Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 1fx4_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 4.A OG CYS 54.A O no hydrogen 2.770 N/A ALA 5.A N ASN 2.A O no hydrogen 2.940 N/A LYS 7.A NZ ASN 2.A O no hydrogen 2.717 N/A LYS 7.A NZ ASP 3.A O no hydrogen 3.233 N/A LYS 7.A NZ ALA 5.A O no hydrogen 2.730 N/A GLY 11.A N GLU 8.A O no hydrogen 2.861 N/A VAL 13.A N GLY 141.A O no hydrogen 2.767 N/A THR 14.A N SER 68.A O no hydrogen 3.152 N/A THR 14.A OG1 THR 140.A OG1 no hydrogen 2.822 N/A LEU 15.A N HIS 139.A O no hydrogen 2.812 N/A ILE 16.A N ILE 66.A O no hydrogen 2.746 N/A PHE 17.A N GLY 137.A O no hydrogen 2.946 N/A THR 18.A N PHE 64.A O no hydrogen 2.966 N/A ASP 19.A N ARG 135.A O no hydrogen 3.123 N/A ILE 20.A N ASP 19.A OD1 no hydrogen 2.874 N/A GLU 21.A N ARG 133.A O no hydrogen 2.713 N/A SER 23.A N ILE 20.A O no hydrogen 3.415 N/A SER 23.A OG ASP 62.A OD1 no hydrogen 3.462 N/A SER 23.A OG ASP 62.A OD2 no hydrogen 2.966 N/A LEU 26.A N SER 22.A O no hydrogen 2.959 N/A TRP 27.A N SER 23.A O no hydrogen 2.795 N/A ALA 28.A N THR 24.A O no hydrogen 3.072 N/A ALA 29.A N ALA 25.A O no hydrogen 2.965 N/A HIS 30.A N LEU 26.A O no hydrogen 2.662 N/A HIS 30.A NE2 SER 98.A OG no hydrogen 2.569 N/A LEU 33.A N HIS 30.A O no hydrogen 2.905 N/A MET 34.A N HIS 30.A O no hydrogen 2.941 N/A ALA 37.A N LEU 33.A O no hydrogen 3.050 N/A VAL 38.A N MET 34.A O no hydrogen 2.825 N/A ALA 39.A N PRO 35.A O no hydrogen 3.034 N/A THR 40.A N ASP 36.A O no hydrogen 2.896 N/A THR 40.A OG1 ASP 36.A O no hydrogen 2.914 N/A HIS 41.A N ALA 37.A O no hydrogen 2.884 N/A HIS 41.A ND1 HIS 42.A ND1 no hydrogen 2.914 N/A HIS 42.A N VAL 38.A O no hydrogen 2.887 N/A HIS 42.A ND1 HIS 41.A ND1 no hydrogen 2.914 N/A ARG 43.A N ALA 39.A O no hydrogen 3.046 N/A LEU 44.A N THR 40.A O no hydrogen 2.846 N/A ILE 45.A N HIS 41.A O no hydrogen 2.985 N/A ARG 46.A N HIS 42.A O no hydrogen 2.929 N/A ARG 46.A NE GLU 56.A OE2 no hydrogen 2.942 N/A ARG 46.A NH2 GLU 56.A OE1 no hydrogen 2.906 N/A SER 47.A N ARG 43.A O no hydrogen 3.056 N/A SER 47.A OG ARG 43.A O no hydrogen 2.893 N/A LEU 48.A N LEU 44.A O no hydrogen 3.164 N/A ILE 49.A N ILE 45.A O no hydrogen 2.893 N/A THR 50.A N ARG 46.A O no hydrogen 3.090 N/A THR 50.A OG1 ARG 46.A O no hydrogen 3.189 N/A ARG 51.A N SER 47.A O no hydrogen 2.879 N/A TYR 52.A N LEU 48.A O no hydrogen 2.853 N/A GLU 53.A N THR 50.A O no hydrogen 3.129 N/A CYS 54.A N ILE 49.A O no hydrogen 2.898 N/A CYS 54.A SG TYR 52.A O no hydrogen 3.609 N/A TYR 55.A N ALA 67.A O no hydrogen 2.765 N/A TYR 55.A OH ASN 2.A OD1 no hydrogen 2.946 N/A VAL 57.A N MET 65.A O no hydrogen 2.872 N/A LYS 58.A N MET 65.A O no hydrogen 3.497 N/A LYS 58.A NZ ASP 155.A OD1 no hydrogen 2.633 N/A LYS 58.A NZ ASP 155.A OD2 no hydrogen 3.393 N/A THR 59.A OG1 GLU 56.A OE1 no hydrogen 3.415 N/A VAL 60.A N SER 63.A O no hydrogen 2.910 N/A SER 63.A N VAL 60.A O no hydrogen 2.907 N/A SER 63.A OG THR 18.A O no hydrogen 2.778 N/A PHE 64.A N THR 18.A O no hydrogen 3.183 N/A PHE 64.A N THR 18.A OG1 no hydrogen 3.106 N/A MET 65.A N LYS 58.A O no hydrogen 2.995 N/A ILE 66.A N ILE 16.A O no hydrogen 2.808 N/A ALA 67.A N TYR 55.A O no hydrogen 2.827 N/A SER 68.A N THR 14.A O no hydrogen 2.852 N/A SER 68.A OG SER 70.A O no hydrogen 2.687 N/A LYS 69.A NZ ASP 3.A O no hydrogen 2.775 N/A SER 70.A N SER 68.A OG no hydrogen 3.088 N/A ALA 73.A N SER 70.A OG no hydrogen 3.007 N/A ALA 74.A N SER 70.A O no hydrogen 3.198 N/A VAL 75.A N PRO 71.A O no hydrogen 3.138 N/A GLN 76.A N PHE 72.A O no hydrogen 2.892 N/A LEU 77.A N ALA 73.A O no hydrogen 2.922 N/A ALA 78.A N ALA 74.A O no hydrogen 3.056 N/A GLN 79.A N VAL 75.A O no hydrogen 2.954 N/A GLU 80.A N GLN 76.A O no hydrogen 2.850 N/A LEU 81.A N LEU 77.A O no hydrogen 2.767 N/A GLN 82.A N ALA 78.A O no hydrogen 3.227 N/A GLN 82.A NE2 VAL 134.A O no hydrogen 2.827 N/A LEU 83.A N GLN 79.A O no hydrogen 3.173 N/A CYS 84.A N GLU 80.A O no hydrogen 2.761 N/A CYS 84.A SG GLU 80.A O no hydrogen 3.154 N/A CYS 84.A SG GLU 80.A OE1 no hydrogen 3.854 N/A PHE 85.A N LEU 81.A O no hydrogen 3.012 N/A LEU 86.A N GLN 82.A O no hydrogen 3.014 N/A ARG 87.A N LEU 83.A O no hydrogen 2.925 N/A LEU 88.A N CYS 84.A O no hydrogen 2.970 N/A TRP 90.A NE1 PHE 85.A O no hydrogen 2.903 N/A GLU 91.A N ASP 89.A OD1 no hydrogen 2.797 N/A ALA 94.A N THR 92.A OG1 no hydrogen 3.044 N/A GLU 97.A N ASN 93.A O no hydrogen 3.006 N/A SER 98.A N ALA 94.A O no hydrogen 3.018 N/A SER 98.A OG HIS 30.A NE2 no hydrogen 2.569 N/A SER 98.A OG ALA 94.A O no hydrogen 3.232 N/A TYR 99.A N VAL 95.A O no hydrogen 2.906 N/A TYR 99.A OH GLU 21.A O no hydrogen 2.819 N/A ARG 100.A N ASP 96.A O no hydrogen 2.953 N/A GLU 101.A N GLU 97.A O no hydrogen 2.930 N/A PHE 102.A N SER 98.A O no hydrogen 2.858 N/A GLU 103.A N TYR 99.A O no hydrogen 3.200 N/A GLU 104.A N ARG 100.A O no hydrogen 3.054 N/A GLN 105.A N GLU 101.A O no hydrogen 2.782 N/A ARG 106.A N PHE 102.A O no hydrogen 2.934 N/A ARG 106.A NE GLU 110.A OE1 no hydrogen 3.189 N/A ARG 106.A NE GLU 110.A OE2 no hydrogen 2.823 N/A ARG 106.A NH2 GLU 110.A OE1 no hydrogen 3.410 N/A ARG 106.A NH2 GLU 110.A OE2 no hydrogen 3.517 N/A ALA 107.A N GLU 103.A O no hydrogen 2.841 N/A GLU 108.A N GLU 104.A O no hydrogen 3.236 N/A THR 117.A N GLU 103.A OE2 no hydrogen 2.911 N/A THR 117.A OG1 GLU 103.A OE1 no hydrogen 2.694 N/A THR 117.A OG1 GLU 103.A OE2 no hydrogen 3.302 N/A ALA 118.A N GLU 103.A OE2 no hydrogen 2.842 N/A LEU 120.A N THR 117.A O no hydrogen 3.094 N/A TYR 125.A N ASP 121.A O no hydrogen 2.797 N/A TYR 125.A OH ASP 96.A OD1 no hydrogen 2.619 N/A SER 126.A N PRO 122.A O no hydrogen 3.180 N/A SER 126.A OG GLU 123.A O no hydrogen 3.330 N/A ARG 127.A N VAL 124.A O no hydrogen 3.255 N/A LEU 128.A N TYR 125.A O no hydrogen 2.971 N/A TRP 129.A N TYR 125.A O no hydrogen 2.744 N/A ASN 130.A ND2 LEU 86.A O no hydrogen 2.893 N/A ASN 130.A ND2 LEU 88.A O no hydrogen 2.652 N/A GLY 131.A N ASP 96.A OD2 no hydrogen 2.785 N/A ARG 133.A N TYR 99.A OH no hydrogen 2.940 N/A ARG 133.A NH1 GLU 103.A OE1 no hydrogen 3.066 N/A ARG 133.A NH2 THR 117.A OG1 no hydrogen 2.938 N/A ARG 133.A NH2 TYR 125.A OH no hydrogen 2.862 N/A ARG 135.A N ASP 19.A O no hydrogen 2.853 N/A ARG 135.A NH1 GLU 168.A OE1 no hydrogen 3.410 N/A VAL 136.A N GLN 175.A O no hydrogen 2.934 N/A GLY 137.A N PHE 17.A O no hydrogen 2.974 N/A ILE 138.A N LEU 177.A O no hydrogen 2.786 N/A HIS 139.A N LEU 15.A O no hydrogen 3.085 N/A HIS 139.A ND1 THR 160.A O no hydrogen 3.345 N/A THR 140.A OG1 THR 14.A OG1 no hydrogen 2.822 N/A GLY 141.A N VAL 13.A O no hydrogen 2.935 N/A CYS 143.A SG GLY 141.A O no hydrogen 3.860 N/A ASP 144.A N TYR 157.A O no hydrogen 3.100 N/A ARG 146.A N ASP 155.A O no hydrogen 2.837 N/A ASP 148.A N GLY 153.A O no hydrogen 2.758 N/A THR 151.A OG1 ASP 148.A OD2 no hydrogen 3.073 N/A GLY 153.A N THR 151.A OG1 no hydrogen 2.922 N/A TYR 154.A N TYR 55.A OH no hydrogen 2.889 N/A ASP 155.A N ARG 146.A O no hydrogen 2.726 N/A TYR 156.A N ASP 155.A OD2 no hydrogen 2.674 N/A TYR 156.A OH PRO 6.A O no hydrogen 2.707 N/A TYR 157.A N ASP 144.A O no hydrogen 2.948 N/A THR 160.A OG1 LEU 142.A O no hydrogen 2.595 N/A SER 161.A OG TYR 156.A O no hydrogen 3.148 N/A ASN 162.A N GLY 158.A O no hydrogen 3.128 N/A MET 163.A N ARG 159.A O no hydrogen 2.726 N/A ALA 164.A N THR 160.A O no hydrogen 3.061 N/A ALA 165.A N SER 161.A O no hydrogen 2.993 N/A ARG 166.A N ASN 162.A O no hydrogen 2.928 N/A THR 167.A N MET 163.A O no hydrogen 3.001 N/A THR 167.A OG1 MET 163.A O no hydrogen 2.818 N/A GLU 168.A N ALA 164.A O no hydrogen 3.084 N/A SER 169.A N ALA 165.A O no hydrogen 2.959 N/A SER 169.A OG ARG 166.A O no hydrogen 2.797 N/A VAL 170.A N ARG 166.A O no hydrogen 3.284 N/A VAL 170.A N THR 167.A O no hydrogen 3.301 N/A ALA 171.A N GLU 168.A O no hydrogen 3.009 N/A ASN 172.A ND2 ALA 226.A O no hydrogen 3.231 N/A GLY 173.A N GLU 21.A OE1 no hydrogen 2.752 N/A GLY 174.A N VAL 134.A O no hydrogen 2.871 N/A GLN 175.A N ASN 172.A O no hydrogen 3.045 N/A LEU 177.A N VAL 136.A O no hydrogen 2.861 N/A MET 178.A N TYR 214.A O no hydrogen 2.773 N/A THR 179.A N ILE 138.A O no hydrogen 3.067 N/A HIS 180.A ND1 TYR 214.A OH no hydrogen 3.356 N/A ALA 182.A N THR 179.A OG1 no hydrogen 3.139 N/A TYR 183.A N THR 179.A O no hydrogen 2.907 N/A MET 184.A N HIS 180.A O no hydrogen 2.768 N/A SER 185.A N ALA 182.A O no hydrogen 2.964 N/A SER 185.A OG ALA 181.A O no hydrogen 2.569 N/A LEU 186.A N TYR 183.A O no hydrogen 3.321 N/A ASP 190.A N SER 187.A OG no hydrogen 3.198 N/A ARG 191.A N SER 187.A O no hydrogen 3.026 N/A ASN 192.A N GLY 188.A O no hydrogen 3.211 N/A GLN 193.A N ASP 190.A O no hydrogen 3.095 N/A LEU 194.A N ARG 191.A O no hydrogen 3.206 N/A THR 197.A N GLN 215.A O no hydrogen 2.758 N/A THR 197.A OG1 ASN 217.A OD1 no hydrogen 2.915 N/A LEU 199.A N MET 213.A O no hydrogen 2.903 N/A THR 202.A N VAL 211.A O no hydrogen 2.737 N/A THR 202.A OG1 GLY 200.A O no hydrogen 3.210 N/A VAL 207.A N LEU 204.A O no hydrogen 3.056 N/A VAL 211.A N THR 202.A O no hydrogen 2.707 N/A MET 213.A N GLY 200.A O no hydrogen 3.020 N/A TYR 214.A N MET 178.A O no hydrogen 2.805 N/A TYR 214.A OH HIS 180.A ND1 no hydrogen 3.356 N/A GLN 215.A N THR 197.A O no hydrogen 2.706 N/A GLN 215.A NE2 GLN 175.A OE1 no hydrogen 2.841 N/A LEU 216.A N VAL 176.A O no hydrogen 2.978 N/A ASN 217.A N ASP 195.A O no hydrogen 2.785 N/A ASN 217.A ND2 GLN 215.A OE1 no hydrogen 2.791 N/A ALA 218.A N LEU 216.A O no hydrogen 2.886 N/A ARG 222.A N VAL 219.A O no hydrogen 3.341 N/A ARG 222.A NE LEU 128.A O no hydrogen 2.747 N/A ARG 222.A NH1 GLN 82.A OE1 no hydrogen 2.994 N/A ARG 222.A NH1 GLY 174.A O no hydrogen 3.062 N/A ARG 222.A NH2 LEU 128.A O no hydrogen 2.852 N/A ARG 228.A N VAL 170.A O no hydrogen 2.839 N/A ARG 228.A NE SER 169.A O no hydrogen 2.685 N/A LEU 229.A N LEU 227.A O no hydrogen 2.693 N/A