Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 1c4z_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LEU 4.A N GLN 35.A O no hydrogen 3.069 N/A LEU 6.A N TYR 37.A O no hydrogen 3.098 N/A VAL 8.A N GLU 39.A O no hydrogen 2.828 N/A ARG 10.A NE GLU 43.A OE1 no hydrogen 2.763 N/A ARG 10.A NH1 GLU 54.A OE1 no hydrogen 2.948 N/A ARG 10.A NH2 GLU 43.A OE1 no hydrogen 3.101 N/A ARG 10.A NH2 GLU 43.A OE2 no hydrogen 3.063 N/A ARG 10.A NH2 GLU 54.A OE1 no hydrogen 3.168 N/A HIS 12.A ND1 ASP 11.A O no hydrogen 2.324 N/A ASP 16.A N HIS 12.A O no hydrogen 2.973 N/A ALA 17.A N ILE 13.A O no hydrogen 2.866 N/A LEU 18.A N ILE 14.A O no hydrogen 3.028 N/A VAL 19.A N ASP 15.A O no hydrogen 3.174 N/A ARG 20.A N ASP 16.A O no hydrogen 2.886 N/A ARG 20.A NH1 ARG 5.A O no hydrogen 2.818 N/A LEU 21.A N ALA 17.A O no hydrogen 2.843 N/A GLU 22.A N LEU 18.A O no hydrogen 2.849 N/A MET 23.A N VAL 19.A O no hydrogen 3.268 N/A ILE 24.A N ARG 20.A O no hydrogen 3.100 N/A ALA 25.A N LEU 21.A O no hydrogen 3.008 N/A MET 26.A N GLU 22.A O no hydrogen 3.095 N/A GLU 27.A N MET 23.A O no hydrogen 3.082 N/A ASP 31.A N ASN 28.A O no hydrogen 3.160 N/A ASP 31.A N ASN 28.A OD1 no hydrogen 3.272 N/A LEU 32.A N PRO 29.A O no hydrogen 2.543 N/A LYS 33.A N ALA 30.A O no hydrogen 2.539 N/A LYS 33.A NZ ASN 223.A OD1 no hydrogen 3.265 N/A LYS 33.A NZ GLU 224.A OE2 no hydrogen 2.681 N/A LYS 34.A N ASP 31.A O no hydrogen 3.296 N/A LYS 34.A NZ ASN 1.A O no hydrogen 2.696 N/A LYS 34.A NZ ASP 31.A OD2 no hydrogen 3.090 N/A VAL 38.A N ASP 47.A OD2 no hydrogen 2.656 N/A GLU 39.A N LEU 6.A O no hydrogen 2.777 N/A GLU 41.A N VAL 8.A O no hydrogen 2.498 N/A GLU 43.A N PHE 40.A O no hydrogen 3.030 N/A ASP 47.A N TYR 37.A OH no hydrogen 3.058 N/A GLY 49.A N ASP 47.A OD1 no hydrogen 2.839 N/A SER 52.A N ASP 47.A OD1 no hydrogen 3.076 N/A SER 52.A OG LEU 36.A O no hydrogen 2.971 N/A SER 52.A OG ASP 47.A OD2 no hydrogen 2.729 N/A LYS 53.A N GLY 49.A O no hydrogen 2.642 N/A LYS 53.A NZ THR 323.A O no hydrogen 2.944 N/A LYS 53.A NZ ASN 326.A OD1 no hydrogen 3.196 N/A GLU 54.A N GLY 50.A O no hydrogen 2.601 N/A PHE 55.A N VAL 51.A O no hydrogen 2.840 N/A PHE 56.A N SER 52.A O no hydrogen 3.121 N/A GLN 57.A N LYS 53.A O no hydrogen 3.065 N/A GLN 57.A NE2 THR 323.A OG1 no hydrogen 3.357 N/A LEU 58.A N GLU 54.A O no hydrogen 2.978 N/A VAL 59.A N PHE 55.A O no hydrogen 3.015 N/A VAL 60.A N PHE 56.A O no hydrogen 2.944 N/A GLU 61.A N GLN 57.A O no hydrogen 2.792 N/A GLU 62.A N LEU 58.A O no hydrogen 2.894 N/A ILE 63.A N VAL 59.A O no hydrogen 3.044 N/A PHE 64.A N VAL 60.A O no hydrogen 3.282 N/A ASN 65.A N GLU 62.A O no hydrogen 3.098 N/A ASP 67.A N ASN 65.A OD1 no hydrogen 2.699 N/A ILE 68.A N ASN 65.A O no hydrogen 3.246 N/A GLY 69.A N PRO 66.A O no hydrogen 2.486 N/A THR 72.A N TRP 81.A O no hydrogen 3.067 N/A ASP 74.A N LEU 79.A O no hydrogen 3.042 N/A THR 77.A N ASP 74.A O no hydrogen 2.944 N/A THR 77.A N ASP 74.A OD2 no hydrogen 3.032 N/A LYS 78.A N ASP 74.A O no hydrogen 2.701 N/A PHE 80.A N HIS 113.A O no hydrogen 2.783 N/A TRP 81.A N THR 72.A O no hydrogen 3.098 N/A ASN 83.A N MET 70.A O no hydrogen 3.217 N/A ASN 83.A ND2 GLY 69.A O no hydrogen 3.421 N/A SER 85.A N ASN 83.A OD1 no hydrogen 2.699 N/A SER 86.A N ASN 83.A O no hydrogen 3.124 N/A SER 86.A OG THR 89.A OG1 no hydrogen 2.378 N/A THR 89.A OG1 SER 86.A OG no hydrogen 2.378 N/A PHE 93.A N THR 89.A O no hydrogen 3.032 N/A THR 94.A N GLU 90.A O no hydrogen 3.004 N/A THR 94.A OG1 GLU 90.A O no hydrogen 2.921 N/A THR 94.A OG1 ALA 213.A O no hydrogen 3.365 N/A LEU 95.A N GLY 91.A O no hydrogen 2.819 N/A ILE 96.A N GLN 92.A O no hydrogen 3.202 N/A GLY 97.A N PHE 93.A O no hydrogen 3.205 N/A ILE 98.A N THR 94.A O no hydrogen 2.848 N/A VAL 99.A N LEU 95.A O no hydrogen 2.750 N/A LEU 100.A N ILE 96.A O no hydrogen 2.705 N/A GLY 101.A N GLY 97.A O no hydrogen 3.124 N/A LEU 102.A N ILE 98.A O no hydrogen 2.982 N/A ALA 103.A N VAL 99.A O no hydrogen 2.954 N/A ILE 104.A N GLY 101.A O no hydrogen 3.187 N/A TYR 105.A N GLY 101.A O no hydrogen 3.322 N/A ASN 106.A N ALA 103.A O no hydrogen 3.370 N/A ASN 107.A N ILE 104.A O no hydrogen 3.462 N/A ASN 107.A ND2 VAL 298.A O no hydrogen 3.232 N/A CYS 108.A N ALA 103.A O no hydrogen 3.003 N/A LEU 110.A N ILE 240.A O no hydrogen 2.841 N/A VAL 118.A N PRO 115.A O no hydrogen 3.089 N/A ARG 120.A N MET 116.A O no hydrogen 3.181 N/A LYS 121.A N VAL 117.A O no hydrogen 2.926 N/A LYS 121.A NZ LEU 203.A O no hydrogen 3.115 N/A LYS 121.A NZ ASN 204.A OD1 no hydrogen 3.133 N/A LEU 122.A N VAL 118.A O no hydrogen 3.044 N/A MET 123.A N TYR 119.A O no hydrogen 3.315 N/A MET 123.A N ARG 120.A O no hydrogen 3.001 N/A GLY 124.A N LYS 121.A O no hydrogen 2.852 N/A LYS 125.A N ARG 120.A O no hydrogen 3.072 N/A GLY 127.A N ASN 204.A OD1 no hydrogen 2.859 N/A THR 128.A OG1 ASP 131.A OD2 no hydrogen 2.893 N/A LEU 132.A N THR 128.A O no hydrogen 3.076 N/A LEU 132.A N PHE 129.A O no hydrogen 3.090 N/A GLY 133.A N ARG 130.A O no hydrogen 3.039 N/A ASP 134.A N ASP 131.A O no hydrogen 3.233 N/A SER 135.A OG HIS 136.A ND1 no hydrogen 2.670 N/A HIS 136.A N LEU 132.A O no hydrogen 2.914 N/A HIS 136.A ND1 SER 135.A OG no hydrogen 2.670 N/A TYR 140.A N HIS 136.A O no hydrogen 2.970 N/A GLN 141.A N PRO 137.A O no hydrogen 2.997 N/A SER 142.A N VAL 138.A O no hydrogen 3.083 N/A SER 142.A OG VAL 138.A O no hydrogen 3.334 N/A LEU 143.A N LEU 139.A O no hydrogen 3.128 N/A LYS 144.A N TYR 140.A O no hydrogen 2.773 N/A LYS 144.A NZ GLU 148.A OE1 no hydrogen 2.477 N/A LYS 144.A NZ GLU 148.A OE2 no hydrogen 3.134 N/A ASP 145.A N GLN 141.A O no hydrogen 2.890 N/A LEU 146.A N SER 142.A O no hydrogen 2.857 N/A LEU 147.A N LEU 143.A O no hydrogen 3.149 N/A GLU 148.A N LYS 144.A O no hydrogen 2.848 N/A TYR 149.A N LEU 146.A O no hydrogen 3.423 N/A TYR 149.A OH ASP 156.A OD2 no hydrogen 2.744 N/A ASN 152.A N ASP 156.A OD2 no hydrogen 3.110 N/A ASP 155.A N ASN 152.A O no hydrogen 3.121 N/A ASP 155.A N ASN 152.A OD1 no hydrogen 2.734 N/A ASP 156.A N ASN 152.A O no hydrogen 2.782 N/A MET 157.A N VAL 153.A O no hydrogen 2.952 N/A ILE 163.A N TYR 175.A O no hydrogen 2.863 N/A GLN 165.A N MET 173.A O no hydrogen 3.229 N/A PHE 169.A N ASP 167.A O no hydrogen 2.741 N/A TYR 175.A N ILE 163.A O no hydrogen 2.862 N/A LEU 177.A N PHE 161.A O no hydrogen 3.056 N/A LYS 178.A NZ GLU 193.A OE1 no hydrogen 3.296 N/A LYS 178.A NZ GLU 193.A OE2 no hydrogen 2.785 N/A LYS 183.A N ASN 180.A O no hydrogen 3.022 N/A ILE 186.A N ILE 159.A O no hydrogen 3.314 N/A THR 187.A N ASN 190.A OD1 no hydrogen 3.060 N/A GLU 189.A N THR 187.A OG1 no hydrogen 3.077 N/A ASN 190.A ND2 PRO 185.A O no hydrogen 2.965 N/A ARG 191.A NH1 LEU 146.A O no hydrogen 2.735 N/A ARG 191.A NH1 TYR 149.A O no hydrogen 2.953 N/A ARG 191.A NH2 TYR 149.A O no hydrogen 3.301 N/A PHE 194.A N ASN 190.A O no hydrogen 3.145 N/A VAL 195.A N ARG 191.A O no hydrogen 2.987 N/A ASN 196.A N LYS 192.A O no hydrogen 2.959 N/A LEU 197.A N GLU 193.A O no hydrogen 2.924 N/A TYR 198.A N PHE 194.A O no hydrogen 2.914 N/A SER 199.A N VAL 195.A O no hydrogen 2.834 N/A SER 199.A OG VAL 195.A O no hydrogen 2.581 N/A ASP 200.A N ASN 196.A O no hydrogen 2.907 N/A TYR 201.A N LEU 197.A O no hydrogen 2.892 N/A LEU 203.A N SER 199.A O no hydrogen 3.366 N/A ASN 204.A N ASP 200.A O no hydrogen 2.822 N/A ASN 204.A ND2 GLY 127.A O no hydrogen 3.493 N/A ASN 204.A ND2 ASP 200.A O no hydrogen 3.429 N/A ASN 204.A ND2 ASP 200.A OD1 no hydrogen 2.951 N/A LYS 205.A N ASP 200.A O no hydrogen 3.377 N/A GLU 208.A N LYS 205.A O no hydrogen 3.182 N/A GLN 210.A N GLN 210.A OE1 no hydrogen 2.319 N/A GLN 210.A NE2 ASN 83.A O no hydrogen 3.642 N/A PHE 211.A N VAL 207.A O no hydrogen 2.976 N/A LYS 212.A N GLU 208.A O no hydrogen 2.817 N/A LYS 212.A NZ GLU 208.A OE2 no hydrogen 2.751 N/A ALA 213.A N LYS 209.A O no hydrogen 3.284 N/A PHE 214.A N GLN 210.A O no hydrogen 3.123 N/A ARG 215.A N PHE 211.A O no hydrogen 2.722 N/A ARG 215.A NE LEU 122.A O no hydrogen 2.634 N/A ARG 215.A NH2 LEU 122.A O no hydrogen 2.716 N/A ARG 216.A N LYS 212.A O no hydrogen 2.815 N/A GLY 217.A N ALA 213.A O no hydrogen 2.807 N/A PHE 218.A N PHE 214.A O no hydrogen 2.895 N/A HIS 219.A N ARG 215.A O no hydrogen 2.856 N/A MET 220.A N ARG 216.A O no hydrogen 2.949 N/A MET 220.A N GLY 217.A O no hydrogen 3.278 N/A VAL 221.A N PHE 218.A O no hydrogen 3.238 N/A THR 222.A N HIS 219.A O no hydrogen 3.102 N/A THR 222.A OG1 PHE 218.A O no hydrogen 3.152 N/A ASN 223.A N HIS 219.A O no hydrogen 3.153 N/A ASN 223.A ND2 HIS 219.A O no hydrogen 3.527 N/A SER 225.A N ASN 223.A O no hydrogen 2.842 N/A ARG 232.A NH1 GLU 235.A OE2 no hydrogen 3.382 N/A GLU 234.A N GLU 234.A OE1 no hydrogen 2.455 N/A GLU 235.A N ARG 232.A O no hydrogen 3.128 N/A ILE 236.A N PRO 233.A O no hydrogen 2.698 N/A GLU 237.A N PRO 233.A O no hydrogen 3.220 N/A LEU 238.A N GLU 234.A O no hydrogen 3.046 N/A LEU 239.A N ILE 236.A O no hydrogen 3.213 N/A ILE 240.A N ILE 236.A O no hydrogen 3.184 N/A ILE 240.A N GLU 237.A O no hydrogen 3.033 N/A CYS 241.A N GLU 237.A O no hydrogen 2.690 N/A CYS 241.A SG VAL 112.A O no hydrogen 4.020 N/A CYS 241.A SG GLU 237.A O no hydrogen 3.296 N/A GLY 242.A N LEU 238.A O no hydrogen 2.999 N/A SER 243.A N ALA 296.A O no hydrogen 3.076 N/A ASP 247.A N ASN 245.A OD1 no hydrogen 3.087 N/A GLN 249.A N ASP 247.A O no hydrogen 2.350 N/A GLU 252.A N PHE 248.A O no hydrogen 2.618 N/A THR 254.A OG1 ALA 250.A O no hydrogen 2.971 N/A THR 254.A OG1 GLU 253.A O no hydrogen 2.448 N/A THR 254.A OG1 GLY 302.A O no hydrogen 3.051 N/A THR 255.A N GLU 252.A O no hydrogen 3.277 N/A THR 255.A OG1 LEU 251.A O no hydrogen 2.361 N/A THR 255.A OG1 GLU 252.A O no hydrogen 2.857 N/A THR 255.A OG1 GLU 253.A O no hydrogen 3.324 N/A GLU 256.A N MET 306.A O no hydrogen 2.938 N/A ASP 258.A N ILE 308.A O no hydrogen 3.096 N/A TYR 261.A OH LEU 330.A O no hydrogen 2.579 N/A THR 262.A OG1 TYR 261.A O no hydrogen 2.340 N/A THR 262.A OG1 ASP 264.A O no hydrogen 3.405 N/A SER 265.A OG TYR 261.A O no hydrogen 2.327 N/A SER 265.A OG THR 262.A O no hydrogen 3.488 N/A SER 265.A OG ASP 264.A O no hydrogen 2.441 N/A ARG 269.A N SER 265.A O no hydrogen 2.800 N/A GLU 270.A N VAL 266.A O no hydrogen 2.979 N/A PHE 271.A N LEU 267.A O no hydrogen 3.042 N/A TRP 272.A N ILE 268.A O no hydrogen 2.963 N/A TRP 272.A NE1 TYR 257.A OH no hydrogen 3.003 N/A GLU 273.A N ARG 269.A O no hydrogen 3.060 N/A ILE 274.A N GLU 270.A O no hydrogen 3.010 N/A ILE 274.A N PHE 271.A O no hydrogen 2.994 N/A VAL 275.A N PHE 271.A O no hydrogen 2.836 N/A HIS 276.A N TRP 272.A O no hydrogen 2.924 N/A SER 277.A OG GLU 273.A O no hydrogen 3.143 N/A SER 277.A OG ILE 274.A O no hydrogen 3.060 N/A PHE 278.A N VAL 275.A O no hydrogen 2.845 N/A THR 279.A N GLN 282.A OE1 no hydrogen 2.824 N/A GLN 282.A N THR 279.A O no hydrogen 2.414 N/A LYS 283.A N THR 279.A O no hydrogen 3.329 N/A ARG 284.A N ASP 280.A O no hydrogen 2.840 N/A ARG 284.A NH2 ARG 244.A O no hydrogen 3.130 N/A LEU 285.A N GLU 281.A O no hydrogen 2.872 N/A PHE 286.A N GLN 282.A O no hydrogen 2.792 N/A LEU 287.A N LYS 283.A O no hydrogen 3.222 N/A GLN 288.A N ARG 284.A O no hydrogen 2.972 N/A GLN 288.A NE2 GLY 292.A O no hydrogen 3.509 N/A PHE 289.A N LEU 285.A O no hydrogen 2.865 N/A THR 290.A N PHE 286.A O no hydrogen 2.845 N/A THR 290.A OG1 PHE 286.A O no hydrogen 3.001 N/A THR 291.A N LEU 287.A O no hydrogen 2.764 N/A THR 291.A OG1 LEU 287.A O no hydrogen 2.725 N/A THR 293.A N THR 291.A OG1 no hydrogen 3.373 N/A ARG 295.A N THR 293.A OG1 no hydrogen 3.180 N/A ARG 295.A NH1 GLY 242.A O no hydrogen 2.765 N/A ALA 296.A N SER 243.A O no hydrogen 3.027 N/A GLY 300.A N PRO 297.A O no hydrogen 3.210 N/A LEU 301.A N ASN 245.A OD1 no hydrogen 3.387 N/A LYS 303.A N GLY 300.A O no hydrogen 3.142 N/A LEU 304.A N LEU 301.A O no hydrogen 3.114 N/A ILE 307.A N ASN 326.A O no hydrogen 3.021 N/A ILE 308.A N GLU 256.A O no hydrogen 2.907 N/A ALA 309.A N LEU 328.A O no hydrogen 3.015 N/A LYS 310.A N ASP 258.A O no hydrogen 2.887 N/A ASN 311.A N LEU 330.A O no hydrogen 3.284 N/A ARG 317.A N THR 315.A OG1 no hydrogen 3.136 N/A THR 320.A N LEU 329.A O no hydrogen 3.092 N/A SER 321.A OG PHE 289.A O no hydrogen 3.179 N/A HIS 322.A N VAL 327.A O no hydrogen 3.140 N/A PHE 325.A N HIS 322.A O no hydrogen 3.015 N/A ASN 326.A N THR 323.A O no hydrogen 3.204 N/A ASN 326.A ND2 LEU 304.A O no hydrogen 2.595 N/A VAL 327.A N HIS 322.A O no hydrogen 3.186 N/A LEU 328.A N ILE 307.A O no hydrogen 2.765 N/A LEU 329.A N THR 320.A O no hydrogen 2.696 N/A LEU 330.A N ALA 309.A O no hydrogen 2.878 N/A GLU 332.A N GLY 312.A O no hydrogen 2.988 N/A TYR 333.A N PRO 331.A O no hydrogen 2.902 N/A TYR 333.A OH ARG 317.A O no hydrogen 2.307 N/A SER 334.A N ASP 314.A OD1 no hydrogen 3.204 N/A SER 334.A OG ASP 314.A OD2 no hydrogen 3.228 N/A SER 335.A OG GLU 337.A OE2 no hydrogen 3.083 N/A LYS 336.A NZ GLU 273.A OE2 no hydrogen 2.464 N/A GLU 337.A N GLU 337.A OE2 no hydrogen 2.427 N/A LYS 338.A N SER 335.A O no hydrogen 2.858 N/A LYS 338.A NZ ASP 314.A OD1 no hydrogen 3.075 N/A LYS 338.A NZ THR 315.A O no hydrogen 2.651 N/A LYS 338.A NZ GLU 316.A OE1 no hydrogen 3.092 N/A LYS 338.A NZ GLU 316.A OE2 no hydrogen 2.796 N/A LEU 339.A N SER 335.A O no hydrogen 2.711 N/A LYS 340.A N LYS 336.A O no hydrogen 2.955 N/A GLU 341.A N GLU 337.A O no hydrogen 3.219 N/A ARG 342.A N LYS 338.A O no hydrogen 3.010 N/A ARG 342.A NE GLU 341.A OE2 no hydrogen 2.693 N/A ARG 342.A NH1 GLU 316.A O no hydrogen 2.898 N/A ARG 342.A NH2 GLU 341.A OE1 no hydrogen 3.487 N/A LEU 343.A N LEU 339.A O no hydrogen 2.863 N/A LEU 344.A N LYS 340.A O no hydrogen 3.171 N/A LYS 345.A N GLU 341.A O no hydrogen 3.159 N/A ALA 346.A N ARG 342.A O no hydrogen 3.106 N/A ALA 346.A N LEU 343.A O no hydrogen 3.178 N/A ILE 347.A N LEU 343.A O no hydrogen 3.007 N/A THR 348.A N LEU 344.A O no hydrogen 2.892 N/A TYR 349.A N LYS 345.A O no hydrogen 3.083 N/A ALA 350.A N ALA 346.A O no hydrogen 3.369 N/A