Finding intermodel H-bonds
Finding intramodel H-bonds
Constraints relaxed by 0.4 angstroms and 20 degrees
Models used:
	#0 1iug_A.cif

H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist):
ASP 1.A N      GLY 304.A O    no hydrogen  3.455  N/A
TRP 2.A N      GLY 304.A O    no hydrogen  3.027  N/A
LEU 4.A N      VAL 306.A O    no hydrogen  2.917  N/A
THR 5.A OG1    PRO 8.A O      no hydrogen  3.022  N/A
HIS 12.A N     MET 186.A O    no hydrogen  3.283  N/A
LYS 14.A NZ    GLU 243.A OE2  no hydrogen  2.862  N/A
ALA 15.A N     HIS 12.A O     no hydrogen  2.879  N/A
GLU 17.A N     PRO 13.A O     no hydrogen  3.317  N/A
ALA 18.A N     LYS 14.A O     no hydrogen  3.184  N/A
LEU 19.A N     ALA 15.A O     no hydrogen  3.062  N/A
ALA 20.A N     GLU 17.A O     no hydrogen  3.104  N/A
ARG 21.A N     ALA 18.A O     no hydrogen  3.254  N/A
GLN 23.A NE2   LEU 24.A O     no hydrogen  3.277  N/A
GLN 23.A NE2   ASN 232.A OD1  no hydrogen  3.181  N/A
ARG 27.A N     HIS 25.A ND1   no hydrogen  3.102  N/A
THR 28.A N     HIS 25.A O     no hydrogen  3.200  N/A
ARG 32.A N     THR 28.A O     no hydrogen  3.148  N/A
GLU 33.A N     GLU 29.A O     no hydrogen  3.177  N/A
VAL 34.A N     ALA 30.A O     no hydrogen  3.199  N/A
PHE 35.A N     ALA 31.A O     no hydrogen  2.857  N/A
LEU 36.A N     ARG 32.A O     no hydrogen  2.776  N/A
LYS 37.A N     GLU 33.A O     no hydrogen  2.763  N/A
ALA 38.A N     VAL 34.A O     no hydrogen  2.843  N/A
ARG 39.A N     PHE 35.A O     no hydrogen  2.905  N/A
ARG 39.A NE    VAL 52.A O     no hydrogen  2.513  N/A
ARG 39.A NH2   GLU 51.A OE1   no hydrogen  2.774  N/A
ARG 39.A NH2   VAL 52.A O     no hydrogen  3.072  N/A
GLY 40.A N     LEU 36.A O     no hydrogen  3.001  N/A
LEU 41.A N     LYS 37.A O     no hydrogen  2.990  N/A
LEU 42.A N     ALA 38.A O     no hydrogen  2.934  N/A
ARG 43.A N     ARG 39.A O     no hydrogen  3.058  N/A
ARG 43.A NE    THR 48.A O     no hydrogen  2.859  N/A
GLU 44.A N     GLY 40.A O     no hydrogen  3.228  N/A
ALA 45.A N     LEU 41.A O     no hydrogen  2.890  N/A
PHE 46.A N     LEU 42.A O     no hydrogen  2.876  N/A
ARG 47.A N     GLU 44.A O     no hydrogen  3.141  N/A
THR 48.A N     ARG 43.A O     no hydrogen  3.439  N/A
THR 48.A OG1   GLU 171.A OE1  no hydrogen  3.403  N/A
THR 48.A OG1   GLU 171.A OE2  no hydrogen  2.865  N/A
GLU 49.A N     GLU 171.A OE1  no hydrogen  2.799  N/A
GLY 50.A N     THR 48.A OG1   no hydrogen  2.874  N/A
GLU 51.A N     LEU 196.A O    no hydrogen  2.903  N/A
LEU 53.A N     VAL 194.A O    no hydrogen  2.771  N/A
ILE 54.A N     GLN 220.A OE1  no hydrogen  2.841  N/A
LEU 55.A N     GLY 192.A O    no hydrogen  2.812  N/A
GLY 57.A N     GLY 190.A O    no hydrogen  2.915  N/A
LEU 61.A N     SER 58.A O     no hydrogen  3.101  N/A
MET 63.A N     GLY 59.A O     no hydrogen  3.139  N/A
GLU 64.A N     THR 60.A O     no hydrogen  3.016  N/A
ALA 65.A N     LEU 61.A O     no hydrogen  2.988  N/A
LEU 66.A N     ALA 62.A O     no hydrogen  3.058  N/A
VAL 67.A N     MET 63.A O     no hydrogen  3.187  N/A
LYS 68.A N     GLU 64.A O     no hydrogen  2.940  N/A
LYS 68.A NZ    GLU 95.A OE1   no hydrogen  3.162  N/A
ASN 69.A N     ALA 65.A O     no hydrogen  3.072  N/A
ASN 69.A ND2   ALA 65.A O     no hydrogen  2.757  N/A
ASN 69.A ND2   LEU 211.A O    no hydrogen  3.023  N/A
LEU 70.A N     VAL 67.A O     no hydrogen  3.478  N/A
PHE 71.A N     VAL 67.A O     no hydrogen  3.134  N/A
ALA 72.A N     GLU 75.A OE1   no hydrogen  2.908  N/A
GLY 74.A N     GLY 97.A O     no hydrogen  2.806  N/A
GLU 75.A N     ALA 72.A O     no hydrogen  3.253  N/A
VAL 77.A N     VAL 99.A O     no hydrogen  3.018  N/A
LEU 78.A N     GLY 123.A O    no hydrogen  2.879  N/A
VAL 79.A N     GLU 101.A O    no hydrogen  2.937  N/A
VAL 81.A N     LEU 103.A O    no hydrogen  2.866  N/A
TYR 82.A N     SER 86.A OG    no hydrogen  2.899  N/A
TYR 82.A OH    VAL 127.A O    no hydrogen  2.749  N/A
LYS 84.A N     SER 132.A OG   no hydrogen  2.944  N/A
LYS 84.A NZ    GLN 311.A OE1  no hydrogen  2.367  N/A
PHE 85.A N     GLU 130.A OE2  no hydrogen  3.066  N/A
SER 86.A N     GLU 130.A OE1  no hydrogen  2.933  N/A
SER 86.A OG    GLY 83.A O     no hydrogen  3.245  N/A
SER 86.A OG    GLU 130.A OE1  no hydrogen  3.045  N/A
GLU 87.A N     GLY 83.A O     no hydrogen  2.883  N/A
ARG 88.A N     LYS 84.A O     no hydrogen  2.805  N/A
ARG 88.A NE    THR 60.A OG1   no hydrogen  2.861  N/A
ARG 88.A NH2   THR 60.A OG1   no hydrogen  2.663  N/A
PHE 89.A N     PHE 85.A O     no hydrogen  2.950  N/A
TYR 90.A N     SER 86.A O     no hydrogen  3.167  N/A
GLU 91.A N     GLU 87.A O     no hydrogen  3.380  N/A
ILE 92.A N     ARG 88.A O     no hydrogen  3.289  N/A
ALA 93.A N     PHE 89.A O     no hydrogen  2.968  N/A
LEU 94.A N     TYR 90.A O     no hydrogen  3.016  N/A
GLU 95.A N     GLU 91.A O     no hydrogen  3.012  N/A
ALA 96.A N     ILE 92.A O     no hydrogen  2.967  N/A
GLY 97.A N     LEU 94.A O     no hydrogen  2.837  N/A
LEU 98.A N     ALA 93.A O     no hydrogen  3.162  N/A
VAL 99.A N     GLU 75.A O     no hydrogen  3.062  N/A
GLU 101.A N    VAL 77.A O     no hydrogen  3.092  N/A
LEU 103.A N    VAL 79.A O     no hydrogen  3.429  N/A
TYR 105.A N    VAL 81.A O     no hydrogen  2.838  N/A
TYR 105.A OH   ASP 115.A OD2  no hydrogen  2.659  N/A
ASP 109.A N    PRO 106.A O    no hydrogen  2.905  N/A
ASP 115.A N    ARG 112.A O    no hydrogen  2.900  N/A
LYS 118.A N    VAL 116.A O    no hydrogen  2.769  N/A
LYS 118.A NZ   GLU 101.A OE1  no hydrogen  3.505  N/A
LYS 118.A NZ   ASP 115.A O    no hydrogen  2.878  N/A
GLY 120.A N    ASN 150.A OD1  no hydrogen  3.055  N/A
TYR 121.A N    ASN 150.A OD1  no hydrogen  3.031  N/A
TYR 121.A OH   GLU 101.A OE2  no hydrogen  2.580  N/A
ALA 122.A N    ARG 76.A O     no hydrogen  2.738  N/A
GLY 123.A N    ARG 76.A O     no hydrogen  3.344  N/A
LEU 124.A N    LEU 154.A O    no hydrogen  2.902  N/A
LEU 125.A N    LEU 78.A O     no hydrogen  3.127  N/A
LEU 126.A N    GLY 156.A O    no hydrogen  2.944  N/A
VAL 127.A N    TYR 82.A OH    no hydrogen  3.112  N/A
HIS 128.A N    ASP 158.A O    no hydrogen  2.921  N/A
SER 129.A OG   THR 161.A O    no hydrogen  3.524  N/A
SER 129.A OG   THR 161.A OG1  no hydrogen  2.840  N/A
SER 129.A OG   SER 279.A OG   no hydrogen  2.613  N/A
GLU 130.A N    ALA 135.A O    no hydrogen  2.861  N/A
THR 131.A OG1  SER 129.A O    no hydrogen  3.540  N/A
THR 131.A OG1  THR 161.A OG1  no hydrogen  2.741  N/A
SER 132.A OG   GLU 130.A OE2  no hydrogen  2.750  N/A
THR 133.A N    GLU 130.A O    no hydrogen  3.017  N/A
THR 133.A OG1  GLU 130.A O    no hydrogen  3.386  N/A
GLY 134.A N    GLU 130.A O    no hydrogen  2.758  N/A
ALA 135.A N    THR 133.A OG1  no hydrogen  3.238  N/A
LEU 136.A N    ARG 277.A O    no hydrogen  3.186  N/A
ALA 137.A N    HIS 128.A O    no hydrogen  2.925  N/A
LEU 142.A N    ASP 138.A O    no hydrogen  2.981  N/A
ALA 143.A N    LEU 139.A O    no hydrogen  2.869  N/A
ARG 144.A N    PRO 140.A O    no hydrogen  3.155  N/A
ALA 145.A N    ALA 141.A O    no hydrogen  3.337  N/A
PHE 146.A N    LEU 142.A O    no hydrogen  3.193  N/A
LYS 147.A N    ALA 143.A O    no hydrogen  2.980  N/A
LYS 147.A NZ   ASP 176.A OD2  no hydrogen  3.299  N/A
GLU 148.A N    ARG 144.A O    no hydrogen  2.964  N/A
ASN 150.A N    PHE 146.A O    no hydrogen  2.853  N/A
ASN 150.A ND2  LYS 118.A O    no hydrogen  2.532  N/A
ASN 150.A ND2  PHE 146.A O    no hydrogen  3.058  N/A
GLY 153.A N    ASN 150.A O    no hydrogen  2.859  N/A
LEU 154.A N    ALA 122.A O    no hydrogen  2.963  N/A
VAL 155.A N    ASP 176.A OD2  no hydrogen  2.833  N/A
GLY 156.A N    LEU 124.A O    no hydrogen  2.907  N/A
ALA 157.A N    ALA 177.A O    no hydrogen  2.745  N/A
ASP 158.A N    LEU 126.A O    no hydrogen  2.799  N/A
MET 159.A N    ALA 179.A O    no hydrogen  2.780  N/A
VAL 160.A N    ASP 158.A OD1  no hydrogen  2.941  N/A
THR 161.A OG1  SER 129.A OG   no hydrogen  2.840  N/A
THR 161.A OG1  THR 131.A OG1  no hydrogen  2.741  N/A
SER 162.A N    MET 159.A O    no hydrogen  3.293  N/A
LEU 163.A N    MET 159.A O    no hydrogen  3.091  N/A
VAL 165.A N    SER 162.A O    no hydrogen  3.064  N/A
GLY 166.A N    SER 162.A O    no hydrogen  2.905  N/A
LEU 170.A N    ARG 47.A O     no hydrogen  3.327  N/A
GLU 171.A N    GLU 171.A OE2  no hydrogen  2.763  N/A
MET 173.A N    LEU 170.A O    no hydrogen  2.907  N/A
GLY 174.A N    GLU 171.A O    no hydrogen  3.004  N/A
VAL 175.A N    LEU 170.A O    no hydrogen  2.900  N/A
ASP 176.A N    VAL 155.A O    no hydrogen  2.925  N/A
ALA 177.A N    VAL 155.A O    no hydrogen  3.303  N/A
ALA 178.A N    ALA 195.A O    no hydrogen  2.954  N/A
ALA 179.A N    ALA 157.A O    no hydrogen  2.871  N/A
SER 180.A N    PHE 193.A O    no hydrogen  3.012  N/A
SER 180.A OG   MET 159.A O    no hydrogen  3.379  N/A
SER 182.A N    LEU 191.A O    no hydrogen  3.126  N/A
SER 182.A OG   PRO 188.A O    no hydrogen  2.707  N/A
SER 182.A OG   LEU 191.A O    no hydrogen  3.437  N/A
GLN 183.A N    GLN 183.A OE1  no hydrogen  2.725  N/A
CYS 187.A N    SER 182.A O    no hydrogen  3.193  N/A
CYS 187.A SG   LEU 185.A O    no hydrogen  3.598  N/A
LEU 191.A N    SER 182.A OG   no hydrogen  3.186  N/A
GLY 192.A N    LEU 55.A O     no hydrogen  2.861  N/A
PHE 193.A N    SER 180.A O    no hydrogen  2.771  N/A
VAL 194.A N    LEU 53.A O     no hydrogen  3.054  N/A
ALA 195.A N    ALA 178.A O    no hydrogen  2.835  N/A
LEU 196.A N    GLU 51.A O     no hydrogen  2.780  N/A
SER 197.A N    ASP 176.A O    no hydrogen  2.946  N/A
SER 197.A OG   ASP 176.A O    no hydrogen  2.873  N/A
ARG 199.A NH1  GLY 153.A O    no hydrogen  3.138  N/A
ARG 199.A NH2  GLY 153.A O    no hydrogen  3.253  N/A
ALA 200.A N    SER 197.A OG   no hydrogen  3.287  N/A
LEU 201.A N    SER 197.A O    no hydrogen  2.953  N/A
GLU 202.A N    PRO 198.A O    no hydrogen  3.399  N/A
ARG 203.A N    ALA 200.A O    no hydrogen  3.080  N/A
ARG 203.A NH1  GLU 152.A O    no hydrogen  3.325  N/A
ARG 203.A NH2  GLU 152.A O    no hydrogen  3.141  N/A
LYS 205.A N    ASN 69.A O     no hydrogen  2.729  N/A
ARG 207.A N    ASN 69.A OD1   no hydrogen  3.484  N/A
ARG 207.A NH1  PHE 71.A O     no hydrogen  3.101  N/A
TYR 210.A OH   THR 56.A O     no hydrogen  2.792  N/A
ASP 212.A N    TYR 209.A O    no hydrogen  3.325  N/A
LEU 213.A N    ASN 69.A OD1   no hydrogen  2.961  N/A
ALA 214.A N    ASP 212.A OD1  no hydrogen  2.849  N/A
ARG 215.A N    ASP 212.A OD1  no hydrogen  3.350  N/A
LEU 217.A N    LEU 213.A O    no hydrogen  2.850  N/A
LYS 218.A N    ALA 214.A O    no hydrogen  3.085  N/A
ALA 219.A N    ARG 215.A O    no hydrogen  3.120  N/A
GLN 220.A N    GLU 216.A O    no hydrogen  2.571  N/A
GLN 220.A NE2  ILE 54.A O     no hydrogen  2.828  N/A
GLN 220.A NE2  GLU 216.A OE1  no hydrogen  2.928  N/A
LYS 221.A N    LEU 217.A O    no hydrogen  3.002  N/A
GLU 222.A N    ALA 219.A O    no hydrogen  3.112  N/A
GLY 223.A N    GLN 220.A O    no hydrogen  3.065  N/A
GLU 224.A N    ALA 219.A O    no hydrogen  2.987  N/A
SER 225.A OG   TRP 227.A O    no hydrogen  2.531  N/A
ALA 226.A N    GLU 216.A OE1  no hydrogen  2.981  N/A
TRP 227.A NE1  TYR 210.A O    no hydrogen  3.222  N/A
ALA 230.A N    THR 56.A OG1   no hydrogen  3.129  N/A
ILE 231.A N    PRO 229.A O    no hydrogen  2.673  N/A
ASN 232.A ND2  GLN 23.A OE1   no hydrogen  3.225  N/A
VAL 234.A N    ALA 230.A O    no hydrogen  3.118  N/A
LEU 235.A N    ILE 231.A O    no hydrogen  3.070  N/A
ALA 236.A N    ASN 232.A O    no hydrogen  3.312  N/A
VAL 237.A N    LEU 233.A O    no hydrogen  2.903  N/A
ALA 238.A N    VAL 234.A O    no hydrogen  2.942  N/A
ALA 239.A N    LEU 235.A O    no hydrogen  2.966  N/A
VAL 240.A N    ALA 236.A O    no hydrogen  3.113  N/A
LEU 241.A N    VAL 237.A O    no hydrogen  3.024  N/A
GLU 242.A N    ALA 238.A O    no hydrogen  2.946  N/A
GLU 243.A N    VAL 240.A O    no hydrogen  3.101  N/A
VAL 244.A N    VAL 240.A O    no hydrogen  2.938  N/A
LEU 245.A N    LEU 241.A O    no hydrogen  2.997  N/A
ARG 247.A N    VAL 244.A O    no hydrogen  2.939  N/A
LEU 248.A N    LEU 245.A O    no hydrogen  3.311  N/A
GLU 250.A N    GLU 250.A OE1  no hydrogen  2.679  N/A
HIS 251.A N    ARG 247.A O    no hydrogen  2.981  N/A
HIS 251.A NE2  LEU 164.A O    no hydrogen  2.852  N/A
LEU 252.A N    LEU 248.A O    no hydrogen  2.832  N/A
ALA 253.A N    GLU 249.A O    no hydrogen  3.052  N/A
LEU 254.A N    GLU 250.A O    no hydrogen  2.995  N/A
LYS 255.A N    HIS 251.A O    no hydrogen  3.058  N/A
ALA 256.A N    LEU 252.A O    no hydrogen  2.981  N/A
TRP 257.A N    ALA 253.A O    no hydrogen  2.949  N/A
GLN 258.A N    LEU 254.A O    no hydrogen  2.821  N/A
GLN 258.A NE2  TYR 327.A O    no hydrogen  2.930  N/A
GLN 258.A NE2  ASP 328.A O    no hydrogen  3.092  N/A
ASN 259.A N    LYS 255.A O    no hydrogen  3.138  N/A
ASN 259.A ND2  VAL 282.A O    no hydrogen  3.227  N/A
ALA 260.A N    ALA 256.A O    no hydrogen  3.108  N/A
LEU 261.A N    TRP 257.A O    no hydrogen  2.961  N/A
LEU 262.A N    GLN 258.A O    no hydrogen  3.386  N/A
TYR 263.A N    ASN 259.A O    no hydrogen  3.155  N/A
GLY 264.A N    ALA 260.A O    no hydrogen  2.903  N/A
VAL 265.A N    LEU 261.A O    no hydrogen  3.227  N/A
GLY 266.A N    LEU 262.A O    no hydrogen  3.126  N/A
GLU 267.A N    TYR 263.A O    no hydrogen  2.951  N/A
GLU 268.A N    GLY 264.A O    no hydrogen  3.169  N/A
GLY 269.A N    VAL 265.A O    no hydrogen  3.204  N/A
GLY 269.A N    GLY 266.A O    no hydrogen  3.091  N/A
GLY 270.A N    GLU 267.A O    no hydrogen  3.026  N/A
LEU 271.A N    GLY 266.A O    no hydrogen  2.922  N/A
VAL 274.A N    ALA 284.A O    no hydrogen  3.248  N/A
LYS 276.A NZ   ASP 109.A OD1  no hydrogen  2.955  N/A
SER 279.A N    GLY 134.A O    no hydrogen  3.085  N/A
SER 279.A OG   SER 129.A OG   no hydrogen  2.613  N/A
ALA 281.A N    SER 279.A OG   no hydrogen  3.338  N/A
ALA 283.A N    LEU 321.A O    no hydrogen  2.739  N/A
ALA 284.A N    TYR 263.A OH   no hydrogen  2.951  N/A
PHE 285.A N    PHE 319.A O    no hydrogen  3.068  N/A
TYR 286.A N    ARG 272.A O    no hydrogen  2.894  N/A
LEU 287.A N    LYS 317.A O    no hydrogen  2.850  N/A
VAL 291.A N    PRO 288.A O    no hydrogen  3.408  N/A
ARG 295.A N    PRO 292.A O    no hydrogen  3.122  N/A
LYS 297.A N    TYR 293.A O    no hydrogen  2.810  N/A
GLU 298.A N    ALA 294.A O    no hydrogen  2.918  N/A
ALA 299.A N    ARG 295.A O    no hydrogen  2.990  N/A
PHE 300.A N    VAL 296.A O    no hydrogen  3.107  N/A
ALA 301.A N    LYS 297.A O    no hydrogen  3.065  N/A
GLN 302.A N    GLU 298.A O    no hydrogen  3.016  N/A
ARG 303.A N    PHE 300.A O    no hydrogen  2.906  N/A
ARG 303.A NH1  GLU 345.A OE2  no hydrogen  3.358  N/A
ARG 303.A NH2  GLU 345.A OE2  no hydrogen  3.143  N/A
GLY 304.A N    ALA 301.A O    no hydrogen  2.830  N/A
ALA 305.A N    PHE 300.A O    no hydrogen  3.056  N/A
VAL 306.A N    TRP 2.A O      no hydrogen  2.909  N/A
ALA 308.A N    ARG 320.A O    no hydrogen  3.296  N/A
LEU 314.A N    GLN 311.A O    no hydrogen  3.110  N/A
LYS 315.A N    GLY 312.A O    no hydrogen  3.016  N/A
LYS 317.A N    LEU 314.A O    no hydrogen  2.897  N/A
PHE 319.A N    PHE 285.A O    no hydrogen  3.050  N/A
ARG 320.A N    ALA 308.A O    no hydrogen  2.814  N/A
ARG 320.A NE   GLY 309.A O    no hydrogen  3.117  N/A
ARG 320.A NH1  THR 131.A O    no hydrogen  2.869  N/A
ARG 320.A NH2  GLY 309.A O    no hydrogen  2.570  N/A
LEU 321.A N    ALA 283.A O    no hydrogen  2.986  N/A
SER 322.A N    LEU 4.A O      no hydrogen  2.831  N/A
SER 322.A OG   ALA 281.A O    no hydrogen  2.598  N/A
MET 324.A N    SER 322.A OG   no hydrogen  3.243  N/A
ALA 326.A N    ARG 10.A O     no hydrogen  3.021  N/A
TYR 327.A N    GLY 325.A O    no hydrogen  2.824  N/A
TYR 327.A OH   LEU 3.A O      no hydrogen  2.713  N/A
ASP 328.A N    GLU 331.A OE2  no hydrogen  2.935  N/A
GLU 331.A N    ASP 328.A OD2  no hydrogen  2.863  N/A
ALA 332.A N    ASP 328.A O    no hydrogen  3.202  N/A
LEU 333.A N    ARG 329.A O    no hydrogen  3.266  N/A
GLY 334.A N    TYR 330.A O    no hydrogen  3.117  N/A
VAL 335.A N    GLU 331.A O    no hydrogen  2.993  N/A
ALA 336.A N    ALA 332.A O    no hydrogen  2.906  N/A
GLY 337.A N    LEU 333.A O    no hydrogen  3.141  N/A
MET 338.A N    GLY 334.A O    no hydrogen  3.072  N/A
PHE 339.A N    VAL 335.A O    no hydrogen  2.807  N/A
ARG 340.A N    ALA 336.A O    no hydrogen  2.941  N/A
ARG 340.A NE   GLU 268.A OE2  no hydrogen  2.852  N/A
GLU 341.A N    GLY 337.A O    no hydrogen  3.018  N/A
VAL 342.A N    MET 338.A O    no hydrogen  3.045  N/A
LEU 343.A N    PHE 339.A O    no hydrogen  3.041  N/A
GLU 344.A N    ARG 340.A O    no hydrogen  3.012  N/A
GLU 345.A N    GLU 341.A O    no hydrogen  3.195  N/A
ILE 346.A N    VAL 342.A O    no hydrogen  3.063  N/A
LEU 347.A N    LEU 343.A O    no hydrogen  3.196  N/A