Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 1k7h_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASP 3.A N GLU 1.A O no hydrogen 2.883 N/A TYR 6.A N ASP 3.A OD1 no hydrogen 3.122 N/A TRP 7.A N ASP 3.A O no hydrogen 3.078 N/A TRP 7.A NE1 GLU 2.A O no hydrogen 3.107 N/A ASN 8.A N LYS 4.A O no hydrogen 2.979 N/A LYS 9.A N ALA 5.A O no hydrogen 2.959 N/A ASP 10.A N TYR 6.A O no hydrogen 2.940 N/A ALA 11.A N TRP 7.A O no hydrogen 2.764 N/A GLN 12.A N ASN 8.A O no hydrogen 2.735 N/A ASP 13.A N LYS 9.A O no hydrogen 2.918 N/A ALA 14.A N ASP 10.A O no hydrogen 3.228 N/A LEU 15.A N ALA 11.A O no hydrogen 2.794 N/A ASP 16.A N GLN 12.A O no hydrogen 2.806 N/A LYS 17.A N ASP 13.A O no hydrogen 2.849 N/A LYS 17.A NZ GLU 67.A O no hydrogen 3.367 N/A GLN 18.A N ALA 14.A O no hydrogen 2.964 N/A LEU 19.A N LEU 15.A O no hydrogen 2.914 N/A GLY 20.A N ASP 16.A O no hydrogen 3.243 N/A GLY 20.A N LYS 17.A O no hydrogen 3.227 N/A ILE 21.A N GLN 18.A O no hydrogen 3.327 N/A ARG 24.A NE GLU 347.A OE1 no hydrogen 3.118 N/A ARG 24.A NH2 GLU 347.A OE2 no hydrogen 2.956 N/A LYS 26.A NZ GLU 347.A OE1 no hydrogen 2.786 N/A GLN 27.A NE2 ALA 466.A O no hydrogen 3.099 N/A ALA 28.A N ALA 465.A O no hydrogen 2.688 N/A LYS 29.A N GLU 348.A O no hydrogen 2.949 N/A ASN 30.A N GLU 348.A O no hydrogen 3.082 N/A ASN 30.A ND2 THR 349.A OG1 no hydrogen 3.400 N/A VAL 31.A N PHE 305.A O no hydrogen 3.008 N/A ILE 32.A N ILE 350.A O no hydrogen 2.833 N/A PHE 33.A N LEU 307.A O no hydrogen 2.802 N/A PHE 34.A N LEU 352.A O no hydrogen 2.670 N/A LEU 35.A N VAL 309.A O no hydrogen 2.973 N/A GLY 36.A N THR 354.A O no hydrogen 2.885 N/A ASP 37.A N GLY 311.A O no hydrogen 3.076 N/A GLY 38.A N ASP 356.A OD1 no hydrogen 2.911 N/A MET 39.A N GLY 36.A O no hydrogen 3.047 N/A SER 40.A N GLY 38.A O no hydrogen 2.988 N/A SER 40.A OG SER 42.A OG no hydrogen 2.587 N/A SER 40.A OG THR 43.A OG1 no hydrogen 2.900 N/A SER 42.A OG SER 40.A OG no hydrogen 2.587 N/A SER 42.A OG LEU 361.A O no hydrogen 2.869 N/A THR 43.A N SER 40.A OG no hydrogen 2.993 N/A THR 43.A OG1 SER 40.A OG no hydrogen 2.900 N/A THR 43.A OG1 HIS 318.A NE2 no hydrogen 2.897 N/A VAL 44.A N SER 40.A O no hydrogen 3.106 N/A THR 45.A N LEU 41.A O no hydrogen 2.914 N/A THR 45.A OG1 LEU 41.A O no hydrogen 3.364 N/A ALA 46.A N SER 42.A O no hydrogen 2.939 N/A ALA 47.A N THR 43.A O no hydrogen 2.790 N/A ARG 48.A N VAL 44.A O no hydrogen 2.791 N/A ARG 48.A NE GLU 66.A OE1 no hydrogen 3.131 N/A ARG 48.A NH2 GLU 66.A OE2 no hydrogen 2.822 N/A ILE 49.A N THR 45.A O no hydrogen 3.137 N/A TYR 50.A N ALA 46.A O no hydrogen 2.816 N/A LYS 51.A N ALA 47.A O no hydrogen 2.760 N/A LYS 51.A NZ LYS 62.A O no hydrogen 2.868 N/A LYS 51.A NZ GLU 334.A OE2 no hydrogen 2.438 N/A GLY 52.A N ARG 48.A O no hydrogen 3.019 N/A GLY 53.A N ILE 49.A O no hydrogen 2.967 N/A GLY 53.A N TYR 50.A O no hydrogen 3.059 N/A LEU 54.A N LYS 51.A O no hydrogen 2.868 N/A THR 55.A N LYS 51.A O no hydrogen 2.959 N/A THR 55.A OG1 LYS 51.A O no hydrogen 3.448 N/A THR 55.A OG1 GLY 52.A O no hydrogen 3.484 N/A THR 55.A OG1 GLU 61.A OE1 no hydrogen 2.603 N/A GLY 56.A N GLY 52.A O no hydrogen 2.658 N/A LYS 57.A N THR 55.A OG1 no hydrogen 3.359 N/A PHE 58.A N GLY 52.A O no hydrogen 3.087 N/A ARG 60.A N LYS 57.A O no hydrogen 3.077 N/A ARG 60.A NH1 TYR 6.A OH no hydrogen 2.901 N/A ARG 60.A NH1 ASP 10.A OD1 no hydrogen 3.304 N/A ARG 60.A NH2 ASP 10.A OD1 no hydrogen 2.971 N/A ARG 60.A NH2 ASP 10.A OD2 no hydrogen 3.264 N/A GLU 61.A N PHE 58.A O no hydrogen 3.029 N/A LYS 62.A N GLU 61.A OE2 no hydrogen 2.786 N/A ILE 63.A N GLU 66.A OE1 no hydrogen 3.117 N/A SER 64.A N GLU 334.A OE2 no hydrogen 2.833 N/A SER 64.A OG GLU 334.A O no hydrogen 2.958 N/A GLU 66.A N ILE 63.A O no hydrogen 2.764 N/A GLU 67.A N SER 64.A O no hydrogen 3.210 N/A PHE 68.A N TRP 65.A O no hydrogen 3.005 N/A ALA 72.A N ILE 439.A O no hydrogen 2.771 N/A LEU 73.A N GLY 451.A O no hydrogen 2.978 N/A SER 74.A N VAL 437.A O no hydrogen 2.863 N/A LYS 75.A N TYR 453.A O no hydrogen 2.875 N/A LYS 75.A NZ GLU 454.A OE2 no hydrogen 3.557 N/A TYR 77.A OH GLU 454.A OE1 no hydrogen 3.024 N/A TYR 77.A OH GLU 454.A OE2 no hydrogen 2.371 N/A ASN 78.A N LYS 81.A O no hydrogen 3.035 N/A ASN 78.A ND2 THR 84.A OG1 no hydrogen 2.973 N/A ASN 78.A ND2 GLN 101.A OE1 no hydrogen 2.783 N/A THR 79.A N THR 99.A O no hydrogen 3.197 N/A THR 79.A OG1 ASN 100.A OD1 no hydrogen 2.380 N/A ASP 80.A N ASN 78.A OD1 no hydrogen 3.023 N/A LYS 81.A N ASN 78.A OD1 no hydrogen 2.706 N/A THR 84.A OG1 ASP 85.A O no hydrogen 2.882 N/A ASP 85.A N GLN 101.A OE1 no hydrogen 2.791 N/A SER 86.A OG ASP 37.A OD1 no hydrogen 3.364 N/A SER 86.A OG ASP 37.A OD2 no hydrogen 3.242 N/A SER 86.A OG ASP 356.A OD2 no hydrogen 2.940 N/A SER 86.A OG HIS 357.A NE2 no hydrogen 3.084 N/A ALA 88.A N ASP 85.A OD1 no hydrogen 2.924 N/A SER 89.A OG ASP 85.A O no hydrogen 2.889 N/A SER 89.A OG SER 86.A O no hydrogen 3.218 N/A ALA 90.A N SER 86.A O no hydrogen 3.120 N/A THR 91.A N ALA 87.A O no hydrogen 3.027 N/A THR 91.A OG1 ALA 87.A O no hydrogen 3.034 N/A THR 91.A OG1 VAL 103.A O no hydrogen 3.193 N/A ALA 92.A N ALA 88.A O no hydrogen 3.075 N/A TYR 93.A N SER 89.A O no hydrogen 2.886 N/A LEU 94.A N ALA 90.A O no hydrogen 3.024 N/A THR 95.A N THR 91.A O no hydrogen 2.936 N/A THR 95.A OG1 THR 91.A O no hydrogen 2.381 N/A THR 95.A OG1 THR 125.A OG1 no hydrogen 3.140 N/A GLY 96.A N ALA 92.A O no hydrogen 2.931 N/A LYS 98.A NZ LYS 75.A O no hydrogen 2.862 N/A LYS 98.A NZ TYR 77.A O no hydrogen 2.635 N/A LYS 98.A NZ GLU 454.A OE1 no hydrogen 2.836 N/A THR 99.A OG1 LEU 106.A O no hydrogen 2.875 N/A ASN 100.A N THR 99.A OG1 no hydrogen 2.658 N/A ASN 100.A ND2 ALA 108.A O no hydrogen 2.810 N/A ASN 100.A ND2 THR 110.A O no hydrogen 2.722 N/A GLN 101.A N ASP 80.A OD1 no hydrogen 2.888 N/A GLN 101.A N ASP 80.A OD2 no hydrogen 3.177 N/A GLN 101.A NE2 VAL 83.A O no hydrogen 3.151 N/A VAL 103.A N ASN 100.A O no hydrogen 3.130 N/A ILE 104.A N VAL 159.A O no hydrogen 3.073 N/A GLY 105.A N THR 91.A OG1 no hydrogen 2.985 N/A ASP 107.A N LEU 123.A O no hydrogen 2.967 N/A ASN 109.A N ASP 107.A OD1 no hydrogen 2.946 N/A ASN 109.A ND2 ASP 107.A OD1 no hydrogen 3.100 N/A ASN 109.A ND2 ASP 107.A OD2 no hydrogen 3.465 N/A THR 110.A N ASP 107.A O no hydrogen 2.979 N/A THR 110.A OG1 ASP 107.A O no hydrogen 3.014 N/A ARG 112.A NE ASP 161.A OD2 no hydrogen 2.815 N/A ARG 112.A NH2 ASP 161.A OD1 no hydrogen 3.153 N/A THR 113.A N ALA 160.A O no hydrogen 2.909 N/A THR 113.A OG1 ASP 161.A OD2 no hydrogen 2.773 N/A ASN 114.A N VAL 111.A O no hydrogen 2.965 N/A SER 116.A N ASN 114.A OD1 no hydrogen 3.128 N/A SER 116.A OG ASN 114.A OD1 no hydrogen 3.101 N/A TYR 117.A N ASN 114.A O no hydrogen 3.074 N/A GLN 118.A N CYS 115.A O no hydrogen 2.702 N/A GLN 118.A NE2 ASP 181.A O no hydrogen 3.042 N/A LEU 119.A N SER 116.A O no hydrogen 3.042 N/A ASP 120.A N TYR 117.A O no hydrogen 3.484 N/A SER 122.A N ASP 120.A OD1 no hydrogen 3.039 N/A SER 122.A OG ASP 120.A OD1 no hydrogen 2.605 N/A SER 122.A OG ASP 120.A OD2 no hydrogen 3.523 N/A LEU 123.A N ASP 120.A O no hydrogen 3.096 N/A PHE 124.A N GLU 121.A O no hydrogen 2.914 N/A THR 125.A N GLY 105.A O no hydrogen 2.953 N/A THR 125.A OG1 THR 95.A OG1 no hydrogen 3.140 N/A SER 127.A OG THR 155.A O no hydrogen 2.676 N/A ILE 128.A N LEU 94.A O no hydrogen 2.862 N/A HIS 130.A N SER 127.A OG no hydrogen 3.093 N/A HIS 130.A ND1 GLU 191.A OE1 no hydrogen 2.463 N/A TRP 131.A N SER 127.A O no hydrogen 3.125 N/A PHE 132.A N ILE 128.A O no hydrogen 2.864 N/A GLN 133.A N ALA 129.A O no hydrogen 2.992 N/A GLU 134.A N HIS 130.A O no hydrogen 2.818 N/A ALA 135.A N TRP 131.A O no hydrogen 3.143 N/A ALA 135.A N PHE 132.A O no hydrogen 3.016 N/A GLY 136.A N GLN 133.A O no hydrogen 2.735 N/A ARG 137.A N PHE 132.A O no hydrogen 2.971 N/A ARG 137.A NH1 ALA 466.A O no hydrogen 2.754 N/A ARG 137.A NH2 ALA 28.A O no hydrogen 2.745 N/A ARG 137.A NH2 LYS 29.A O no hydrogen 2.466 N/A ARG 137.A NH2 ALA 466.A O no hydrogen 3.528 N/A SER 138.A N GLY 304.A O no hydrogen 3.250 N/A SER 138.A OG ASP 301.A OD2 no hydrogen 2.741 N/A THR 139.A OG1 GLN 133.A OE1 no hydrogen 2.899 N/A GLY 140.A N PHE 306.A O no hydrogen 2.980 N/A VAL 141.A N VAL 198.A O no hydrogen 2.927 N/A VAL 142.A N LEU 308.A O no hydrogen 2.859 N/A THR 143.A N MET 200.A O no hydrogen 2.885 N/A THR 143.A OG1 THR 145.A OG1 no hydrogen 2.968 N/A THR 143.A OG1 GLU 310.A OE1 no hydrogen 2.849 N/A SER 144.A N GLU 310.A O no hydrogen 3.343 N/A THR 145.A N THR 143.A OG1 no hydrogen 2.942 N/A THR 145.A OG1 THR 143.A OG1 no hydrogen 2.968 N/A THR 145.A OG1 ARG 146.A O no hydrogen 2.789 N/A THR 145.A OG1 GLU 310.A OE1 no hydrogen 3.371 N/A ARG 146.A N HIS 272.A ND1 no hydrogen 3.138 N/A ARG 146.A NE GLU 165.A OE1 no hydrogen 2.865 N/A ARG 146.A NE GLU 165.A OE2 no hydrogen 3.469 N/A ARG 146.A NH1 THR 271.A OG1 no hydrogen 3.009 N/A ARG 146.A NH2 GLU 165.A OE2 no hydrogen 2.828 N/A VAL 147.A N GLY 202.A O no hydrogen 2.873 N/A THR 148.A OG1 GLU 165.A OE1 no hydrogen 2.370 N/A HIS 149.A N ARG 146.A O no hydrogen 3.026 N/A HIS 149.A NE2 ASP 37.A OD2 no hydrogen 3.329 N/A THR 151.A OG1 ASP 37.A OD2 no hydrogen 3.015 N/A THR 151.A OG1 HIS 149.A NE2 no hydrogen 3.237 N/A THR 151.A OG1 GLU 310.A OE2 no hydrogen 2.844 N/A ALA 153.A N HIS 149.A O no hydrogen 2.995 N/A GLY 154.A N ALA 150.A O no hydrogen 3.017 N/A GLY 154.A N THR 151.A O no hydrogen 3.132 N/A THR 155.A N PRO 152.A O no hydrogen 2.905 N/A THR 155.A OG1 PRO 152.A O no hydrogen 2.766 N/A TYR 156.A N ALA 153.A O no hydrogen 2.965 N/A TYR 156.A OH VAL 147.A O no hydrogen 2.786 N/A ALA 157.A N ALA 153.A O no hydrogen 2.754 N/A HIS 158.A N GLN 186.A OE1 no hydrogen 2.856 N/A HIS 158.A NE2 THR 125.A O no hydrogen 2.868 N/A VAL 159.A N ILE 104.A O no hydrogen 2.947 N/A ALA 160.A N GLN 118.A OE1 no hydrogen 3.100 N/A ARG 162.A N GLY 102.A O no hydrogen 2.803 N/A ASP 163.A N ASP 161.A OD1 no hydrogen 2.793 N/A TRP 164.A N ASP 161.A O no hydrogen 3.031 N/A TRP 164.A NE1 ASP 173.A OD2 no hydrogen 2.784 N/A GLU 165.A N ASP 163.A O no hydrogen 2.863 N/A ASN 166.A N ASP 169.A OD2 no hydrogen 2.978 N/A ASN 166.A ND2 GLU 222.A OE1 no hydrogen 2.886 N/A SER 168.A N ASN 166.A OD1 no hydrogen 2.887 N/A SER 168.A OG ASN 166.A OD1 no hydrogen 2.895 N/A ASP 169.A N ASN 166.A O no hydrogen 3.030 N/A VAL 171.A N ASP 167.A O no hydrogen 3.068 N/A HIS 172.A N SER 168.A O no hydrogen 3.104 N/A ASP 173.A N VAL 170.A O no hydrogen 3.025 N/A ARG 174.A N VAL 171.A O no hydrogen 2.853 N/A GLU 175.A N VAL 170.A O no hydrogen 3.124 N/A GLU 178.A N ASP 176.A OD1 no hydrogen 3.015 N/A ILE 179.A N ASP 176.A O no hydrogen 2.970 N/A CYS 180.A N ASP 176.A O no hydrogen 2.788 N/A CYS 180.A SG ASP 176.A O no hydrogen 3.327 N/A ILE 183.A N TRP 164.A O no hydrogen 2.920 N/A ALA 184.A N GLU 165.A O no hydrogen 2.876 N/A GLU 185.A N ASP 182.A OD2 no hydrogen 3.102 N/A GLN 186.A N ASP 182.A O no hydrogen 3.001 N/A GLN 186.A NE2 HIS 158.A O no hydrogen 2.963 N/A GLN 186.A NE2 ASP 181.A O no hydrogen 3.089 N/A LEU 187.A N ILE 183.A O no hydrogen 2.952 N/A VAL 188.A N ALA 184.A O no hydrogen 3.369 N/A VAL 188.A N GLU 185.A O no hydrogen 3.239 N/A PHE 189.A N GLU 185.A O no hydrogen 2.858 N/A ARG 190.A N GLN 186.A O no hydrogen 3.061 N/A ARG 190.A NH1 ASP 181.A OD2 no hydrogen 3.044 N/A LYS 194.A N ARG 190.A O no hydrogen 2.845 N/A ASN 195.A N PRO 192.A O no hydrogen 3.050 N/A PHE 196.A N GLY 193.A O no hydrogen 3.078 N/A LYS 197.A N THR 139.A O no hydrogen 2.917 N/A ILE 199.A N LEU 264.A O no hydrogen 2.939 N/A MET 200.A N VAL 141.A O no hydrogen 2.928 N/A GLY 201.A N GLY 266.A O no hydrogen 2.993 N/A GLY 202.A N THR 145.A O no hydrogen 2.875 N/A GLY 203.A N THR 271.A O no hydrogen 2.716 N/A ARG 204.A N SER 269.A O no hydrogen 2.960 N/A ARG 204.A NE ASP 214.A OD1 no hydrogen 2.933 N/A ARG 204.A NH1 GLU 216.A OE1 no hydrogen 3.046 N/A ARG 204.A NH1 LEU 267.A O no hydrogen 3.011 N/A ARG 204.A NH2 ASP 214.A OD2 no hydrogen 2.918 N/A ARG 204.A NH2 GLU 216.A OE1 no hydrogen 2.952 N/A ARG 205.A N TYR 270.A O no hydrogen 3.053 N/A GLY 206.A N GLY 203.A O no hydrogen 3.132 N/A PHE 207.A N ARG 204.A O no hydrogen 2.844 N/A GLU 210.A N ARG 223.A O no hydrogen 2.875 N/A ALA 212.A N PRO 209.A O no hydrogen 2.997 N/A ASP 214.A N ILE 219.A O no hydrogen 2.817 N/A GLY 218.A N ASP 214.A O no hydrogen 2.803 N/A GLY 221.A N ALA 212.A O no hydrogen 3.064 N/A GLU 222.A N ARG 205.A O no hydrogen 3.030 N/A ARG 223.A N PHE 208.A O no hydrogen 3.193 N/A ARG 223.A NE ASP 225.A OD1 no hydrogen 2.942 N/A ARG 223.A NH1 ASP 182.A OD2 no hydrogen 2.861 N/A ARG 223.A NH1 GLY 206.A O no hydrogen 2.975 N/A ARG 223.A NH2 ASP 182.A OD1 no hydrogen 2.935 N/A ARG 223.A NH2 ASP 182.A OD2 no hydrogen 3.286 N/A ARG 223.A NH2 ASP 225.A OD2 no hydrogen 2.794 N/A GLU 224.A N ASP 167.A OD1 no hydrogen 3.398 N/A GLU 224.A N ASP 167.A OD2 no hydrogen 2.823 N/A LYS 227.A N ASP 225.A OD1 no hydrogen 3.121 N/A LYS 227.A NZ GLU 185.A OE2 no hydrogen 2.927 N/A LYS 227.A NZ ASP 225.A OD2 no hydrogen 2.730 N/A LEU 229.A N PHE 207.A O no hydrogen 2.972 N/A THR 231.A OG1 HIS 228.A O no hydrogen 3.212 N/A ASP 232.A N HIS 228.A O no hydrogen 3.152 N/A TRP 233.A N LEU 229.A O no hydrogen 2.904 N/A LEU 234.A N ILE 230.A O no hydrogen 2.881 N/A ASP 235.A N THR 231.A O no hydrogen 2.845 N/A ASP 236.A N ASP 232.A O no hydrogen 2.938 N/A LYS 237.A N TRP 233.A O no hydrogen 3.168 N/A ALA 238.A N LEU 234.A O no hydrogen 3.050 N/A SER 239.A N ASP 235.A O no hydrogen 2.762 N/A SER 239.A OG ASP 235.A O no hydrogen 3.398 N/A SER 239.A OG ASP 236.A O no hydrogen 3.130 N/A GLN 240.A N ASP 236.A O no hydrogen 3.163 N/A GLN 240.A N LYS 237.A O no hydrogen 3.039 N/A GLN 240.A NE2 ASP 236.A OD1 no hydrogen 3.164 N/A GLY 241.A N ALA 238.A O no hydrogen 2.897 N/A ALA 242.A N LYS 237.A O no hydrogen 2.949 N/A THR 243.A N ASP 262.A OD2 no hydrogen 2.934 N/A THR 243.A OG1 ASN 260.A O no hydrogen 2.621 N/A THR 243.A OG1 ASP 262.A OD2 no hydrogen 3.103 N/A SER 245.A N TYR 263.A O no hydrogen 3.095 N/A VAL 247.A N MET 265.A O no hydrogen 2.854 N/A ASN 249.A ND2 ASP 252.A OD2 no hydrogen 3.010 N/A ARG 250.A N MET 283.A O no hydrogen 2.913 N/A ARG 250.A NE GLU 289.A OE1 no hydrogen 2.913 N/A ARG 250.A NE GLU 289.A OE2 no hydrogen 3.236 N/A ARG 250.A NH2 GLU 289.A OE2 no hydrogen 2.719 N/A ASP 252.A N ASN 249.A OD1 no hydrogen 2.630 N/A LEU 253.A N ASN 249.A O no hydrogen 2.965 N/A LEU 254.A N ARG 250.A O no hydrogen 2.964 N/A ALA 255.A N ASP 251.A O no hydrogen 3.081 N/A ALA 255.A N ASP 252.A O no hydrogen 3.176 N/A VAL 256.A N LEU 253.A O no hydrogen 3.081 N/A ASN 260.A N ASP 257.A OD1 no hydrogen 3.180 N/A ASN 260.A ND2 ASP 257.A OD2 no hydrogen 2.822 N/A THR 261.A N ILE 258.A O no hydrogen 3.476 N/A THR 261.A OG1 ASP 257.A O no hydrogen 2.614 N/A ASP 262.A N THR 243.A O no hydrogen 3.022 N/A ASP 262.A N THR 243.A OG1 no hydrogen 3.087 N/A TYR 263.A N THR 243.A O no hydrogen 3.091 N/A LEU 264.A N LYS 197.A O no hydrogen 2.790 N/A MET 265.A N SER 245.A O no hydrogen 2.900 N/A GLY 266.A N ILE 199.A O no hydrogen 2.849 N/A LEU 267.A N VAL 247.A O no hydrogen 2.999 N/A PHE 268.A N GLY 201.A O no hydrogen 2.816 N/A SER 269.A OG HIS 272.A O no hydrogen 3.064 N/A TYR 270.A OH PRO 220.A O no hydrogen 2.586 N/A THR 271.A N SER 269.A OG no hydrogen 2.951 N/A HIS 272.A N THR 271.A OG1 no hydrogen 2.659 N/A LEU 273.A N SER 144.A O no hydrogen 2.948 N/A THR 275.A OG1 THR 278.A OG1 no hydrogen 2.740 N/A THR 275.A OG1 GLN 325.A OE1 no hydrogen 2.781 N/A VAL 276.A N GLU 329.A OE2 no hydrogen 2.706 N/A THR 278.A N THR 275.A O no hydrogen 2.944 N/A THR 278.A OG1 THR 275.A O no hydrogen 3.354 N/A THR 278.A OG1 THR 275.A OG1 no hydrogen 2.740 N/A ARG 279.A N THR 275.A O no hydrogen 2.762 N/A ARG 279.A NH1 ASP 332.A OD2 no hydrogen 2.851 N/A ARG 279.A NH2 ASP 332.A OD1 no hydrogen 2.901 N/A ARG 279.A NH2 ASP 332.A OD2 no hydrogen 3.549 N/A GLU 282.A N ASP 280.A OD1 no hydrogen 2.982 N/A MET 283.A N ASP 280.A O no hydrogen 3.037 N/A ASP 284.A N ASP 280.A O no hydrogen 2.997 N/A THR 286.A N GLU 289.A OE1 no hydrogen 2.918 N/A LEU 287.A N ASP 332.A OD2 no hydrogen 3.015 N/A GLU 289.A N THR 286.A OG1 no hydrogen 3.088 N/A MET 290.A N THR 286.A O no hydrogen 2.948 N/A THR 291.A N LEU 287.A O no hydrogen 2.934 N/A THR 291.A OG1 LEU 287.A O no hydrogen 2.934 N/A LYS 292.A N PRO 288.A O no hydrogen 2.775 N/A LYS 292.A NZ GLU 296.A OE2 no hydrogen 3.368 N/A VAL 293.A N GLU 289.A O no hydrogen 3.207 N/A ALA 294.A N MET 290.A O no hydrogen 2.951 N/A ILE 295.A N THR 291.A O no hydrogen 2.867 N/A GLU 296.A N LYS 292.A O no hydrogen 2.864 N/A MET 297.A N VAL 293.A O no hydrogen 2.983 N/A LEU 298.A N ALA 294.A O no hydrogen 3.008 N/A THR 299.A N ILE 295.A O no hydrogen 2.938 N/A THR 299.A OG1 ILE 295.A O no hydrogen 2.705 N/A THR 299.A OG1 GLU 296.A O no hydrogen 3.298 N/A LYS 300.A N MET 297.A O no hydrogen 3.330 N/A LYS 300.A NZ ILE 258.A O no hydrogen 2.726 N/A LYS 300.A NZ ALA 259.A O no hydrogen 3.319 N/A LYS 300.A NZ THR 261.A O no hydrogen 2.869 N/A ASP 301.A N LEU 298.A O no hydrogen 3.033 N/A ASN 303.A N ASP 301.A OD1 no hydrogen 2.870 N/A GLY 304.A N ASP 301.A O no hydrogen 3.021 N/A PHE 305.A N ASN 30.A OD1 no hydrogen 2.832 N/A PHE 306.A N SER 138.A O no hydrogen 2.872 N/A LEU 307.A N VAL 31.A O no hydrogen 2.998 N/A LEU 308.A N GLY 140.A O no hydrogen 3.082 N/A VAL 309.A N PHE 33.A O no hydrogen 2.822 N/A GLU 310.A N VAL 142.A O no hydrogen 2.798 N/A GLY 311.A N LEU 35.A O no hydrogen 2.814 N/A GLY 312.A N SER 144.A OG no hydrogen 2.961 N/A ARG 313.A NE HIS 316.A ND1 no hydrogen 2.869 N/A ARG 313.A NH1 LEU 273.A O no hydrogen 2.798 N/A ARG 313.A NH2 HIS 316.A ND1 no hydrogen 3.458 N/A MET 317.A N ARG 313.A O no hydrogen 2.937 N/A HIS 318.A N ILE 314.A O no hydrogen 3.113 N/A HIS 318.A ND1 TYR 392.A OH no hydrogen 2.819 N/A HIS 318.A NE2 THR 43.A OG1 no hydrogen 2.897 N/A HIS 319.A N ASP 315.A O no hydrogen 2.861 N/A HIS 319.A ND1 ALA 430.A O no hydrogen 2.693 N/A HIS 319.A NE2 ASP 315.A OD2 no hydrogen 2.889 N/A ALA 320.A N HIS 316.A O no hydrogen 3.419 N/A ALA 320.A N MET 317.A O no hydrogen 3.216 N/A ASN 321.A N HIS 318.A O no hydrogen 2.750 N/A ASN 321.A ND2 HIS 318.A O no hydrogen 3.292 N/A ASN 321.A ND2 SER 394.A O no hydrogen 3.006 N/A GLN 322.A N MET 317.A O no hydrogen 2.787 N/A GLN 325.A NE2 ILE 417.A O no hydrogen 2.988 N/A SER 326.A N GLN 322.A O no hydrogen 3.106 N/A SER 326.A OG ILE 314.A O no hydrogen 3.001 N/A LEU 327.A N ILE 323.A O no hydrogen 2.989 N/A ALA 328.A N ARG 324.A O no hydrogen 3.137 N/A GLU 329.A N GLN 325.A O no hydrogen 2.985 N/A THR 330.A N SER 326.A O no hydrogen 3.066 N/A THR 330.A OG1 SER 326.A O no hydrogen 2.903 N/A LEU 331.A N LEU 327.A O no hydrogen 2.947 N/A ASP 332.A N ALA 328.A O no hydrogen 3.099 N/A MET 333.A N GLU 329.A O no hydrogen 3.274 N/A MET 333.A N THR 330.A O no hydrogen 3.025 N/A GLU 334.A N THR 330.A O no hydrogen 3.013 N/A GLU 335.A N LEU 331.A O no hydrogen 2.878 N/A ALA 336.A N ASP 332.A O no hydrogen 3.136 N/A VAL 337.A N MET 333.A O no hydrogen 3.014 N/A SER 338.A N GLU 334.A O no hydrogen 3.204 N/A SER 338.A OG GLU 334.A O no hydrogen 3.424 N/A MET 339.A N GLU 335.A O no hydrogen 2.875 N/A ALA 340.A N ALA 336.A O no hydrogen 2.913 N/A LEU 341.A N VAL 337.A O no hydrogen 2.842 N/A SER 342.A N SER 338.A O no hydrogen 3.142 N/A SER 342.A OG MET 339.A O no hydrogen 2.746 N/A MET 343.A N ALA 340.A O no hydrogen 3.074 N/A THR 344.A OG1 ALA 340.A O no hydrogen 2.506 N/A GLU 347.A N ASP 345.A OD1 no hydrogen 2.991 N/A GLU 348.A N ASP 345.A O no hydrogen 2.774 N/A THR 349.A N ASP 345.A O no hydrogen 2.727 N/A THR 349.A OG1 ASP 345.A O no hydrogen 3.183 N/A ILE 350.A N ASN 30.A O no hydrogen 2.998 N/A ILE 351.A N ASN 442.A O no hydrogen 2.963 N/A LEU 352.A N ILE 32.A O no hydrogen 2.963 N/A VAL 353.A N TRP 440.A O no hydrogen 2.822 N/A THR 354.A N PHE 34.A O no hydrogen 2.929 N/A THR 354.A OG1 ALA 355.A O no hydrogen 3.430 N/A THR 354.A OG1 GLY 438.A O no hydrogen 2.662 N/A ALA 355.A N THR 354.A OG1 no hydrogen 2.814 N/A HIS 357.A ND1 GLY 358.A O no hydrogen 2.906 N/A HIS 357.A NE2 SER 86.A OG no hydrogen 3.084 N/A THR 362.A N ASP 391.A O no hydrogen 2.866 N/A THR 362.A OG1 ASP 391.A OD1 no hydrogen 2.686 N/A THR 364.A N ILE 389.A O no hydrogen 2.678 N/A THR 364.A OG1 THR 388.A O no hydrogen 3.197 N/A THR 364.A OG1 ILE 389.A O no hydrogen 2.962 N/A ARG 369.A NE GLU 59.A OE1 no hydrogen 2.870 N/A ARG 369.A NH1 GLU 2.A OE1 no hydrogen 2.851 N/A ARG 369.A NH2 GLU 2.A OE1 no hydrogen 3.558 N/A ARG 369.A NH2 GLU 2.A OE2 no hydrogen 2.941 N/A ASN 370.A N GLU 59.A OE1 no hydrogen 3.111 N/A ASN 370.A N GLU 59.A OE2 no hydrogen 3.107 N/A ASN 370.A ND2 GLU 59.A OE1 no hydrogen 3.492 N/A THR 371.A N ASP 368.A O no hydrogen 3.191 N/A THR 371.A OG1 ASP 368.A O no hydrogen 2.710 N/A LEU 374.A N ASP 372.A OD1 no hydrogen 2.897 N/A ASP 375.A N ASP 372.A O no hydrogen 2.773 N/A PHE 376.A N ASP 375.A OD1 no hydrogen 2.770 N/A ALA 377.A N TYR 387.A O no hydrogen 2.856 N/A SER 380.A N ARG 385.A O no hydrogen 2.952 N/A LEU 382.A N SER 380.A OG no hydrogen 2.925 N/A ASP 383.A N SER 380.A OG no hydrogen 3.225 N/A ASP 384.A N SER 380.A O no hydrogen 3.096 N/A ARG 385.A N ASP 383.A OD1 no hydrogen 2.962 N/A ARG 385.A NH1 ARG 406.A O no hydrogen 3.223 N/A ARG 386.A N GLU 408.A OE2 no hydrogen 2.693 N/A ARG 386.A NE PRO 409.A O no hydrogen 3.071 N/A ARG 386.A NH2 PRO 409.A O no hydrogen 2.793 N/A TYR 387.A N GLY 378.A O no hydrogen 3.007 N/A TYR 387.A OH GLY 365.A O no hydrogen 2.837 N/A THR 388.A OG1 LEU 390.A O no hydrogen 2.777 N/A ILE 389.A N ASP 375.A O no hydrogen 3.276 N/A ASP 391.A N THR 362.A O no hydrogen 3.207 N/A TYR 392.A N ALA 422.A O no hydrogen 2.801 N/A TYR 392.A OH HIS 318.A ND1 no hydrogen 2.819 N/A GLY 393.A N THR 360.A O no hydrogen 2.902 N/A SER 394.A N THR 360.A OG1 no hydrogen 2.910 N/A GLY 395.A N ALA 425.A O no hydrogen 3.236 N/A GLY 397.A N ASN 321.A OD1 no hydrogen 2.802 N/A THR 401.A N LYS 405.A O no hydrogen 2.743 N/A THR 401.A OG1 ASP 403.A OD1 no hydrogen 2.856 N/A THR 401.A OG1 LYS 405.A O no hydrogen 3.211 N/A ASP 403.A N ASP 403.A OD1 no hydrogen 2.586 N/A GLY 404.A N THR 401.A O no hydrogen 2.875 N/A LYS 405.A N THR 401.A OG1 no hydrogen 3.057 N/A ARG 406.A NE ASP 383.A OD2 no hydrogen 2.835 N/A ARG 406.A NH1 ARG 386.A O no hydrogen 2.909 N/A ARG 406.A NH2 ASP 383.A OD1 no hydrogen 2.908 N/A ARG 406.A NH2 ASP 383.A OD2 no hydrogen 3.304 N/A ARG 406.A NH2 ARG 385.A O no hydrogen 2.810 N/A ARG 406.A NH2 ARG 386.A O no hydrogen 3.254 N/A TYR 407.A N HIS 399.A O no hydrogen 2.899 N/A TYR 407.A OH ASP 413.A OD1 no hydrogen 3.242 N/A TYR 407.A OH ASP 413.A OD2 no hydrogen 2.458 N/A THR 410.A N ASP 413.A OD2 no hydrogen 2.874 N/A ASP 413.A N THR 410.A OG1 no hydrogen 3.078 N/A LEU 414.A N THR 410.A O no hydrogen 3.042 N/A ASP 416.A N GLU 412.A O no hydrogen 3.203 N/A ASP 416.A N ASP 413.A O no hydrogen 2.952 N/A ASN 418.A N ASP 416.A OD1 no hydrogen 2.744 N/A PHE 419.A N ASP 416.A O no hydrogen 2.832 N/A TYR 421.A N ASN 321.A O no hydrogen 2.928 N/A TYR 421.A OH LEU 374.A O no hydrogen 2.725 N/A SER 423.A OG GLY 395.A O no hydrogen 2.696 N/A ALA 424.A N TYR 392.A O no hydrogen 2.915 N/A LYS 427.A N GLY 395.A O no hydrogen 3.225 N/A LYS 427.A NZ SER 429.A O no hydrogen 3.209 N/A SER 429.A OG HIS 319.A ND1 no hydrogen 2.980 N/A ALA 430.A N HIS 319.A O no hydrogen 2.945 N/A THR 431.A N SER 394.A OG no hydrogen 2.989 N/A THR 431.A OG1 HIS 432.A O no hydrogen 2.692 N/A HIS 432.A ND1 THR 84.A O no hydrogen 2.873 N/A ASP 433.A N GLY 358.A O no hydrogen 3.095 N/A THR 435.A N ASP 433.A OD1 no hydrogen 2.916 N/A THR 435.A OG1 ASP 433.A OD1 no hydrogen 2.755 N/A VAL 437.A N SER 74.A O no hydrogen 3.114 N/A ILE 439.A N ALA 72.A O no hydrogen 2.903 N/A TRP 440.A N VAL 353.A O no hydrogen 2.894 N/A VAL 441.A N PHE 70.A O no hydrogen 3.007 N/A ASN 442.A N ILE 351.A O no hydrogen 2.900 N/A PHE 445.A N ARG 24.A O no hydrogen 2.829 N/A ALA 446.A N GLY 443.A O no hydrogen 3.091 N/A LEU 448.A N PHE 445.A O no hydrogen 3.024 N/A PHE 449.A N ALA 446.A O no hydrogen 3.050 N/A THR 450.A N TYR 453.A OH no hydrogen 2.961 N/A THR 450.A OG1 TYR 453.A OH no hydrogen 3.319 N/A GLY 451.A N TYR 453.A OH no hydrogen 3.052 N/A TYR 453.A N LEU 73.A O no hydrogen 2.770 N/A GLU 455.A N LYS 75.A O no hydrogen 3.076 N/A ASN 456.A ND2 GLY 96.A O no hydrogen 2.952 N/A TYR 457.A N GLU 454.A O no hydrogen 2.975 N/A TYR 457.A OH LEU 448.A O no hydrogen 2.667 N/A ILE 458.A N GLU 455.A O no hydrogen 3.358 N/A HIS 460.A NE2 GLY 96.A O no hydrogen 3.029 N/A ALA 461.A N TYR 457.A O no hydrogen 3.148 N/A LEU 462.A N ILE 458.A O no hydrogen 2.945 N/A ALA 463.A N PRO 459.A O no hydrogen 2.846 N/A TYR 464.A N HIS 460.A O no hydrogen 3.106 N/A ALA 465.A N ALA 461.A O no hydrogen 3.215 N/A ALA 466.A N LEU 462.A O no hydrogen 2.889 N/A CYS 467.A SG TYR 464.A O no hydrogen 4.033 N/A VAL 468.A N ALA 463.A O no hydrogen 3.102 N/A PHE 474.A N TYR 464.A O no hydrogen 2.965 N/A CYS 475.A SG GLN 27.A OE1 no hydrogen 3.703 N/A ASP 476.A N THR 473.A O no hydrogen 3.019 N/A