Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 1ime_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): MET 5.A N TRP 1.A O no hydrogen 3.003 N/A ASP 6.A N GLN 2.A O no hydrogen 2.820 N/A TYR 7.A N GLU 3.A O no hydrogen 3.040 N/A TYR 7.A OH SER 53.A O no hydrogen 3.151 N/A ALA 8.A N CYS 4.A O no hydrogen 2.783 N/A VAL 9.A N MET 5.A O no hydrogen 3.075 N/A THR 10.A N ASP 6.A O no hydrogen 3.202 N/A THR 10.A OG1 ASP 6.A O no hydrogen 2.951 N/A LEU 11.A N TYR 7.A O no hydrogen 2.779 N/A ALA 12.A N ALA 8.A O no hydrogen 2.907 N/A ARG 13.A N VAL 9.A O no hydrogen 3.125 N/A GLN 14.A N THR 10.A O no hydrogen 3.085 N/A ALA 15.A N LEU 11.A O no hydrogen 2.895 N/A GLY 16.A N ALA 12.A O no hydrogen 2.808 N/A GLU 17.A N ARG 13.A O no hydrogen 3.076 N/A VAL 18.A N GLN 14.A O no hydrogen 3.032 N/A VAL 19.A N ALA 15.A O no hydrogen 2.912 N/A CYS 20.A N GLY 16.A O no hydrogen 3.006 N/A GLU 21.A N GLU 17.A O no hydrogen 3.063 N/A GLU 21.A N VAL 18.A O no hydrogen 3.251 N/A ALA 22.A N VAL 18.A O no hydrogen 3.066 N/A ILE 23.A N VAL 19.A O no hydrogen 2.972 N/A LYS 24.A N GLU 21.A O no hydrogen 3.141 N/A ASN 25.A N ALA 22.A O no hydrogen 3.196 N/A MET 30.A N VAL 39.A O no hydrogen 2.875 N/A LYS 32.A N ASP 37.A O no hydrogen 2.858 N/A LYS 32.A NZ GLU 66.A OE2 no hydrogen 3.195 N/A LYS 32.A NZ GLU 67.A OE1 no hydrogen 2.791 N/A SER 33.A N ASP 37.A OD2 no hydrogen 3.095 N/A SER 33.A OG ASP 37.A OD2 no hydrogen 2.803 N/A VAL 36.A N SER 34.A OG no hydrogen 2.984 N/A ASP 37.A N SER 34.A O no hydrogen 3.192 N/A VAL 39.A N MET 30.A O no hydrogen 2.862 N/A THR 40.A N ASP 43.A OD1 no hydrogen 2.866 N/A THR 40.A OG1 ASP 43.A OD1 no hydrogen 2.721 N/A LYS 45.A N ALA 41.A O no hydrogen 2.890 N/A VAL 46.A N THR 42.A O no hydrogen 2.877 N/A GLU 47.A N ASP 43.A O no hydrogen 2.967 N/A LYS 48.A N GLN 44.A O no hydrogen 2.918 N/A MET 49.A N LYS 45.A O no hydrogen 3.007 N/A LEU 50.A N VAL 46.A O no hydrogen 2.939 N/A ILE 51.A N GLU 47.A O no hydrogen 3.056 N/A SER 52.A N LYS 48.A O no hydrogen 2.903 N/A SER 52.A OG LYS 48.A O no hydrogen 3.216 N/A SER 52.A OG MET 49.A O no hydrogen 3.020 N/A SER 53.A N MET 49.A O no hydrogen 3.103 N/A SER 53.A OG MET 49.A O no hydrogen 3.095 N/A ILE 54.A N LEU 50.A O no hydrogen 3.135 N/A LYS 55.A N ILE 51.A O no hydrogen 2.913 N/A GLU 56.A N SER 52.A O no hydrogen 2.945 N/A LYS 57.A N SER 53.A O no hydrogen 3.356 N/A TYR 58.A N ILE 54.A O no hydrogen 2.695 N/A TYR 58.A OH GLU 3.A OE1 no hydrogen 3.164 N/A HIS 61.A N TYR 58.A O no hydrogen 2.857 N/A SER 62.A N PRO 81.A O no hydrogen 2.852 N/A ILE 64.A N TRP 83.A O no hydrogen 2.818 N/A GLU 67.A N GLU 47.A OE1 no hydrogen 2.983 N/A SER 68.A N GLU 47.A OE2 no hydrogen 3.068 N/A SER 68.A OG GLU 47.A OE2 no hydrogen 2.712 N/A VAL 69.A N GLY 65.A O no hydrogen 3.176 N/A ALA 70.A N GLU 66.A O no hydrogen 2.995 N/A ALA 71.A N GLU 67.A O no hydrogen 2.737 N/A ALA 71.A N SER 68.A O no hydrogen 2.907 N/A GLY 72.A N VAL 69.A O no hydrogen 2.902 N/A GLU 73.A N SER 68.A O no hydrogen 2.952 N/A SER 75.A OG ASP 270.A O no hydrogen 3.381 N/A ASN 80.A N THR 78.A OG1 no hydrogen 3.241 N/A ASN 80.A ND2 SER 60.A O no hydrogen 2.888 N/A ASN 80.A ND2 SER 62.A OG no hydrogen 2.956 N/A THR 82.A N ALA 108.A O no hydrogen 2.878 N/A THR 82.A OG1 ASN 80.A O no hydrogen 2.822 N/A TRP 83.A N SER 62.A O no hydrogen 2.888 N/A TRP 83.A NE1 HIS 61.A ND1 no hydrogen 2.927 N/A ILE 84.A N GLY 106.A O no hydrogen 2.733 N/A ILE 85.A N ILE 64.A O no hydrogen 2.828 N/A ASP 86.A N SER 104.A O no hydrogen 3.134 N/A ILE 88.A N ASP 86.A OD1 no hydrogen 3.259 N/A ASP 89.A N ALA 102.A O no hydrogen 2.811 N/A THR 91.A OG1 ASP 43.A OD2 no hydrogen 2.829 N/A ASN 93.A ND2 PHE 100.A O no hydrogen 2.826 N/A ASN 93.A ND2 VAL 189.A O no hydrogen 2.987 N/A PHE 94.A N GLY 90.A O no hydrogen 2.809 N/A VAL 95.A N THR 91.A O no hydrogen 2.886 N/A HIS 96.A N THR 92.A O no hydrogen 3.326 N/A HIS 96.A N ASN 93.A O no hydrogen 3.069 N/A ARG 97.A N PHE 94.A O no hydrogen 2.994 N/A PHE 98.A N ASN 93.A O no hydrogen 2.829 N/A ALA 102.A N ASP 89.A O no hydrogen 3.009 N/A VAL 103.A N TYR 119.A O no hydrogen 2.970 N/A SER 104.A N ASP 86.A O no hydrogen 3.019 N/A ILE 105.A N VAL 117.A O no hydrogen 2.788 N/A GLY 106.A N ILE 84.A O no hydrogen 2.872 N/A PHE 107.A N PHE 115.A O no hydrogen 3.070 N/A ALA 108.A N THR 82.A O no hydrogen 2.911 N/A VAL 109.A N LYS 112.A O no hydrogen 3.101 N/A ASN 110.A N ASP 79.A O no hydrogen 3.032 N/A ASN 110.A ND2 ASP 79.A OD2 no hydrogen 3.238 N/A LYS 112.A N VAL 109.A O no hydrogen 3.105 N/A GLU 114.A N PHE 107.A O no hydrogen 2.864 N/A GLY 116.A N ALA 129.A O no hydrogen 3.130 N/A VAL 117.A N ILE 105.A O no hydrogen 2.810 N/A VAL 118.A N TYR 127.A O no hydrogen 3.082 N/A TYR 119.A N VAL 103.A O no hydrogen 2.898 N/A SER 120.A N LYS 125.A O no hydrogen 2.899 N/A SER 120.A OG GLU 123.A OE1 no hydrogen 2.794 N/A CYS 121.A N VAL 101.A O no hydrogen 3.116 N/A CYS 121.A SG GLY 16.A O no hydrogen 3.867 N/A CYS 121.A SG VAL 101.A O no hydrogen 3.752 N/A CYS 121.A SG TYR 119.A O no hydrogen 3.848 N/A GLY 124.A N SER 120.A O no hydrogen 2.880 N/A GLY 124.A N CYS 121.A O no hydrogen 3.098 N/A LYS 125.A N SER 120.A O no hydrogen 3.110 N/A LYS 125.A NZ GLU 123.A OE2 no hydrogen 3.093 N/A TYR 127.A N VAL 118.A O no hydrogen 2.935 N/A THR 128.A N PHE 136.A O no hydrogen 2.939 N/A ALA 129.A N GLY 116.A O no hydrogen 3.201 N/A ARG 130.A NE GLN 2.A OE1 no hydrogen 3.006 N/A LYS 131.A N GLU 114.A O no hydrogen 2.896 N/A GLY 132.A N GLU 226.A OE2 no hydrogen 2.949 N/A LYS 133.A N ARG 130.A O no hydrogen 2.797 N/A GLY 134.A N GLU 226.A OE1 no hydrogen 2.815 N/A PHE 136.A N THR 128.A O no hydrogen 2.908 N/A CYS 137.A N GLN 140.A O no hydrogen 2.910 N/A CYS 137.A SG MET 126.A O no hydrogen 3.983 N/A ASN 138.A N MET 126.A O no hydrogen 2.910 N/A GLN 140.A N CYS 137.A O no hydrogen 2.956 N/A LEU 142.A N ALA 135.A O no hydrogen 3.084 N/A VAL 144.A N ALA 227.A O no hydrogen 3.059 N/A SER 145.A OG ASP 205.A OD1 no hydrogen 2.605 N/A THR 151.A N ASP 149.A OD1 no hydrogen 3.219 N/A THR 151.A OG1 ASP 149.A OD1 no hydrogen 2.710 N/A LYS 152.A N ASP 149.A O no hydrogen 3.078 N/A LYS 152.A NZ ASP 149.A OD2 no hydrogen 3.401 N/A SER 153.A N ILE 150.A O no hydrogen 3.104 N/A SER 153.A OG ILE 150.A O no hydrogen 2.696 N/A LEU 154.A N ASP 205.A OD2 no hydrogen 2.974 N/A LEU 155.A N GLY 185.A O no hydrogen 3.169 N/A VAL 156.A N ALA 206.A O no hydrogen 2.933 N/A THR 157.A N ARG 187.A O no hydrogen 3.080 N/A THR 157.A OG1 TYR 208.A O no hydrogen 2.699 N/A SER 162.A OG THR 164.A OG1 no hydrogen 3.222 N/A ARG 163.A NH1 SER 162.A O no hydrogen 3.317 N/A THR 164.A N SER 162.A OG no hydrogen 3.120 N/A THR 164.A OG1 SER 162.A OG no hydrogen 3.222 N/A VAL 168.A N THR 164.A O no hydrogen 3.072 N/A ARG 169.A N PRO 165.A O no hydrogen 2.935 N/A MET 170.A N GLU 166.A O no hydrogen 2.960 N/A VAL 171.A N THR 167.A O no hydrogen 2.878 N/A LEU 172.A N VAL 168.A O no hydrogen 2.951 N/A SER 173.A N ARG 169.A O no hydrogen 2.874 N/A ASN 174.A N MET 170.A O no hydrogen 2.843 N/A ASN 174.A ND2 GLN 263.A O no hydrogen 2.895 N/A MET 175.A N VAL 171.A O no hydrogen 3.048 N/A GLU 176.A N LEU 172.A O no hydrogen 2.888 N/A LYS 177.A N SER 173.A O no hydrogen 3.167 N/A LYS 177.A NZ GLU 261.A O no hydrogen 3.408 N/A LYS 177.A NZ GLN 263.A OE1 no hydrogen 3.163 N/A LEU 178.A N ASN 174.A O no hydrogen 3.347 N/A PHE 179.A N MET 175.A O no hydrogen 2.933 N/A CYS 180.A N GLU 176.A O no hydrogen 2.980 N/A ILE 181.A N LEU 178.A O no hydrogen 3.181 N/A HIS 184.A N SER 153.A O no hydrogen 2.789 N/A ARG 187.A N LEU 155.A O no hydrogen 2.906 N/A ARG 187.A NH1 ILE 186.A O no hydrogen 3.190 N/A SER 188.A OG THR 157.A O no hydrogen 2.870 N/A VAL 189.A N ASN 195.A OD1 no hydrogen 3.362 N/A GLY 190.A N GLU 158.A OE2 no hydrogen 2.816 N/A THR 191.A OG1 ASP 89.A OD2 no hydrogen 2.655 N/A ALA 193.A N ASP 89.A OD2 no hydrogen 3.034 N/A VAL 194.A N THR 191.A OG1 no hydrogen 3.392 N/A ASN 195.A N THR 191.A O no hydrogen 3.003 N/A ASN 195.A ND2 GLU 158.A OE2 no hydrogen 2.671 N/A MET 196.A N ALA 192.A O no hydrogen 3.001 N/A CYS 197.A N ALA 193.A O no hydrogen 3.039 N/A CYS 197.A SG ALA 193.A O no hydrogen 3.261 N/A LEU 198.A N VAL 194.A O no hydrogen 2.992 N/A VAL 199.A N ASN 195.A O no hydrogen 3.287 N/A ALA 200.A N MET 196.A O no hydrogen 3.033 N/A THR 201.A N CYS 197.A O no hydrogen 3.090 N/A THR 201.A OG1 LEU 198.A O no hydrogen 2.849 N/A GLY 202.A N VAL 199.A O no hydrogen 2.962 N/A GLY 203.A N THR 201.A OG1 no hydrogen 3.253 N/A ALA 204.A N LEU 198.A O no hydrogen 3.224 N/A ASP 205.A N LEU 154.A O no hydrogen 2.835 N/A TYR 207.A N ALA 248.A O no hydrogen 2.838 N/A TYR 207.A OH GLU 209.A OE1 no hydrogen 2.756 N/A TYR 208.A N VAL 156.A O no hydrogen 3.365 N/A GLU 209.A N VAL 246.A O no hydrogen 3.023 N/A GLY 211.A N ARG 244.A O no hydrogen 2.672 N/A HIS 213.A N ASP 216.A OD2 no hydrogen 2.898 N/A HIS 213.A ND1 ASP 270.A OD1 no hydrogen 2.822 N/A CYS 214.A N ASP 270.A OD2 no hydrogen 2.836 N/A CYS 214.A SG ASP 270.A OD2 no hydrogen 3.652 N/A ASP 216.A N HIS 213.A O no hydrogen 2.974 N/A VAL 217.A N CYS 214.A O no hydrogen 3.423 N/A ALA 218.A N CYS 214.A O no hydrogen 3.036 N/A GLY 221.A N VAL 217.A O no hydrogen 3.061 N/A VAL 224.A N ALA 220.A O no hydrogen 3.070 N/A THR 225.A N GLY 221.A O no hydrogen 3.035 N/A THR 225.A OG1 GLY 221.A O no hydrogen 3.505 N/A THR 225.A OG1 ILE 222.A O no hydrogen 3.127 N/A GLU 226.A N ILE 222.A O no hydrogen 2.859 N/A ALA 227.A N ILE 223.A O no hydrogen 3.000 N/A ALA 227.A N VAL 224.A O no hydrogen 3.243 N/A GLY 228.A N THR 225.A O no hydrogen 2.959 N/A GLY 229.A N VAL 224.A O no hydrogen 2.879 N/A VAL 230.A N ALA 249.A O no hydrogen 2.941 N/A MET 232.A N ILE 247.A O no hydrogen 2.908 N/A ASP 233.A N GLY 237.A O no hydrogen 2.922 N/A THR 235.A N ASP 233.A OD1 no hydrogen 3.444 N/A GLY 236.A N ASP 233.A O no hydrogen 2.793 N/A GLY 237.A N THR 235.A OG1 no hydrogen 3.274 N/A MET 242.A N ASP 240.A OD1 no hydrogen 3.173 N/A SER 243.A N ASP 240.A O no hydrogen 3.005 N/A SER 243.A OG ASP 240.A O no hydrogen 2.822 N/A ARG 244.A NE ILE 212.A O no hydrogen 2.819 N/A ARG 244.A NH1 GLN 268.A O no hydrogen 2.834 N/A ARG 244.A NH2 GLY 211.A O no hydrogen 2.978 N/A ARG 245.A NE ASP 233.A OD1 no hydrogen 2.975 N/A ARG 245.A NH2 ASP 233.A OD2 no hydrogen 2.908 N/A VAL 246.A N GLU 209.A O no hydrogen 2.970 N/A ILE 247.A N MET 232.A O no hydrogen 2.820 N/A ALA 248.A N TYR 207.A O no hydrogen 2.883 N/A ALA 249.A N VAL 230.A O no hydrogen 2.949 N/A ASN 250.A N ASP 205.A O no hydrogen 2.900 N/A ASN 250.A ND2 SER 145.A O no hydrogen 3.476 N/A ASN 250.A ND2 SER 145.A OG no hydrogen 3.004 N/A ASN 250.A ND2 GLN 147.A O no hydrogen 2.901 N/A ASN 251.A ND2 GLN 147.A O no hydrogen 2.787 N/A ILE 253.A N ASN 251.A OD1 no hydrogen 2.970 N/A LEU 254.A N ASN 251.A OD1 no hydrogen 2.963 N/A ALA 255.A N ASN 251.A O no hydrogen 3.137 N/A GLU 256.A N ARG 252.A O no hydrogen 3.091 N/A ARG 257.A N ILE 253.A O no hydrogen 3.204 N/A ARG 257.A N LEU 254.A O no hydrogen 2.982 N/A ARG 257.A NE GLU 261.A OE2 no hydrogen 2.927 N/A ARG 257.A NH2 GLU 261.A OE2 no hydrogen 2.798 N/A ILE 258.A N LEU 254.A O no hydrogen 2.909 N/A ALA 259.A N ALA 255.A O no hydrogen 2.838 N/A LYS 260.A N GLU 256.A O no hydrogen 3.147 N/A LYS 260.A N ARG 257.A O no hydrogen 3.231 N/A GLU 261.A N ARG 257.A O no hydrogen 3.336 N/A GLU 261.A N ILE 258.A O no hydrogen 3.089 N/A ILE 262.A N ILE 258.A O no hydrogen 3.302 N/A GLN 263.A N ASN 174.A OD1 no hydrogen 2.960 N/A GLN 268.A NE2 ARG 269.A O no hydrogen 3.562 N/A GLN 268.A NE2 GLU 272.A O no hydrogen 2.945 N/A ARG 269.A N GLU 272.A OE2 no hydrogen 3.131 N/A ARG 269.A NE ASP 271.A OD1 no hydrogen 3.018 N/A ARG 269.A NH1 ASP 240.A OD2 no hydrogen 2.841 N/A ARG 269.A NH2 ASP 240.A OD1 no hydrogen 3.434 N/A ARG 269.A NH2 ASP 240.A OD2 no hydrogen 2.954 N/A ARG 269.A NH2 ASP 271.A OD2 no hydrogen 3.246 N/A ASP 270.A N MET 242.A O no hydrogen 3.026 N/A