Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 1c8m_2.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 3.A NH1 ASP 18.A OD1 no hydrogen 2.734 N/A ARG 3.A NH2 ASP 18.A OD1 no hydrogen 2.906 N/A ILE 5.A N SER 16.A O no hydrogen 3.003 N/A GLN 6.A NE2 THR 8.A OG1 no hydrogen 2.839 N/A ILE 7.A N ILE 14.A O no hydrogen 2.822 N/A THR 8.A OG1 THR 13.A OG1 no hydrogen 2.870 N/A ARG 9.A N SER 12.A O no hydrogen 2.860 N/A ARG 9.A NE THR 98.A OG1 no hydrogen 3.102 N/A ARG 9.A NH1 THR 8.A O no hydrogen 3.075 N/A ARG 9.A NH2 THR 98.A OG1 no hydrogen 3.059 N/A SER 12.A N ARG 9.A O no hydrogen 2.922 N/A SER 12.A OG ARG 9.A O no hydrogen 2.661 N/A THR 13.A OG1 THR 8.A OG1 no hydrogen 2.870 N/A ILE 14.A N ILE 7.A O no hydrogen 2.777 N/A SER 16.A N ILE 5.A O no hydrogen 3.223 N/A SER 16.A OG ASN 187.A OD1 no hydrogen 3.045 N/A SER 16.A OG SER 188.A OG no hydrogen 2.816 N/A VAL 19.A N ARG 3.A O no hydrogen 3.174 N/A VAL 23.A N THR 190.A O no hydrogen 2.980 N/A GLY 25.A N ILE 192.A O no hydrogen 2.779 N/A GLY 27.A N VAL 24.A O no hydrogen 2.899 N/A VAL 28.A N GLY 25.A O no hydrogen 3.245 N/A HIS 31.A ND1 TRP 29.A O no hydrogen 3.081 N/A LEU 33.A N GLU 241.A OE1 no hydrogen 2.869 N/A ASP 37.A N THR 34.A O no hydrogen 3.161 N/A ALA 38.A N THR 34.A O no hydrogen 2.996 N/A THR 45.A N PHE 242.A O no hydrogen 2.888 N/A SER 50.A N PRO 47.A O no hydrogen 3.320 N/A SER 51.A N ASP 48.A O no hydrogen 3.114 N/A SER 51.A OG ASP 48.A O no hydrogen 3.473 N/A SER 51.A OG ASN 52.A OD1 no hydrogen 3.110 N/A ASN 52.A N ASP 48.A O no hydrogen 2.853 N/A ARG 53.A NH1 THR 49.A O no hydrogen 3.187 N/A PHE 54.A N SER 12.A OG no hydrogen 2.906 N/A TYR 55.A N ILE 235.A O no hydrogen 2.757 N/A THR 56.A OG1 SER 234.A OG no hydrogen 2.858 N/A LEU 57.A N VAL 233.A O no hydrogen 2.917 N/A SER 59.A OG THR 232.A OG1 no hydrogen 2.797 N/A LYS 60.A N ILE 231.A O no hydrogen 2.900 N/A LYS 60.A NZ ALA 143.A O no hydrogen 2.938 N/A LYS 60.A NZ GLU 146.A OE2 no hydrogen 3.519 N/A TRP 62.A N VAL 229.A O no hydrogen 2.968 N/A ASN 63.A N SER 66.A OG no hydrogen 2.896 N/A THR 65.A N ASN 63.A OD1 no hydrogen 3.127 N/A THR 65.A OG1 ASN 63.A OD1 no hydrogen 2.998 N/A SER 66.A N ASN 63.A O no hydrogen 3.038 N/A SER 66.A OG ASN 63.A O no hydrogen 3.058 N/A SER 66.A OG ASN 63.A OD1 no hydrogen 3.457 N/A TRP 69.A N ILE 214.A O no hydrogen 2.940 N/A TRP 70.A N ARG 145.A O no hydrogen 3.084 N/A TRP 71.A N LEU 212.A O no hydrogen 2.902 N/A TRP 71.A NE1 GLU 142.A O no hydrogen 3.231 N/A LYS 72.A NZ HIS 121.A O no hydrogen 3.051 N/A LYS 72.A NZ SER 211.A OG no hydrogen 2.791 N/A LEU 73.A N TRP 210.A O no hydrogen 2.808 N/A ASP 75.A N ASN 208.A OD1 no hydrogen 3.294 N/A ALA 76.A N LYS 72.A O no hydrogen 2.809 N/A LEU 77.A N PRO 74.A O no hydrogen 2.853 N/A LYS 78.A N ASP 75.A O no hydrogen 3.006 N/A LYS 78.A NZ ASP 75.A OD1 no hydrogen 3.078 N/A LYS 78.A NZ HIS 139.A O no hydrogen 3.205 N/A MET 80.A N LEU 77.A O no hydrogen 3.184 N/A GLY 84.A N MET 80.A O no hydrogen 2.977 N/A GLU 85.A N GLY 81.A O no hydrogen 3.211 N/A ASN 86.A N ILE 82.A O no hydrogen 2.977 N/A ASN 86.A ND2 ILE 82.A O no hydrogen 2.893 N/A MET 87.A N PHE 83.A O no hydrogen 3.133 N/A PHE 88.A N GLU 85.A O no hydrogen 3.104 N/A TYR 89.A N GLU 85.A O no hydrogen 3.175 N/A HIS 90.A ND1 ASN 86.A O no hydrogen 2.867 N/A PHE 91.A N GLY 244.A O no hydrogen 3.023 N/A LEU 92.A N SER 243.A O no hydrogen 3.033 N/A GLY 93.A N ASP 202.A O no hydrogen 2.870 N/A ARG 94.A N GLU 241.A O no hydrogen 2.920 N/A ARG 94.A NH1 PRO 200.A O no hydrogen 2.928 N/A ARG 94.A NH2 HIS 31.A O no hydrogen 3.389 N/A SER 95.A OG GLY 96.A O no hydrogen 2.871 N/A GLY 96.A N MET 238.A O no hydrogen 2.927 N/A TYR 97.A N VAL 193.A O no hydrogen 2.987 N/A THR 98.A N SER 236.A O no hydrogen 2.844 N/A VAL 99.A N LEU 191.A O no hydrogen 2.736 N/A HIS 100.A N SER 234.A O no hydrogen 2.892 N/A HIS 100.A ND1 THR 190.A OG1 no hydrogen 2.806 N/A VAL 101.A N ALA 189.A O no hydrogen 2.944 N/A GLN 102.A N THR 232.A O no hydrogen 2.690 N/A GLN 102.A NE2 HIS 100.A O no hydrogen 3.086 N/A GLN 102.A NE2 SER 234.A OG no hydrogen 2.990 N/A CYS 103.A N ASN 187.A O no hydrogen 2.893 N/A CYS 103.A SG PRO 230.A O no hydrogen 3.526 N/A SER 106.A OG HIS 109.A ND1 no hydrogen 2.697 N/A PHE 108.A N SER 106.A OG no hydrogen 2.999 N/A HIS 109.A N SER 106.A O no hydrogen 3.217 N/A HIS 109.A ND1 SER 106.A OG no hydrogen 2.697 N/A GLN 110.A N GLN 221.A O no hydrogen 2.924 N/A GLN 110.A NE2 GLN 221.A OE1 no hydrogen 2.958 N/A THR 112.A N CYS 218.A O no hydrogen 2.941 N/A THR 112.A OG1 ASN 182.A OD1 no hydrogen 3.105 N/A LEU 113.A N ILE 181.A O no hydrogen 2.902 N/A LEU 114.A N ILE 215.A O no hydrogen 2.858 N/A VAL 115.A N GLN 179.A O no hydrogen 2.869 N/A VAL 116.A N VAL 213.A O no hydrogen 2.838 N/A MET 117.A N PRO 177.A O no hydrogen 3.016 N/A ILE 118.A N SER 211.A O no hydrogen 2.899 N/A GLU 120.A N ASN 209.A O no hydrogen 2.944 N/A HIS 121.A NE2 ASN 164.A O no hydrogen 2.806 N/A GLN 122.A N GLU 120.A O no hydrogen 3.003 N/A ALA 124.A N PHE 165.A O no hydrogen 2.920 N/A THR 125.A OG1 VAL 131.A O no hydrogen 2.726 N/A LYS 128.A NZ GLU 154.A O no hydrogen 3.062 N/A LYS 128.A NZ GLN 156.A O no hydrogen 3.321 N/A VAL 131.A N LYS 128.A O no hydrogen 3.502 N/A GLY 134.A N LYS 155.A O no hydrogen 2.859 N/A TYR 135.A OH VAL 205.A O no hydrogen 2.754 N/A TYR 137.A N GLY 134.A O no hydrogen 2.928 N/A THR 138.A N GLY 134.A O no hydrogen 3.385 N/A THR 138.A OG1 TYR 135.A O no hydrogen 3.416 N/A THR 138.A OG1 HIS 139.A ND1 no hydrogen 3.252 N/A HIS 139.A ND1 TYR 135.A O no hydrogen 2.831 N/A GLY 141.A N ASP 75.A OD2 no hydrogen 2.912 N/A GLY 144.A N GLY 141.A O no hydrogen 3.068 N/A ARG 145.A N TRP 70.A O no hydrogen 2.915 N/A ARG 145.A NE ASP 159.A OD1 no hydrogen 3.420 N/A ARG 145.A NH2 ASP 159.A OD1 no hydrogen 3.551 N/A VAL 147.A N GLY 68.A O no hydrogen 2.971 N/A GLY 148.A N ASP 159.A OD2 no hydrogen 2.854 N/A THR 149.A OG1 GLU 146.A O no hydrogen 3.302 N/A LYS 155.A NZ ASN 132.A O no hydrogen 3.179 N/A SER 158.A N ALA 124.A O no hydrogen 2.678 N/A SER 158.A OG ASP 160.A OD2 no hydrogen 3.502 N/A ASP 160.A N SER 158.A OG no hydrogen 3.141 N/A ASN 161.A ND2 LYS 67.A O no hydrogen 2.867 N/A LEU 163.A N ASP 160.A O no hydrogen 3.116 N/A ASN 164.A N ASN 161.A O no hydrogen 3.052 N/A ASN 164.A ND2 ASN 161.A O no hydrogen 3.631 N/A PHE 165.A N ASP 160.A O no hydrogen 3.194 N/A ASP 166.A N LEU 163.A O no hydrogen 2.995 N/A GLY 167.A N LEU 163.A O no hydrogen 2.951 N/A THR 168.A N LEU 163.A O no hydrogen 3.320 N/A THR 168.A OG1 ASN 164.A OD1 no hydrogen 3.169 N/A THR 168.A OG1 ASP 166.A OD1 no hydrogen 2.622 N/A LEU 170.A N TRP 162.A O no hydrogen 3.047 N/A ASN 172.A N LEU 169.A O no hydrogen 3.004 N/A LEU 173.A N LEU 170.A O no hydrogen 2.973 N/A ILE 175.A N ASN 172.A O no hydrogen 3.234 N/A PHE 176.A N LEU 173.A O no hydrogen 3.049 N/A HIS 178.A ND1 PHE 176.A O no hydrogen 3.084 N/A GLN 179.A N VAL 115.A O no hydrogen 2.989 N/A GLN 179.A NE2 ALA 20.A O no hydrogen 2.920 N/A GLN 179.A NE2 ASN 21.A O no hydrogen 3.604 N/A ILE 181.A N LEU 113.A O no hydrogen 2.831 N/A ASN 182.A N ASN 186.A OD1 no hydrogen 3.003 N/A LEU 183.A N GLY 111.A O no hydrogen 2.973 N/A SER 185.A N ASN 182.A O no hydrogen 2.761 N/A ASN 186.A N ASN 182.A O no hydrogen 3.076 N/A ASN 186.A ND2 PHE 180.A O no hydrogen 2.923 N/A ASN 186.A ND2 SER 188.A O no hydrogen 3.020 N/A ASN 187.A N ASP 18.A O no hydrogen 2.934 N/A SER 188.A OG SER 16.A OG no hydrogen 2.816 N/A ALA 189.A N VAL 101.A O no hydrogen 2.910 N/A THR 190.A N GLN 179.A OE1 no hydrogen 2.826 N/A THR 190.A OG1 HIS 100.A ND1 no hydrogen 2.806 N/A LEU 191.A N VAL 99.A O no hydrogen 2.917 N/A ILE 192.A N VAL 23.A O no hydrogen 2.738 N/A VAL 193.A N TYR 97.A O no hydrogen 2.898 N/A ASN 197.A ND2 TYR 195.A OH no hydrogen 2.946 N/A ASN 197.A ND2 ASP 202.A OD2 no hydrogen 3.182 N/A ALA 198.A N ASN 197.A OD1 no hydrogen 2.824 N/A ASP 202.A N GLY 93.A O no hydrogen 3.148 N/A SER 203.A N ASP 202.A OD1 no hydrogen 2.734 N/A VAL 205.A N SER 203.A OG no hydrogen 3.340 N/A ARG 206.A N SER 203.A OG no hydrogen 3.127 N/A HIS 207.A N SER 203.A O no hydrogen 3.250 N/A TRP 210.A N LEU 73.A O no hydrogen 3.462 N/A SER 211.A N ILE 118.A O no hydrogen 2.913 N/A LEU 212.A N TRP 71.A O no hydrogen 2.758 N/A VAL 213.A N VAL 116.A O no hydrogen 2.860 N/A ILE 214.A N TRP 69.A O no hydrogen 2.947 N/A ILE 215.A N LEU 114.A O no hydrogen 3.063 N/A CYS 218.A N THR 112.A O no hydrogen 3.323 N/A GLN 219.A NE2 SER 64.A O no hydrogen 2.884 N/A GLN 221.A N GLN 110.A O no hydrogen 2.919 N/A ASN 224.A N SER 222.A OG no hydrogen 3.122 N/A ASN 224.A ND2 ASN 227.A OD1 no hydrogen 3.679 N/A ASN 227.A N ASN 224.A O no hydrogen 3.280 N/A ASN 227.A ND2 ILE 228.A O no hydrogen 3.556 N/A ILE 231.A N LYS 60.A O no hydrogen 2.732 N/A THR 232.A N GLN 102.A O no hydrogen 2.886 N/A THR 232.A OG1 SER 59.A OG no hydrogen 2.797 N/A SER 234.A N HIS 100.A O no hydrogen 2.992 N/A SER 234.A OG THR 56.A OG1 no hydrogen 2.858 N/A ILE 235.A N TYR 55.A O no hydrogen 2.880 N/A SER 236.A N THR 98.A O no hydrogen 2.878 N/A SER 236.A OG PRO 237.A O no hydrogen 3.071 N/A MET 238.A N GLY 96.A O no hydrogen 2.859 N/A CYS 239.A SG PRO 30.A O no hydrogen 3.613 N/A ALA 240.A N ASN 52.A OD1 no hydrogen 3.320 N/A GLU 241.A N ARG 94.A O no hydrogen 2.983 N/A PHE 242.A N THR 45.A O no hydrogen 3.010 N/A SER 243.A N LEU 92.A O no hydrogen 2.920 N/A SER 243.A OG ASP 42.A OD1 no hydrogen 3.055 N/A GLY 244.A N ASP 42.A OD1 no hydrogen 2.970 N/A ARG 246.A N TYR 89.A O no hydrogen 2.890 N/A ARG 246.A NH1 PHE 88.A O no hydrogen 3.129 N/A ARG 246.A NH1 ALA 247.A O no hydrogen 2.900 N/A LYS 248.A NZ GLU 85.A OE1 no hydrogen 2.872 N/A THR 249.A N PHE 88.A O no hydrogen 2.972 N/A THR 249.A OG1 PHE 88.A O no hydrogen 3.289 N/A