4P19A

Closed, apo inward-facing state of the glutamate transporter homologue gltph
Total Genus 158
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
158
Knots found
sequence length
414
structure length
414
Chain Sequence
YIEYPVLQKILIGLILGAIVGLILGHYGYAHAVHTYVKPFGDLFVRLLCMLVMPIVFASLVVGAASISPARLGRVGVKIVVYYLLTSAFAVTLGIIMARLFNPGAGIHLAVGGQQFQPHQAPPLVHILLDIVPTNPFGALANGQVLPTIFFAIILGIAITYLMNSENEKVRKSAETLLDAINGLAEAMYKIVNGVMQYAPIGVFALIAYVMAEQGVHVVGELAKVTAAVYVGLTLQILLVYFVLLKIYGIDPISFIKHAKDAMLTAFVTRSSSGTLPVTMRVAKEMGISEGIYSFTLPLGATINMDGTALYQGVATFFIANALGSHLTVGQQLTIVLTAVLASIGTAGVPGAGAIMLCMVLHSVGLPLTDPNVAAAYAMILGIDAILDMGRTMVNVTGDLTGTAIVAKTEGTLV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Coupled ion binding and structural transitions along the transport cycle of glutamate transporters.
pubmed doi rcsb
molecule tags Transport protein
source organism Pyrococcus horikoshii
molecule keywords 425aa long hypothetical proton glutamate symport protein
total genus 158
structure length 414
sequence length 414
chains with identical sequence B, C
other databases KnotProt 2.0: S +31
ec nomenclature
pdb deposition date 2014-02-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00375 SDF Sodium:dicarboxylate symporter family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.3860.10 Mainly Alpha Orthogonal Bundle Proton glutamate symport protein Sodium:dicarboxylate symporter 4p19A00
4KY0A 4OYFA 4P1AA 4P3JA 1XFHA 3KBCA 2NWLA 2NWXA 5DWYA 5CFYA 4P19A 5E9SA 4OYEA 3V8FA 2NWWA
chains in the Genus database with same CATH superfamily
4KY0A 4OYFA 4P1AA 4P3JA 1XFHA 3KBCA 2NWLA 2NWXA 5DWYA 5CFYA 4P19A 5E9SA 4OYEA 3V8FA 2NWWA
chains in the Genus database with same CATH topology
4KY0A 4OYFA 4P1AA 4P3JA 1XFHA 3KBCA 2NWLA 2NWXA 5DWYA 5CFYA 4P19A 5E9SA 4OYEA 3V8FA 2NWWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4KY0 A;  4OYF A;  4P1A A;  4P3J A;  1XFH A;  3KBC A;  2NWL A;  2NWX A;  5DWY A;  5CFY A;  4P19 A;  5E9S A;  4OYE A;  3V8F A;  2NWW A; 
#chains in the Genus database with same CATH topology
 4KY0 A;  4OYF A;  4P1A A;  4P3J A;  1XFH A;  3KBC A;  2NWL A;  2NWX A;  5DWY A;  5CFY A;  4P19 A;  5E9S A;  4OYE A;  3V8F A;  2NWW A; 
#chains in the Genus database with same CATH homology
 4KY0 A;  4OYF A;  4P1A A;  4P3J A;  1XFH A;  3KBC A;  2NWL A;  2NWX A;  5DWY A;  5CFY A;  4P19 A;  5E9S A;  4OYE A;  3V8F A;  2NWW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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