Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 1ezx_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASN 6.A N ILE 3.A O no hydrogen 3.157 N/A ASN 6.A ND2 ASN 58.A O no hydrogen 2.819 N/A LEU 7.A N ILE 3.A O no hydrogen 3.125 N/A ALA 8.A N THR 4.A O no hydrogen 2.845 N/A GLU 9.A N PRO 5.A O no hydrogen 3.084 N/A PHE 10.A N ASN 6.A O no hydrogen 2.762 N/A ALA 11.A N LEU 7.A O no hydrogen 2.811 N/A PHE 12.A N ALA 8.A O no hydrogen 3.105 N/A SER 13.A N GLU 9.A O no hydrogen 3.012 N/A SER 13.A OG GLU 9.A O no hydrogen 2.882 N/A SER 13.A OG ASN 58.A OD1 no hydrogen 3.551 N/A LEU 14.A N PHE 10.A O no hydrogen 2.978 N/A TYR 15.A N ALA 11.A O no hydrogen 2.947 N/A TYR 15.A OH GLU 241.A OE2 no hydrogen 2.629 N/A ARG 16.A N PHE 12.A O no hydrogen 2.988 N/A ARG 16.A NE GLU 241.A O no hydrogen 3.029 N/A ARG 16.A NH2 GLU 241.A O no hydrogen 3.042 N/A ARG 16.A NH2 LEU 244.A O no hydrogen 2.962 N/A GLN 17.A N SER 13.A O no hydrogen 3.280 N/A LEU 18.A N LEU 14.A O no hydrogen 2.988 N/A ALA 19.A N TYR 15.A O no hydrogen 2.864 N/A HIS 20.A N ARG 16.A O no hydrogen 3.045 N/A GLN 21.A N GLN 17.A O no hydrogen 2.998 N/A SER 22.A N LEU 18.A O no hydrogen 3.317 N/A SER 22.A OG THR 25.A OG1 no hydrogen 3.251 N/A THR 25.A OG1 SER 22.A OG no hydrogen 3.251 N/A PHE 28.A N TYR 274.A OH no hydrogen 3.089 N/A SER 30.A N HIS 311.A NE2 no hydrogen 3.192 N/A SER 33.A N SER 30.A OG no hydrogen 3.348 N/A SER 33.A OG ASN 163.A OD1 no hydrogen 2.676 N/A ILE 34.A N SER 30.A O no hydrogen 3.257 N/A ALA 35.A N PRO 31.A O no hydrogen 2.766 N/A THR 36.A N VAL 32.A O no hydrogen 3.060 N/A THR 36.A OG1 VAL 32.A O no hydrogen 3.353 N/A THR 36.A OG1 SER 33.A O no hydrogen 3.522 N/A ALA 37.A N SER 33.A O no hydrogen 3.208 N/A PHE 38.A N ILE 34.A O no hydrogen 3.193 N/A ALA 39.A N ALA 35.A O no hydrogen 2.870 N/A MET 40.A N THR 36.A O no hydrogen 2.843 N/A LEU 41.A N ALA 37.A O no hydrogen 3.081 N/A SER 42.A N PHE 38.A O no hydrogen 3.028 N/A SER 42.A N ALA 39.A O no hydrogen 3.150 N/A SER 42.A OG ALA 39.A O no hydrogen 2.729 N/A LEU 43.A N MET 40.A O no hydrogen 3.188 N/A GLY 44.A N LEU 41.A O no hydrogen 3.228 N/A THR 45.A N SER 42.A O no hydrogen 3.116 N/A THR 45.A OG1 THR 49.A OG1 no hydrogen 2.935 N/A THR 45.A OG1 ASP 294.A O no hydrogen 3.075 N/A LYS 46.A N ASP 294.A O no hydrogen 3.128 N/A THR 49.A OG1 THR 45.A OG1 no hydrogen 2.935 N/A THR 49.A OG1 LYS 46.A O no hydrogen 2.928 N/A THR 49.A OG1 ASP 294.A O no hydrogen 3.243 N/A HIS 50.A N LYS 46.A O no hydrogen 3.317 N/A HIS 50.A ND1 ASP 51.A OD1 no hydrogen 3.008 N/A HIS 50.A NE2 GLU 66.A OE2 no hydrogen 2.561 N/A ASP 51.A N ALA 47.A O no hydrogen 3.225 N/A GLU 52.A N ASP 48.A O no hydrogen 3.022 N/A ILE 53.A N THR 49.A O no hydrogen 3.459 N/A LEU 54.A N HIS 50.A O no hydrogen 3.220 N/A GLU 55.A N ASP 51.A O no hydrogen 2.862 N/A GLY 56.A N GLU 52.A O no hydrogen 2.694 N/A LEU 57.A N LEU 54.A O no hydrogen 3.306 N/A ASN 58.A N GLU 55.A O no hydrogen 3.054 N/A PHE 59.A N LEU 54.A O no hydrogen 3.144 N/A THR 62.A N ASN 60.A OD1 no hydrogen 3.043 N/A THR 62.A OG1 ASN 60.A OD1 no hydrogen 2.937 N/A GLU 63.A N ASN 60.A O no hydrogen 3.127 N/A ILE 64.A N ASN 60.A O no hydrogen 3.193 N/A GLN 68.A N PRO 65.A O no hydrogen 2.678 N/A ILE 69.A N PRO 65.A O no hydrogen 3.281 N/A ILE 69.A N GLU 66.A O no hydrogen 3.286 N/A HIS 70.A N GLU 66.A O no hydrogen 3.451 N/A HIS 70.A ND1 TYR 115.A OH no hydrogen 2.820 N/A HIS 70.A NE2 GLU 66.A OE2 no hydrogen 3.358 N/A GLU 71.A N ALA 67.A O no hydrogen 3.011 N/A GLY 72.A N GLN 68.A O no hydrogen 2.902 N/A PHE 73.A N ILE 69.A O no hydrogen 3.050 N/A GLN 74.A N HIS 70.A O no hydrogen 3.055 N/A GLU 75.A N GLU 71.A O no hydrogen 2.991 N/A LEU 76.A N GLY 72.A O no hydrogen 2.813 N/A LEU 77.A N PHE 73.A O no hydrogen 2.812 N/A ARG 78.A N GLN 74.A O no hydrogen 3.186 N/A ARG 78.A NE GLU 75.A OE1 no hydrogen 3.350 N/A ARG 78.A NH2 GLU 75.A OE2 no hydrogen 2.902 N/A THR 79.A N GLU 75.A O no hydrogen 2.928 N/A THR 79.A OG1 GLU 75.A O no hydrogen 3.472 N/A LEU 80.A N LEU 76.A O no hydrogen 2.988 N/A ASN 81.A N LEU 77.A O no hydrogen 3.124 N/A ASN 81.A ND2 LEU 77.A O no hydrogen 3.073 N/A ASN 81.A ND2 THR 91.A OG1 no hydrogen 3.057 N/A GLN 82.A N THR 79.A O no hydrogen 3.070 N/A GLN 82.A NE2 ARG 78.A O no hydrogen 3.424 N/A ASP 84.A N ASN 224.A OD1 no hydrogen 3.053 N/A SER 85.A OG ASP 84.A OD2 no hydrogen 3.350 N/A GLN 86.A N ASP 84.A OD2 no hydrogen 2.445 N/A LEU 87.A N ASP 84.A O no hydrogen 2.824 N/A GLN 88.A N LYS 168.A O no hydrogen 3.092 N/A GLN 88.A NE2 GLN 143.A OE1 no hydrogen 3.246 N/A THR 90.A N PHE 166.A O no hydrogen 2.942 N/A THR 91.A N ASN 81.A OD1 no hydrogen 3.092 N/A GLY 92.A N TYR 164.A O no hydrogen 2.933 N/A ASN 93.A ND2 TYR 115.A O no hydrogen 2.882 N/A GLY 94.A N VAL 162.A O no hydrogen 2.652 N/A LEU 95.A N GLU 118.A O no hydrogen 2.933 N/A PHE 96.A N ALA 160.A O no hydrogen 2.842 N/A LEU 97.A N PHE 120.A O no hydrogen 2.806 N/A SER 98.A N VAL 158.A O no hydrogen 3.303 N/A SER 98.A OG VAL 158.A O no hydrogen 3.271 N/A GLU 99.A N VAL 122.A O no hydrogen 3.282 N/A LYS 102.A NZ ASP 105.A OD1 no hydrogen 3.393 N/A LYS 102.A NZ ASP 105.A OD2 no hydrogen 3.375 N/A VAL 104.A N VAL 298.A O no hydrogen 2.947 N/A LEU 108.A N VAL 104.A O no hydrogen 3.418 N/A GLU 109.A N ASP 105.A O no hydrogen 3.096 N/A ASP 110.A N LYS 106.A O no hydrogen 2.972 N/A VAL 111.A N PHE 107.A O no hydrogen 3.054 N/A LYS 112.A N LEU 108.A O no hydrogen 3.216 N/A LYS 113.A N GLU 109.A O no hydrogen 2.952 N/A LEU 114.A N ASP 110.A O no hydrogen 2.734 N/A TYR 115.A N VAL 111.A O no hydrogen 3.198 N/A TYR 115.A OH HIS 70.A ND1 no hydrogen 2.820 N/A HIS 116.A NE2 GLN 74.A O no hydrogen 3.130 N/A SER 117.A N VAL 111.A O no hydrogen 2.974 N/A SER 117.A OG GLU 118.A O no hydrogen 2.924 N/A GLU 118.A N ASN 93.A O no hydrogen 2.850 N/A PHE 120.A N LEU 95.A O no hydrogen 2.696 N/A VAL 122.A N LEU 97.A O no hydrogen 2.679 N/A GLY 125.A N ASN 123.A OD1 no hydrogen 3.080 N/A ASP 126.A N ASN 123.A O no hydrogen 3.200 N/A GLU 129.A N ASP 126.A OD1 no hydrogen 3.042 N/A ALA 130.A N ASP 126.A O no hydrogen 2.974 N/A LYS 131.A N THR 127.A O no hydrogen 2.786 N/A LYS 131.A NZ LYS 151.A O no hydrogen 3.039 N/A LYS 132.A N GLU 128.A O no hydrogen 3.108 N/A GLN 133.A N GLU 129.A O no hydrogen 3.059 N/A ILE 134.A N ALA 130.A O no hydrogen 3.193 N/A ASN 135.A N LYS 131.A O no hydrogen 3.069 N/A ASN 135.A ND2 VAL 150.A O no hydrogen 3.122 N/A ASP 136.A N LYS 132.A O no hydrogen 3.040 N/A TYR 137.A N GLN 133.A O no hydrogen 2.990 N/A TYR 137.A OH GLU 118.A OE2 no hydrogen 2.622 N/A VAL 138.A N ILE 134.A O no hydrogen 3.120 N/A GLU 139.A N ASN 135.A O no hydrogen 2.962 N/A LYS 140.A N ASP 136.A O no hydrogen 2.808 N/A GLY 141.A N TYR 137.A O no hydrogen 3.013 N/A THR 142.A N VAL 138.A O no hydrogen 2.885 N/A THR 142.A OG1 VAL 138.A O no hydrogen 2.975 N/A THR 142.A OG1 ILE 146.A O no hydrogen 3.517 N/A GLN 143.A N LYS 140.A O no hydrogen 3.206 N/A GLY 144.A N GLU 139.A O no hydrogen 2.826 N/A LYS 145.A N THR 142.A O no hydrogen 3.029 N/A LYS 145.A NZ GLU 323.A O no hydrogen 3.064 N/A ILE 146.A N THR 142.A OG1 no hydrogen 3.132 N/A VAL 150.A N ASN 135.A OD1 no hydrogen 2.788 N/A GLU 152.A N GLU 152.A OE1 no hydrogen 2.380 N/A ASP 154.A N GLU 331.A OE1 no hydrogen 3.109 N/A ASP 156.A N ASP 154.A OD2 no hydrogen 2.587 N/A THR 157.A N ASP 154.A O no hydrogen 3.330 N/A THR 157.A OG1 ASP 154.A O no hydrogen 2.881 N/A VAL 158.A N ALA 332.A O no hydrogen 2.907 N/A ALA 160.A N PHE 96.A O no hydrogen 2.896 N/A LEU 161.A N LEU 330.A O no hydrogen 2.813 N/A VAL 162.A N GLY 94.A O no hydrogen 2.887 N/A ASN 163.A N MET 328.A O no hydrogen 3.263 N/A ASN 163.A ND2 SER 33.A O no hydrogen 2.883 N/A TYR 164.A N GLY 92.A O no hydrogen 2.883 N/A ILE 165.A N GLY 326.A O no hydrogen 2.972 N/A PHE 166.A N THR 90.A O no hydrogen 2.787 N/A PHE 167.A N ALA 324.A O no hydrogen 2.816 N/A LYS 168.A N GLN 88.A O no hydrogen 2.974 N/A GLY 169.A N THR 322.A O no hydrogen 3.057 N/A TRP 171.A N LYS 320.A O no hydrogen 2.747 N/A TRP 171.A NE1 ASP 318.A O no hydrogen 2.985 N/A GLU 172.A N LYS 220.A O no hydrogen 3.104 N/A PHE 175.A N GLU 319.A O no hydrogen 2.984 N/A ASP 179.A N GLU 176.A O no hydrogen 2.892 N/A THR 180.A N VAL 177.A O no hydrogen 2.948 N/A THR 180.A OG1 VAL 177.A O no hydrogen 3.358 N/A THR 180.A OG1 GLU 319.A OE1 no hydrogen 2.596 N/A GLU 183.A N VAL 195.A O no hydrogen 3.017 N/A PHE 185.A N VAL 193.A O no hydrogen 2.847 N/A ASP 188.A N THR 191.A O no hydrogen 3.428 N/A VAL 190.A N ASP 188.A OD1 no hydrogen 2.714 N/A THR 191.A N ASP 188.A OD1 no hydrogen 2.823 N/A VAL 193.A N PHE 185.A O no hydrogen 2.952 N/A LYS 194.A NZ ASP 184.A OD1 no hydrogen 2.667 N/A VAL 195.A N GLU 183.A O no hydrogen 2.990 N/A MET 197.A N GLU 181.A O no hydrogen 2.705 N/A MET 198.A N LEU 265.A O no hydrogen 2.831 N/A LYS 199.A NZ GLU 181.A OE2 no hydrogen 2.929 N/A LYS 199.A NZ GLU 183.A OE2 no hydrogen 2.667 N/A ARG 200.A N LEU 263.A O no hydrogen 3.240 N/A GLY 202.A N ALA 261.A O no hydrogen 3.028 N/A PHE 204.A N ARG 259.A O no hydrogen 2.824 N/A GLN 207.A N VAL 216.A O no hydrogen 3.097 N/A HIS 208.A NE2 ASP 233.A OD1 no hydrogen 2.965 N/A HIS 208.A NE2 ASP 233.A OD2 no hydrogen 3.187 N/A CYS 209.A N SER 214.A O no hydrogen 3.253 N/A LEU 212.A N CYS 209.A O no hydrogen 3.204 N/A SER 214.A N CYS 209.A O no hydrogen 3.382 N/A SER 214.A OG LEU 212.A O no hydrogen 3.052 N/A TRP 215.A N LEU 231.A O no hydrogen 3.007 N/A VAL 216.A N GLN 207.A O no hydrogen 2.759 N/A LEU 217.A N PHE 229.A O no hydrogen 2.946 N/A LEU 218.A N ASN 205.A O no hydrogen 2.891 N/A MET 219.A N ALA 227.A O no hydrogen 2.940 N/A LYS 220.A NZ GLU 256.A OE2 no hydrogen 3.011 N/A TYR 221.A N ALA 225.A O no hydrogen 3.130 N/A TYR 221.A OH THR 322.A OG1 no hydrogen 2.824 N/A LEU 222.A N LYS 170.A O no hydrogen 2.850 N/A ALA 227.A N MET 219.A O no hydrogen 3.129 N/A PHE 229.A N LEU 217.A O no hydrogen 2.852 N/A LEU 231.A N TRP 215.A O no hydrogen 2.929 N/A ASP 233.A N SER 213.A O no hydrogen 2.786 N/A LYS 236.A N ASP 233.A O no hydrogen 2.911 N/A LEU 240.A N LYS 236.A O no hydrogen 2.952 N/A GLU 241.A N LEU 237.A O no hydrogen 2.990 N/A ASN 242.A N GLN 238.A O no hydrogen 3.187 N/A ASN 242.A N HIS 239.A O no hydrogen 3.204 N/A ASN 242.A ND2 GLN 238.A OE1 no hydrogen 2.895 N/A GLU 243.A N HIS 239.A O no hydrogen 3.047 N/A HIS 246.A N GLU 9.A OE2 no hydrogen 2.883 N/A ILE 249.A N THR 245.A O no hydrogen 3.381 N/A THR 250.A N HIS 246.A O no hydrogen 2.980 N/A THR 250.A OG1 HIS 246.A O no hydrogen 2.985 N/A LYS 251.A N ASP 247.A O no hydrogen 3.048 N/A PHE 252.A N ILE 248.A O no hydrogen 3.340 N/A LEU 253.A N ILE 249.A O no hydrogen 3.158 N/A GLU 254.A N LYS 251.A O no hydrogen 3.224 N/A ARG 258.A NH2 GLU 172.A OE1 no hydrogen 3.178 N/A ARG 259.A N PHE 204.A O no hydrogen 2.983 N/A ALA 261.A N GLY 202.A O no hydrogen 2.860 N/A LEU 263.A N ARG 200.A O no hydrogen 3.025 N/A LEU 265.A N MET 198.A O no hydrogen 2.984 N/A LYS 267.A N PRO 196.A O no hydrogen 3.165 N/A LYS 267.A NZ GLU 319.A OE2 no hydrogen 3.465 N/A LEU 268.A N ILE 317.A O no hydrogen 2.908 N/A SER 269.A OG LEU 268.A O no hydrogen 3.014 N/A ILE 270.A N LEU 315.A O no hydrogen 3.351 N/A THR 271.A OG1 ALA 313.A O no hydrogen 3.400 N/A GLY 272.A N ALA 313.A O no hydrogen 2.843 N/A TYR 274.A N HIS 311.A O no hydrogen 2.793 N/A LEU 276.A N ALA 309.A O no hydrogen 2.940 N/A LEU 280.A N LEU 276.A O no hydrogen 2.810 N/A GLY 281.A N LYS 277.A O no hydrogen 2.916 N/A GLN 282.A N SER 278.A O no hydrogen 2.962 N/A GLN 282.A NE2 SER 278.A O no hydrogen 3.640 N/A LEU 283.A N LEU 280.A O no hydrogen 2.879 N/A GLY 284.A N GLY 281.A O no hydrogen 2.960 N/A ILE 285.A N LEU 280.A O no hydrogen 3.122 N/A THR 286.A N GLU 52.A OE1 no hydrogen 3.113 N/A LYS 287.A N GLU 52.A OE1 no hydrogen 2.879 N/A LYS 287.A NZ GLY 292.A O no hydrogen 3.251 N/A PHE 289.A N THR 286.A O no hydrogen 3.113 N/A SER 290.A N LYS 287.A O no hydrogen 2.812 N/A SER 290.A OG LYS 287.A O no hydrogen 3.058 N/A GLY 292.A N SER 290.A OG no hydrogen 3.124 N/A ALA 293.A N SER 290.A O no hydrogen 3.084 N/A SER 296.A N ASP 294.A OD1 no hydrogen 3.061 N/A SER 296.A OG ASP 294.A OD1 no hydrogen 2.600 N/A VAL 298.A N LEU 295.A O no hydrogen 2.729 N/A THR 299.A OG1 LYS 102.A O no hydrogen 3.039 N/A GLU 301.A N THR 299.A OG1 no hydrogen 3.125 N/A LYS 305.A N ILE 333.A O no hydrogen 2.988 N/A LYS 305.A NZ ASN 291.A OD1 no hydrogen 3.143 N/A LEU 306.A N VAL 288.A O no hydrogen 2.995 N/A SER 307.A N GLU 331.A O no hydrogen 2.685 N/A SER 307.A OG GLU 331.A OE2 no hydrogen 2.928 N/A LYS 308.A N GLU 331.A O no hydrogen 3.484 N/A LYS 308.A NZ GLU 152.A O no hydrogen 2.629 N/A VAL 310.A N PHE 329.A O no hydrogen 2.906 N/A HIS 311.A N TYR 274.A O no hydrogen 3.007 N/A HIS 311.A ND1 ALA 327.A O no hydrogen 2.734 N/A LYS 312.A N ALA 327.A O no hydrogen 3.093 N/A LYS 312.A NZ ASP 148.A OD1 no hydrogen 2.494 N/A ALA 313.A N GLY 272.A O no hydrogen 2.905 N/A VAL 314.A N ALA 325.A O no hydrogen 2.876 N/A LEU 315.A N ILE 270.A O no hydrogen 2.988 N/A THR 316.A N GLU 323.A O no hydrogen 2.801 N/A ILE 317.A N LEU 268.A O no hydrogen 3.079 N/A ASP 318.A N GLY 321.A O no hydrogen 3.185 N/A LYS 320.A N ASP 318.A OD1 no hydrogen 2.924 N/A GLY 321.A N ASP 318.A OD1 no hydrogen 3.178 N/A THR 322.A N GLY 169.A O no hydrogen 3.036 N/A THR 322.A OG1 TYR 221.A OH no hydrogen 2.824 N/A GLU 323.A N THR 316.A O no hydrogen 2.902 N/A ALA 324.A N PHE 167.A O no hydrogen 2.933 N/A ALA 325.A N VAL 314.A O no hydrogen 3.143 N/A GLY 326.A N ILE 165.A O no hydrogen 2.984 N/A ALA 327.A N LYS 312.A O no hydrogen 2.815 N/A MET 328.A N ASN 163.A O no hydrogen 3.049 N/A PHE 329.A N VAL 310.A O no hydrogen 2.877 N/A LEU 330.A N LEU 161.A O no hydrogen 2.861 N/A GLU 331.A N LYS 308.A O no hydrogen 3.253 N/A ALA 332.A N PHE 159.A O no hydrogen 3.051 N/A ILE 333.A N LYS 305.A O no hydrogen 2.993 N/A MET 335.A N PRO 303.A O no hydrogen 2.973 N/A