6EN4D

Sf3b core in complex with a splicing modulator
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
Knots found
sequence length
93
structure length
93
Chain Sequence
PDLIFCRKQAGVAIGRLCEKCDGKCVICDSYVRPCTLVRICDECNYGSYQGRCVICGGPGVSDAYYCKECTIQEKDRDGCPKIVNLGSSKTDL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis of Splicing Modulation by Antitumor Macrolide Compounds.
pubmed doi rcsb
molecule tags Splicing
source organism Homo sapiens
molecule keywords Splicing factor 3B subunit 3
total genus 16
structure length 93
sequence length 93
other databases KnotProt 2.0: S -31
ec nomenclature
pdb deposition date 2017-10-04
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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