4P1AA

Thallium-bound inward-facing state of the glutamate transporter homologue gltph
Total Genus 155
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
155
Knots found
sequence length
413
structure length
413
Chain Sequence
YIEYPVLQKILIGLILGAIVGLILGHYGYAHAVHTYVKPFGDLFVRLLCMLVMPIVFASLVVGAASISPARLGRVGVKIVVYYLLTSAFAVTLGIIMARLFNPGAGIHLAVGGQQFQPHQAPPLVHILLDIVPTNPFGALANGQVLPTIFFAIILGIAITYLMNSENEKVRKSAETLLDAINGLAEAMYKIVNGVMQYAPIGVFALIAYVMAEQGVHVVGELAKVTAAVYVGLTLQILLVYFVLLKIYGIDPISFIKHAKDAMLTAFVTRSSSGTLPVTMRVAKEMGISEGIYSFTLPLGATINMDGTALYQGVATFFIANALGSHLTVGQQLTIVLTAVLASIGTAGVPGAGAIMLCMVLHSVGLPLTDPNVAAAYAMILGIDAILDMGRTMVNVTGDLTGTAIVAKTEGTL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Coupled ion binding and structural transitions along the transport cycle of glutamate transporters.
pubmed doi rcsb
molecule tags Transport protein
source organism Pyrococcus horikoshii
molecule keywords GltPh
total genus 155
structure length 413
sequence length 413
chains with identical sequence B, C
other databases KnotProt 2.0: S +31
ec nomenclature
pdb deposition date 2014-02-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00375 SDF Sodium:dicarboxylate symporter family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.3860.10 Mainly Alpha Orthogonal Bundle Proton glutamate symport protein Sodium:dicarboxylate symporter 4p1aA00
3V8FA 2NWWA 5E9SA 4OYFA 4OYEA 2NWXA 2NWLA 4KY0A 4P3JA 4P19A 5CFYA 1XFHA 4P1AA 3KBCA 5DWYA
chains in the Genus database with same CATH superfamily
3V8FA 2NWWA 5E9SA 4OYFA 4OYEA 2NWXA 2NWLA 4KY0A 4P3JA 4P19A 5CFYA 1XFHA 4P1AA 3KBCA 5DWYA
chains in the Genus database with same CATH topology
3V8FA 2NWWA 5E9SA 4OYFA 4OYEA 2NWXA 2NWLA 4KY0A 4P3JA 4P19A 5CFYA 1XFHA 4P1AA 3KBCA 5DWYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3V8F A;  2NWW A;  5E9S A;  4OYF A;  4OYE A;  2NWX A;  2NWL A;  4KY0 A;  4P3J A;  4P19 A;  5CFY A;  1XFH A;  4P1A A;  3KBC A;  5DWY A; 
#chains in the Genus database with same CATH topology
 3V8F A;  2NWW A;  5E9S A;  4OYF A;  4OYE A;  2NWX A;  2NWL A;  4KY0 A;  4P3J A;  4P19 A;  5CFY A;  1XFH A;  4P1A A;  3KBC A;  5DWY A; 
#chains in the Genus database with same CATH homology
 3V8F A;  2NWW A;  5E9S A;  4OYF A;  4OYE A;  2NWX A;  2NWL A;  4KY0 A;  4P3J A;  4P19 A;  5CFY A;  1XFH A;  4P1A A;  3KBC A;  5DWY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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