Found 115 chains in Genus chains table. Displaying 1 - 50. Applied filters: Proteins

Search results query ec: 1.1.1.42

Total Genus Sequence Length pdb Title
149 411 6io0A Human idh1 r132c mutant complexed with compound a.
274 739 5kvuA Crystal structure of isocitrate dehydrogenase-2 in complex with nadp(+) from mycobacterium tuberculosis
215 735 5z16A A novel dimeric isocitrate dehydrogenase from acinetobacter baumannii
148 409 5yziA Crystal structure of mouse cytosolic isocitrate dehydrogenase complexed with cadmium
123 418 5m2eA Apo structure of pseudomonas aeruginosa isocitrate dehydrogenase, icd.
147 414 5lgeA Crystal structure of human idh1 mutant (r132h) in complex with nadp+ and an inhibitor related to bay 1436032
132 412 5l58A Crystal structure of iso-citrate dehydrogenase 1 [idh1 (r132h)] in complex with a novel inhibitor (compound 2)
142 412 5l57A Crystal structure of iso-citrate dehydrogenase r132h in complex with a novel inhibitor (compound 13a)
155 413 5i95A Crystal structure of human mitochondrial isocitrate dehydrogenase r140q mutant homodimer bound to nadph and alpha-ketoglutaric acid
142 414 5icdA Regulation of an enzyme by phosphorylation at the active site
158 417 5i96A Crystal structure of human mitochondrial isocitrate dehydrogenase (idh2) r140q mutant homodimer in complex with ag-221 (enasidenib) inhibitor.
138 414 9icdA Catalytic mechanism of nadp+-dependent isocitrate dehydrogenase: implications from the structures of magnesium-isocitrate and nadp+ complexes
138 414 8icdA Regulation of an enzyme by phosphorylation at the active site
140 414 7icdA Regulation of an enzyme by phosphorylation at the active site
141 414 6icdA Regulation of an enzyme by phosphorylation at the active site
140 419 6c0eA Crystal structure of isocitrate dehydrogenase from legionella pneumophila with bound nadph with an alpha-ketoglutarate adduct
162 416 6bl0A Novel modes of inhibition of wild-type idh1:direct covalent modification of his315 with cmpd11
158 414 6bkxA Novel modes of inhibition of wild-type idh1: direct covalent modification of his315 with cmpd1
160 416 6bl1A Novel modes of inhibition of wild-type idh1: direct covalent modification of his315 with cmpd13
156 416 6bkyA Novel binding modes of inhibition of wild-type idh1: allosteric inhibition with cmpd2
148 412 6bkzA Novel modes of inhibition of wild-type idh1: non-equivalent allosteric inhibition with cmpd3
159 416 6bl2A Novel modes of inhibition of wild-type idh1: direct covalent modification of his315 with cmpd15
145 410 6b0zA Idh1 r132h mutant in complex with idh305
156 418 6adiA Crystal structures of idh2 r140q in complex with ag-881
144 412 6adgA Crystal structures of idh1 r132h in complex with ag-881
151 418 5yfnA Human isocitrate dehydrogenase 1 bound with isocitrate
151 409 5yfmA Human isocitrate dehydrogenase 1 bound with nadp
157 412 5yzhA Crystal structure of mouse cytosolic isocitrate dehydrogenase
263 735 4zdaA Crystal structure of isocitrate dehydrogenase in complex with isocitrate and mn from m. smegmatis
130 410 4xs3A Crystal structure of a metabolic reductase with (e)-1-benzyl-5-((1-methyl-5-oxo-2-thioxoimidazolidin-4-ylidene)methyl)pyridin-2(1h)-one
141 412 4umxA Idh1 r132h in complex with cpd 1
143 411 4umyA Idh1 r132h in complex with cpd 1
140 415 4bnpA 3d structure of e. coli isocitrate dehydrogenase k100m mutant in complex with isocitrate and magnesium(ii)
144 401 4aouA Ctidh bound to nadp. the complex structures of isocitrate dehydrogenase from clostridium thermocellum and desulfotalea psychrophila, support a new active site locking mechanism
140 415 4ajcA 3d structure of e. coli isocitrate dehydrogenase k100m mutant in complex with alpha-ketoglutarate, calcium(ii) and adenine nucleotide phosphate
137 415 4ajrA 3d structure of e. coli isocitrate dehydrogenase k100m mutant in complex with alpha-ketoglutarate, magnesium(ii) and nadph - the product complex
122 400 4aoyA Open ctidh. the complex structures of isocitrate dehydrogenase from clostridium thermocellum and desulfotalea psychrophila, support a new active site locking mechanism
142 415 4ajbA 3d structure of e. coli isocitrate dehydrogenase k100m mutant in complex with isocitrate, magnesium(ii) and thionadp
141 415 4ajaA 3d structure of e. coli isocitrate dehydrogenase in complex with isocitrate, calcium(ii) and thionadp
153 402 4aovA Dpidh-nadp. the complex structures of isocitrate dehydrogenase from clostridium thermocellum and desulfotalea psychrophila, support a new active site locking mechanism
138 416 4aj3A 3d structure of e. coli isocitrate dehydrogenase in complex with isocitrate, calcium(ii) and nadp - the pseudo-michaelis complex
138 415 4ajsA 3d structure of e. coli isocitrate dehydrogenase k100m mutant in complex with isocitrate, magnesium(ii), adenosine 2',5'-biphosphate and ribosylnicotinamide-5'-phosphate
143 401 3us8A Crystal structure of an isocitrate dehydrogenase from sinorhizobium meliloti 1021
143 410 5tqhA Idh1 r132h mutant in complex with idh889
140 411 5sunA Idh1 r132h in complex with idh146
150 408 5svnA Structure of idh2 mutant r172k
146 409 5svfA Idh1 r132h in complex with idh125
149 410 5svoA Structure of idh2 mutant r140q
109 411 5k11A Cryo-em structure of isocitrate dehydrogenase (idh1) in inhibitor-bound state
98 411 5k10A Cryo-em structure of isocitrate dehydrogenase (idh1)