Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 1cvi_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LYS 1.A N GLU 289.A OE2 no hydrogen 2.885 N/A LYS 1.A NZ GLU 296.A OE2 no hydrogen 3.338 N/A LYS 4.A N LEU 286.A O no hydrogen 2.813 N/A LYS 4.A NZ GLU 2.A OE2 no hydrogen 3.374 N/A PHE 5.A N LEU 286.A O no hydrogen 3.407 N/A VAL 6.A N LYS 250.A O no hydrogen 2.993 N/A THR 7.A N THR 284.A O no hydrogen 3.155 N/A LEU 8.A N ILE 252.A O no hydrogen 3.044 N/A VAL 9.A N HIS 282.A O no hydrogen 3.270 N/A PHE 10.A N TYR 254.A O no hydrogen 3.311 N/A ARG 11.A N SER 280.A O no hydrogen 3.034 N/A HIS 12.A N ALA 256.A O no hydrogen 3.248 N/A HIS 12.A ND1 GLY 13.A O no hydrogen 2.775 N/A GLY 13.A N SER 83.A OG no hydrogen 2.999 N/A ASP 14.A N GLN 45.A OE1 no hydrogen 2.531 N/A SER 16.A N GLN 37.A O no hydrogen 2.878 N/A SER 16.A OG PRO 17.A O no hydrogen 3.251 N/A SER 16.A OG GLY 34.A O no hydrogen 2.600 N/A THR 20.A OG1 PHE 21.A O no hydrogen 3.466 N/A THR 20.A OG1 ASP 24.A OD2 no hydrogen 2.916 N/A THR 23.A N SER 163.A O no hydrogen 3.164 N/A THR 23.A OG1 LEU 162.A O no hydrogen 3.025 N/A THR 23.A OG1 SER 163.A O no hydrogen 2.455 N/A ASP 24.A N PHE 21.A O no hydrogen 2.943 N/A SER 30.A N LYS 27.A O no hydrogen 2.905 N/A SER 30.A OG LYS 27.A O no hydrogen 2.905 N/A TRP 31.A N GLU 28.A O no hydrogen 2.723 N/A GLY 34.A N TRP 31.A O no hydrogen 3.120 N/A PHE 35.A N GLU 28.A OE2 no hydrogen 2.765 N/A GLY 36.A N PRO 17.A O no hydrogen 2.824 N/A GLN 37.A NE2 ASP 78.A OD2 no hydrogen 3.387 N/A THR 39.A N ASP 14.A O no hydrogen 3.029 N/A THR 39.A OG1 ASP 14.A OD2 no hydrogen 2.659 N/A GLY 42.A N THR 39.A OG1 no hydrogen 3.129 N/A MET 43.A N THR 39.A O no hydrogen 3.073 N/A GLU 44.A N GLN 40.A O no hydrogen 2.929 N/A GLN 45.A N LEU 41.A O no hydrogen 2.776 N/A HIS 46.A N GLY 42.A O no hydrogen 3.190 N/A HIS 46.A NE2 ARG 11.A O no hydrogen 2.804 N/A TYR 47.A N MET 43.A O no hydrogen 3.132 N/A TYR 47.A N GLU 44.A O no hydrogen 2.913 N/A GLU 48.A N GLU 44.A O no hydrogen 3.031 N/A LEU 49.A N GLN 45.A O no hydrogen 2.935 N/A GLY 50.A N HIS 46.A O no hydrogen 2.795 N/A GLU 51.A N TYR 47.A O no hydrogen 3.054 N/A TYR 52.A N GLU 48.A O no hydrogen 2.948 N/A ILE 53.A N LEU 49.A O no hydrogen 2.937 N/A ARG 54.A N GLY 50.A O no hydrogen 3.073 N/A LYS 55.A N GLU 51.A O no hydrogen 2.892 N/A ARG 56.A N TYR 52.A O no hydrogen 2.835 N/A ARG 56.A NE TYR 52.A OH no hydrogen 3.223 N/A ARG 56.A NH1 TYR 57.A OH no hydrogen 3.104 N/A ARG 56.A NH1 GLU 285.A OE2 no hydrogen 2.588 N/A TYR 57.A N ILE 53.A O no hydrogen 2.869 N/A TYR 57.A OH GLU 285.A OE1 no hydrogen 2.561 N/A ARG 58.A N LYS 55.A O no hydrogen 3.200 N/A LEU 61.A N TYR 57.A O no hydrogen 3.090 N/A SER 64.A OG PRO 93.A O no hydrogen 3.194 N/A GLN 69.A N LYS 66.A O no hydrogen 2.680 N/A TYR 71.A N LEU 251.A O no hydrogen 3.026 N/A ARG 73.A N MET 253.A O no hydrogen 2.821 N/A SER 74.A N HIS 112.A O no hydrogen 2.845 N/A SER 74.A OG THR 75.A O no hydrogen 2.971 N/A SER 74.A OG SER 255.A O no hydrogen 3.300 N/A THR 75.A N SER 255.A O no hydrogen 3.367 N/A THR 75.A OG1 THR 80.A OG1 no hydrogen 3.090 N/A THR 75.A OG1 HIS 257.A NE2 no hydrogen 2.875 N/A VAL 77.A N THR 75.A O no hydrogen 2.697 N/A ARG 79.A NE GLY 36.A O no hydrogen 3.187 N/A THR 80.A N VAL 77.A O no hydrogen 3.091 N/A THR 80.A OG1 THR 75.A O no hydrogen 3.502 N/A THR 80.A OG1 THR 75.A OG1 no hydrogen 3.090 N/A THR 80.A OG1 VAL 77.A O no hydrogen 3.088 N/A LEU 81.A N VAL 77.A O no hydrogen 2.986 N/A MET 82.A N ASP 78.A O no hydrogen 2.922 N/A SER 83.A N ARG 79.A O no hydrogen 3.075 N/A SER 83.A OG ARG 79.A O no hydrogen 2.828 N/A ALA 84.A N THR 80.A O no hydrogen 2.748 N/A MET 85.A N LEU 81.A O no hydrogen 2.808 N/A THR 86.A N MET 82.A O no hydrogen 2.691 N/A THR 86.A OG1 MET 82.A O no hydrogen 2.416 N/A ASN 87.A N SER 83.A O no hydrogen 2.869 N/A ASN 87.A ND2 HIS 46.A ND1 no hydrogen 3.180 N/A LEU 88.A N ALA 84.A O no hydrogen 3.242 N/A ALA 89.A N MET 85.A O no hydrogen 3.255 N/A ALA 90.A N ASN 87.A O no hydrogen 3.145 N/A LEU 91.A N ASN 87.A O no hydrogen 3.157 N/A PHE 92.A N LEU 88.A O no hydrogen 2.997 N/A ILE 99.A N GLY 96.A O no hydrogen 2.928 N/A TRP 100.A NE1 TRP 106.A O no hydrogen 2.548 N/A ILE 103.A N ASN 101.A OD1 no hydrogen 2.801 N/A LEU 104.A N ASN 101.A OD1 no hydrogen 3.262 N/A GLN 107.A NE2 PHE 92.A O no hydrogen 3.181 N/A HIS 112.A N ILE 72.A O no hydrogen 2.902 N/A THR 113.A OG1 SER 74.A O no hydrogen 2.985 N/A GLU 118.A N PRO 115.A O no hydrogen 2.720 N/A ASP 119.A N LEU 116.A O no hydrogen 3.191 N/A LEU 121.A N ASP 119.A OD1 no hydrogen 3.409 N/A LEU 122.A N ASP 119.A OD1 no hydrogen 2.861 N/A TYR 123.A N ASP 119.A OD1 no hydrogen 3.226 N/A LEU 124.A N LEU 122.A O no hydrogen 2.986 N/A PHE 126.A N GLN 227.A OE1 no hydrogen 2.697 N/A ARG 131.A N CYS 340.A O no hydrogen 2.614 N/A ARG 131.A NE GLU 222.A OE2 no hydrogen 2.791 N/A ARG 131.A NH1 GLU 134.A OE2 no hydrogen 3.308 N/A ARG 131.A NH2 GLU 222.A OE1 no hydrogen 3.009 N/A ARG 131.A NH2 GLU 222.A OE2 no hydrogen 3.567 N/A PHE 132.A N CYS 129.A O no hydrogen 2.659 N/A GLN 133.A N CYS 129.A O no hydrogen 2.951 N/A GLN 133.A NE2 ARG 127.A O no hydrogen 2.814 N/A GLU 134.A N PRO 130.A O no hydrogen 2.680 N/A LEU 135.A N ARG 131.A O no hydrogen 2.917 N/A GLU 136.A N PHE 132.A O no hydrogen 2.804 N/A SER 137.A N GLN 133.A O no hydrogen 3.390 N/A SER 137.A OG GLN 133.A O no hydrogen 3.554 N/A GLU 138.A N GLU 134.A O no hydrogen 3.272 N/A THR 139.A N LEU 135.A O no hydrogen 3.057 N/A THR 139.A OG1 LEU 135.A O no hydrogen 2.762 N/A THR 139.A OG1 GLU 136.A O no hydrogen 3.329 N/A LEU 140.A N GLU 136.A O no hydrogen 3.059 N/A LYS 141.A N SER 137.A O no hydrogen 2.869 N/A LYS 141.A N GLU 138.A O no hydrogen 2.916 N/A SER 142.A N THR 139.A O no hydrogen 3.101 N/A PHE 145.A N SER 142.A OG no hydrogen 2.712 N/A GLN 146.A N SER 142.A O no hydrogen 3.329 N/A LYS 147.A N GLU 143.A O no hydrogen 2.900 N/A LYS 147.A NZ GLU 144.A OE1 no hydrogen 2.908 N/A ARG 148.A N PHE 145.A O no hydrogen 2.927 N/A LEU 149.A N PHE 145.A O no hydrogen 3.004 N/A HIS 150.A N GLN 146.A O no hydrogen 2.822 N/A TYR 152.A OH GLU 205.A OE1 no hydrogen 2.962 N/A LYS 153.A N LEU 149.A O no hydrogen 3.279 N/A LYS 153.A N HIS 150.A O no hydrogen 3.062 N/A LYS 153.A NZ GLN 168.A OE1 no hydrogen 3.375 N/A ILE 156.A N TYR 152.A O no hydrogen 2.721 N/A ALA 157.A N LYS 153.A O no hydrogen 3.429 N/A THR 158.A N ASP 154.A O no hydrogen 3.246 N/A LEU 159.A N PHE 155.A O no hydrogen 2.913 N/A GLY 160.A N ILE 156.A O no hydrogen 3.249 N/A LYS 161.A N THR 158.A O no hydrogen 2.981 N/A LEU 162.A N THR 158.A O no hydrogen 3.209 N/A SER 163.A N LEU 159.A O no hydrogen 2.605 N/A SER 163.A OG LEU 165.A O no hydrogen 3.252 N/A GLY 164.A N GLY 160.A O no hydrogen 3.051 N/A LEU 165.A N SER 163.A OG no hydrogen 2.809 N/A GLY 172.A N ASP 169.A OD2 no hydrogen 3.121 N/A ILE 173.A N ASP 169.A O no hydrogen 3.170 N/A TRP 174.A N LEU 170.A O no hydrogen 2.981 N/A SER 175.A N PHE 171.A O no hydrogen 2.849 N/A SER 175.A OG PHE 171.A O no hydrogen 3.561 N/A LYS 176.A N GLY 172.A O no hydrogen 2.602 N/A VAL 177.A N ILE 173.A O no hydrogen 2.957 N/A TYR 178.A N ILE 173.A O no hydrogen 2.940 N/A ASP 179.A N TRP 174.A O no hydrogen 2.900 N/A LEU 181.A N VAL 177.A O no hydrogen 3.234 N/A TYR 182.A N TYR 178.A O no hydrogen 2.786 N/A CYS 183.A N ASP 179.A O no hydrogen 2.863 N/A CYS 183.A SG ARG 15.A O no hydrogen 3.803 N/A CYS 183.A SG ASP 179.A O no hydrogen 3.346 N/A GLU 184.A N PRO 180.A O no hydrogen 2.909 N/A SER 185.A N LEU 181.A O no hydrogen 3.022 N/A SER 185.A OG LEU 181.A O no hydrogen 3.382 N/A SER 185.A OG TYR 182.A O no hydrogen 2.558 N/A VAL 186.A N TYR 182.A O no hydrogen 2.887 N/A HIS 187.A N CYS 183.A O no hydrogen 3.139 N/A HIS 187.A N GLU 184.A O no hydrogen 2.977 N/A HIS 187.A ND1 CYS 183.A O no hydrogen 2.989 N/A ASN 188.A N SER 185.A O no hydrogen 3.191 N/A PHE 189.A N GLU 184.A O no hydrogen 3.104 N/A ALA 195.A N PRO 192.A O no hydrogen 2.722 N/A ASP 198.A N THR 196.A OG1 no hydrogen 3.044 N/A THR 199.A OG1 TRP 194.A O no hydrogen 2.910 N/A MET 200.A N THR 196.A O no hydrogen 2.875 N/A THR 201.A N GLU 197.A O no hydrogen 3.128 N/A THR 201.A OG1 GLU 197.A O no hydrogen 2.967 N/A LYS 202.A N ASP 198.A O no hydrogen 2.830 N/A LEU 203.A N THR 199.A O no hydrogen 2.801 N/A ARG 204.A N MET 200.A O no hydrogen 2.646 N/A ARG 204.A NH1 GLU 208.A OE2 no hydrogen 2.854 N/A GLU 205.A N THR 201.A O no hydrogen 2.880 N/A LEU 206.A N LYS 202.A O no hydrogen 3.163 N/A SER 207.A N LEU 203.A O no hydrogen 2.995 N/A SER 207.A OG LEU 203.A O no hydrogen 3.128 N/A GLU 208.A N ARG 204.A O no hydrogen 2.682 N/A LEU 209.A N GLU 205.A O no hydrogen 2.975 N/A SER 210.A N LEU 206.A O no hydrogen 2.892 N/A SER 210.A OG SER 207.A O no hydrogen 2.553 N/A LEU 211.A N SER 207.A O no hydrogen 3.183 N/A LEU 211.A N GLU 208.A O no hydrogen 3.054 N/A LEU 212.A N GLU 208.A O no hydrogen 3.123 N/A SER 213.A N LEU 209.A O no hydrogen 2.857 N/A SER 213.A OG LEU 209.A O no hydrogen 3.223 N/A SER 213.A OG SER 210.A O no hydrogen 3.239 N/A LEU 214.A N LEU 211.A O no hydrogen 2.977 N/A TYR 215.A N LEU 211.A O no hydrogen 3.016 N/A TYR 215.A OH THR 259.A O no hydrogen 2.786 N/A GLY 216.A N LEU 212.A O no hydrogen 2.494 N/A HIS 218.A NE2 GLU 138.A OE1 no hydrogen 2.863 N/A GLN 220.A NE2 MET 266.A O no hydrogen 3.580 N/A LYS 223.A NZ THR 139.A OG1 no hydrogen 3.097 N/A LYS 223.A NZ SER 213.A O no hydrogen 3.284 N/A LYS 223.A NZ GLY 216.A O no hydrogen 2.718 N/A SER 224.A N GLN 220.A O no hydrogen 2.633 N/A SER 224.A OG GLN 220.A O no hydrogen 3.459 N/A ARG 225.A N LYS 221.A O no hydrogen 2.822 N/A ARG 225.A N GLU 222.A O no hydrogen 2.725 N/A ARG 225.A NE GLU 339.A OE1 no hydrogen 3.239 N/A ARG 225.A NH1 PRO 330.A O no hydrogen 2.949 N/A ARG 225.A NH1 ILE 332.A O no hydrogen 3.216 N/A ARG 225.A NH2 GLU 339.A OE1 no hydrogen 3.082 N/A LEU 226.A N LYS 223.A O no hydrogen 2.622 N/A GLN 227.A N SER 224.A O no hydrogen 3.259 N/A GLN 227.A NE2 PHE 126.A O no hydrogen 2.887 N/A GLY 229.A N SER 224.A O no hydrogen 3.077 N/A VAL 232.A N GLY 228.A O no hydrogen 2.586 N/A ASN 233.A N GLY 229.A O no hydrogen 2.812 N/A GLU 234.A N VAL 230.A O no hydrogen 2.963 N/A ILE 235.A N LEU 231.A O no hydrogen 2.907 N/A LEU 236.A N VAL 232.A O no hydrogen 2.930 N/A ASN 237.A N ASN 233.A O no hydrogen 2.528 N/A HIS 238.A N GLU 234.A O no hydrogen 2.892 N/A HIS 238.A N ILE 235.A O no hydrogen 2.874 N/A MET 239.A N ILE 235.A O no hydrogen 2.963 N/A LYS 240.A N LEU 236.A O no hydrogen 3.114 N/A ARG 241.A N ASN 237.A O no hydrogen 3.469 N/A ARG 241.A NH1 ASN 237.A OD1 no hydrogen 3.416 N/A ARG 241.A NH2 ASN 237.A OD1 no hydrogen 3.464 N/A ALA 242.A N HIS 238.A O no hydrogen 2.888 N/A THR 243.A N MET 239.A O no hydrogen 3.008 N/A THR 243.A N LYS 240.A O no hydrogen 2.820 N/A GLN 244.A N LYS 240.A O no hydrogen 3.043 N/A GLN 244.A N ARG 241.A O no hydrogen 2.968 N/A ILE 245.A N ARG 241.A O no hydrogen 3.007 N/A TYR 248.A OH HIS 238.A ND1 no hydrogen 2.813 N/A LYS 249.A NZ GLU 68.A O no hydrogen 3.436 N/A LYS 250.A N GLN 69.A O no hydrogen 2.875 N/A LYS 250.A NZ PHE 60.A O no hydrogen 3.158 N/A LEU 251.A N GLN 69.A O no hydrogen 2.952 N/A ILE 252.A N VAL 6.A O no hydrogen 3.217 N/A MET 253.A N TYR 71.A O no hydrogen 2.744 N/A TYR 254.A N LEU 8.A O no hydrogen 2.801 N/A SER 255.A N ARG 73.A O no hydrogen 2.878 N/A SER 255.A OG THR 80.A O no hydrogen 2.925 N/A ALA 256.A N PHE 10.A O no hydrogen 2.978 N/A HIS 257.A N THR 260.A OG1 no hydrogen 3.399 N/A THR 259.A OG1 LEU 124.A O no hydrogen 2.785 N/A THR 259.A OG1 ASP 258.A OD1 no hydrogen 3.410 N/A THR 260.A N HIS 257.A O no hydrogen 2.848 N/A THR 260.A OG1 LEU 122.A O no hydrogen 2.647 N/A THR 260.A OG1 HIS 257.A O no hydrogen 3.124 N/A VAL 261.A N HIS 257.A O no hydrogen 3.054 N/A SER 262.A N ASP 258.A O no hydrogen 2.736 N/A SER 262.A OG ASP 258.A O no hydrogen 2.665 N/A GLY 263.A N THR 259.A O no hydrogen 2.813 N/A LEU 264.A N THR 260.A O no hydrogen 2.617 N/A GLN 265.A N VAL 261.A O no hydrogen 3.011 N/A MET 266.A N SER 262.A O no hydrogen 2.696 N/A ALA 267.A N GLY 263.A O no hydrogen 3.356 N/A LEU 268.A N LEU 264.A O no hydrogen 3.194 N/A ASP 269.A N MET 266.A O no hydrogen 3.145 N/A VAL 270.A N GLN 265.A O no hydrogen 2.848 N/A TYR 271.A OH LEU 274.A O no hydrogen 2.825 N/A LEU 274.A N ASN 272.A OD1 no hydrogen 2.927 N/A ALA 279.A N HIS 12.A O no hydrogen 3.087 N/A SER 280.A N PRO 277.A O no hydrogen 2.782 N/A SER 280.A OG PRO 277.A O no hydrogen 2.495 N/A CYS 281.A N ARG 300.A O no hydrogen 2.747 N/A HIS 282.A N VAL 9.A O no hydrogen 3.073 N/A HIS 282.A ND1 GLN 265.A OE1 no hydrogen 2.936 N/A LEU 283.A N TYR 298.A O no hydrogen 3.100 N/A THR 284.A N THR 7.A O no hydrogen 3.108 N/A GLU 285.A N GLU 296.A O no hydrogen 2.859 N/A LEU 286.A N PHE 5.A O no hydrogen 2.670 N/A TYR 287.A N PHE 294.A O no hydrogen 2.951 N/A TYR 287.A OH GLU 285.A OE2 no hydrogen 2.657 N/A PHE 288.A N GLU 2.A O no hydrogen 2.711 N/A GLU 289.A N GLU 292.A O no hydrogen 2.795 N/A GLU 292.A N GLU 289.A O no hydrogen 2.739 N/A PHE 294.A N TYR 287.A O no hydrogen 2.865 N/A VAL 295.A N CYS 319.A O no hydrogen 2.514 N/A GLU 296.A N GLU 285.A O no hydrogen 2.996 N/A TYR 298.A N LEU 283.A O no hydrogen 2.837 N/A TYR 298.A OH GLU 296.A OE1 no hydrogen 2.781 N/A TYR 299.A N TYR 308.A O no hydrogen 2.744 N/A ARG 300.A N CYS 281.A O no hydrogen 2.734 N/A ARG 300.A NH1 GLU 48.A OE2 no hydrogen 2.850 N/A ARG 300.A NH2 GLU 48.A OE2 no hydrogen 2.644 N/A THR 303.A OG1 GLN 304.A OE1 no hydrogen 3.316 N/A GLN 304.A N GLN 304.A OE1 no hydrogen 2.513 N/A TYR 308.A N TYR 299.A O no hydrogen 2.992 N/A LEU 310.A N MET 297.A O no hydrogen 2.977 N/A CYS 315.A SG SER 316.A O no hydrogen 3.834 N/A SER 318.A N SER 316.A OG no hydrogen 2.921 N/A SER 318.A OG GLU 296.A OE2 no hydrogen 3.422 N/A CYS 319.A N VAL 295.A O no hydrogen 3.253 N/A LEU 321.A N TYR 293.A O no hydrogen 2.764 N/A ARG 323.A NH1 GLY 314.A O no hydrogen 2.681 N/A PHE 324.A N PRO 320.A O no hydrogen 2.882 N/A ALA 325.A N LEU 321.A O no hydrogen 2.910 N/A GLU 326.A N GLU 322.A O no hydrogen 3.211 N/A LEU 327.A N ARG 323.A O no hydrogen 2.651 N/A VAL 328.A N PHE 324.A O no hydrogen 2.837 N/A GLY 329.A N GLU 326.A O no hydrogen 3.258 N/A VAL 331.A N VAL 328.A O no hydrogen 3.297 N/A GLN 334.A N GLU 339.A OE2 no hydrogen 2.643 N/A TRP 336.A NE1 LEU 226.A O no hydrogen 2.993 N/A THR 338.A OG1 ASP 335.A O no hydrogen 2.866 N/A THR 338.A OG1 ASP 335.A OD2 no hydrogen 2.580 N/A GLU 339.A N ASP 335.A O no hydrogen 2.902 N/A CYS 340.A N SER 337.A O no hydrogen 3.016 N/A CYS 340.A SG TRP 336.A O no hydrogen 3.303 N/A MET 341.A N THR 338.A O no hydrogen 2.932 N/A THR 342.A OG1 GLU 134.A OE2 no hydrogen 3.325 N/A THR 342.A OG1 THR 342.A O no hydrogen 2.679 N/A