Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 1cko_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 3.A OG1 VAL 22.A O no hydrogen 2.600 N/A THR 3.A OG1 SER 25.A OG no hydrogen 3.073 N/A GLU 5.A N LYS 20.A O no hydrogen 2.845 N/A ALA 7.A N LEU 18.A O no hydrogen 3.246 N/A LEU 9.A N ILE 16.A O no hydrogen 2.641 N/A LEU 11.A N LEU 14.A O no hydrogen 2.619 N/A LEU 14.A N LEU 11.A O no hydrogen 2.694 N/A ILE 16.A N LEU 9.A O no hydrogen 2.536 N/A LEU 18.A N ALA 7.A O no hydrogen 2.854 N/A LYS 20.A NZ GLU 5.A OE2 no hydrogen 3.166 N/A VAL 21.A N VAL 100.A O no hydrogen 2.868 N/A VAL 22.A N THR 3.A O no hydrogen 2.582 N/A SER 25.A OG ASN 1.A O no hydrogen 2.421 N/A SER 25.A OG THR 3.A OG1 no hydrogen 3.073 N/A ASP 27.A N GLY 23.A O no hydrogen 3.348 N/A ASP 28.A N GLU 24.A O no hydrogen 2.983 N/A ASP 28.A N SER 25.A O no hydrogen 3.216 N/A ILE 29.A N SER 25.A O no hydrogen 3.032 N/A VAL 30.A N ARG 26.A O no hydrogen 2.845 N/A ALA 31.A N ASP 27.A O no hydrogen 2.742 N/A LYS 32.A N ASP 28.A O no hydrogen 2.587 N/A LYS 32.A NZ ARG 84.A O no hydrogen 2.609 N/A MET 33.A N ILE 29.A O no hydrogen 3.104 N/A LYS 34.A N VAL 30.A O no hydrogen 2.996 N/A ASP 35.A N ALA 31.A O no hydrogen 3.080 N/A LEU 36.A N LYS 32.A O no hydrogen 2.957 N/A ALA 37.A N MET 33.A O no hydrogen 3.170 N/A MET 38.A N ASP 35.A O no hydrogen 3.172 N/A ASP 39.A N LYS 34.A O no hydrogen 3.320 N/A HIS 41.A N ASP 39.A O no hydrogen 2.649 N/A ARG 45.A NE ASP 39.A OD1 no hydrogen 3.071 N/A ARG 45.A NE ASP 39.A OD2 no hydrogen 3.535 N/A ARG 45.A NH2 ASP 39.A OD1 no hydrogen 3.195 N/A GLY 48.A N LEU 46.A O no hydrogen 2.659 N/A ASN 50.A N GLY 217.A O no hydrogen 2.497 N/A ASN 50.A ND2 PRO 49.A O no hydrogen 3.463 N/A VAL 52.A N LEU 222.A O no hydrogen 2.549 N/A ILE 54.A N LYS 224.A O no hydrogen 2.907 N/A GLU 55.A N ASP 58.A OD2 no hydrogen 2.908 N/A ARG 56.A N GLU 306.A OE1 no hydrogen 3.234 N/A ARG 56.A N GLU 306.A OE2 no hydrogen 3.225 N/A ARG 56.A NH1 GLU 312.A OE1 no hydrogen 2.757 N/A ARG 56.A NH2 GLU 306.A O no hydrogen 2.812 N/A ARG 56.A NH2 GLU 312.A OE1 no hydrogen 2.879 N/A ARG 56.A NH2 GLU 312.A OE2 no hydrogen 3.446 N/A LYS 57.A NZ ASP 58.A OD1 no hydrogen 2.834 N/A ASP 58.A N GLU 55.A O no hydrogen 3.046 N/A PHE 59.A N ARG 56.A O no hydrogen 2.974 N/A LYS 61.A NZ ASN 221.A OD1 no hydrogen 2.876 N/A LEU 62.A N ASP 58.A O no hydrogen 2.827 N/A LYS 63.A N PHE 59.A O no hydrogen 2.549 N/A GLN 64.A N GLU 60.A O no hydrogen 3.093 N/A ASN 65.A N LYS 61.A O no hydrogen 3.446 N/A VAL 68.A N MET 208.A O no hydrogen 2.632 N/A VAL 69.A N ILE 181.A O no hydrogen 2.551 N/A SER 70.A N ILE 206.A O no hydrogen 2.757 N/A SER 70.A OG GLU 71.A O no hydrogen 3.569 N/A LYS 72.A N GLY 204.A O no hydrogen 2.525 N/A LYS 72.A NZ ASP 203.A OD2 no hydrogen 2.948 N/A THR 73.A OG1 GLU 71.A OE1 no hydrogen 3.202 N/A ASP 74.A N HIS 201.A O no hydrogen 2.545 N/A ILE 76.A N LEU 122.A O no hydrogen 2.645 N/A ARG 77.A NE ASP 119.A OD1 no hydrogen 3.002 N/A ARG 77.A NH1 PRO 49.A O no hydrogen 3.344 N/A ARG 77.A NH2 PRO 49.A O no hydrogen 3.321 N/A ARG 77.A NH2 ASP 119.A OD1 no hydrogen 3.137 N/A ARG 77.A NH2 ASP 119.A OD2 no hydrogen 2.864 N/A PHE 78.A N GLY 120.A O no hydrogen 3.381 N/A MET 79.A N ILE 94.A O no hydrogen 2.862 N/A MET 80.A N PHE 118.A O no hydrogen 2.993 N/A PHE 81.A N THR 92.A O no hydrogen 2.528 N/A PHE 82.A N SER 116.A O no hydrogen 2.842 N/A THR 83.A N VAL 90.A O no hydrogen 2.775 N/A THR 83.A OG1 ARG 84.A O no hydrogen 3.084 N/A VAL 85.A N PHE 88.A O no hydrogen 2.586 N/A PHE 88.A N VAL 85.A O no hydrogen 2.522 N/A VAL 90.A N THR 83.A O no hydrogen 2.646 N/A CYS 91.A SG LEU 103.A O no hydrogen 3.119 N/A THR 92.A N PHE 81.A O no hydrogen 2.525 N/A THR 92.A OG1 PHE 81.A O no hydrogen 3.100 N/A ILE 93.A N TYR 101.A O no hydrogen 2.862 N/A ILE 94.A N MET 79.A O no hydrogen 2.607 N/A ASP 95.A N THR 99.A O no hydrogen 3.000 N/A MET 98.A N ASP 95.A O no hydrogen 2.932 N/A TYR 101.A N ILE 93.A O no hydrogen 3.162 N/A LEU 102.A N HIS 19.A O no hydrogen 2.940 N/A LEU 103.A N CYS 91.A O no hydrogen 3.065 N/A LYS 106.A N ASP 171.A OD1 no hydrogen 3.298 N/A ASN 107.A ND2 LYS 166.A O no hydrogen 2.648 N/A ILE 108.A N LYS 106.A O no hydrogen 2.800 N/A LEU 112.A N PRO 109.A O no hydrogen 2.627 N/A PHE 113.A N ARG 110.A O no hydrogen 3.219 N/A GLN 114.A N VAL 111.A O no hydrogen 2.604 N/A GLY 115.A N LEU 112.A O no hydrogen 2.860 N/A SER 116.A N PHE 82.A O no hydrogen 3.235 N/A SER 116.A OG LEU 112.A O no hydrogen 2.493 N/A ILE 117.A N VAL 140.A O no hydrogen 2.749 N/A PHE 118.A N MET 80.A O no hydrogen 3.191 N/A ASP 119.A N ASP 137.A O no hydrogen 2.905 N/A GLU 121.A N VAL 134.A O no hydrogen 2.798 N/A LEU 122.A N ILE 76.A O no hydrogen 2.673 N/A CYS 123.A N ALA 132.A O no hydrogen 2.886 N/A CYS 123.A SG GLU 121.A O no hydrogen 3.948 N/A CYS 123.A SG ALA 132.A O no hydrogen 3.713 N/A ASP 125.A N LYS 130.A O no hydrogen 2.500 N/A ILE 126.A N ILE 199.A O no hydrogen 2.830 N/A VAL 127.A N ASP 125.A OD1 no hydrogen 2.847 N/A LYS 129.A N ASP 125.A O no hydrogen 2.697 N/A LYS 130.A N ASP 125.A O no hydrogen 3.243 N/A LYS 130.A NZ PRO 169.A O no hydrogen 2.977 N/A ALA 132.A N CYS 123.A O no hydrogen 3.062 N/A PHE 133.A N ILE 174.A O no hydrogen 2.846 N/A VAL 134.A N GLU 121.A O no hydrogen 2.899 N/A LEU 135.A N ARG 176.A O no hydrogen 2.604 N/A PHE 136.A N ASP 119.A O no hydrogen 2.623 N/A ASP 137.A N ASP 119.A O no hydrogen 2.942 N/A ALA 138.A N ASP 137.A OD1 no hydrogen 2.865 N/A VAL 139.A N ILE 117.A O no hydrogen 2.630 N/A VAL 140.A N ILE 117.A O no hydrogen 3.209 N/A VAL 141.A N VAL 144.A O no hydrogen 2.742 N/A SER 142.A N SER 116.A OG no hydrogen 2.895 N/A SER 142.A OG VAL 111.A O no hydrogen 3.539 N/A GLY 143.A N GLY 115.A O no hydrogen 2.944 N/A VAL 144.A N VAL 141.A O no hydrogen 2.526 N/A THR 145.A OG1 GLY 143.A O no hydrogen 3.361 N/A VAL 146.A N VAL 139.A O no hydrogen 3.016 N/A MET 149.A N VAL 146.A O no hydrogen 3.002 N/A ASP 150.A N SER 153.A OG no hydrogen 3.267 N/A SER 153.A OG ASP 150.A OD1 no hydrogen 2.932 N/A ARG 154.A N ASP 150.A O no hydrogen 2.996 N/A ARG 154.A NH1 ASP 137.A OD1 no hydrogen 2.714 N/A ARG 154.A NH2 GLU 212.A O no hydrogen 2.547 N/A PHE 155.A N LEU 151.A O no hydrogen 2.640 N/A PHE 156.A N ALA 152.A O no hydrogen 2.724 N/A ALA 157.A N SER 153.A O no hydrogen 2.713 N/A MET 158.A N ARG 154.A O no hydrogen 2.825 N/A LYS 159.A N PHE 155.A O no hydrogen 2.656 N/A ARG 160.A N PHE 156.A O no hydrogen 2.746 N/A SER 161.A N ALA 157.A O no hydrogen 3.417 N/A SER 161.A OG ALA 157.A O no hydrogen 3.471 N/A SER 161.A OG MET 158.A O no hydrogen 2.554 N/A LEU 162.A N MET 158.A O no hydrogen 3.249 N/A LYS 163.A N ARG 160.A O no hydrogen 2.974 N/A PHE 165.A N LEU 162.A O no hydrogen 3.060 N/A VAL 168.A N ASP 171.A OD2 no hydrogen 3.285 N/A ASP 171.A N VAL 168.A O no hydrogen 2.620 N/A ILE 174.A N PHE 131.A O no hydrogen 2.801 N/A ARG 176.A N PHE 133.A O no hydrogen 2.706 N/A ARG 176.A NE TYR 200.A OH no hydrogen 3.180 N/A LYS 178.A N LEU 135.A O no hydrogen 2.610 N/A TRP 180.A NE1 PHE 136.A O no hydrogen 2.821 N/A ILE 181.A N VAL 69.A O no hydrogen 2.892 N/A LEU 183.A N TYR 67.A O no hydrogen 2.983 N/A ILE 188.A N HIS 185.A O no hydrogen 2.745 N/A ILE 189.A N HIS 185.A O no hydrogen 3.079 N/A LYS 190.A N PRO 186.A O no hydrogen 2.936 N/A LYS 190.A NZ ASP 311.A OD1 no hydrogen 2.920 N/A ASP 191.A N THR 187.A O no hydrogen 3.214 N/A HIS 192.A N ILE 188.A O no hydrogen 2.577 N/A LEU 193.A N ILE 189.A O no hydrogen 2.660 N/A LYS 194.A N LYS 190.A O no hydrogen 2.787 N/A LYS 195.A N ASP 191.A O no hydrogen 2.600 N/A ALA 196.A N HIS 192.A O no hydrogen 2.623 N/A ASN 197.A N LEU 193.A O no hydrogen 2.736 N/A ASN 197.A ND2 LEU 193.A O no hydrogen 2.778 N/A ALA 198.A N LYS 195.A O no hydrogen 3.125 N/A ILE 199.A N ALA 196.A O no hydrogen 2.896 N/A TYR 200.A N ALA 196.A O no hydrogen 2.964 N/A THR 202.A OG1 ASN 197.A OD1 no hydrogen 2.723 N/A ASP 203.A N LYS 72.A O no hydrogen 2.702 N/A LEU 205.A N LEU 225.A O no hydrogen 2.767 N/A ILE 206.A N SER 70.A O no hydrogen 2.414 N/A ILE 207.A N PHE 223.A O no hydrogen 3.218 N/A MET 208.A N VAL 68.A O no hydrogen 2.997 N/A SER 209.A OG ASP 211.A OD1 no hydrogen 2.840 N/A VAL 210.A N LYS 66.A O no hydrogen 2.567 N/A ASP 211.A N SER 209.A OG no hydrogen 2.953 N/A GLU 212.A N SER 209.A OG no hydrogen 3.214 N/A VAL 214.A N SER 147.A O no hydrogen 2.845 N/A TYR 216.A OH ALA 37.A O no hydrogen 2.452 N/A GLY 217.A N GLY 48.A O no hydrogen 2.793 N/A ASN 219.A N ASN 50.A O no hydrogen 2.785 N/A ASN 221.A N ASN 219.A OD1 no hydrogen 2.890 N/A LEU 222.A N ASN 219.A O no hydrogen 2.736 N/A PHE 223.A N ILE 207.A O no hydrogen 2.979 N/A LYS 224.A N VAL 52.A O no hydrogen 2.650 N/A LEU 225.A N LEU 205.A O no hydrogen 2.886 N/A LYS 226.A NZ HIS 230.A O no hydrogen 3.504 N/A THR 229.A N PRO 227.A O no hydrogen 3.011 N/A ILE 233.A N CYS 272.A O no hydrogen 3.158 N/A PHE 235.A N VAL 270.A O no hydrogen 3.100 N/A ILE 236.A N GLY 245.A O no hydrogen 2.563 N/A ILE 237.A N SER 268.A O no hydrogen 2.708 N/A MET 238.A N THR 243.A O no hydrogen 2.567 N/A SER 239.A OG MET 238.A O no hydrogen 3.237 N/A SER 239.A OG THR 243.A OG1 no hydrogen 3.123 N/A GLY 242.A N SER 239.A O no hydrogen 2.547 N/A THR 243.A OG1 SER 239.A OG no hydrogen 3.123 N/A THR 243.A OG1 ASP 241.A OD1 no hydrogen 2.832 N/A ILE 244.A N GLY 258.A O no hydrogen 2.583 N/A GLY 245.A N ILE 236.A O no hydrogen 2.603 N/A ILE 246.A N VAL 255.A O no hydrogen 2.880 N/A PHE 247.A N ASN 292.A O no hydrogen 3.165 N/A ASP 248.A N LYS 253.A O no hydrogen 2.641 N/A LEU 251.A N ASP 248.A O no hydrogen 3.164 N/A LEU 251.A N ASP 248.A OD1 no hydrogen 2.887 N/A ARG 252.A N ASP 248.A O no hydrogen 2.460 N/A VAL 255.A N ILE 246.A O no hydrogen 2.727 N/A VAL 257.A N ILE 244.A O no hydrogen 2.496 N/A GLY 258.A N ILE 244.A O no hydrogen 3.147 N/A LEU 260.A N GLY 242.A O no hydrogen 2.541 N/A TYR 264.A N GLU 240.A O no hydrogen 2.685 N/A TYR 264.A OH ASP 261.A O no hydrogen 2.624 N/A ASN 265.A ND2 SER 268.A OG no hydrogen 3.052 N/A GLY 267.A N ILE 237.A O no hydrogen 2.741 N/A SER 268.A N ASN 265.A O no hydrogen 2.748 N/A SER 268.A OG ASN 265.A O no hydrogen 2.571 N/A VAL 270.A N PHE 235.A O no hydrogen 2.970 N/A GLU 271.A N GLN 283.A O no hydrogen 2.612 N/A CYS 272.A N ILE 233.A O no hydrogen 2.785 N/A CYS 272.A SG VAL 270.A O no hydrogen 3.426 N/A GLY 273.A N LYS 280.A O no hydrogen 2.747 N/A ALA 275.A N THR 278.A O no hydrogen 2.679 N/A THR 278.A N ALA 275.A O no hydrogen 2.492 N/A THR 278.A OG1 ALA 275.A O no hydrogen 2.995 N/A LYS 280.A N GLY 273.A O no hydrogen 2.674 N/A ILE 282.A N GLU 271.A O no hydrogen 2.670 N/A GLN 283.A N GLU 271.A O no hydrogen 3.194 N/A GLN 283.A NE2 GLU 271.A OE1 no hydrogen 2.915 N/A ARG 285.A N ILE 269.A O no hydrogen 3.056 N/A LYS 288.A N ARG 285.A O no hydrogen 2.985 N/A GLN 290.A NE2 ASN 289.A OD1 no hydrogen 3.640 N/A ASN 292.A N ASP 234.A O no hydrogen 3.033 N/A ARG 294.A N PHE 247.A O no hydrogen 2.611 N/A ARG 294.A NH2 ASP 248.A OD2 no hydrogen 3.061 N/A THR 296.A OG1 ASP 293.A OD1 no hydrogen 3.239 N/A TYR 297.A N ASP 293.A O no hydrogen 3.257 N/A GLU 298.A N ARG 294.A O no hydrogen 2.894 N/A LYS 299.A N LEU 295.A O no hydrogen 2.601 N/A LYS 299.A NZ GLU 55.A OE1 no hydrogen 3.511 N/A THR 300.A N THR 296.A O no hydrogen 2.774 N/A THR 300.A OG1 THR 296.A O no hydrogen 2.914 N/A LEU 301.A N TYR 297.A O no hydrogen 2.962 N/A LEU 302.A N GLU 298.A O no hydrogen 2.794 N/A ASN 303.A N LYS 299.A O no hydrogen 2.602 N/A ILE 304.A N THR 300.A O no hydrogen 2.781 N/A GLU 305.A N LEU 301.A O no hydrogen 2.698 N/A GLU 306.A N LEU 302.A O no hydrogen 3.102 N/A THR 309.A N GLU 312.A OE2 no hydrogen 3.058 N/A THR 309.A OG1 GLU 312.A OE2 no hydrogen 3.381 N/A GLU 312.A N THR 309.A OG1 no hydrogen 3.064 N/A LEU 313.A N THR 309.A O no hydrogen 2.915 N/A LEU 314.A N ILE 310.A O no hydrogen 2.655 N/A ASP 315.A N LEU 313.A O no hydrogen 2.686 N/A LEU 316.A N LEU 313.A O no hydrogen 3.206 N/A