Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 1ez4_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 1.A N HIS 5.A O no hydrogen 3.375 N/A HIS 5.A NE2 GLU 32.A OE1 no hydrogen 2.763 N/A GLN 6.A N GLU 31.A OE1 no hydrogen 2.807 N/A GLN 6.A NE2 LEU 236.A O no hydrogen 2.949 N/A LYS 7.A N ASP 74.A OD2 no hydrogen 2.910 N/A LYS 7.A NZ ASP 69.A O no hydrogen 2.974 N/A LYS 7.A NZ ASP 72.A OD1 no hydrogen 2.668 N/A VAL 8.A N GLU 32.A O no hydrogen 2.895 N/A VAL 9.A N LEU 75.A O no hydrogen 2.826 N/A LEU 10.A N VAL 34.A O no hydrogen 2.743 N/A VAL 11.A N VAL 77.A O no hydrogen 2.804 N/A GLY 12.A N VAL 36.A O no hydrogen 2.789 N/A ASP 13.A N ASP 37.A OD2 no hydrogen 2.794 N/A SER 18.A N GLY 14.A O no hydrogen 2.892 N/A SER 18.A OG ASP 46.A OD1 no hydrogen 3.430 N/A SER 18.A OG ASP 46.A OD2 no hydrogen 2.735 N/A SER 19.A N ALA 15.A O no hydrogen 2.963 N/A SER 19.A OG ALA 15.A O no hydrogen 2.994 N/A SER 19.A OG VAL 16.A O no hydrogen 3.119 N/A SER 19.A OG PHE 221.A O no hydrogen 3.277 N/A TYR 20.A N VAL 16.A O no hydrogen 2.951 N/A TYR 20.A OH SER 232.A OG no hydrogen 2.788 N/A ALA 21.A N GLY 17.A O no hydrogen 2.971 N/A PHE 22.A N SER 18.A O no hydrogen 2.980 N/A ALA 23.A N SER 19.A O no hydrogen 2.862 N/A MET 24.A N TYR 20.A O no hydrogen 2.892 N/A ALA 25.A N ALA 21.A O no hydrogen 2.916 N/A GLN 26.A N PHE 22.A O no hydrogen 2.884 N/A GLN 27.A N ALA 23.A O no hydrogen 2.997 N/A GLY 28.A N ALA 25.A O no hydrogen 3.402 N/A ILE 29.A N MET 24.A O no hydrogen 3.212 N/A GLU 31.A N GLN 6.A O no hydrogen 2.932 N/A GLU 32.A N GLN 6.A O no hydrogen 2.991 N/A PHE 33.A N LYS 61.A O no hydrogen 2.827 N/A VAL 34.A N VAL 8.A O no hydrogen 2.868 N/A ILE 35.A N TYR 63.A O no hydrogen 2.808 N/A VAL 36.A N LEU 10.A O no hydrogen 2.795 N/A LYS 40.A NZ ASP 37.A O no hydrogen 2.738 N/A LYS 40.A NZ GLU 66.A OE1 no hydrogen 2.742 N/A ARG 42.A N VAL 39.A O no hydrogen 3.182 N/A THR 43.A OG1 LYS 40.A O no hydrogen 2.867 N/A THR 43.A OG1 SER 64.A OG no hydrogen 2.841 N/A LYS 44.A N LYS 40.A O no hydrogen 2.908 N/A GLY 45.A N ASP 41.A O no hydrogen 2.933 N/A ASP 46.A N ARG 42.A O no hydrogen 2.870 N/A ALA 47.A N THR 43.A O no hydrogen 2.910 N/A LEU 48.A N LYS 44.A O no hydrogen 3.352 N/A ASP 49.A N GLY 45.A O no hydrogen 3.170 N/A LEU 50.A N ASP 46.A O no hydrogen 2.774 N/A GLU 51.A N ALA 47.A O no hydrogen 2.903 N/A ASP 52.A N ASP 49.A O no hydrogen 3.323 N/A ALA 53.A N LEU 50.A O no hydrogen 2.837 N/A GLN 54.A N GLU 51.A O no hydrogen 3.235 N/A GLN 54.A NE2 GLU 51.A O no hydrogen 3.036 N/A PHE 56.A N ALA 53.A O no hydrogen 3.291 N/A THR 57.A N GLN 54.A O no hydrogen 3.249 N/A THR 57.A OG1 ALA 25.A O no hydrogen 3.329 N/A THR 57.A OG1 ALA 53.A O no hydrogen 2.935 N/A ALA 58.A N THR 57.A OG1 no hydrogen 2.698 N/A LYS 60.A N GLN 54.A OE1 no hydrogen 2.916 N/A LYS 60.A NZ MET 24.A O no hydrogen 3.142 N/A LYS 60.A NZ ILE 29.A O no hydrogen 2.739 N/A LYS 60.A NZ ALA 30.A O no hydrogen 2.905 N/A LYS 61.A N GLU 31.A O no hydrogen 2.858 N/A TYR 63.A N PHE 33.A O no hydrogen 3.146 N/A TYR 63.A OH GLU 32.A OE2 no hydrogen 2.711 N/A SER 64.A OG THR 43.A OG1 no hydrogen 2.841 N/A GLY 65.A N ILE 35.A O no hydrogen 2.786 N/A GLU 66.A N ASP 69.A OD2 no hydrogen 2.922 N/A ASP 69.A N GLU 66.A O no hydrogen 2.929 N/A CYS 70.A N TYR 67.A O no hydrogen 2.907 N/A LYS 71.A N SER 68.A O no hydrogen 3.170 N/A ALA 73.A N CYS 70.A O no hydrogen 3.000 N/A ASP 74.A N LYS 7.A O no hydrogen 2.791 N/A LEU 75.A N LYS 7.A O no hydrogen 3.383 N/A VAL 76.A N ILE 106.A O no hydrogen 2.897 N/A VAL 77.A N VAL 9.A O no hydrogen 2.850 N/A ILE 78.A N LEU 108.A O no hydrogen 2.910 N/A THR 79.A N VAL 11.A O no hydrogen 2.821 N/A THR 79.A OG1 VAL 11.A O no hydrogen 3.519 N/A ALA 80.A N VAL 11.A O no hydrogen 3.096 N/A ALA 82.A N ASN 87.A OD1 no hydrogen 2.887 N/A ASN 87.A N LEU 83.A O no hydrogen 2.755 N/A ASN 87.A ND2 ALA 82.A O no hydrogen 3.008 N/A ASN 87.A ND2 ASN 112.A O no hydrogen 2.712 N/A LEU 88.A N VAL 84.A O no hydrogen 2.752 N/A ASN 89.A N ASN 85.A O no hydrogen 3.004 N/A ASN 89.A ND2 ASN 85.A O no hydrogen 2.772 N/A ILE 90.A N LYS 86.A O no hydrogen 2.917 N/A LEU 91.A N ASN 87.A O no hydrogen 2.795 N/A SER 92.A N LEU 88.A O no hydrogen 2.882 N/A SER 92.A OG LEU 88.A O no hydrogen 3.568 N/A SER 92.A OG ASN 89.A O no hydrogen 2.940 N/A SER 93.A N ASN 89.A O no hydrogen 3.237 N/A SER 93.A N ILE 90.A O no hydrogen 2.906 N/A SER 93.A OG ILE 90.A O no hydrogen 2.616 N/A ILE 94.A N ILE 90.A O no hydrogen 3.167 N/A ILE 94.A N LEU 91.A O no hydrogen 2.893 N/A VAL 95.A N LEU 91.A O no hydrogen 2.975 N/A LYS 96.A NZ ASP 100.A OD2 no hydrogen 3.202 N/A VAL 98.A N ILE 94.A O no hydrogen 3.145 N/A VAL 99.A N VAL 95.A O no hydrogen 2.867 N/A ASP 100.A N LYS 96.A O no hydrogen 2.877 N/A SER 101.A N PRO 97.A O no hydrogen 2.989 N/A SER 101.A N VAL 98.A O no hydrogen 3.240 N/A SER 101.A OG VAL 98.A O no hydrogen 2.596 N/A GLY 102.A N VAL 99.A O no hydrogen 2.939 N/A PHE 103.A N SER 101.A OG no hydrogen 3.089 N/A ILE 106.A N ASP 74.A O no hydrogen 2.951 N/A PHE 107.A N ARG 131.A O no hydrogen 2.855 N/A LEU 108.A N VAL 76.A O no hydrogen 2.855 N/A VAL 109.A N ILE 133.A O no hydrogen 2.830 N/A ALA 110.A N ILE 78.A O no hydrogen 2.875 N/A ALA 111.A N ILE 78.A O no hydrogen 3.131 N/A LEU 117.A N PRO 113.A O no hydrogen 2.952 N/A THR 118.A N VAL 114.A O no hydrogen 2.750 N/A THR 118.A OG1 VAL 114.A O no hydrogen 2.678 N/A TYR 119.A N ASP 115.A O no hydrogen 3.027 N/A TYR 119.A OH ASP 257.A OD1 no hydrogen 2.782 N/A ALA 120.A N ILE 116.A O no hydrogen 2.924 N/A THR 121.A N LEU 117.A O no hydrogen 2.847 N/A THR 121.A OG1 LEU 117.A O no hydrogen 2.761 N/A TRP 122.A N THR 118.A O no hydrogen 3.012 N/A LYS 123.A N TYR 119.A O no hydrogen 2.898 N/A PHE 124.A N ALA 120.A O no hydrogen 2.741 N/A SER 125.A N THR 121.A O no hydrogen 2.889 N/A SER 125.A OG THR 121.A O no hydrogen 2.802 N/A SER 125.A OG TRP 122.A O no hydrogen 3.271 N/A GLY 126.A N TRP 122.A O no hydrogen 3.014 N/A PHE 127.A N SER 125.A OG no hydrogen 3.029 N/A LYS 129.A NZ ASP 250.A OD2 no hydrogen 3.032 N/A GLU 130.A N GLU 130.A OE1 no hydrogen 2.944 N/A ARG 131.A N PRO 128.A O no hydrogen 2.913 N/A ARG 131.A NH2 GLY 105.A O no hydrogen 2.653 N/A VAL 132.A N LYS 129.A O no hydrogen 3.325 N/A ILE 133.A N PHE 107.A O no hydrogen 2.862 N/A GLY 134.A N GLY 246.A O no hydrogen 3.163 N/A SER 135.A N VAL 109.A O no hydrogen 2.876 N/A THR 137.A OG1 ILE 163.A O no hydrogen 2.724 N/A SER 138.A N SER 135.A O no hydrogen 2.941 N/A SER 138.A OG SER 135.A O no hydrogen 2.662 N/A SER 141.A N THR 137.A O no hydrogen 2.797 N/A SER 141.A OG THR 137.A O no hydrogen 2.670 N/A SER 142.A N SER 138.A O no hydrogen 2.978 N/A SER 142.A OG SER 138.A O no hydrogen 2.825 N/A ARG 143.A N LEU 139.A O no hydrogen 2.985 N/A ARG 143.A NE ASP 140.A OD1 no hydrogen 3.368 N/A ARG 143.A NH2 THR 220.A OG1 no hydrogen 3.353 N/A LEU 144.A N ASP 140.A O no hydrogen 2.801 N/A ARG 145.A N SER 141.A O no hydrogen 2.849 N/A ARG 145.A NH2 ALA 161.A O no hydrogen 2.864 N/A VAL 146.A N SER 142.A O no hydrogen 2.768 N/A ALA 147.A N ARG 143.A O no hydrogen 2.946 N/A LEU 148.A N LEU 144.A O no hydrogen 2.770 N/A GLY 149.A N ARG 145.A O no hydrogen 2.775 N/A LYS 150.A N VAL 146.A O no hydrogen 2.868 N/A GLN 151.A N ALA 147.A O no hydrogen 2.918 N/A GLN 151.A NE2 GLN 151.A O no hydrogen 3.267 N/A PHE 152.A N LEU 148.A O no hydrogen 2.809 N/A VAL 154.A N GLY 149.A O no hydrogen 3.008 N/A ARG 157.A N ASP 155.A OD1 no hydrogen 3.006 N/A ARG 157.A NH2 ASP 155.A OD2 no hydrogen 2.622 N/A SER 158.A N ASP 155.A O no hydrogen 2.827 N/A VAL 159.A N PRO 156.A O no hydrogen 3.176 N/A ASP 160.A N THR 179.A O no hydrogen 2.785 N/A ILE 163.A N SER 141.A OG no hydrogen 2.963 N/A MET 164.A N PHE 172.A O no hydrogen 2.823 N/A GLU 166.A N SER 290.A OG no hydrogen 2.778 N/A GLY 168.A N GLU 166.A O no hydrogen 2.601 N/A SER 170.A N GLY 168.A O no hydrogen 2.667 N/A SER 170.A OG GLU 166.A O no hydrogen 3.556 N/A SER 170.A OG GLY 168.A O no hydrogen 3.370 N/A SER 170.A OG SER 290.A OG no hydrogen 3.267 N/A PHE 172.A N MET 164.A O no hydrogen 2.919 N/A ALA 173.A N GLU 203.A OE2 no hydrogen 2.879 N/A ALA 174.A N TYR 162.A O no hydrogen 2.883 N/A TYR 175.A N ALA 173.A O no hydrogen 2.777 N/A TYR 175.A OH LEU 199.A O no hydrogen 2.674 N/A SER 176.A N GLU 283.A OE2 no hydrogen 3.009 N/A SER 176.A OG GLU 283.A OE1 no hydrogen 2.538 N/A THR 177.A N ALA 174.A O no hydrogen 3.121 N/A THR 177.A OG1 ALA 174.A O no hydrogen 3.321 N/A THR 177.A OG1 SER 277.A OG no hydrogen 2.792 N/A ALA 178.A N TYR 175.A O no hydrogen 3.239 N/A THR 179.A N ASP 160.A O no hydrogen 2.900 N/A ILE 180.A N ARG 183.A O no hydrogen 2.905 N/A THR 182.A OG1 GLY 181.A O no hydrogen 2.555 N/A ARG 183.A N ILE 180.A O no hydrogen 3.094 N/A ARG 183.A NH2 GLU 191.A OE1 no hydrogen 3.213 N/A VAL 185.A N ALA 178.A O no hydrogen 2.896 N/A VAL 188.A N PRO 184.A O no hydrogen 3.015 N/A ALA 189.A N VAL 185.A O no hydrogen 2.835 N/A LYS 190.A N ARG 186.A O no hydrogen 2.847 N/A LYS 190.A NZ ARG 186.A O no hydrogen 3.230 N/A LYS 190.A NZ ASP 196.A OD1 no hydrogen 2.817 N/A GLU 191.A N ASP 187.A O no hydrogen 2.898 N/A GLN 192.A N ALA 189.A O no hydrogen 2.901 N/A GLY 193.A N LYS 190.A O no hydrogen 2.904 N/A VAL 194.A N ALA 189.A O no hydrogen 2.926 N/A SER 195.A N ASP 198.A OD2 no hydrogen 3.006 N/A ASP 198.A N SER 195.A OG no hydrogen 3.038 N/A LEU 199.A N SER 195.A O no hydrogen 2.966 N/A ALA 200.A N ASP 196.A O no hydrogen 2.852 N/A LYS 201.A N ASP 197.A O no hydrogen 2.868 N/A LEU 202.A N ASP 198.A O no hydrogen 2.901 N/A GLU 203.A N LEU 199.A O no hydrogen 2.934 N/A ASP 204.A N ALA 200.A O no hydrogen 2.892 N/A GLY 205.A N LYS 201.A O no hydrogen 2.866 N/A VAL 206.A N LEU 202.A O no hydrogen 3.105 N/A ARG 207.A N GLU 203.A O no hydrogen 2.988 N/A ARG 207.A NH1 ASP 204.A OD1 no hydrogen 2.704 N/A ARG 207.A NH2 GLU 171.A O no hydrogen 2.627 N/A ASN 208.A N ASP 204.A O no hydrogen 2.865 N/A LYS 209.A N VAL 206.A O no hydrogen 3.202 N/A ASP 212.A N ASN 208.A O no hydrogen 2.902 N/A ILE 213.A N LYS 209.A O no hydrogen 2.924 N/A ILE 214.A N ALA 210.A O no hydrogen 2.880 N/A ASN 215.A N TYR 211.A O no hydrogen 2.900 N/A LEU 216.A N ASP 212.A O no hydrogen 3.037 N/A LEU 216.A N ILE 213.A O no hydrogen 2.999 N/A LYS 217.A N ILE 213.A O no hydrogen 2.862 N/A GLY 218.A N ILE 214.A O no hydrogen 2.756 N/A GLY 225.A N PHE 221.A O no hydrogen 3.020 N/A THR 226.A N TYR 222.A O no hydrogen 3.029 N/A THR 226.A OG1 TYR 222.A O no hydrogen 2.964 N/A ALA 227.A N GLY 223.A O no hydrogen 2.975 N/A LEU 228.A N ILE 224.A O no hydrogen 2.913 N/A MET 229.A N GLY 225.A O no hydrogen 3.069 N/A ARG 230.A N THR 226.A O no hydrogen 2.912 N/A ARG 230.A NH1 ARG 230.A O no hydrogen 3.119 N/A ARG 230.A NH1 GLU 239.A OE1 no hydrogen 2.626 N/A ILE 231.A N ALA 227.A O no hydrogen 2.970 N/A SER 232.A N LEU 228.A O no hydrogen 3.022 N/A SER 232.A OG TYR 20.A OH no hydrogen 2.788 N/A SER 232.A OG LEU 228.A O no hydrogen 2.665 N/A LYS 233.A N MET 229.A O no hydrogen 2.794 N/A ALA 234.A N ARG 230.A O no hydrogen 3.042 N/A ILE 235.A N ILE 231.A O no hydrogen 3.101 N/A LEU 236.A N SER 232.A O no hydrogen 2.849 N/A ARG 237.A N LYS 233.A O no hydrogen 2.853 N/A ARG 237.A NH1 GLY 28.A O no hydrogen 3.330 N/A ASP 238.A N ILE 235.A O no hydrogen 3.257 N/A GLU 239.A N ALA 234.A O no hydrogen 2.951 N/A ALA 241.A N ILE 266.A O no hydrogen 3.146 N/A LEU 243.A N ALA 264.A O no hydrogen 2.906 N/A VAL 245.A N THR 262.A O no hydrogen 3.076 N/A GLY 246.A N GLY 134.A O no hydrogen 2.750 N/A ALA 247.A N ILE 260.A O no hydrogen 2.992 N/A TYR 248.A OH ASP 257.A OD1 no hydrogen 2.729 N/A MET 249.A N ILE 258.A O no hydrogen 2.915 N/A ASP 250.A N GLN 252.A OE1 no hydrogen 2.746 N/A GLY 251.A N LEU 255.A O no hydrogen 2.775 N/A GLN 252.A N GLN 252.A OE1 no hydrogen 2.638 N/A TYR 253.A N GLU 276.A OE1 no hydrogen 3.265 N/A TYR 253.A N GLU 276.A OE2 no hydrogen 3.172 N/A TYR 253.A OH ILE 275.A O no hydrogen 3.418 N/A GLY 254.A N GLY 251.A O no hydrogen 2.963 N/A LEU 255.A N GLN 252.A O no hydrogen 2.922 N/A ASP 257.A N MET 249.A O no hydrogen 2.849 N/A TYR 259.A OH LYS 129.A O no hydrogen 3.050 N/A TYR 259.A OH VAL 132.A O no hydrogen 3.143 N/A ILE 260.A N ALA 247.A O no hydrogen 3.028 N/A THR 262.A N VAL 245.A O no hydrogen 2.878 N/A ALA 264.A N LEU 243.A O no hydrogen 3.055 N/A ILE 265.A N GLN 273.A O no hydrogen 2.843 N/A ILE 266.A N ALA 241.A O no hydrogen 2.861 N/A GLY 267.A N GLY 270.A O no hydrogen 2.891 N/A GLY 268.A N ASP 238.A OD1 no hydrogen 2.862 N/A GLY 270.A N GLY 267.A O no hydrogen 2.905 N/A LEU 271.A N GLU 130.A O no hydrogen 2.894 N/A LYS 272.A N ILE 265.A O no hydrogen 2.734 N/A LYS 272.A NZ ASN 240.A OD1 no hydrogen 3.197 N/A ILE 275.A N PRO 263.A O no hydrogen 2.879 N/A SER 277.A N TYR 253.A OH no hydrogen 2.838 N/A LEU 279.A N SER 277.A O no hydrogen 2.694 N/A SER 280.A N SER 176.A OG no hydrogen 2.999 N/A GLU 283.A N SER 280.A OG no hydrogen 3.047 N/A LEU 284.A N SER 280.A O no hydrogen 2.840 N/A LYS 285.A N ALA 281.A O no hydrogen 2.999 N/A LYS 285.A NZ ASP 289.A OD1 no hydrogen 3.099 N/A LYS 285.A NZ ASP 289.A OD2 no hydrogen 3.169 N/A LYS 286.A N ASP 282.A O no hydrogen 3.037 N/A MET 287.A N GLU 283.A O no hydrogen 2.962 N/A GLN 288.A N LEU 284.A O no hydrogen 2.856 N/A GLN 288.A NE2 TYR 253.A O no hydrogen 2.743 N/A ASP 289.A N LYS 285.A O no hydrogen 2.830 N/A SER 290.A N LYS 286.A O no hydrogen 2.920 N/A SER 290.A OG SER 170.A OG no hydrogen 3.267 N/A ALA 291.A N MET 287.A O no hydrogen 2.881 N/A ALA 292.A N GLN 288.A O no hydrogen 2.850 N/A THR 293.A N ASP 289.A O no hydrogen 3.351 N/A LYS 295.A N ALA 291.A O no hydrogen 3.315 N/A LYS 295.A NZ ASN 256.A O no hydrogen 3.083 N/A LYS 296.A NZ ASP 300.A OD2 no hydrogen 2.975 N/A VAL 297.A N THR 293.A O no hydrogen 2.969 N/A LEU 298.A N LEU 294.A O no hydrogen 2.848 N/A ASN 299.A N LYS 295.A O no hydrogen 3.153 N/A ASN 299.A ND2 LYS 295.A O no hydrogen 2.841 N/A ASP 300.A N LYS 296.A O no hydrogen 2.836 N/A GLY 301.A N VAL 297.A O no hydrogen 2.857 N/A LEU 302.A N LEU 298.A O no hydrogen 2.805 N/A ALA 303.A N ASN 299.A O no hydrogen 2.916 N/A GLU 304.A N ASP 300.A O no hydrogen 2.822 N/A LEU 305.A N GLY 301.A O no hydrogen 2.996 N/A GLU 306.A N ALA 303.A O no hydrogen 3.199 N/A ASN 307.A ND2 ALA 303.A O no hydrogen 3.140 N/A ASN 307.A ND2 GLU 304.A OE1 no hydrogen 3.452 N/A