKL A;  1XON A;  2R8Q A;  2YY2 A;  3DYQ A;  3QPP A;  4E90 A;  1XLZ A;  3SL8 A;  4G2J A;  4I15 A;  3QI3 A;  4MSE A;  4PHW A;  5AXP A;  4AJF A;  3HR1 A;  3SN7 A;  2OUP A;  1Y2C A;  3WS9 A;  5C1W A;  5EDI B;  4HTX A;  4LKQ A;  4MVH A;  3G3N A;  3TVX A;  3SNL A;  4NPW A;  2OUU A;  4Y8C A;  2OVV A;  4QGE A;  3LXG A;  5EDE B;  4PM0 A;  2OUR A;  1UDU A;  3ITU A;  1XOT A;  3QPO A;  1Q9M A;  3DY8 A;  4LM2 A;  1TBB A;  3O56 A;  3I8V A;  3JWR A;  4I9Z A;  4P0N A;  5EDG B;  5K1I A;  4LLJ A;  3SL6 A;  1ROR A;  5DH5 A;  3ECM A;  1TBF A;  1MKD A;  3HC8 A;  4HTZ A;  3WI2 A;  3WS8 A;  1TB7 A;  1XM4 A;  4C1I A;  4Y86 A;  4YS7 A;  4DDL A;  1Y2D A;  3JSW A;  2PW3 A;  3O57 A;  4LM1 A;  5DH4 A;  4AJG A;  3K4S A;  3QPN A;  1TB5 A;  4MSC A;  4MS0 A;  1XMU B;  4W1O A;  2QYN A;  4WN1 A;  3SL5 A;  3WD9 A;  3JSI A;  5C2A A;  4LLK A;  1UHO A;  1SOJ A;  1XMY A;  2QYL A;  1SO2 A;  3WYL A;  2H42 A;  3SL3 A;  1Y2E A;  3HQY A;  4MUW A;  3SIE A;  4MD6 A;  4D09 A;  4AEL A;  2QYK A;  5C2E A;  2FM0 A;  3TGE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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