Found 190 chains in Genus chains table. Displaying 1 - 50. Applied filters: Proteins

Search results query ec: 3.1.4.35

Total Genus Sequence Length pdb Title
121 323 7farA Crystal structure of pde5a in complex with inhibitor l12
123 323 7faqA Crystal structure of pde5a in complex with inhibitor l1
125 316 7f0iA Phosphodiesterase-9a in complex with inhibitor 4b
122 315 8bpyA X-ray structure of pde9a in complex with inhibitor 13a
126 320 6lzzA Crystal structure of the pde9 catalytic domain in complex with inhibitor 4a
135 324 6l6eA Human pde5 catalytic core in complex with avanafil
143 815 7jsnB Structure of the visual signaling complex between transducin and phosphodiesterase 6
2 87 7jsnC Structure of the visual signaling complex between transducin and phosphodiesterase 6
162 820 7jsnA Structure of the visual signaling complex between transducin and phosphodiesterase 6
107 406 6x88A Pde6 chicken gaf domain
123 312 7bpiA The crystal structue of pde10a complexed with 14
115 325 6vbiA Crystal structure of pde5 in complex with a non-competitive inhibitor
0 4 5e8fD Structure of fully modified geranylgeranylated pde6c peptide in complex with pde6d
185 813 6mzbA Cryo-em structure of phosphodiesterase 6
173 812 6mzbB Cryo-em structure of phosphodiesterase 6
130 328 6msaA Novel, potent, selective and brain penetrant phosphodiesterase 10a inhibitors
1 86 6mzbC Cryo-em structure of phosphodiesterase 6
134 322 6mscA Novel, potent, selective and brain penetrant phosphodiesterase 10a inhibitors
120 323 5znlA Crystal structure of pde10a catalytic domain complexed with lhb-6
113 324 6ijiA Crystal structure of pde10 in complex with inhibitor 2b
122 322 6ijhA Crystal structure of pde10 in complex with inhibitor af-399/14387019
130 322 6a3nA Crystal structure of the pde9 catalytic domain in complex with inhibitor 2
127 324 3tggA A novel series of potent and selective pde5 inhibitor2
127 324 3tgeA A novel series of potent and selective pde5 inhibitor1
125 326 6acbA Crystal structure of pde5 in complex with inhibitor lw1805
115 312 5k9rA Pde10a with imidazopyrazine inhibitor
130 313 5i2rA Human pde10a in complex with 3-(2-phenylpyrazol-3-yl)-1-[3-(trifluoromethoxy)phenyl]pyridazin-4-one
121 326 5zz2A Crystal structure of pde5 in complex with inhibitor lw1634
121 322 5xujA Crystal structure of pde10a in complex with 7-(4-chlorophenyl)-2-methylpyrazolo[1,5-a]pyrimidine
125 322 5xuiA Crystal structure of pde10a in complex with 2-methyl-5-[2-([1,2,4]triazolo[1,5-a]pyrimidin-2-yl)et hyl]pyrazolo[1,5-a]pyrimidin-7-ol
126 307 5c29A Pde10 complexed with 6-chloro-2-cyclopropyl-5-methyl-n-propyl-pyrimidin-4-amine
126 308 5c2hA Pde10 complexed with 6-chloro-n-[(2,4-dimethylthiazol-5-yl)methyl]-5-methyl-2-[3-(2-quinolyl)propoxy]pyrimidin-4-amine
127 323 5c2eA Pde10 complexed with6-chloro-n-[(2,4-dimethylthiazol-5-yl)methyl]-5-methyl-2-[2-(2-pyridyl)ethoxy]pyrimidin-4-amine
136 325 5c28A Pde10 complexed with 6-chloro-2-cyclopropyl-5-methyl-pyrimidin-4-amine
135 325 5c1wA Pde10 complexed with 4,6-dichloro-2-cyclopropyl-5-methyl-pyrimidine
133 323 5c2aA Pde10 complexed with 6-chloro-2-cyclopropyl-n-[(2,4-dimethylthiazol-5-yl)methyl]-5-methyl-pyrimidin-4-amine
125 315 5b4lA Crystal structure of the catalytic domain of human pde10a complexed with 1-(cyclopropylmethyl)-5-(2-(2,3-dihydro-1h-imidazo[1,2-a]benzimidazol-1-yl)ethoxy)-3-(1-phenyl-1h-pyrazol-5-yl)pyridazin-4(1h)-one
126 322 4ys7A Co-crystal structure of 2-[2-(5,8-dimethyl[1,2,4]triazolo[1,5-a]pyrazin-2-yl)ethyl]-3-methyl-3h-imidazo[4,5-f]quinoline (compound 39) with pde10a
128 321 4yqhA 2-[2-(4-phenyl-1h-imidazol-2-yl)ethyl]quinoxaline (sunovion compound 14) co-crystallized with pde10a
133 328 4e90A Human phosphodiesterase 9 in complex with inhibitors
124 307 4dffA The sar development of dihydroimidazoisoquinoline derivatives as phosphodiesterase 10a inhibitors for the treatment of schizophrenia
128 318 4ddlA Pde10a crystal structure complexed with novel inhibitor
124 312 4bbxA Discovery of a potent, selective and orally active pde10a inhibitor for the treatment of schizophrenia
131 320 4aelA Pde10a in complex with the inhibitor az5
140 328 4ajfA Identification and structural characterization of pde10 fragment inhibitors
131 321 4ajgA Identification and structural characterization of pde10 fragment inhibitors
133 324 4ajdA Identification and structural characterization of pde10 fragment inhibitors
135 320 4ajmA Development of a plate-based optical biosensor methodology to identify pde10 fragment inhibitors
123 315 3wylA Crystal structure of the catalytic domain of pde10a complexed with 5-methoxy-3-(1-phenyl-1h-pyrazol-5-yl)-1-(3-(trifluoromethyl)phenyl)pyridazin-4(1h)-one
125 324 3wi2A Crystal structure of pde10a in complex with inhibitor