The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
135
|
Knots found |
|
sequence length |
386
|
structure length |
386
|
Chain Sequence |
EQFLFSSESVCSGHPDKLCDQISDAILDACLEQDPESFVACETCTKTGFIMVFGEITTKANVNYERVVRETVKEIGYDSEEKGLDYKTMDVIIKLEQQSNQIAGCVHVDKNVEDIGAGDQGMMFGYATNETKELMPLTHVLATSITRELDYIRMKGVSSRVGWLRPDGKAQVTVEYNCKHGVLIPKRIHTILVSVQHDENIENEEIREFVLENVIKKVCPSDLMDKETRILINPSGRFTIGGPAADAGLTGRKIIVDTYGGWGAHGGGAFSGKDATKVDRSGAYMARLVAKSIVFSGLCSRCLVQVSYGIGIARPLSLYINTFGTAKDGYNDTKLLEIVNKVFDFRPGILIKQLNLKSPIFKKTSSGGHFGRSEKEFLWEKPIILQ
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| molecule tags |
Transferase
|
| molecule keywords |
S-adenosylmethionine synthase
|
| publication title |
Crystal structure of a putative S-adenosylmethionine synthetase from Cryptosporidium hominis in complex with S-adenosyl-methionine
rcsb |
| source organism |
Cryptosporidium hominis
|
| total genus |
135
|
| structure length |
386
|
| sequence length |
386
|
| other databases |
 KnotProt 2.0: K +31
|
| ec nomenclature |
ec
2.5.1.6: Methionine adenosyltransferase. |
| pdb deposition date | 2014-01-10 |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Alpha Beta | 2-Layer Sandwich | GMP Synthetase; Chain A, domain 3 | GMP Synthetase; Chain A, domain 3 | ||
| Alpha Beta | 2-Layer Sandwich | GMP Synthetase; Chain A, domain 3 | GMP Synthetase; Chain A, domain 3 | ||
| Alpha Beta | 2-Layer Sandwich | GMP Synthetase; Chain A, domain 3 | GMP Synthetase; Chain A, domain 3 |
#chains in the Genus database with same CATH superfamily 4L4Q A; 3TDE A; 4LE5 A; 2YWC A; 4HPV A; 2YWB A; 3S82 A; 5T8T A; 5A1G A; 4ODJ A; 1FUG A; 1O92 A; 4L7I A; 4NDN A; 2P02 A; 4WS9 A; 3A4I A; 1XRA A; 1GPM A; 4L2Z A; 3RV2 A; 5H9U A; 4KTT A; 1QM4 A; 3SO4 A; 3UOW A; 1XRC A; 3TQI A; 1MXB A; 1P7L A; 5A1I A; 1MXA A; 1O93 A; 2OBV A; 5T8S A; 1O90 A; 4K0B A; 1XRB A; 4KTV A; 2DPL A; 1MXC A; 3IML A; 5A19 A; 1RG9 A; 1O9T A; #chains in the Genus database with same CATH topology 5LMN C; 5T8T A; 1NY8 A; 4OX9 C; 1HH2 P; 4TPS B; 2QVY X; 4JI6 C; 4L2Z A; 4FUT A; 4R1L A; 1VEH A; 5DV9 A; 3LUS A; 1ZB8 A; 1IBK C; 1XRC A; 4DR7 C; 3UEB A; 4PUI A; 2WD9 A; 4JYA C; 2E8E A; 4R1M A; 3CW8 X; 3NPD A; 5K85 A; 4DG8 A; 4X65 C; 1V25 A; 2KZF A; 2P02 A; 1N32 C; 4WS9 A; 3DAY A; 5BUR A; 3FCC A; 1N34 C; 4KTT A; 3FCE A; 3UOW A; 4LF8 C; 5BSR A; 5T8S A; 1O90 A; 3UX2 A; 4RLF A; 4DV4 C; 1USP B; 1L2F A; 2Y4O A; 4DR1 C; 5BSU A; 4D4I A; 4LF4 C; 4G37 A; 5FLX D; 4DV1 C; 4LFA C; 2UU9 C; 4DR3 C; 1UKK A; 1K0R A; 2WP0 C; 4AQY C; 4DUZ C; 2ZZM A; 3IML A; 1XNR C; 1T5H X; 1M6X A; 3A9U A; 4ODJ A; 2Z51 A; 3DLP X; 4L7I A; 5BSM A; 3PBK A; 3VNR A; 2D1Q A; 4DCT A; 2ATW A; 5H9U A; 4LF9 C; 1XMO C; 3J81 D; 4LF7 C; 4PRO C; 4GXQ A; 4K0B A; 1V60 A; 1WF3 A; 1FLO A; 4OXI A; 1XS3 A; 4JI8 C; 3E7W A; 1AMU A; 1RG9 A; 4IZ6 A; 5AE1 A; 5IFI A; 2XR1 A; 1IBL C; 4JI2 C; 2NCL A; 1VLA A; 3A25 A; 4X66 C; 3A4I A; 3GR0 A; 2UUA C; 1I94 C; 3L95 X; 4JI7 C; 3R9W A; 1V26 A; 5KYT A; 1MXB A; 1P7L A; 2CU6 A; 2P20 A; 4RLQ A; 2OBV A; 4X64 C; 5AE2 A; 4D57 A; 4DV7 C; 5AE3 A; 3N2Q A; 2P2Q A; 3TR3 A; 5CZV A; 3CQ1 A; 3PRO C; 2MMA B; 1ULT A; 4RM3 A; 3RV2 A; 3TQI A; 4DCS A; 4PUG A; 3IEU A; 4KTV A; 4BC9 A; 1JOS A; 1P4E A; 4FUQ A; 1MXC A; 2PN2 A; 1O9T A; 2P2F A; 3T1H C; 1PG3 A; 1FUG A; 4RM2 A; 3R44 A; 2DHM A; 4RVN A; 2E5L C; 2ASB A; 3G7S A; 4LF5 C; 2KZ0 A; 1PU1 A; 4OYC A; 1YJ7 A; 2E8C A; 1P4E C; 2E7G A; 4B3M C; 4RVO A; 4LFC C; 3EQ6 A; 4BC7 A; 5BUS A; 3I07 A; 2OO4 A; 1QWI A; 4NDN A; 2KDN A; 3CQ3 A; 4I9G A; 2DYJ A; 4LF6 C; 4ZLP A; 1WH9 A; 2QVZ X; 5JRH A; 1ML8 A; 4D4G A; 5IWA C; 3LGX A; 4BSZ A; 3EER A; 2Y4N A; 2D28 C; 2MCQ A; 4YHH C; 1N36 C; 4HPV A; 4GKK C; 5A1G A; 2V7B A; 2D27 A; 3CQ2 A; 2BJO A; 1GPM A; 2E0G A; 3DHV A; 3RG2 A; 4NXN C; 1RY2 A; 5BUQ A; 1LQL A; 1IB8 A; 4JV5 C; 2HHH C; 4JI1 C; 2DPL A; 3OTO C; 2YWB A; 4R0M A; 3TDE A; 4MH4 A; 1XHJ A; 4YY3 C; 3ETC A; 4PZP A; 4B3R C; 1T5D X; 1M6X C; 3H2T A; 4B3T C; 2Y27 A; 1FJG C; 4GS5 A; 3ETO A; 3C5E A; 2UXB C; 2VQE C; 3SO4 A; 3N54 B; 5BST A; 2UXC C; 1WCJ A; 5BSW A; 4DV2 C; 1MXA A; 3K6R A; 3A9V A; 5BR8 C; 2MM9 A; 5K8F A; 3CJE A; 5KEI A; 2ONF A; 3LAX A; 5IT9 D; 5ADZ A; 3KXW A; 2QL8 A; 4WV3 A; 2UUB C; 3AF5 A; 4K0K C; 3LNV A; 2M5H A; 2P2B A; 3IPL A; 1N2F A; 1NYE A; 3GKU A; 2HJG A; 4BBY A; 4U5Y D; 2BH1 X; 3E7X A; 4PHT A; 1IBM C; 2ZM6 C; 2YWC A; 1HNZ C; 2JNV A; 3S82 A; 1HNX C; 4KHP C; 1MKY A; 4G1I A; 4X62 C; 2YCB A; 5BSV A; 1XMQ C; 1XRA A; 4D56 A; 1N33 C; 2M5O A; 5E7Q A; 3VNQ A; 4GKJ C; 3IEV A; 4JI5 C; 4DV0 C; 4B3S C; 3TUF A; 1HR0 C; 3UZ0 A; 3B7W A; 5A19 A; 4RMN A; 2E8F A; 2QW0 X; 4DCV A; 5LMU C; 2PT7 G; 4DR2 C; 1PG4 A; 2JMP A; 3I08 A; 3CW9 A; 3O2E A; 4DV3 C; 1TH5 A; 4JM1 A; 4DG9 A; 4NOZ A; 3LNO A; 1BA3 A; 1USP A; 1UWD A; 5GTD A; 3JAM D; 3J80 D; 2D1R A; 1PA4 A; 5KYV A; 4BCA A; 5CZX A; 1ZB9 A; 2EGT A; 1LCI A; 4EAT A; 5A2Q D; 4MTN A; 3A26 A; 1O93 A; 4DV5 C; 1KKG A; 4DR6 C; 2AYA A; 4ZJZ A; 4ISB A; 1MD9 A; 1MDF A; 4DV6 C; 1O92 A; 4JI4 C; 3NYR A; 3AF6 A; 3NYQ A; 3PES A; 2D7V A; 3GPC A; 3GR1 A; 4IR7 A; 2UXD C; 4G36 A; 2F4V C; 2UUC C; 4DCU A; 5LCI A; 2PRO A; 5A1I A; 2VQF C; 2ZZN A; 4DR4 C; 4JI0 C; 1XRB A; 1MDB A; 4XX2 A; 4I9F A; 2QVX X; 4L4Q A; 4LE5 A; 3R9X A; 2D1T A; 4FTF A; 1J5E C; 4GXR A; 3UX3 A; 4DUY C; 3NI2 A; 2OPL A; 4NXM C; 2P2J A; 3AY0 A; 3VNS A; 3T1Y C; 2OPL B; 1QM4 A; 1XNQ C; 1EGA A; 4DR5 C; 2VSQ A; 2YX1 A; 4JI3 C; 2CY1 A; 2VZE A; 2D1S A; 4LFB C; 2CXC A; 3L8C A; 1HNW C; 4PUH A; 2P2M A; #chains in the Genus database with same CATH homology 5LMN C; 5T8T A; 4OX9 C; 1HH2 P; 4TPS B; 2QVY X; 4JI6 C; 4L2Z A; 4FUT A; 4R1L A; 5DV9 A; 3LUS A; 1ZB8 A; 1IBK C; 1XRC A; 4DR7 C; 2WD9 A; 4JYA C; 2E8E A; 4R1M A; 3CW8 X; 3NPD A; 5K85 A; 4DG8 A; 4X65 C; 1V25 A; 2KZF A; 2P02 A; 1N32 C; 4WS9 A; 3DAY A; 5BUR A; 3FCC A; 1N34 C; 4KTT A; 3FCE A; 3UOW A; 4LF8 C; 5BSR A; 5T8S A; 1O90 A; 4RLF A; 4DV4 C; 1USP B; 1L2F A; 2Y4O A; 4DR1 C; 5BSU A; 4D4I A; 4LF4 C; 4G37 A; 5FLX D; 4DV1 C; 4LFA C; 2UU9 C; 4DR3 C; 1UKK A; 1K0R A; 2WP0 C; 4AQY C; 4DUZ C; 3IML A; 1XNR C; 1T5H X; 3A9U A; 4ODJ A; 3DLP X; 4L7I A; 5BSM A; 3PBK A; 3VNR A; 2D1Q A; 4DCT A; 2ATW A; 5H9U A; 4LF9 C; 1XMO C; 3J81 D; 4LF7 C; 4PRO C; 4GXQ A; 4K0B A; 1WF3 A; 4OXI A; 4JI8 C; 3E7W A; 1AMU A; 1RG9 A; 4IZ6 A; 5AE1 A; 5IFI A; 2XR1 A; 1IBL C; 4JI2 C; 1VLA A; 4X66 C; 3A4I A; 3GR0 A; 2UUA C; 1I94 C; 3L95 X; 4JI7 C; 3R9W A; 1V26 A; 5KYT A; 1MXB A; 1P7L A; 2P20 A; 4RLQ A; 2OBV A; 4X64 C; 5AE2 A; 4D57 A; 4DV7 C; 5AE3 A; 3N2Q A; 2P2Q A; 5CZV A; 3PRO C; 1ULT A; 4RM3 A; 3RV2 A; 3TQI A; 4DCS A; 3IEU A; 4KTV A; 4BC9 A; 1JOS A; 4FUQ A; 1MXC A; 2PN2 A; 1O9T A; 2P2F A; 3T1H C; 1PG3 A; 1FUG A; 4RM2 A; 3R44 A; 4RVN A; 2E5L C; 2ASB A; 3G7S A; 4LF5 C; 4OYC A; 1YJ7 A; 2E8C A; 2E7G A; 4B3M C; 4RVO A; 4LFC C; 3EQ6 A; 4BC7 A; 5BUS A; 3I07 A; 2OO4 A; 1QWI A; 4NDN A; 4I9G A; 2DYJ A; 4LF6 C; 4ZLP A; 1WH9 A; 2QVZ X; 5JRH A; 1ML8 A; 4D4G A; 5IWA C; 3LGX A; 4BSZ A; 3EER A; 2Y4N A; 2D28 C; 4YHH C; 1N36 C; 4HPV A; 4GKK C; 5A1G A; 2V7B A; 2D27 A; 2BJO A; 1GPM A; 2E0G A; 3DHV A; 3RG2 A; 4NXN C; 1RY2 A; 5BUQ A; 1LQL A; 4JV5 C; 2HHH C; 4JI1 C; 2DPL A; 3OTO C; 2YWB A; 4R0M A; 3TDE A; 4MH4 A; 4YY3 C; 3ETC A; 4PZP A; 4B3R C; 1T5D X; 3H2T A; 4B3T C; 2Y27 A; 1FJG C; 4GS5 A; 3ETO A; 3C5E A; 2UXB C; 2VQE C; 3SO4 A; 3N54 B; 5BST A; 2UXC C; 5BSW A; 4DV2 C; 1MXA A; 3A9V A; 5BR8 C; 5K8F A; 3CJE A; 5KEI A; 2ONF A; 3LAX A; 5IT9 D; 5ADZ A; 3KXW A; 2QL8 A; 4WV3 A; 2UUB C; 3AF5 A; 4K0K C; 3LNV A; 2P2B A; 3IPL A; 1N2F A; 1NYE A; 3GKU A; 2HJG A; 4BBY A; 4U5Y D; 2BH1 X; 3E7X A; 4PHT A; 1IBM C; 2ZM6 C; 2YWC A; 1HNZ C; 3S82 A; 1HNX C; 4KHP C; 1MKY A; 4G1I A; 4X62 C; 2YCB A; 5BSV A; 1XMQ C; 1XRA A; 4D56 A; 1N33 C; 5E7Q A; 3VNQ A; 4GKJ C; 3IEV A; 4JI5 C; 4DV0 C; 4B3S C; 3TUF A; 1HR0 C; 3UZ0 A; 3B7W A; 5A19 A; 4RMN A; 2E8F A; 2QW0 X; 4DCV A; 5LMU C; 2PT7 G; 4DR2 C; 1PG4 A; 2JMP A; 3I08 A; 3CW9 A; 4DV3 C; 4JM1 A; 4DG9 A; 4NOZ A; 1BA3 A; 1USP A; 5GTD A; 3JAM D; 3J80 D; 2D1R A; 1PA4 A; 5KYV A; 4BCA A; 5CZX A; 1ZB9 A; 2EGT A; 1LCI A; 4EAT A; 5A2Q D; 4MTN A; 1O93 A; 4DV5 C; 1KKG A; 4DR6 C; 2AYA A; 4ZJZ A; 4ISB A; 1MD9 A; 1MDF A; 4DV6 C; 1O92 A; 4JI4 C; 3NYR A; 3AF6 A; 3NYQ A; 3PES A; 2D7V A; 3GPC A; 3GR1 A; 4IR7 A; 2UXD C; 4G36 A; 2F4V C; 2UUC C; 4DCU A; 2PRO A; 5A1I A; 2VQF C; 4DR4 C; 4JI0 C; 1XRB A; 1MDB A; 4XX2 A; 4I9F A; 2QVX X; 4L4Q A; 4LE5 A; 3R9X A; 2D1T A; 4FTF A; 1J5E C; 4GXR A; 4DUY C; 3NI2 A; 2OPL A; 4NXM C; 2P2J A; 3VNS A; 3T1Y C; 2OPL B; 1QM4 A; 1XNQ C; 1EGA A; 4DR5 C; 2VSQ A; 4JI3 C; 2CY1 A; 2VZE A; 2D1S A; 4LFB C; 2CXC A; 3L8C A; 1HNW C; 2P2M A;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
