Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 1izd_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ALA 1.A N GLY 94.A O no hydrogen 3.083 N/A GLY 4.A N PHE 167.A O no hydrogen 3.033 N/A VAL 6.A N TYR 165.A O no hydrogen 3.038 N/A THR 8.A N GLY 163.A O no hydrogen 3.010 N/A THR 8.A OG1 ILE 18.A O no hydrogen 3.507 N/A THR 8.A OG1 THR 19.A OG1 no hydrogen 2.872 N/A ASN 9.A N ILE 18.A O no hydrogen 3.085 N/A THR 11.A N GLU 16.A O no hydrogen 2.932 N/A THR 11.A OG1 GLU 16.A O no hydrogen 3.354 N/A ASP 14.A N THR 11.A O no hydrogen 2.877 N/A GLU 15.A N SER 12.A O no hydrogen 3.173 N/A GLU 16.A N THR 11.A OG1 no hydrogen 3.233 N/A TYR 17.A OH LYS 158.A O no hydrogen 2.808 N/A ILE 18.A N ASN 9.A O no hydrogen 2.855 N/A THR 19.A N LEU 30.A O no hydrogen 2.841 N/A THR 19.A OG1 THR 8.A OG1 no hydrogen 2.872 N/A VAL 21.A N LEU 28.A O no hydrogen 2.970 N/A THR 22.A N THR 91.A O no hydrogen 3.152 N/A VAL 23.A N ASP 26.A O no hydrogen 2.765 N/A GLY 24.A N LYS 89.A O no hydrogen 2.744 N/A ASP 26.A N VAL 23.A O no hydrogen 2.966 N/A LEU 28.A N VAL 21.A O no hydrogen 2.965 N/A GLY 29.A N ASP 119.A OD2 no hydrogen 3.374 N/A LEU 30.A N THR 19.A O no hydrogen 2.839 N/A ASP 31.A N GLY 120.A O no hydrogen 2.851 N/A ASP 33.A N LEU 122.A O no hydrogen 2.990 N/A THR 34.A N THR 215.A OG1 no hydrogen 2.947 N/A THR 34.A OG1 ALA 213.A O no hydrogen 2.876 N/A GLY 35.A N ASP 33.A OD1 no hydrogen 2.747 N/A SER 36.A N ASP 33.A O no hydrogen 3.202 N/A ASP 38.A N SER 36.A OG no hydrogen 3.170 N/A TRP 40.A N LEU 121.A O no hydrogen 3.018 N/A VAL 41.A N GLU 103.A O no hydrogen 2.918 N/A PHE 42.A N ASP 119.A O no hydrogen 2.919 N/A SER 43.A N THR 46.A OG1 no hydrogen 2.877 N/A SER 43.A OG SER 104.A OG no hydrogen 2.610 N/A SER 43.A OG ALA 105.A O no hydrogen 3.376 N/A SER 44.A N TYR 57.A O no hydrogen 2.828 N/A GLN 45.A N SER 43.A OG no hydrogen 2.975 N/A GLN 45.A NE2 ASP 84.A OD1 no hydrogen 2.515 N/A GLN 45.A NE2 ASP 84.A OD2 no hydrogen 3.278 N/A GLN 45.A NE2 SER 104.A OG no hydrogen 2.667 N/A THR 46.A N SER 43.A O no hydrogen 3.044 N/A THR 46.A OG1 SER 43.A O no hydrogen 3.254 N/A THR 46.A OG1 ALA 105.A O no hydrogen 2.624 N/A GLU 50.A N PRO 47.A O no hydrogen 2.704 N/A ARG 51.A N PRO 47.A O no hydrogen 2.982 N/A ARG 51.A NE THR 46.A O no hydrogen 2.778 N/A ARG 51.A NH1 SER 44.A O no hydrogen 3.227 N/A HIS 54.A N ARG 51.A O no hydrogen 2.892 N/A HIS 54.A NE2 ASP 115.A O no hydrogen 3.024 N/A TYR 57.A N PHE 42.A O no hydrogen 2.929 N/A TYR 57.A OH ASP 88.A OD2 no hydrogen 2.642 N/A THR 58.A N ASP 26.A OD1 no hydrogen 2.819 N/A SER 62.A OG ASP 88.A OD1 no hydrogen 2.646 N/A SER 62.A OG ASP 88.A OD2 no hydrogen 3.557 N/A ALA 63.A N GLY 60.A O no hydrogen 2.950 N/A GLN 64.A N LYS 87.A O no hydrogen 2.939 N/A LYS 65.A NZ ASP 84.A OD2 no hydrogen 3.370 N/A ILE 66.A N VAL 85.A O no hydrogen 2.868 N/A ALA 69.A N ILE 66.A O no hydrogen 3.147 N/A THR 70.A N GLN 133.A O no hydrogen 2.819 N/A TRP 71.A N GLY 83.A O no hydrogen 3.199 N/A TRP 71.A NE1 SER 104.A O no hydrogen 3.162 N/A ILE 73.A N ALA 81.A O no hydrogen 2.896 N/A TYR 75.A N SER 79.A O no hydrogen 2.731 N/A GLY 78.A N TYR 75.A O no hydrogen 3.013 N/A SER 79.A N ASP 77.A OD1 no hydrogen 2.722 N/A SER 79.A OG ASP 77.A OD1 no hydrogen 3.113 N/A SER 79.A OG ASP 77.A OD2 no hydrogen 3.350 N/A SER 80.A OG ILE 73.A O no hydrogen 2.981 N/A ALA 81.A N ILE 73.A O no hydrogen 3.126 N/A SER 82.A N LYS 107.A O no hydrogen 3.202 N/A GLY 83.A N TRP 71.A O no hydrogen 3.101 N/A ASP 84.A N SER 104.A O no hydrogen 3.070 N/A TYR 86.A N VAL 102.A O no hydrogen 2.996 N/A TYR 86.A OH GLN 45.A OE1 no hydrogen 3.121 N/A LYS 87.A N GLN 64.A O no hydrogen 2.795 N/A LYS 87.A NZ SER 99.A O no hydrogen 2.882 N/A ASP 88.A N GLN 100.A O no hydrogen 2.884 N/A LYS 89.A N ASP 88.A OD1 no hydrogen 2.728 N/A LYS 89.A NZ ASP 98.A OD1 no hydrogen 2.600 N/A VAL 90.A N TYR 97.A O no hydrogen 2.917 N/A THR 91.A N THR 22.A O no hydrogen 2.915 N/A VAL 92.A N VAL 95.A O no hydrogen 2.748 N/A VAL 95.A N VAL 92.A O no hydrogen 3.007 N/A TYR 97.A N VAL 90.A O no hydrogen 3.021 N/A GLN 100.A N ASP 88.A O no hydrogen 2.827 N/A VAL 102.A N TYR 86.A O no hydrogen 2.584 N/A GLU 103.A N LEU 39.A O no hydrogen 2.906 N/A SER 104.A N ASP 84.A O no hydrogen 2.833 N/A SER 104.A OG SER 43.A OG no hydrogen 2.610 N/A ALA 105.A N VAL 41.A O no hydrogen 3.057 N/A GLU 106.A N SER 82.A O no hydrogen 2.740 N/A LYS 107.A N SER 82.A O no hydrogen 3.279 N/A VAL 108.A N GLU 50.A OE1 no hydrogen 3.076 N/A SER 109.A N SER 80.A O no hydrogen 3.064 N/A SER 109.A OG GLU 111.A OE1 no hydrogen 3.216 N/A SER 110.A OG GLU 111.A OE1 no hydrogen 3.174 N/A GLU 111.A N GLU 111.A OE1 no hydrogen 2.779 N/A THR 113.A N SER 109.A O no hydrogen 3.133 N/A THR 113.A OG1 GLU 50.A O no hydrogen 2.737 N/A GLN 114.A N SER 110.A O no hydrogen 2.878 N/A ASP 115.A N GLU 111.A O no hydrogen 3.113 N/A ASP 115.A N PHE 112.A O no hydrogen 3.211 N/A THR 116.A N GLN 114.A O no hydrogen 2.938 N/A ASN 118.A N ASP 115.A O no hydrogen 3.016 N/A ASN 118.A ND2 GLU 16.A OE1 no hydrogen 3.231 N/A ASP 119.A N GLY 29.A O no hydrogen 2.857 N/A GLY 120.A N ASN 118.A OD1 no hydrogen 2.974 N/A LEU 121.A N TRP 40.A O no hydrogen 2.868 N/A LEU 122.A N ASP 31.A O no hydrogen 3.016 N/A GLY 123.A N ASP 38.A O no hydrogen 2.740 N/A LEU 124.A N ASP 33.A O no hydrogen 2.760 N/A ALA 125.A N SER 36.A O no hydrogen 2.863 N/A PHE 126.A N GLY 189.A O no hydrogen 2.997 N/A SER 127.A OG ASP 142.A OD2 no hydrogen 3.182 N/A ILE 129.A N PHE 126.A O no hydrogen 3.105 N/A ASN 130.A N SER 127.A O no hydrogen 2.995 N/A ASN 130.A ND2 ALA 37.A O no hydrogen 2.920 N/A ASN 130.A ND2 GLU 103.A OE2 no hydrogen 3.169 N/A THR 131.A N ASP 38.A OD1 no hydrogen 3.021 N/A THR 131.A OG1 ASP 38.A OD2 no hydrogen 2.703 N/A VAL 132.A N ASN 130.A OD1 no hydrogen 3.021 N/A GLN 133.A N THR 70.A O no hydrogen 2.847 N/A GLN 133.A NE2 VAL 132.A O no hydrogen 2.838 N/A GLN 137.A N ASN 130.A OD1 no hydrogen 2.819 N/A THR 139.A N SER 127.A OG no hydrogen 2.982 N/A ASP 142.A N THR 139.A OG1 no hydrogen 3.061 N/A ASN 143.A N THR 139.A O no hydrogen 3.029 N/A VAL 144.A N PHE 140.A O no hydrogen 2.988 N/A LYS 145.A N PHE 141.A O no hydrogen 2.845 N/A SER 147.A N VAL 144.A O no hydrogen 2.888 N/A SER 147.A OG VAL 144.A O no hydrogen 2.666 N/A LEU 148.A N LYS 145.A O no hydrogen 3.155 N/A SER 149.A N ALA 2.A O no hydrogen 2.945 N/A ILE 152.A N GLU 150.A O no hydrogen 2.754 N/A PHE 153.A N PHE 310.A O no hydrogen 3.070 N/A ALA 154.A N ASP 166.A O no hydrogen 2.679 N/A VAL 155.A N VAL 308.A O no hydrogen 2.809 N/A ALA 156.A N VAL 164.A O no hydrogen 2.876 N/A LYS 158.A NZ GLN 322.A OE1 no hydrogen 2.923 N/A HIS 159.A ND1 ASP 14.A OD2 no hydrogen 2.526 N/A ASN 160.A N ASP 14.A OD1 no hydrogen 2.967 N/A GLY 163.A N THR 8.A O no hydrogen 2.800 N/A VAL 164.A N ALA 156.A O no hydrogen 3.123 N/A TYR 165.A N VAL 6.A O no hydrogen 3.039 N/A ASP 166.A N ALA 154.A O no hydrogen 2.784 N/A PHE 167.A N GLY 4.A O no hydrogen 2.751 N/A GLY 168.A N ILE 152.A O no hydrogen 2.734 N/A ASP 171.A N TYR 307.A OH no hydrogen 2.892 N/A SER 173.A N ASP 171.A OD1 no hydrogen 2.943 N/A SER 173.A OG ASP 171.A OD1 no hydrogen 2.698 N/A SER 173.A OG ASP 171.A OD2 no hydrogen 3.352 N/A LYS 174.A N ASP 171.A O no hydrogen 2.881 N/A THR 176.A N ALA 321.A O no hydrogen 2.855 N/A THR 176.A OG1 ALA 321.A O no hydrogen 3.542 N/A THR 180.A N PHE 319.A O no hydrogen 2.912 N/A THR 182.A N LEU 317.A O no hydrogen 2.909 N/A VAL 184.A N PRO 315.A O no hydrogen 3.010 N/A ASP 185.A N GLY 192.A O no hydrogen 2.740 N/A SER 187.A N ASP 185.A OD1 no hydrogen 2.994 N/A SER 187.A OG ASP 185.A OD1 no hydrogen 2.733 N/A SER 187.A OG ASP 185.A OD2 no hydrogen 3.490 N/A SER 187.A OG GLN 188.A OE1 no hydrogen 3.093 N/A GLY 189.A N ASN 186.A O no hydrogen 2.840 N/A TRP 191.A NE1 LEU 124.A O no hydrogen 2.914 N/A GLY 192.A N ASP 185.A O no hydrogen 3.190 N/A PHE 193.A N GLY 211.A O no hydrogen 2.894 N/A THR 194.A OG1 THR 210.A OG1 no hydrogen 2.727 N/A ALA 195.A N ILE 209.A O no hydrogen 2.751 N/A ASP 196.A N THR 260.A O no hydrogen 2.746 N/A GLY 197.A N THR 260.A O no hydrogen 3.440 N/A TYR 198.A N SER 205.A O no hydrogen 3.395 N/A SER 199.A N SER 258.A O no hydrogen 2.891 N/A SER 199.A OG GLY 201.A O no hydrogen 2.913 N/A ILE 200.A N ASP 203.A O no hydrogen 2.934 N/A GLY 201.A N ASP 256.A O no hydrogen 2.822 N/A ASP 203.A N ILE 200.A O no hydrogen 2.930 N/A SER 205.A N TYR 198.A O no hydrogen 2.750 N/A ASP 207.A N SER 205.A OG no hydrogen 3.177 N/A ILE 209.A N ALA 195.A O no hydrogen 2.992 N/A THR 210.A OG1 THR 194.A OG1 no hydrogen 2.727 N/A GLY 211.A N PHE 193.A O no hydrogen 3.037 N/A ILE 212.A N SER 296.A O no hydrogen 2.969 N/A ALA 213.A N TRP 191.A O no hydrogen 3.098 N/A ASP 214.A N PHE 298.A O no hydrogen 3.111 N/A THR 215.A N THR 34.A OG1 no hydrogen 2.888 N/A THR 215.A OG1 PHE 32.A O no hydrogen 2.718 N/A THR 215.A OG1 TYR 165.A OH no hydrogen 3.389 N/A GLY 216.A N ASP 214.A OD1 no hydrogen 2.749 N/A THR 217.A N ASP 214.A O no hydrogen 3.233 N/A THR 217.A OG1 ASP 214.A OD2 no hydrogen 2.738 N/A THR 218.A OG1 GLU 15.A O no hydrogen 2.714 N/A LEU 220.A N GLY 286.A O no hydrogen 3.082 N/A LEU 221.A N ILE 297.A O no hydrogen 2.966 N/A LEU 222.A N GLN 288.A O no hydrogen 2.986 N/A VAL 227.A N ASP 223.A O no hydrogen 2.932 N/A ASP 228.A N ASP 224.A O no hydrogen 2.764 N/A ALA 229.A N SER 225.A O no hydrogen 3.130 N/A TYR 230.A N ILE 226.A O no hydrogen 2.852 N/A TYR 230.A OH PRO 255.A O no hydrogen 2.633 N/A TYR 231.A N VAL 227.A O no hydrogen 3.102 N/A TYR 231.A OH ILE 287.A O no hydrogen 2.545 N/A GLU 232.A N ALA 229.A O no hydrogen 3.303 N/A GLN 233.A N TYR 230.A O no hydrogen 2.947 N/A VAL 234.A N TYR 231.A O no hydrogen 3.065 N/A ALA 237.A N VAL 234.A O no hydrogen 3.157 N/A SER 238.A N VAL 247.A O no hydrogen 2.955 N/A ASP 240.A N GLY 245.A O no hydrogen 2.755 N/A SER 242.A OG ASP 240.A OD2 no hydrogen 2.536 N/A GLN 243.A N ASP 240.A O no hydrogen 3.080 N/A GLN 243.A N ASP 240.A OD2 no hydrogen 2.754 N/A GLY 244.A N ASP 240.A O no hydrogen 2.820 N/A GLY 244.A N SER 241.A O no hydrogen 3.335 N/A GLY 245.A N ASP 240.A O no hydrogen 3.313 N/A TYR 246.A N GLN 288.A OE1 no hydrogen 2.854 N/A TYR 246.A OH ASP 228.A OD2 no hydrogen 2.718 N/A VAL 247.A N SER 238.A O no hydrogen 2.836 N/A PHE 248.A N THR 283.A O no hydrogen 2.981 N/A SER 250.A N GLY 281.A O no hydrogen 2.942 N/A SER 250.A OG THR 283.A OG1 no hydrogen 2.911 N/A ALA 252.A N PRO 249.A O no hydrogen 2.745 N/A PHE 257.A N VAL 268.A O no hydrogen 3.027 N/A SER 258.A N SER 199.A O no hydrogen 3.038 N/A VAL 259.A N ALA 266.A O no hydrogen 3.031 N/A THR 260.A N GLY 197.A O no hydrogen 2.662 N/A ILE 261.A N TYR 264.A O no hydrogen 2.877 N/A GLY 262.A N ASP 196.A OD1 no hydrogen 2.837 N/A TYR 264.A N ILE 261.A O no hydrogen 2.925 N/A ALA 266.A N VAL 259.A O no hydrogen 2.897 N/A VAL 268.A N PHE 257.A O no hydrogen 2.693 N/A GLY 270.A N ASP 256.A OD2 no hydrogen 2.754 N/A TYR 272.A N PRO 269.A O no hydrogen 2.870 N/A ILE 273.A N GLY 270.A O no hydrogen 2.890 N/A SER 274.A N GLU 271.A O no hydrogen 3.326 N/A SER 274.A OG GLU 271.A O no hydrogen 2.662 N/A SER 274.A OG SER 274.A O no hydrogen 2.565 N/A ALA 276.A N PHE 284.A O no hydrogen 3.352 N/A VAL 278.A N GLN 282.A O no hydrogen 2.989 N/A GLY 279.A N ASP 277.A OD1 no hydrogen 2.617 N/A GLN 282.A N GLY 279.A O no hydrogen 2.986 N/A THR 283.A N PHE 248.A O no hydrogen 2.709 N/A THR 283.A OG1 SER 250.A OG no hydrogen 2.911 N/A PHE 284.A N ALA 276.A O no hydrogen 2.709 N/A GLY 285.A N TYR 246.A O no hydrogen 2.985 N/A GLY 286.A N ILE 273.A O no hydrogen 2.699 N/A GLN 288.A N LEU 220.A O no hydrogen 3.059 N/A GLN 288.A NE2 TYR 246.A O no hydrogen 3.174 N/A GLN 288.A NE2 GLY 285.A O no hydrogen 2.900 N/A SER 289.A OG ASP 224.A OD1 no hydrogen 2.541 N/A ASN 290.A N LEU 222.A O no hydrogen 2.861 N/A ASN 290.A ND2 ASP 223.A OD2 no hydrogen 2.874 N/A ASN 290.A ND2 SER 296.A OG no hydrogen 3.131 N/A SER 291.A N SER 289.A OG no hydrogen 2.920 N/A ILE 293.A N ASN 290.A O no hydrogen 2.866 N/A SER 296.A N THR 210.A O no hydrogen 3.374 N/A ILE 297.A N LEU 221.A O no hydrogen 2.908 N/A PHE 298.A N ILE 212.A O no hydrogen 2.830 N/A ASP 300.A N THR 217.A O no hydrogen 2.742 N/A VAL 301.A N THR 218.A O no hydrogen 2.977 N/A PHE 302.A N GLY 299.A O no hydrogen 3.005 N/A LEU 303.A N GLY 299.A O no hydrogen 2.906 N/A LYS 304.A N ASP 300.A O no hydrogen 2.926 N/A LYS 304.A NZ ASP 14.A OD2 no hydrogen 2.946 N/A SER 305.A N PHE 302.A O no hydrogen 3.367 N/A SER 305.A OG THR 267.A O no hydrogen 3.011 N/A SER 305.A OG PHE 302.A O no hydrogen 3.079 N/A SER 305.A OG GLN 306.A OE1 no hydrogen 3.053 N/A GLN 306.A N LEU 303.A O no hydrogen 2.880 N/A GLN 306.A NE2 TYR 264.A OH no hydrogen 2.549 N/A TYR 307.A N ALA 320.A O no hydrogen 2.906 N/A TYR 307.A OH ASP 166.A OD2 no hydrogen 2.700 N/A VAL 308.A N VAL 155.A O no hydrogen 2.938 N/A VAL 309.A N GLY 318.A O no hydrogen 2.786 N/A PHE 310.A N PHE 153.A O no hydrogen 2.736 N/A ASP 311.A N ARG 316.A O no hydrogen 2.965 N/A ALA 312.A N PRO 151.A O no hydrogen 2.956 N/A SER 313.A N ASP 311.A OD1 no hydrogen 2.787 N/A SER 313.A OG ASP 311.A OD1 no hydrogen 2.628 N/A SER 313.A OG ASP 311.A OD2 no hydrogen 3.225 N/A ARG 316.A N ASP 311.A O no hydrogen 2.975 N/A ARG 316.A NH1 ASP 311.A OD2 no hydrogen 2.897 N/A LEU 317.A N THR 182.A O no hydrogen 2.870 N/A GLY 318.A N VAL 309.A O no hydrogen 2.789 N/A PHE 319.A N THR 180.A O no hydrogen 2.779 N/A ALA 320.A N TYR 307.A O no hydrogen 3.136 N/A GLN 322.A NE2 LEU 157.A O no hydrogen 2.706 N/A GLN 322.A NE2 GLN 306.A O no hydrogen 2.860 N/A ALA 323.A N LYS 174.A O no hydrogen 2.977 N/A