8E1OA

Crystal structure of htead2 bound to a methoxypyridine lipid pocket binder
Total Genus 55
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
55
sequence length
230
structure length
208
Chain Sequence
AWQARGLGTARLQLVEFSAFVEPPDAVDSYQRHLFVHISQHPPLESVDVRQIYDKFPEKKGGLRELYDRGPPHAFFLVKFWADLNWGFYGVSSQYESLEHMTLTCSSKVCSFGKQVVEKVETERAQLEDGRFVYRLLRSPMCEYLVNFLHKLRQLPERYMMNSVLENFTILQVVTNRDTQELLLCTAYVFEVSTSERGAQHHIYRLVR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Transcription/inhibitor
molecule keywords Transcriptional enhancer factor TEF-4
publication title Targeting the Hippo pathway in cancers via ubiquitination dependent TEAD degradation
rcsb
source organism Homo sapiens
total genus 55
structure length 208
sequence length 230
chains with identical sequence B
ec nomenclature
pdb deposition date 2022-08-10
Image from the rcsb pdb (www.rcsb.org)
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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