Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 1iow_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LYS 4.A NZ MET 53.A O no hydrogen 3.381 N/A ILE 5.A N ASP 36.A O no hydrogen 3.066 N/A ALA 6.A N LYS 57.A O no hydrogen 3.019 N/A VAL 7.A N TYR 38.A O no hydrogen 2.812 N/A LEU 8.A N PHE 59.A O no hydrogen 3.153 N/A LEU 9.A N VAL 40.A O no hydrogen 2.950 N/A GLY 10.A N SER 19.A OG no hydrogen 3.139 N/A GLY 11.A N ASP 41.A OD1 no hydrogen 3.083 N/A SER 13.A OG HIS 63.A O no hydrogen 2.649 N/A GLU 15.A N SER 13.A OG no hydrogen 3.338 N/A ARG 16.A N SER 13.A O no hydrogen 3.242 N/A ARG 16.A NH1 GLY 11.A O no hydrogen 2.967 N/A ARG 16.A NH1 ASP 41.A OD2 no hydrogen 3.176 N/A SER 19.A N GLU 15.A O no hydrogen 3.088 N/A SER 19.A OG ALA 61.A O no hydrogen 2.636 N/A LEU 20.A N ARG 16.A O no hydrogen 3.085 N/A ASN 21.A N GLU 17.A O no hydrogen 3.387 N/A SER 22.A N VAL 18.A O no hydrogen 2.941 N/A SER 22.A OG VAL 18.A O no hydrogen 3.200 N/A SER 22.A OG HIS 63.A NE2 no hydrogen 2.822 N/A GLY 23.A N SER 19.A O no hydrogen 2.876 N/A ALA 24.A N LEU 20.A O no hydrogen 3.030 N/A ALA 25.A N ASN 21.A O no hydrogen 3.462 N/A VAL 26.A N SER 22.A O no hydrogen 3.041 N/A LEU 27.A N GLY 23.A O no hydrogen 2.871 N/A ALA 28.A N ALA 24.A O no hydrogen 3.246 N/A GLY 29.A N ALA 25.A O no hydrogen 2.992 N/A LEU 30.A N VAL 26.A O no hydrogen 2.838 N/A ARG 31.A N LEU 27.A O no hydrogen 3.049 N/A ARG 31.A NE ALA 37.A O no hydrogen 3.196 N/A ARG 31.A NH2 ALA 37.A O no hydrogen 2.828 N/A GLU 32.A N ALA 28.A O no hydrogen 2.770 N/A GLY 33.A N GLY 29.A O no hydrogen 3.158 N/A GLY 33.A N LEU 30.A O no hydrogen 3.152 N/A GLY 34.A N ARG 31.A O no hydrogen 2.949 N/A ILE 35.A N LEU 30.A O no hydrogen 2.908 N/A TYR 38.A N ILE 5.A O no hydrogen 2.940 N/A TYR 38.A OH ASP 36.A OD2 no hydrogen 2.852 N/A VAL 40.A N VAL 7.A O no hydrogen 2.939 N/A LYS 43.A N ASP 41.A OD1 no hydrogen 2.953 N/A GLU 44.A N ASP 41.A O no hydrogen 2.852 N/A VAL 45.A N ASP 41.A O no hydrogen 2.751 N/A THR 48.A N ASP 46.A OD1 no hydrogen 3.045 N/A THR 48.A OG1 ASP 46.A OD1 no hydrogen 3.173 N/A GLN 49.A N ASP 46.A O no hydrogen 3.003 N/A LEU 50.A N VAL 47.A O no hydrogen 3.109 N/A LYS 51.A NZ MET 79.A O no hydrogen 3.438 N/A MET 53.A N LEU 50.A O no hydrogen 3.346 N/A GLY 54.A N LYS 51.A O no hydrogen 3.120 N/A GLN 56.A N LYS 4.A O no hydrogen 2.698 N/A VAL 58.A N PRO 82.A O no hydrogen 2.966 N/A PHE 59.A N ALA 6.A O no hydrogen 2.858 N/A ILE 60.A N THR 84.A OG1 no hydrogen 2.846 N/A ALA 61.A N LEU 8.A O no hydrogen 2.966 N/A HIS 63.A ND1 SER 274.A O no hydrogen 2.766 N/A HIS 63.A NE2 SER 22.A OG no hydrogen 2.822 N/A GLY 64.A N GLU 68.A OE1 no hydrogen 2.709 N/A ARG 65.A NE ARG 147.A O no hydrogen 3.008 N/A ARG 65.A NH1 HIS 173.A O no hydrogen 3.216 N/A ARG 65.A NH2 ARG 147.A O no hydrogen 3.402 N/A ARG 65.A NH2 HIS 173.A O no hydrogen 2.757 N/A GLY 66.A N ASP 69.A OD2 no hydrogen 2.815 N/A GLY 67.A N GLY 64.A O no hydrogen 3.173 N/A GLU 68.A N GLY 64.A O no hydrogen 2.825 N/A THR 71.A N ASP 69.A OD1 no hydrogen 3.176 N/A THR 71.A OG1 ASP 69.A OD1 no hydrogen 2.766 N/A GLN 73.A NE2 GLY 67.A O no hydrogen 2.916 N/A GLY 74.A N GLY 70.A O no hydrogen 2.843 N/A MET 75.A N THR 71.A O no hydrogen 3.090 N/A LEU 76.A N LEU 72.A O no hydrogen 3.178 N/A GLU 77.A N GLN 73.A O no hydrogen 3.014 N/A GLU 77.A N GLY 74.A O no hydrogen 3.024 N/A LEU 78.A N GLY 74.A O no hydrogen 3.173 N/A MET 79.A N MET 75.A O no hydrogen 2.825 N/A GLY 80.A N LEU 76.A O no hydrogen 3.026 N/A LEU 81.A N LEU 76.A O no hydrogen 3.032 N/A TYR 83.A N ASP 306.A OXT no hydrogen 2.936 N/A TYR 83.A OH GLU 77.A OE2 no hydrogen 2.864 N/A THR 84.A N VAL 58.A O no hydrogen 3.145 N/A SER 86.A OG LYS 251.A O no hydrogen 3.425 N/A SER 91.A N GLY 87.A O no hydrogen 3.190 N/A SER 91.A OG SER 86.A O no hydrogen 3.387 N/A SER 91.A OG GLY 87.A O no hydrogen 2.802 N/A ALA 92.A N VAL 88.A O no hydrogen 3.009 N/A LEU 93.A N MET 89.A O no hydrogen 2.876 N/A SER 94.A N ALA 90.A O no hydrogen 2.855 N/A SER 94.A OG ALA 90.A O no hydrogen 3.007 N/A MET 95.A N SER 91.A O no hydrogen 3.269 N/A LYS 97.A N SER 146.A O no hydrogen 3.178 N/A LYS 97.A NZ GLU 148.A O no hydrogen 2.699 N/A LYS 97.A NZ GLU 270.A OE1 no hydrogen 3.170 N/A ARG 99.A N ASP 96.A OD1 no hydrogen 2.933 N/A ARG 99.A NH1 ASP 96.A OD2 no hydrogen 2.925 N/A ARG 99.A NH1 GLU 176.A OE1 no hydrogen 3.094 N/A SER 100.A N ASP 96.A O no hydrogen 2.895 N/A SER 100.A OG LEU 93.A O no hydrogen 2.838 N/A SER 100.A OG ASP 96.A O no hydrogen 2.895 N/A LYS 101.A N LYS 97.A O no hydrogen 3.211 N/A LYS 101.A NZ ALA 112.A O no hydrogen 3.150 N/A LEU 102.A N LEU 98.A O no hydrogen 3.192 N/A LEU 103.A N ARG 99.A O no hydrogen 3.239 N/A TRP 104.A N SER 100.A O no hydrogen 2.904 N/A GLN 105.A N LYS 101.A O no hydrogen 2.834 N/A GLY 106.A N LEU 102.A O no hydrogen 2.774 N/A ALA 107.A N LEU 103.A O no hydrogen 2.972 N/A ALA 107.A N TRP 104.A O no hydrogen 3.141 N/A GLY 108.A N GLN 105.A O no hydrogen 2.999 N/A LEU 109.A N TRP 104.A O no hydrogen 2.959 N/A VAL 115.A N ILE 179.A O no hydrogen 2.858 N/A LEU 117.A N VAL 177.A O no hydrogen 2.917 N/A THR 118.A N GLU 121.A OE2 no hydrogen 2.853 N/A THR 118.A OG1 GLU 121.A OE2 no hydrogen 2.830 N/A ARG 119.A N GLU 175.A O no hydrogen 2.861 N/A PHE 122.A N THR 118.A O no hydrogen 3.198 N/A GLU 123.A N ARG 119.A O no hydrogen 2.859 N/A LYS 124.A N ALA 120.A O no hydrogen 3.020 N/A LYS 124.A NZ GLU 123.A OE1 no hydrogen 3.165 N/A GLY 125.A N PHE 122.A O no hydrogen 3.284 N/A SER 127.A OG SER 127.A O no hydrogen 2.615 N/A LYS 129.A NZ ASP 128.A OD2 no hydrogen 3.070 N/A GLN 130.A N SER 127.A O no hydrogen 2.566 N/A GLN 130.A NE2 GLU 121.A OE1 no hydrogen 3.226 N/A ALA 132.A N ASP 128.A O no hydrogen 3.216 N/A GLU 133.A N LYS 129.A O no hydrogen 3.145 N/A GLU 133.A N GLN 130.A O no hydrogen 3.011 N/A ILE 134.A N GLN 130.A O no hydrogen 3.090 N/A SER 135.A N LEU 131.A O no hydrogen 2.699 N/A SER 135.A OG LEU 131.A O no hydrogen 2.760 N/A LEU 137.A N ILE 134.A O no hydrogen 3.291 N/A GLY 138.A N SER 135.A O no hydrogen 3.103 N/A VAL 141.A N VAL 157.A O no hydrogen 3.177 N/A ILE 142.A N GLU 180.A O no hydrogen 2.793 N/A VAL 143.A N SER 155.A O no hydrogen 3.035 N/A LYS 144.A N LEU 178.A O no hydrogen 3.050 N/A LYS 144.A NZ GLU 180.A OE2 no hydrogen 3.147 N/A SER 146.A N GLU 176.A O no hydrogen 3.084 N/A ARG 147.A N ASP 174.A OD2 no hydrogen 2.886 N/A ARG 147.A NH2 ASP 174.A OD1 no hydrogen 3.570 N/A GLY 149.A N GLU 148.A OE1 no hydrogen 3.418 N/A SER 150.A OG GLU 15.A OE1 no hydrogen 2.770 N/A SER 151.A OG TYR 210.A O no hydrogen 2.798 N/A VAL 152.A N GLY 149.A O no hydrogen 3.126 N/A SER 155.A N VAL 143.A O no hydrogen 3.157 N/A VAL 157.A N VAL 141.A O no hydrogen 3.057 N/A ALA 162.A N ALA 159.A O no hydrogen 3.018 N/A LEU 163.A N GLU 160.A O no hydrogen 3.138 N/A LEU 167.A N LEU 163.A O no hydrogen 3.016 N/A ARG 168.A N GLN 164.A O no hydrogen 2.987 N/A LEU 169.A N ASP 165.A O no hydrogen 3.184 N/A LEU 169.A N ALA 166.A O no hydrogen 3.231 N/A ALA 170.A N ALA 166.A O no hydrogen 3.115 N/A PHE 171.A N LEU 167.A O no hydrogen 2.975 N/A GLN 172.A N LEU 169.A O no hydrogen 3.207 N/A HIS 173.A N ALA 170.A O no hydrogen 2.987 N/A ASP 174.A N ALA 170.A O no hydrogen 3.352 N/A GLU 175.A N ASP 174.A OD1 no hydrogen 2.977 N/A VAL 177.A N LEU 117.A O no hydrogen 2.858 N/A LEU 178.A N LYS 144.A O no hydrogen 3.130 N/A ILE 179.A N VAL 115.A O no hydrogen 2.843 N/A GLU 180.A N ILE 142.A O no hydrogen 2.788 N/A LYS 181.A N PRO 113.A O no hydrogen 2.870 N/A SER 184.A N ASP 261.A OD1 no hydrogen 3.268 N/A SER 184.A OG GLY 185.A O no hydrogen 3.172 N/A GLY 185.A N LEU 260.A O no hydrogen 2.868 N/A PHE 188.A N VAL 258.A O no hydrogen 2.673 N/A THR 189.A N ILE 201.A O no hydrogen 3.118 N/A THR 189.A OG1 ILE 256.A O no hydrogen 3.354 N/A THR 189.A OG1 ASP 257.A OD1 no hydrogen 2.879 N/A VAL 190.A N ILE 256.A O no hydrogen 2.913 N/A ILE 192.A N GLY 254.A O no hydrogen 2.813 N/A LEU 193.A N GLU 196.A O no hydrogen 2.911 N/A GLY 194.A N GLY 252.A O no hydrogen 2.647 N/A GLU 196.A N LEU 193.A O no hydrogen 3.340 N/A LEU 198.A N ALA 191.A O no hydrogen 2.947 N/A SER 200.A OG GLU 234.A OE1 no hydrogen 2.619 N/A SER 200.A OG GLU 234.A OE2 no hydrogen 3.192 N/A ILE 201.A N THR 189.A O no hydrogen 3.187 N/A ARG 202.A N PHE 224.A O no hydrogen 2.919 N/A ARG 202.A NE ALA 227.A O no hydrogen 3.411 N/A ARG 202.A NH1 GLN 204.A OE1 no hydrogen 3.201 N/A ILE 203.A N GLU 187.A O no hydrogen 3.039 N/A GLN 204.A N GLN 222.A O no hydrogen 2.878 N/A ASP 211.A N PHE 209.A O no hydrogen 2.721 N/A ALA 214.A N ASP 211.A OD1 no hydrogen 2.917 N/A LYS 215.A N ASP 211.A O no hydrogen 2.929 N/A LYS 215.A N TYR 212.A O no hydrogen 3.198 N/A LYS 215.A NZ SER 151.A OG no hydrogen 2.914 N/A PHE 216.A N TYR 212.A O no hydrogen 3.063 N/A LEU 217.A N GLU 213.A O no hydrogen 2.760 N/A SER 218.A N GLU 213.A O no hydrogen 2.823 N/A THR 221.A OG1 ALA 214.A O no hydrogen 2.723 N/A GLN 222.A N GLN 204.A O no hydrogen 2.944 N/A PHE 224.A N ARG 202.A O no hydrogen 3.084 N/A CYS 225.A SG PRO 199.A O no hydrogen 3.845 N/A CYS 225.A SG SER 200.A O no hydrogen 3.487 N/A GLN 233.A N GLU 230.A O no hydrogen 2.758 N/A GLU 234.A N GLU 230.A O no hydrogen 2.883 N/A ALA 235.A N ALA 231.A O no hydrogen 2.694 N/A ASN 236.A N SER 232.A O no hydrogen 3.233 N/A LEU 237.A N GLN 233.A O no hydrogen 2.898 N/A GLN 238.A N GLU 234.A O no hydrogen 3.431 N/A ALA 239.A N ALA 235.A O no hydrogen 3.204 N/A LEU 240.A N ASN 236.A O no hydrogen 3.091 N/A VAL 241.A N LEU 237.A O no hydrogen 2.879 N/A LEU 242.A N GLN 238.A O no hydrogen 2.842 N/A LYS 243.A N ALA 239.A O no hydrogen 3.008 N/A ALA 244.A N LEU 240.A O no hydrogen 2.878 N/A TRP 245.A N VAL 241.A O no hydrogen 2.808 N/A THR 246.A N LEU 242.A O no hydrogen 2.971 N/A THR 246.A OG1 LEU 242.A O no hydrogen 3.497 N/A THR 246.A OG1 LYS 243.A O no hydrogen 3.457 N/A THR 247.A N LYS 243.A O no hydrogen 2.952 N/A THR 247.A OG1 LYS 243.A O no hydrogen 2.931 N/A LEU 248.A N ALA 244.A O no hydrogen 3.304 N/A GLY 249.A N TRP 245.A O no hydrogen 3.208 N/A GLY 249.A N THR 246.A O no hydrogen 3.111 N/A CYS 250.A N TRP 245.A O no hydrogen 3.434 N/A CYS 250.A SG SER 94.A OG no hydrogen 3.495 N/A LYS 251.A N SER 86.A OG no hydrogen 3.122 N/A LYS 251.A NZ ASP 306.A OD2 no hydrogen 3.340 N/A GLY 254.A N ILE 192.A O no hydrogen 3.022 N/A ARG 255.A N ASN 272.A O no hydrogen 3.135 N/A ARG 255.A NE THR 189.A OG1 no hydrogen 2.574 N/A ARG 255.A NE ASP 257.A OD1 no hydrogen 3.430 N/A ARG 255.A NH2 ASP 257.A OD1 no hydrogen 2.799 N/A ARG 255.A NH2 ASP 257.A OD2 no hydrogen 3.369 N/A ILE 256.A N VAL 190.A O no hydrogen 2.973 N/A ASP 257.A N GLU 270.A O no hydrogen 2.955 N/A VAL 258.A N PHE 188.A O no hydrogen 2.831 N/A MET 259.A N TYR 267.A O no hydrogen 3.103 N/A LEU 260.A N PRO 186.A O no hydrogen 3.044 N/A ASP 261.A N GLN 265.A O no hydrogen 3.189 N/A GLY 264.A N ASP 261.A O no hydrogen 2.664 N/A GLN 265.A N ASP 263.A OD1 no hydrogen 2.948 N/A TYR 267.A N MET 259.A O no hydrogen 2.922 N/A TYR 267.A OH ASP 263.A OD2 no hydrogen 2.853 N/A LEU 268.A N PRO 110.A O no hydrogen 2.870 N/A LEU 269.A N ASP 257.A O no hydrogen 2.869 N/A ASN 272.A N ARG 255.A O no hydrogen 2.873 N/A ASN 272.A ND2 ARG 255.A O no hydrogen 3.575 N/A ASN 272.A ND2 ASP 257.A OD2 no hydrogen 3.339 N/A ASN 272.A ND2 GLU 270.A OE2 no hydrogen 3.101 N/A SER 274.A N GLU 68.A OE2 no hydrogen 3.001 N/A SER 274.A OG ILE 60.A O no hydrogen 3.268 N/A SER 274.A OG LEU 62.A O no hydrogen 2.867 N/A MET 277.A N SER 22.A OG no hydrogen 3.022 N/A THR 278.A OG1 SER 281.A OG no hydrogen 2.947 N/A HIS 280.A N THR 278.A OG1 no hydrogen 3.146 N/A SER 281.A N THR 278.A O no hydrogen 3.221 N/A SER 281.A OG THR 278.A OG1 no hydrogen 2.947 N/A ALA 286.A N LEU 282.A O no hydrogen 3.091 N/A ALA 287.A N VAL 283.A O no hydrogen 3.148 N/A ARG 288.A N PRO 284.A O no hydrogen 3.100 N/A GLN 289.A N MET 285.A O no hydrogen 3.308 N/A ALA 290.A N ALA 286.A O no hydrogen 2.992 N/A GLY 291.A N ARG 288.A O no hydrogen 2.839 N/A MET 292.A N ALA 287.A O no hydrogen 2.989 N/A SER 293.A N GLN 296.A OE1 no hydrogen 2.910 N/A SER 295.A OG GLY 29.A O no hydrogen 2.988 N/A GLN 296.A N SER 293.A OG no hydrogen 3.108 N/A LEU 297.A N SER 293.A O no hydrogen 3.105 N/A VAL 298.A N PHE 294.A O no hydrogen 3.166 N/A VAL 299.A N SER 295.A O no hydrogen 2.864 N/A ARG 300.A N GLN 296.A O no hydrogen 2.875 N/A ARG 300.A NH1 GLU 303.A OE1 no hydrogen 2.837 N/A ILE 301.A N LEU 297.A O no hydrogen 2.884 N/A LEU 302.A N VAL 298.A O no hydrogen 3.097 N/A GLU 303.A N VAL 299.A O no hydrogen 3.060 N/A LEU 304.A N ARG 300.A O no hydrogen 3.144 N/A LEU 304.A N ILE 301.A O no hydrogen 3.179 N/A ALA 305.A N LEU 302.A O no hydrogen 3.028 N/A ASP 306.A N TYR 83.A O no hydrogen 3.126 N/A