5B0VA

Crystal structure of marburg virus vp40 dimer
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
266
structure length
258
Chain Sequence
GITPNYVGDLNLDDQFKGNVCHAFTLEAIIDISNERTVKGVPAWLPLGIMSNFEYPLAHTVAALLTGSYTITQFTHNGQKFVRVNRLGTGIPAHPLRMLREGNQAFIQNMVIPRNFNQFTYNLTNLVLSVQKLPDDAWRPSKDKLIGNTMHPAVSIHPNLPPIVLPTVKKQAYRQHKNPNNGPLLAISGILHQLRVEKVPEKTSLFRISLPADMFSVKEGMMENSPVVYFQAPENFPLNGFNNRQVVLAYANPTLSAV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Viral protein
molecule keywords Matrix protein VP40
publication title Crystal Structure of Marburg Virus VP40 Reveals a Broad, Basic Patch for Matrix Assembly and a Requirement of the N-Terminal Domain for Immunosuppression
pubmed doi rcsb
source organism Lake victoria marburgvirus (strain musoke-80)
total genus 45
structure length 258
sequence length 266
chains with identical sequence B
ec nomenclature
pdb deposition date 2015-11-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07447 VP40 Matrix protein VP40
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.20.20 Mainly Beta Distorted Sandwich Topoisomerase I; domain 3 Topoisomerase I; domain 3 5b0vA01
5B0VA 1ES6A 1H2CA 3TCQA 4LDBA 4LDDA 4LD8A 1H2DA 4LDMA
chains in the Genus database with same CATH superfamily
2GAJA 3PWTA 1ECLA 2O19A 4LP7A 2YKDA 4CGYA 4HIWA 4RULA 1CY2A 1CY0A 2O59A 4LDMA 1MW8X 2O5CA 4G1GA 1CYYA 4V23A 3PX7A 4HIYA 2GAIA 4LDDA 3F1JA 4HITA 1CY6A 4HI5A 1ES6A 1H2CA 4HI6A 4LDBA 2O5EA 5D5HA 1CY4A 4LD8A 4HIUA 3TCQA 4CHTA 1MW9X 4G1OA 5B0VA 1CY8A 1I7DA 2O54A 1CY1A 4D4TA 2VQPA 1D6MA 1CY7A 1CY9A 4G1LA 1H2DA
chains in the Genus database with same CATH topology
4LP7A 2YKDA 4HIWA 4LDMA 4G1GA 4V23A 4HIYA 4LDDA 3F1JA 4HITA 4HI5A 1ES6A 1H2CA 4HI6A 4LDBA 4LD8A 4HIUA 4G1OA 5B0VA 4D4TA 2VQPA 3TCQA 4G1LA 1H2DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5B0V A;  1ES6 A;  1H2C A;  3TCQ A;  4LDB A;  4LDD A;  4LD8 A;  1H2D A;  4LDM A; 
#chains in the Genus database with same CATH topology
 2GAJ A;  3PWT A;  1ECL A;  2O19 A;  4LP7 A;  2YKD A;  4CGY A;  4HIW A;  4RUL A;  1CY2 A;  1CY0 A;  2O59 A;  4LDM A;  1MW8 X;  2O5C A;  4G1G A;  1CYY A;  4V23 A;  3PX7 A;  4HIY A;  2GAI A;  4LDD A;  3F1J A;  4HIT A;  1CY6 A;  4HI5 A;  1ES6 A;  1H2C A;  4HI6 A;  4LDB A;  2O5E A;  5D5H A;  1CY4 A;  4LD8 A;  4HIU A;  3TCQ A;  4CHT A;  1MW9 X;  4G1O A;  5B0V A;  1CY8 A;  1I7D A;  2O54 A;  1CY1 A;  4D4T A;  2VQP A;  1D6M A;  1CY7 A;  1CY9 A;  4G1L A;  1H2D A; 
#chains in the Genus database with same CATH homology
 4LP7 A;  2YKD A;  4HIW A;  4LDM A;  4G1G A;  4V23 A;  4HIY A;  4LDD A;  3F1J A;  4HIT A;  4HI5 A;  1ES6 A;  1H2C A;  4HI6 A;  4LDB A;  4LD8 A;  4HIU A;  4G1O A;  5B0V A;  4D4T A;  2VQP A;  3TCQ A;  4G1L A;  1H2D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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