Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 1ep4_B.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 3.A OG1 ASP 110.A OD1 no hydrogen 3.188 N/A LYS 9.A N ARG 79.A O no hydrogen 3.399 N/A LYS 9.A NZ THR 80.A O no hydrogen 2.587 N/A VAL 17.A N ASN 53.A O no hydrogen 2.892 N/A GLN 19.A NE2 TRP 20.A O no hydrogen 2.799 N/A GLN 19.A NE2 VAL 56.A O no hydrogen 3.045 N/A LYS 26.A N THR 23.A OG1 no hydrogen 3.221 N/A LYS 26.A NZ GLU 372.A OE1 no hydrogen 3.353 N/A ILE 27.A N THR 23.A O no hydrogen 3.057 N/A LYS 28.A N GLU 24.A O no hydrogen 2.724 N/A ALA 29.A N GLU 25.A O no hydrogen 2.997 N/A LEU 30.A N LYS 26.A O no hydrogen 3.103 N/A VAL 31.A N ILE 27.A O no hydrogen 2.950 N/A GLU 32.A N LYS 28.A O no hydrogen 3.183 N/A ILE 33.A N ALA 29.A O no hydrogen 3.205 N/A CYS 34.A N LEU 30.A O no hydrogen 3.100 N/A CYS 34.A SG LEU 30.A O no hydrogen 2.974 N/A THR 35.A N VAL 31.A O no hydrogen 3.494 N/A THR 35.A OG1 VAL 31.A O no hydrogen 3.201 N/A THR 35.A OG1 GLU 32.A O no hydrogen 3.216 N/A GLU 36.A N GLU 32.A O no hydrogen 3.441 N/A MET 37.A N ILE 33.A O no hydrogen 3.109 N/A GLU 38.A N CYS 34.A O no hydrogen 2.749 N/A LYS 39.A N THR 35.A O no hydrogen 2.445 N/A GLU 40.A N GLU 36.A O no hydrogen 2.881 N/A GLY 41.A N GLU 38.A O no hydrogen 2.610 N/A LYS 42.A NZ GLU 40.A OE1 no hydrogen 2.831 N/A ILE 43.A N MET 37.A O no hydrogen 3.432 N/A SER 44.A N GLN 134.A O no hydrogen 3.182 N/A SER 44.A OG ASN 136.A OD1 no hydrogen 3.073 N/A LYS 45.A NZ TYR 133.A OH no hydrogen 3.001 N/A ILE 46.A N ARG 132.A O no hydrogen 3.217 N/A GLU 49.A N GLU 49.A OE2 no hydrogen 2.640 N/A ASN 50.A ND2 LYS 115.A O no hydrogen 2.800 N/A TYR 52.A N ASN 50.A OD1 no hydrogen 2.812 N/A TYR 52.A OH ASP 13.A OD1 no hydrogen 2.519 N/A TYR 52.A OH ASP 13.A OD2 no hydrogen 3.236 N/A ASN 53.A N PRO 15.A O no hydrogen 2.712 N/A THR 54.A N ALA 118.A O no hydrogen 2.992 N/A VAL 56.A N GLN 19.A OE1 no hydrogen 3.065 N/A PHE 57.A N LEU 70.A O no hydrogen 2.704 N/A ILE 59.A N ARG 68.A O no hydrogen 2.927 N/A ARG 68.A N ILE 59.A O no hydrogen 2.445 N/A LYS 69.A NZ TYR 135.A OH no hydrogen 2.416 N/A LEU 70.A N PHE 57.A O no hydrogen 3.066 N/A ASP 72.A N PRO 55.A O no hydrogen 2.868 N/A ARG 74.A N ASP 72.A OD2 no hydrogen 3.382 N/A ARG 74.A NE ASP 72.A OD1 no hydrogen 3.382 N/A ARG 74.A NE ASP 72.A OD2 no hydrogen 2.865 N/A ARG 74.A NH2 ASP 72.A OD1 no hydrogen 3.113 N/A ASN 77.A N PHE 73.A O no hydrogen 2.777 N/A ASN 77.A ND2 GLY 141.A O no hydrogen 3.128 N/A LYS 78.A N ARG 74.A O no hydrogen 3.118 N/A ARG 79.A N LEU 76.A O no hydrogen 2.738 N/A ARG 79.A NE GLU 75.A O no hydrogen 3.546 N/A ARG 79.A NH1 ASP 13.A O no hydrogen 2.739 N/A ARG 79.A NH2 GLU 75.A OE2 no hydrogen 2.928 N/A THR 80.A OG1 ASN 77.A O no hydrogen 3.273 N/A GLN 81.A N LYS 7.A O no hydrogen 2.862 N/A HIS 85.A NE2 ILE 350.A O no hydrogen 2.694 N/A LYS 92.A N GLY 88.A O no hydrogen 2.822 N/A SER 94.A OG HIS 208.A ND1 no hydrogen 3.343 N/A VAL 95.A N LEU 207.A O no hydrogen 2.681 N/A THR 96.A N VAL 178.A O no hydrogen 2.813 N/A LEU 98.A N LEU 176.A O no hydrogen 2.787 N/A VAL 100.A N ASP 174.A O no hydrogen 2.976 N/A GLY 101.A N ASP 99.A OD2 no hydrogen 2.673 N/A TYR 104.A N GLY 101.A O no hydrogen 3.097 N/A TYR 104.A OH MET 173.A O no hydrogen 2.411 N/A PHE 105.A N ASP 102.A O no hydrogen 2.689 N/A SER 106.A N ALA 103.A O no hydrogen 3.119 N/A SER 106.A OG ALA 103.A O no hydrogen 3.518 N/A LEU 109.A N ASN 136.A O no hydrogen 2.809 N/A PHE 113.A N ASP 110.A O no hydrogen 2.768 N/A ARG 114.A N ASP 110.A O no hydrogen 3.317 N/A ARG 114.A N GLU 111.A O no hydrogen 3.131 N/A ARG 114.A NE LEU 109.A O no hydrogen 2.877 N/A ARG 114.A NH2 LEU 109.A O no hydrogen 3.080 N/A LYS 115.A NZ ASP 112.A O no hydrogen 2.596 N/A LYS 115.A NZ TYR 116.A OH no hydrogen 3.426 N/A TYR 116.A N PHE 113.A O no hydrogen 2.899 N/A THR 117.A N ARG 114.A O no hydrogen 2.925 N/A THR 117.A OG1 ARG 114.A O no hydrogen 2.562 N/A PHE 119.A N TYR 133.A O no hydrogen 3.118 N/A ILE 121.A N ILE 131.A O no hydrogen 2.757 N/A SER 123.A OG THR 128.A O no hydrogen 2.672 N/A ASN 125.A ND2 GLU 127.A OE1 no hydrogen 3.039 N/A ASN 126.A N SER 123.A O no hydrogen 3.181 N/A THR 128.A N SER 123.A OG no hydrogen 3.415 N/A ILE 131.A N ILE 121.A O no hydrogen 2.874 N/A ARG 132.A NH1 TYR 52.A O no hydrogen 3.006 N/A ARG 132.A NH1 THR 120.A OG1 no hydrogen 2.993 N/A ARG 132.A NH2 ASN 50.A O no hydrogen 2.853 N/A ARG 132.A NH2 TYR 52.A O no hydrogen 2.862 N/A TYR 133.A N PHE 119.A O no hydrogen 3.094 N/A TYR 135.A N THR 117.A OG1 no hydrogen 2.968 N/A ASN 136.A N LYS 42.A O no hydrogen 2.625 N/A GLY 141.A N ASP 174.A OD2 no hydrogen 3.393 N/A LYS 143.A N ASN 77.A OD1 no hydrogen 2.618 N/A SER 145.A N TRP 142.A O no hydrogen 2.819 N/A SER 145.A OG PRO 139.A O no hydrogen 2.624 N/A ILE 148.A N GLY 144.A O no hydrogen 3.157 N/A PHE 149.A N SER 145.A O no hydrogen 3.214 N/A SER 152.A N PHE 149.A O no hydrogen 2.858 N/A MET 153.A N GLN 150.A O no hydrogen 2.825 N/A THR 154.A N GLN 150.A O no hydrogen 3.160 N/A THR 154.A OG1 GLN 150.A O no hydrogen 3.330 N/A ILE 156.A N MET 153.A O no hydrogen 3.101 N/A LEU 157.A N THR 154.A O no hydrogen 2.661 N/A GLU 158.A N THR 154.A O no hydrogen 3.244 N/A PHE 160.A N GLU 158.A O no hydrogen 2.402 N/A ARG 161.A N GLU 158.A O no hydrogen 2.680 N/A LYS 162.A N GLU 158.A O no hydrogen 2.769 N/A VAL 168.A N GLY 179.A O no hydrogen 2.721 N/A TYR 170.A N TYR 177.A O no hydrogen 2.621 N/A TYR 172.A N ASP 175.A O no hydrogen 2.876 N/A ASP 175.A N TYR 172.A O no hydrogen 2.525 N/A LEU 176.A N LEU 98.A O no hydrogen 2.889 N/A TYR 177.A N TYR 170.A O no hydrogen 2.551 N/A TYR 177.A OH ASP 175.A OD1 no hydrogen 2.876 N/A VAL 178.A N THR 96.A O no hydrogen 2.545 N/A GLY 179.A N VAL 168.A O no hydrogen 2.439 N/A SER 180.A N SER 94.A O no hydrogen 3.314 N/A HIS 187.A N ILE 184.A O no hydrogen 3.136 N/A THR 189.A OG1 GLY 185.A O no hydrogen 3.494 N/A LYS 190.A N HIS 187.A O no hydrogen 2.627 N/A ILE 191.A N HIS 187.A O no hydrogen 3.424 N/A ILE 191.A N ARG 188.A O no hydrogen 3.290 N/A GLU 192.A N ARG 188.A O no hydrogen 2.717 N/A LEU 194.A N ILE 191.A O no hydrogen 2.531 N/A ARG 195.A N ILE 191.A O no hydrogen 2.710 N/A GLN 196.A N GLU 193.A O no hydrogen 3.262 N/A HIS 197.A N LEU 194.A O no hydrogen 2.854 N/A LEU 198.A N LEU 194.A O no hydrogen 3.313 N/A TRP 201.A N LEU 198.A O no hydrogen 2.694 N/A GLY 202.A N LEU 199.A O no hydrogen 3.083 N/A LEU 207.A N VAL 95.A O no hydrogen 2.859 N/A HIS 208.A ND1 LYS 93.A O no hydrogen 3.028 N/A ASP 210.A N LYS 92.A O no hydrogen 3.342 N/A LYS 211.A N HIS 208.A O no hydrogen 3.089 N/A THR 226.A N ASP 229.A OD1 no hydrogen 3.294 N/A VAL 227.A N GLU 264.A O no hydrogen 2.932 N/A ASN 228.A N LEU 262.A O no hydrogen 2.967 N/A ASP 229.A N THR 226.A OG1 no hydrogen 3.175 N/A ILE 230.A N THR 226.A O no hydrogen 2.895 N/A GLN 231.A N VAL 227.A O no hydrogen 2.913 N/A LYS 232.A N ASN 228.A O no hydrogen 2.862 N/A LEU 233.A N ASP 229.A O no hydrogen 2.965 N/A VAL 234.A N ILE 230.A O no hydrogen 2.818 N/A GLY 235.A N GLN 231.A O no hydrogen 3.131 N/A LYS 236.A N LYS 232.A O no hydrogen 2.843 N/A LYS 236.A NZ VAL 218.A O no hydrogen 2.683 N/A LEU 237.A N LEU 233.A O no hydrogen 2.785 N/A ASN 238.A N VAL 234.A O no hydrogen 2.759 N/A TRP 239.A N GLY 235.A O no hydrogen 3.097 N/A ALA 240.A N LYS 236.A O no hydrogen 3.151 N/A SER 241.A N ASN 238.A O no hydrogen 2.854 N/A SER 241.A OG ASN 238.A O no hydrogen 2.689 N/A GLN 242.A N TRP 239.A O no hydrogen 2.855 N/A TYR 244.A N ALA 240.A O no hydrogen 3.003 N/A TYR 244.A OH GLU 285.A O no hydrogen 2.726 N/A ILE 247.A N TYR 244.A O no hydrogen 3.428 N/A LYS 248.A N ASN 279.A OD1 no hydrogen 3.010 N/A GLN 251.A N GLU 275.A OE1 no hydrogen 3.474 N/A LEU 252.A N GLU 275.A OE2 no hydrogen 3.290 N/A CYS 253.A N VAL 249.A O no hydrogen 3.005 N/A LYS 254.A N ARG 250.A O no hydrogen 3.069 N/A LYS 254.A N GLN 251.A O no hydrogen 3.196 N/A LEU 255.A N LEU 252.A O no hydrogen 2.651 N/A LEU 256.A N LEU 252.A O no hydrogen 3.398 N/A ARG 257.A N LYS 254.A O no hydrogen 3.155 N/A THR 259.A OG1 THR 259.A O no hydrogen 2.499 N/A GLU 264.A N ALA 261.A O no hydrogen 3.144 N/A ILE 266.A N TRP 225.A O no hydrogen 2.744 N/A ALA 272.A N THR 269.A OG1 no hydrogen 3.077 N/A GLU 273.A N THR 269.A O no hydrogen 2.829 N/A LEU 274.A N GLU 270.A O no hydrogen 3.087 N/A GLU 275.A N GLU 271.A O no hydrogen 3.274 N/A LEU 276.A N ALA 272.A O no hydrogen 3.177 N/A ALA 277.A N GLU 273.A O no hydrogen 3.165 N/A GLU 278.A N LEU 274.A O no hydrogen 2.802 N/A ASN 279.A N GLU 275.A O no hydrogen 2.691 N/A ASN 279.A ND2 LYS 248.A O no hydrogen 2.742 N/A ARG 280.A N LEU 276.A O no hydrogen 2.712 N/A ARG 280.A NH1 LEU 219.A O no hydrogen 3.341 N/A ARG 280.A NH1 PRO 220.A O no hydrogen 3.273 N/A ARG 280.A NH2 PRO 220.A O no hydrogen 2.845 N/A GLU 281.A N ALA 277.A O no hydrogen 3.023 N/A ILE 282.A N GLU 278.A O no hydrogen 3.027 N/A LEU 283.A N ASN 279.A O no hydrogen 3.308 N/A LYS 284.A N GLU 281.A O no hydrogen 3.322 N/A ASP 293.A N GLN 316.A OE1 no hydrogen 2.859 N/A SER 295.A N ASP 293.A OD1 no hydrogen 3.117 N/A SER 295.A OG ASP 293.A OD1 no hydrogen 3.050 N/A SER 295.A OG ASP 293.A OD2 no hydrogen 2.874 N/A LYS 296.A N ASP 293.A O no hydrogen 2.585 N/A ILE 299.A N TYR 315.A O no hydrogen 2.747 N/A ALA 300.A N LYS 356.A O no hydrogen 3.211 N/A GLU 301.A N GLN 313.A O no hydrogen 2.935 N/A GLN 303.A N THR 311.A O no hydrogen 2.765 N/A GLN 303.A NE2 GLN 313.A OE1 no hydrogen 2.824 N/A LYS 304.A NZ ASP 332.A OD1 no hydrogen 2.754 N/A GLN 305.A N GLN 309.A O no hydrogen 2.603 N/A GLN 309.A N GLY 306.A O no hydrogen 2.990 N/A TRP 310.A N TYR 327.A O no hydrogen 3.000 N/A TRP 310.A NE1 GLN 335.A OE1 no hydrogen 3.059 N/A THR 311.A N GLN 303.A O no hydrogen 2.959 N/A THR 311.A OG1 GLN 303.A O no hydrogen 3.565 N/A THR 311.A OG1 GLN 303.A OE1 no hydrogen 3.038 N/A THR 311.A OG1 GLN 305.A OE1 no hydrogen 3.474 N/A TYR 312.A N GLY 325.A O no hydrogen 3.188 N/A TYR 312.A OH GLU 346.A OE1 no hydrogen 3.280 N/A GLN 313.A N GLU 301.A O no hydrogen 2.963 N/A GLN 313.A NE2 GLN 303.A OE1 no hydrogen 2.694 N/A ILE 314.A N LYS 323.A O no hydrogen 2.839 N/A TYR 315.A N ILE 299.A O no hydrogen 2.762 N/A TYR 315.A OH GLU 301.A OE1 no hydrogen 2.287 N/A GLN 316.A NE2 ASP 293.A O no hydrogen 3.391 N/A LYS 320.A NZ GLY 289.A O no hydrogen 3.226 N/A ASN 321.A ND2 TYR 395.A OH no hydrogen 2.700 N/A LEU 322.A N ILE 314.A O no hydrogen 2.689 N/A LYS 323.A N ILE 314.A O no hydrogen 3.433 N/A LYS 323.A NZ THR 324.A O no hydrogen 3.082 N/A THR 324.A OG1 GLN 215.A OE1 no hydrogen 2.911 N/A GLY 325.A N TYR 312.A O no hydrogen 3.306 N/A TYR 327.A N TRP 310.A O no hydrogen 2.809 N/A TYR 327.A OH GLU 338.A OE1 no hydrogen 2.276 N/A ARG 329.A N GLY 308.A O no hydrogen 2.724 N/A GLN 335.A N ASN 331.A O no hydrogen 3.089 N/A LEU 336.A N ASP 332.A O no hydrogen 2.632 N/A THR 337.A N VAL 333.A O no hydrogen 2.838 N/A THR 337.A OG1 VAL 333.A O no hydrogen 2.947 N/A THR 337.A OG1 LYS 334.A O no hydrogen 2.633 N/A GLU 338.A N LYS 334.A O no hydrogen 2.921 N/A ALA 339.A N GLN 335.A O no hydrogen 2.933 N/A VAL 340.A N LEU 336.A O no hydrogen 3.159 N/A GLN 341.A N THR 337.A O no hydrogen 3.356 N/A GLN 341.A NE2 THR 337.A O no hydrogen 3.361 N/A GLN 341.A NE2 TYR 373.A O no hydrogen 2.878 N/A LYS 342.A N GLU 338.A O no hydrogen 2.919 N/A ILE 343.A N ALA 339.A O no hydrogen 2.878 N/A THR 344.A N VAL 340.A O no hydrogen 2.852 N/A THR 344.A OG1 VAL 340.A O no hydrogen 2.416 N/A THR 345.A N GLN 341.A O no hydrogen 2.845 N/A THR 345.A OG1 GLN 341.A O no hydrogen 2.832 N/A GLU 346.A N LYS 342.A O no hydrogen 3.131 N/A SER 347.A N ILE 343.A O no hydrogen 3.055 N/A SER 347.A OG LYS 353.A O no hydrogen 2.468 N/A ILE 348.A N THR 344.A O no hydrogen 2.874 N/A VAL 349.A N THR 345.A O no hydrogen 2.927 N/A ILE 350.A N GLU 346.A O no hydrogen 2.716 N/A TRP 351.A N SER 347.A O no hydrogen 2.864 N/A LYS 353.A NZ TYR 292.A OH no hydrogen 3.267 N/A LYS 356.A N LEU 298.A O no hydrogen 2.971 N/A PHE 357.A N GLU 381.A O no hydrogen 2.946 N/A LYS 358.A N ALA 300.A O no hydrogen 3.128 N/A LYS 358.A NZ GLU 383.A OE2 no hydrogen 2.516 N/A LEU 359.A N GLU 383.A O no hydrogen 2.806 N/A ILE 361.A N LEU 359.A O no hydrogen 2.770 N/A GLN 362.A NE2 GLU 364.A OE1 no hydrogen 3.116 N/A TRP 366.A N GLN 362.A O no hydrogen 3.207 N/A GLU 367.A N LYS 363.A O no hydrogen 3.010 N/A THR 368.A N GLU 364.A O no hydrogen 3.295 N/A THR 368.A OG1 GLU 364.A O no hydrogen 2.854 N/A TRP 369.A N THR 365.A O no hydrogen 3.133 N/A TRP 370.A N TRP 366.A O no hydrogen 2.776 N/A GLU 372.A N TRP 369.A O no hydrogen 2.891 N/A TRP 374.A NE1 TRP 378.A O no hydrogen 3.000 N/A GLN 375.A N GLN 341.A OE1 no hydrogen 3.254 N/A THR 377.A OG1 ASP 174.A OD1 no hydrogen 3.245 N/A TRP 378.A NE1 ASP 175.A OD1 no hydrogen 2.979 N/A GLU 383.A N PHE 357.A O no hydrogen 2.880 N/A VAL 385.A N LEU 359.A O no hydrogen 3.093 N/A TYR 395.A N VAL 391.A O no hydrogen 3.151 N/A