Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 1i6l_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 2.A N ASP 135.A OD2 no hydrogen 2.803 N/A ILE 3.A N ASN 33.A O no hydrogen 2.745 N/A PHE 4.A N ILE 136.A O no hydrogen 3.230 N/A SER 5.A N TYR 35.A O no hydrogen 3.073 N/A SER 5.A OG PRO 138.A O no hydrogen 2.677 N/A ILE 7.A N CYS 37.A O no hydrogen 3.019 N/A GLN 8.A NE2 TYR 122.A OH no hydrogen 2.837 N/A SER 10.A OG VAL 12.A O no hydrogen 2.927 N/A THR 14.A N ASN 17.A OD1 no hydrogen 2.878 N/A THR 14.A OG1 ASN 17.A OD1 no hydrogen 3.457 N/A ILE 15.A N ILE 198.A O no hydrogen 2.857 N/A GLY 16.A N THR 14.A OG1 no hydrogen 2.805 N/A ASN 17.A N THR 14.A OG1 no hydrogen 3.083 N/A TYR 18.A N THR 14.A O no hydrogen 3.061 N/A ILE 19.A N ILE 15.A O no hydrogen 2.864 N/A GLY 20.A N GLY 16.A O no hydrogen 2.955 N/A ALA 21.A N ASN 17.A O no hydrogen 3.086 N/A LEU 22.A N ASN 17.A O no hydrogen 3.110 N/A ARG 23.A N TYR 18.A O no hydrogen 2.865 N/A ARG 23.A NE ILE 19.A O no hydrogen 2.882 N/A ARG 23.A NH2 ILE 19.A O no hydrogen 2.958 N/A ARG 23.A NH2 VAL 175.A O no hydrogen 3.145 N/A GLN 24.A NE2 GLY 20.A O no hydrogen 2.851 N/A GLN 24.A NE2 VAL 139.A O no hydrogen 3.302 N/A GLN 24.A NE2 ARG 171.A O no hydrogen 3.280 N/A PHE 25.A N ALA 21.A O no hydrogen 3.067 N/A VAL 26.A N LEU 22.A O no hydrogen 3.137 N/A GLU 27.A N ARG 23.A O no hydrogen 3.088 N/A LEU 28.A N GLN 24.A O no hydrogen 2.928 N/A GLN 29.A N PHE 25.A O no hydrogen 2.978 N/A GLN 29.A NE2 GLY 68.A O no hydrogen 2.984 N/A HIS 30.A ND1.A GLN 73.A OE1 no hydrogen 2.684 N/A GLU 31.A N LEU 28.A O no hydrogen 3.059 N/A ASN 33.A N LYS 1.A O no hydrogen 2.920 N/A ASN 33.A ND2 LYS 1.A O no hydrogen 3.557 N/A CYS 34.A SG TYR 32.A O no hydrogen 3.512 N/A TYR 35.A N ILE 3.A O no hydrogen 2.917 N/A PHE 36.A N THR 75.A O no hydrogen 2.888 N/A CYS 37.A N SER 5.A O no hydrogen 2.973 N/A CYS 37.A SG PHE 77.A O no hydrogen 3.765 N/A ILE 38.A N PHE 77.A O no hydrogen 2.897 N/A VAL 39.A N ILE 7.A O no hydrogen 3.049 N/A ASP 40.A N ILE 38.A O no hydrogen 3.018 N/A HIS 42.A N GLN 79.A OE1 no hydrogen 3.207 N/A HIS 42.A NE2 TYR 122.A O no hydrogen 3.102 N/A ALA 43.A N VAL 39.A O no hydrogen 3.005 N/A ILE 44.A N ASP 40.A O no hydrogen 3.258 N/A THR 45.A N HIS 42.A O no hydrogen 3.051 N/A THR 45.A OG1 HIS 42.A O no hydrogen 2.875 N/A VAL 46.A N ALA 43.A O no hydrogen 3.461 N/A GLN 48.A NE2 ALA 43.A O no hydrogen 2.948 N/A GLU 52.A N ASP 49.A OD2 no hydrogen 2.958 N/A LEU 53.A N ASP 49.A O no hydrogen 2.874 N/A ARG 54.A N PRO 50.A O no hydrogen 3.043 N/A GLN 55.A N HIS 51.A O no hydrogen 3.079 N/A ASN 56.A N GLU 52.A O no hydrogen 2.753 N/A ILE 57.A N LEU 53.A O no hydrogen 2.863 N/A ARG 58.A N ARG 54.A O no hydrogen 3.229 N/A ARG 58.A NH1 ASP 290.A OD1 no hydrogen 2.955 N/A ARG 58.A NH1 ASP 290.A OD2 no hydrogen 3.491 N/A ARG 58.A NH2 ASP 290.A OD2 no hydrogen 3.098 N/A ARG 59.A N GLN 55.A O no hydrogen 2.834 N/A ARG 59.A NH2 TYR 281.A OH no hydrogen 3.286 N/A LEU 60.A N ASN 56.A O no hydrogen 2.956 N/A ALA 61.A N ILE 57.A O no hydrogen 3.141 N/A ALA 62.A N ARG 58.A O no hydrogen 2.925 N/A LEU 63.A N ARG 59.A O no hydrogen 2.839 N/A TYR 64.A N LEU 60.A O no hydrogen 2.899 N/A TYR 64.A OH CYS 37.A O no hydrogen 2.800 N/A LEU 65.A N ALA 61.A O no hydrogen 3.109 N/A ALA 66.A N ALA 62.A O no hydrogen 2.755 N/A VAL 67.A N LEU 63.A O no hydrogen 2.935 N/A GLY 68.A N LEU 65.A O no hydrogen 2.957 N/A ILE 69.A N TYR 64.A O no hydrogen 3.089 N/A ASP 70.A N GLN 29.A OE1 no hydrogen 2.795 N/A THR 72.A N ASP 70.A OD1 no hydrogen 2.840 N/A THR 72.A OG1 ASP 70.A OD1 no hydrogen 2.767 N/A THR 72.A OG1 ASP 70.A OD2 no hydrogen 3.357 N/A GLN 73.A N ASP 70.A O no hydrogen 2.814 N/A GLN 73.A NE2 THR 72.A OG1 no hydrogen 2.999 N/A ALA 74.A N ASP 70.A O no hydrogen 2.926 N/A THR 75.A N CYS 34.A O no hydrogen 2.808 N/A PHE 77.A N PHE 36.A O no hydrogen 3.122 N/A GLN 79.A N ILE 38.A O no hydrogen 2.886 N/A GLN 79.A NE2 HIS 42.A ND1 no hydrogen 3.169 N/A GLN 79.A NE2 ASP 128.A OD2 no hydrogen 2.798 N/A SER 80.A N ASP 40.A OD1 no hydrogen 2.780 N/A SER 80.A OG ASP 40.A OD1 no hydrogen 3.386 N/A SER 80.A OG ASP 40.A OD2 no hydrogen 2.554 N/A GLU 81.A N ILE 78.A O no hydrogen 2.973 N/A VAL 82.A N GLN 79.A O no hydrogen 3.072 N/A HIS 85.A N VAL 82.A O no hydrogen 3.047 N/A GLN 87.A N PRO 83.A O no hydrogen 3.116 N/A ALA 88.A N ALA 84.A O no hydrogen 2.838 N/A ALA 89.A N HIS 85.A O no hydrogen 2.859 N/A TRP 90.A N ALA 86.A O no hydrogen 3.094 N/A GLN 92.A N ALA 89.A O no hydrogen 2.822 N/A GLN 92.A NE2.A ALA 89.A O no hydrogen 3.461 N/A CYS 93.A N TRP 90.A O no hydrogen 3.130 N/A CYS 93.A SG TRP 90.A O no hydrogen 3.513 N/A ILE 94.A N LEU 91.A O no hydrogen 2.970 N/A VAL 95.A N LEU 91.A O no hydrogen 2.994 N/A TYR 96.A N GLU 99.A OE1 no hydrogen 2.944 N/A LEU 100.A N TYR 96.A O no hydrogen 3.284 N/A GLU 101.A N ILE 97.A O no hydrogen 3.008 N/A ARG 102.A N GLY 98.A O no hydrogen 3.190 N/A THR 103.A OG1 GLN 145.A OE1 no hydrogen 3.257 N/A GLU 107.A N THR 103.A O no hydrogen 2.824 N/A LYS 108.A N GLN 104.A O no hydrogen 2.963 N/A SER 109.A N PHE 105.A O no hydrogen 3.032 N/A SER 109.A OG PHE 105.A O no hydrogen 2.983 N/A SER 109.A OG LYS 106.A O no hydrogen 3.520 N/A ALA 110.A N GLU 107.A O no hydrogen 3.444 N/A LYS 112.A N SER 109.A O no hydrogen 3.057 N/A LEU 119.A N SER 116.A O no hydrogen 3.211 N/A THR 121.A N ALA 117.A O no hydrogen 3.064 N/A THR 121.A OG1 ALA 117.A O no hydrogen 3.118 N/A ALA 127.A N PRO 124.A O no hydrogen 2.909 N/A ASP 128.A N LEU 125.A O no hydrogen 2.901 N/A LEU 130.A N ALA 126.A O no hydrogen 2.912 N/A LEU 131.A N ALA 127.A O no hydrogen 2.979 N/A TYR 132.A N ILE 129.A O no hydrogen 3.400 N/A ASN 133.A N LEU 130.A O no hydrogen 3.165 N/A THR 134.A OG1 ILE 129.A O no hydrogen 2.641 N/A ASP 135.A N THR 2.A O no hydrogen 2.877 N/A ILE 136.A N THR 2.A O no hydrogen 3.033 N/A VAL 137.A N GLU 169.A O no hydrogen 2.941 N/A VAL 139.A N ARG 171.A O no hydrogen 3.095 N/A GLU 141.A N ALA 177.A O no hydrogen 2.931 N/A GLN 143.A N GLY 140.A O no hydrogen 3.179 N/A GLN 143.A NE2 ASP 142.A OD1 no hydrogen 2.907 N/A LYS 144.A N GLU 141.A O no hydrogen 3.092 N/A LYS 144.A NZ GLU 141.A OE2 no hydrogen 3.173 N/A GLN 145.A NE2 ARG 102.A O no hydrogen 3.491 N/A HIS 146.A ND1 GLN 143.A OE1 no hydrogen 2.808 N/A ILE 147.A N GLN 143.A O no hydrogen 3.015 N/A GLU 148.A N LYS 144.A O no hydrogen 2.952 N/A LEU 149.A N GLN 145.A O no hydrogen 2.972 N/A THR 150.A N HIS 146.A O no hydrogen 2.934 N/A THR 150.A OG1 HIS 146.A O no hydrogen 2.951 N/A ARG 151.A N ILE 147.A O no hydrogen 2.878 N/A ARG 151.A NH1 PRO 168.A O no hydrogen 2.793 N/A ASP 152.A N GLU 148.A O no hydrogen 3.022 N/A LEU 153.A N LEU 149.A O no hydrogen 2.808 N/A ALA 154.A N THR 150.A O no hydrogen 2.970 N/A GLU 155.A N ARG 151.A O no hydrogen 2.937 N/A ARG 156.A N ASP 152.A O no hydrogen 2.872 N/A ARG 156.A NH1 ILE 94.A O no hydrogen 2.796 N/A ARG 156.A NH1 GLU 99.A OE1 no hydrogen 2.905 N/A ARG 156.A NH2 GLU 99.A OE1 no hydrogen 3.511 N/A ARG 156.A NH2 GLU 99.A OE2 no hydrogen 2.730 N/A PHE 157.A N LEU 153.A O no hydrogen 2.765 N/A ASN 158.A N ALA 154.A O no hydrogen 2.883 N/A ASN 158.A ND2 PHE 165.A O no hydrogen 2.947 N/A LYS 159.A N GLU 155.A O no hydrogen 2.933 N/A ARG 160.A N ARG 156.A O no hydrogen 3.025 N/A TYR 161.A N PHE 157.A O no hydrogen 2.883 N/A GLY 162.A N ASN 158.A O no hydrogen 3.077 N/A LEU 164.A N ASN 158.A OD1 no hydrogen 2.958 N/A PHE 165.A N ASN 158.A OD1 no hydrogen 2.978 N/A THR 166.A OG1 ASN 133.A OD1 no hydrogen 2.607 N/A GLU 169.A N ASP 135.A O no hydrogen 2.943 N/A ARG 171.A N VAL 137.A O no hydrogen 2.986 N/A ARG 171.A NH1 GLU 27.A OE1 no hydrogen 3.367 N/A ARG 171.A NH2 GLN 24.A OE1 no hydrogen 2.938 N/A ARG 171.A NH2 GLU 27.A OE2 no hydrogen 3.162 N/A SER 180.A N LYS 186.A O no hydrogen 2.762 N/A LEU 181.A N ALA 196.A O no hydrogen 3.035 N/A VAL 182.A N SER 180.A OG no hydrogen 3.000 N/A ASP 183.A N SER 180.A OG no hydrogen 3.003 N/A THR 185.A N ASP 183.A OD1 no hydrogen 2.987 N/A THR 185.A OG1 ASP 183.A OD1 no hydrogen 2.652 N/A THR 185.A OG1 ASP 183.A OD2 no hydrogen 3.488 N/A LYS 186.A N ASP 183.A O no hydrogen 2.996 N/A LYS 189.A NZ.B SER 10.A OG no hydrogen 3.252 N/A SER 190.A N SER 188.A OG no hydrogen 3.051 N/A SER 190.A OG SER 188.A OG no hydrogen 3.275 N/A ASP 191.A N SER 188.A O no hydrogen 3.110 N/A ASN 193.A N ASP 191.A OD1 no hydrogen 2.949 N/A LYS 195.A N ASN 193.A OD1 no hydrogen 3.118 N/A LYS 195.A NZ SER 213.A OG no hydrogen 2.463 N/A ALA 196.A N ASN 193.A O no hydrogen 2.869 N/A THR 199.A N ASP 202.A OD2 no hydrogen 3.095 N/A THR 199.A OG1 ASP 202.A OD1 no hydrogen 2.695 N/A LEU 200.A N ILE 13.A O no hydrogen 2.940 N/A LEU 201.A N THR 199.A OG1 no hydrogen 3.044 N/A ASP 202.A N THR 199.A O no hydrogen 3.135 N/A THR 206.A N ASP 203.A OD1 no hydrogen 2.845 N/A THR 206.A OG1 ASP 203.A OD1 no hydrogen 2.675 N/A ILE 207.A N ASP 203.A O no hydrogen 2.926 N/A GLU 208.A N ALA 204.A O no hydrogen 3.042 N/A LYS 209.A N LYS 205.A O no hydrogen 3.004 N/A LYS 210.A N THR 206.A O no hydrogen 2.978 N/A LYS 210.A NZ PRO 194.A O no hydrogen 3.031 N/A LYS 210.A NZ TYR 197.A O no hydrogen 2.878 N/A LYS 210.A NZ ASP 202.A OD2 no hydrogen 2.752 N/A ILE 211.A N ILE 207.A O no hydrogen 2.978 N/A LYS 212.A N GLU 208.A O no hydrogen 2.875 N/A SER 213.A N LYS 209.A O no hydrogen 3.008 N/A SER 213.A OG LYS 209.A O no hydrogen 3.108 N/A ALA 214.A N ILE 211.A O no hydrogen 3.101 N/A VAL 215.A N LEU 181.A O no hydrogen 2.910 N/A GLU 219.A N ASP 217.A OD1 no hydrogen 2.741 N/A THR 221.A N TYR 259.A OH no hydrogen 3.135 N/A THR 221.A OG1 GLU 219.A O no hydrogen 3.311 N/A ARG 223.A NH1 ASP 225.A OD2 no hydrogen 3.170 N/A ARG 223.A NH2 ASP 225.A OD2 no hydrogen 2.982 N/A TYR 224.A N GLU 251.A OE1 no hydrogen 2.789 N/A ASP 225.A N SER 233.A OG no hydrogen 2.783 N/A ALA 228.A N ASP 225.A OD1 no hydrogen 2.945 N/A LYS 229.A N ASP 225.A O no hydrogen 2.710 N/A LYS 229.A NZ ASP 217.A OD1 no hydrogen 3.401 N/A LYS 229.A NZ ASP 217.A OD2 no hydrogen 2.853 N/A LYS 229.A NZ GLU 219.A OE2 no hydrogen 3.117 N/A LYS 229.A NZ THR 221.A O no hydrogen 2.875 N/A LYS 229.A NZ TYR 259.A OH no hydrogen 2.986 N/A SER 233.A N LYS 229.A O no hydrogen 2.981 N/A SER 233.A OG LYS 229.A O no hydrogen 2.581 N/A ASN 234.A N PRO 230.A O no hydrogen 2.958 N/A LEU 235.A N GLY 231.A O no hydrogen 3.061 N/A LEU 236.A N ILE 232.A O no hydrogen 2.875 N/A ASN 237.A N SER 233.A O no hydrogen 2.969 N/A ASN 237.A ND2 TYR 224.A OH no hydrogen 3.234 N/A ILE 238.A N ASN 234.A O no hydrogen 3.021 N/A TYR 239.A N LEU 235.A O no hydrogen 2.818 N/A TYR 239.A OH TYR 254.A OH no hydrogen 2.668 N/A SER 240.A N LEU 236.A O no hydrogen 2.771 N/A SER 240.A OG GLN 245.A O no hydrogen 2.560 N/A THR 241.A N ASN 237.A O no hydrogen 2.974 N/A THR 241.A OG1 ASN 237.A O no hydrogen 2.855 N/A THR 241.A OG1 ILE 238.A O no hydrogen 3.130 N/A LEU 242.A N ILE 238.A O no hydrogen 3.019 N/A SER 243.A N TYR 239.A O no hydrogen 2.965 N/A SER 243.A OG TYR 239.A O no hydrogen 2.888 N/A GLY 244.A N SER 240.A O no hydrogen 2.892 N/A GLN 245.A N SER 243.A OG no hydrogen 3.078 N/A GLN 245.A NE2 GLN 253.A OE1 no hydrogen 3.505 N/A SER 246.A N GLU 249.A OE2 no hydrogen 3.222 N/A GLU 249.A N SER 246.A OG no hydrogen 2.834 N/A LEU 250.A N SER 246.A O no hydrogen 3.040 N/A GLU 251.A N ILE 247.A O no hydrogen 2.914 N/A ARG 252.A N GLU 248.A O no hydrogen 3.034 N/A GLN 253.A N GLU 249.A O no hydrogen 2.866 N/A TYR 254.A N LEU 250.A O no hydrogen 2.999 N/A TYR 254.A OH TYR 239.A OH no hydrogen 2.668 N/A TYR 254.A OH ASP 265.A OD1 no hydrogen 2.705 N/A GLU 255.A N ARG 252.A O no hydrogen 3.054 N/A LYS 257.A N TYR 254.A O no hydrogen 2.805 N/A TYR 259.A OH ASP 217.A OD1 no hydrogen 2.506 N/A TYR 259.A OH ASP 217.A OD2 no hydrogen 3.408 N/A TYR 259.A OH THR 221.A O no hydrogen 3.302 N/A PHE 262.A N GLY 258.A O no hydrogen 3.432 N/A LYS 263.A N TYR 259.A O no hydrogen 2.784 N/A LYS 263.A NZ LYS 212.A O no hydrogen 2.697 N/A LYS 263.A NZ ALA 214.A O no hydrogen 2.741 N/A ALA 264.A N GLY 260.A O no hydrogen 2.930 N/A ASP 265.A N VAL 261.A O no hydrogen 2.969 N/A LEU 266.A N PHE 262.A O no hydrogen 2.873 N/A ALA 267.A N LYS 263.A O no hydrogen 2.885 N/A GLN 268.A N ALA 264.A O no hydrogen 3.232 N/A VAL 269.A N ASP 265.A O no hydrogen 3.018 N/A VAL 270.A N LEU 266.A O no hydrogen 2.920 N/A ILE 271.A N ALA 267.A O no hydrogen 2.904 N/A GLU 272.A N GLN 268.A O no hydrogen 2.835 N/A THR 273.A N VAL 269.A O no hydrogen 2.979 N/A THR 273.A OG1 VAL 269.A O no hydrogen 2.904 N/A LEU 274.A N VAL 270.A O no hydrogen 2.900 N/A ARG 275.A N ILE 271.A O no hydrogen 2.863 N/A GLN 278.A N LEU 274.A O no hydrogen 2.815 N/A GLN 278.A NE2 LEU 200.A O no hydrogen 2.888 N/A GLN 278.A NE2 ASP 202.A O no hydrogen 2.834 N/A GLU 279.A N ARG 275.A O no hydrogen 3.028 N/A ARG 280.A N PRO 276.A O no hydrogen 3.057 N/A ARG 280.A NE ALA 66.A O no hydrogen 2.757 N/A ARG 280.A NH1 ALA 66.A O no hydrogen 2.786 N/A TYR 281.A N ILE 277.A O no hydrogen 2.799 N/A HIS 282.A N GLN 278.A O no hydrogen 3.050 N/A HIS 283.A N GLU 279.A O no hydrogen 3.320 N/A TRP 284.A N ARG 280.A O no hydrogen 2.931 N/A SER 286.A N TRP 284.A O no hydrogen 3.074 N/A GLU 288.A N SER 286.A OG no hydrogen 3.020 N/A ARG 291.A N GLU 287.A O no hydrogen 3.398 N/A VAL 292.A N GLU 288.A O no hydrogen 2.942 N/A LEU 293.A N LEU 289.A O no hydrogen 3.184 N/A ASP 294.A N ASP 290.A O no hydrogen 2.828 N/A GLU 295.A N ARG 291.A O no hydrogen 2.930 N/A GLY 296.A N VAL 292.A O no hydrogen 2.981 N/A ALA 297.A N LEU 293.A O no hydrogen 3.001 N/A GLU 298.A N ASP 294.A O no hydrogen 3.071 N/A LYS 299.A N GLU 295.A O no hydrogen 3.163 N/A LYS 299.A NZ TYR 35.A OH no hydrogen 3.397 N/A ALA 300.A N GLY 296.A O no hydrogen 2.886 N/A ASN 301.A N ALA 297.A O no hydrogen 2.733 N/A ASN 301.A ND2 GLU 81.A O no hydrogen 2.964 N/A ASN 301.A ND2 ALA 297.A O no hydrogen 2.925 N/A ARG 302.A N GLU 298.A O no hydrogen 3.180 N/A ARG 302.A NE GLU 298.A OE1 no hydrogen 3.184 N/A ARG 302.A NE GLU 298.A OE2 no hydrogen 2.628 N/A ARG 302.A NH2 GLU 298.A OE1 no hydrogen 2.665 N/A VAL 303.A N LYS 299.A O no hydrogen 3.194 N/A ALA 304.A N ALA 300.A O no hydrogen 2.764 N/A SER 305.A N ASN 301.A O no hydrogen 2.959 N/A SER 305.A OG.A ASN 301.A O no hydrogen 2.585 N/A SER 305.A OG.A ARG 302.A O no hydrogen 3.250 N/A SER 305.A OG.B ASN 301.A O no hydrogen 2.817 N/A ARG 308.A N SER 305.A O no hydrogen 3.062 N/A ARG 308.A NE GLU 306.A OE1 no hydrogen 2.909 N/A ARG 308.A NH2 GLU 306.A OE2 no hydrogen 2.689 N/A LYS 309.A N GLU 306.A O no hydrogen 3.078 N/A LYS 309.A NZ GLU 306.A OE2 no hydrogen 2.469 N/A GLN 311.A N ARG 308.A O no hydrogen 2.922 N/A ALA 312.A N LYS 309.A O no hydrogen 2.885 N/A LEU 314.A N GLU 310.A O no hydrogen 2.871 N/A