Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 1lew_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 1.A NH2 PRO 88.A O no hydrogen 3.307 N/A THR 3.A OG1 GLU 18.A OE2 no hydrogen 3.376 N/A TYR 5.A N VAL 16.A O no hydrogen 3.056 N/A TYR 5.A OH TYR 20.A O no hydrogen 2.636 N/A GLN 7.A N TRP 14.A O no hydrogen 3.021 N/A LEU 9.A N THR 12.A O no hydrogen 2.989 N/A THR 12.A N LEU 9.A O no hydrogen 2.403 N/A TRP 14.A N GLN 7.A O no hydrogen 2.759 N/A GLU 15.A N TYR 99.A OH no hydrogen 2.883 N/A VAL 16.A N TYR 5.A O no hydrogen 3.405 N/A GLU 18.A N THR 3.A O no hydrogen 2.827 N/A ARG 19.A NE ASP 39.A OD1 no hydrogen 2.724 N/A ARG 19.A NH2 ASP 39.A OD1 no hydrogen 3.444 N/A ARG 19.A NH2 ASP 39.A OD2 no hydrogen 3.033 N/A TYR 20.A N PRO 17.A O no hydrogen 3.032 N/A TYR 20.A OH ASP 84.A OD2 no hydrogen 2.839 N/A GLN 21.A N PHE 38.A O no hydrogen 3.016 N/A GLN 21.A NE2 GLU 18.A O no hydrogen 2.656 N/A SER 24.A N ALA 36.A O no hydrogen 2.521 N/A VAL 26.A N VAL 34.A O no hydrogen 2.866 N/A GLY 27.A N VAL 34.A O no hydrogen 3.350 N/A SER 28.A OG GLY 27.A O no hydrogen 2.966 N/A VAL 34.A N GLY 27.A O no hydrogen 2.900 N/A CYS 35.A N VAL 48.A O no hydrogen 2.703 N/A ALA 36.A N SER 24.A O no hydrogen 2.775 N/A ALA 37.A N VAL 46.A O no hydrogen 3.169 N/A PHE 38.A N GLN 21.A O no hydrogen 2.919 N/A ASP 39.A N HIS 44.A O no hydrogen 2.814 N/A THR 40.A N ARG 19.A O no hydrogen 2.955 N/A THR 40.A OG1 ARG 19.A O no hydrogen 3.172 N/A LYS 41.A N ASP 39.A OD1 no hydrogen 3.211 N/A THR 42.A N ASP 39.A O no hydrogen 3.132 N/A THR 42.A N ASP 39.A OD2 no hydrogen 3.193 N/A THR 42.A OG1 ASP 39.A OD2 no hydrogen 2.630 N/A GLY 43.A N ASP 39.A O no hydrogen 2.701 N/A HIS 44.A N THR 42.A OG1 no hydrogen 3.353 N/A VAL 46.A N ALA 37.A O no hydrogen 2.870 N/A ALA 47.A N THR 102.A O no hydrogen 2.679 N/A VAL 48.A N CYS 35.A O no hydrogen 2.809 N/A LYS 49.A N LEU 100.A O no hydrogen 2.728 N/A LYS 50.A N SER 33.A O no hydrogen 2.924 N/A LYS 50.A NZ ILE 13.A O no hydrogen 2.562 N/A LEU 51.A N VAL 98.A O no hydrogen 3.089 N/A SER 52.A N TYR 31.A O no hydrogen 2.750 N/A SER 57.A OG HIS 60.A ND1 no hydrogen 2.770 N/A HIS 60.A N SER 57.A OG no hydrogen 3.124 N/A HIS 60.A ND1 SER 57.A OG no hydrogen 2.770 N/A ALA 61.A N SER 57.A O no hydrogen 2.906 N/A LYS 62.A N ILE 58.A O no hydrogen 2.927 N/A LYS 62.A NZ GLU 315.A O no hydrogen 2.738 N/A ARG 63.A N ILE 59.A O no hydrogen 2.935 N/A ARG 63.A NH2 ALA 168.A O no hydrogen 2.456 N/A THR 64.A N HIS 60.A O no hydrogen 2.766 N/A THR 64.A OG1 PRO 54.A O no hydrogen 2.917 N/A THR 64.A OG1 HIS 60.A O no hydrogen 2.925 N/A TYR 65.A N ALA 61.A O no hydrogen 2.946 N/A ARG 66.A N LYS 62.A O no hydrogen 2.971 N/A ARG 66.A NE GLU 315.A OE1 no hydrogen 3.313 N/A ARG 66.A NE GLU 315.A OE2 no hydrogen 2.669 N/A ARG 66.A NH2 GLU 315.A OE1 no hydrogen 2.989 N/A GLU 67.A N ARG 63.A O no hydrogen 3.028 N/A LEU 68.A N THR 64.A O no hydrogen 3.035 N/A ARG 69.A N TYR 65.A O no hydrogen 2.950 N/A ARG 69.A NH1 TYR 65.A OH no hydrogen 2.983 N/A ARG 69.A NH2 ASP 311.A O no hydrogen 2.928 N/A LEU 70.A N ARG 66.A O no hydrogen 2.943 N/A LEU 71.A N GLU 67.A O no hydrogen 2.969 N/A LYS 72.A N LEU 68.A O no hydrogen 3.084 N/A LYS 72.A NZ GLU 331.A O no hydrogen 2.963 N/A LYS 72.A NZ GLU 331.A OE1 no hydrogen 2.966 N/A HIS 73.A N ARG 69.A O no hydrogen 3.349 N/A HIS 73.A N LEU 70.A O no hydrogen 3.225 N/A MET 74.A N LEU 70.A O no hydrogen 3.309 N/A MET 74.A N LEU 71.A O no hydrogen 3.387 N/A LYS 75.A N TYR 136.A OH no hydrogen 2.918 N/A ASN 78.A ND2 GLN 129.A OE1 no hydrogen 3.369 N/A ASN 78.A ND2 LEU 160.A O no hydrogen 2.980 N/A VAL 79.A N HIS 76.A O no hydrogen 3.159 N/A ILE 80.A N ILE 162.A O no hydrogen 2.970 N/A LEU 83.A N VAL 101.A O no hydrogen 2.904 N/A ASP 84.A N VAL 101.A O no hydrogen 3.337 N/A PHE 86.A N TYR 99.A O no hydrogen 3.084 N/A THR 87.A OG1 ASP 97.A O no hydrogen 2.926 N/A ALA 89.A N THR 87.A OG1 no hydrogen 3.126 N/A ARG 90.A N GLU 94.A OE1 no hydrogen 2.694 N/A GLU 94.A N SER 91.A O no hydrogen 3.296 N/A PHE 95.A N LEU 92.A O no hydrogen 2.914 N/A ASN 96.A ND2 GLU 94.A O no hydrogen 3.474 N/A TYR 99.A N PHE 86.A O no hydrogen 2.932 N/A LEU 100.A N LYS 49.A O no hydrogen 2.758 N/A VAL 101.A N ASP 84.A O no hydrogen 2.767 N/A THR 102.A N ALA 47.A O no hydrogen 3.017 N/A LEU 109.A N PRO 149.A O no hydrogen 3.248 N/A LEU 109.A N LEU 152.A O no hydrogen 2.698 N/A ASN 111.A N ASP 108.A OD1 no hydrogen 2.895 N/A ILE 112.A N ASP 108.A O no hydrogen 3.300 N/A ILE 112.A N LEU 109.A O no hydrogen 3.033 N/A VAL 113.A N LEU 109.A O no hydrogen 3.075 N/A LYS 114.A N ASN 110.A O no hydrogen 2.985 N/A CYS 115.A N ILE 112.A O no hydrogen 2.805 N/A CYS 115.A SG ASN 111.A O no hydrogen 3.582 N/A GLN 116.A N ILE 112.A O no hydrogen 3.218 N/A GLN 116.A NE2 ILE 112.A O no hydrogen 3.134 N/A LYS 117.A NZ LEU 118.A O no hydrogen 3.568 N/A THR 119.A N HIS 122.A ND1 no hydrogen 2.903 N/A THR 119.A OG1 HIS 122.A ND1 no hydrogen 2.800 N/A HIS 122.A N THR 119.A OG1 no hydrogen 3.238 N/A VAL 123.A N THR 119.A O no hydrogen 3.231 N/A GLN 124.A N ASP 120.A O no hydrogen 3.041 N/A GLN 124.A NE2 ASP 120.A OD2 no hydrogen 3.117 N/A PHE 125.A N ASP 121.A O no hydrogen 3.007 N/A LEU 126.A N HIS 122.A O no hydrogen 2.772 N/A ILE 127.A N VAL 123.A O no hydrogen 2.812 N/A TYR 128.A N GLN 124.A O no hydrogen 2.895 N/A TYR 128.A OH GLU 304.A OE2 no hydrogen 2.603 N/A GLN 129.A N PHE 125.A O no hydrogen 3.086 N/A GLN 129.A NE2 PHE 125.A O no hydrogen 3.363 N/A GLN 129.A NE2 CYS 158.A O no hydrogen 2.762 N/A ILE 130.A N LEU 126.A O no hydrogen 3.139 N/A LEU 131.A N ILE 127.A O no hydrogen 2.988 N/A ARG 132.A N TYR 128.A O no hydrogen 2.815 N/A ARG 132.A NE ASP 303.A O no hydrogen 2.803 N/A ARG 132.A NH1 GLU 77.A OE1 no hydrogen 3.562 N/A ARG 132.A NH1 ASN 78.A OD1 no hydrogen 2.919 N/A ARG 132.A NH2 ASP 303.A O no hydrogen 2.849 N/A ARG 132.A NH2 ASP 303.A OD1 no hydrogen 3.316 N/A GLY 133.A N GLN 129.A O no hydrogen 2.969 N/A LEU 134.A N ILE 130.A O no hydrogen 2.913 N/A LYS 135.A N LEU 131.A O no hydrogen 2.816 N/A LYS 135.A NZ GLU 304.A O no hydrogen 2.624 N/A TYR 136.A N ARG 132.A O no hydrogen 3.376 N/A TYR 136.A OH HIS 73.A O no hydrogen 3.149 N/A ILE 137.A N GLY 133.A O no hydrogen 2.944 N/A HIS 138.A N LEU 134.A O no hydrogen 2.767 N/A HIS 138.A NE2 ASP 192.A OD2 no hydrogen 2.914 N/A SER 139.A N LYS 135.A O no hydrogen 3.065 N/A SER 139.A OG LYS 135.A O no hydrogen 3.341 N/A SER 139.A OG TYR 136.A O no hydrogen 2.511 N/A ALA 140.A N ILE 137.A O no hydrogen 3.095 N/A ASP 141.A N HIS 138.A O no hydrogen 2.948 N/A ILE 142.A N ILE 137.A O no hydrogen 3.283 N/A HIS 144.A N ASP 192.A OD2 no hydrogen 2.977 N/A HIS 144.A NE2 LEU 163.A O no hydrogen 2.769 N/A ARG 145.A N ASP 192.A OD1 no hydrogen 3.001 N/A ASP 146.A N HIS 144.A ND1 no hydrogen 3.051 N/A LYS 148.A NZ THR 172.A OG1 no hydrogen 2.519 N/A ASN 151.A N LYS 148.A O no hydrogen 2.917 N/A ASN 151.A ND2 ASP 146.A O no hydrogen 2.834 N/A ASN 151.A ND2 ASP 146.A OD2 no hydrogen 3.354 N/A LEU 152.A N PRO 149.A O no hydrogen 3.142 N/A ALA 153.A N LYS 161.A O no hydrogen 3.170 N/A VAL 154.A N ALA 107.A O no hydrogen 2.643 N/A ASN 155.A N GLU 159.A O no hydrogen 2.936 N/A ASN 155.A ND2 GLU 159.A OE1 no hydrogen 2.832 N/A ASP 157.A N ASN 155.A OD1 no hydrogen 2.798 N/A CYS 158.A N ASN 155.A O no hydrogen 2.762 N/A GLU 159.A N ASN 155.A OD1 no hydrogen 3.013 N/A LEU 160.A N GLN 129.A OE1 no hydrogen 2.797 N/A LYS 161.A N ALA 153.A O no hydrogen 3.065 N/A LYS 161.A NZ GLU 77.A O no hydrogen 3.117 N/A ILE 162.A N ASN 78.A O no hydrogen 2.755 N/A LEU 163.A N ASN 151.A O no hydrogen 3.085 N/A GLY 166.A N HIS 144.A O no hydrogen 2.958 N/A ARG 169.A NH1 ALA 168.A O no hydrogen 3.223 N/A THR 172.A OG1 ASP 146.A OD1 no hydrogen 3.433 N/A ARG 173.A NE GLN 218.A OE1 no hydrogen 3.403 N/A TRP 174.A N ALA 171.A O no hydrogen 2.444 N/A TRP 174.A NE1 GLY 212.A O no hydrogen 2.962 N/A TYR 175.A N THR 172.A O no hydrogen 2.973 N/A TYR 175.A OH GLU 202.A OE1 no hydrogen 2.638 N/A TYR 175.A OH GLU 202.A OE2 no hydrogen 3.310 N/A ARG 176.A N ARG 173.A O no hydrogen 3.098 N/A ARG 176.A NH1 ARG 145.A O no hydrogen 2.842 N/A ARG 176.A NH2 ARG 145.A O no hydrogen 3.056 N/A GLU 179.A N GLU 179.A OE1 no hydrogen 2.590 N/A ILE 180.A N ALA 177.A O no hydrogen 3.127 N/A MET 181.A N ALA 177.A O no hydrogen 3.088 N/A LEU 182.A N PRO 178.A O no hydrogen 3.201 N/A ASN 183.A N ILE 180.A O no hydrogen 2.911 N/A TRP 184.A N GLU 179.A O no hydrogen 2.895 N/A THR 190.A N ASN 188.A OD1 no hydrogen 2.515 N/A THR 190.A OG1 ASN 188.A OD1 no hydrogen 2.541 N/A THR 190.A OG1 SER 280.A O no hydrogen 3.201 N/A VAL 191.A N ASN 188.A O no hydrogen 3.060 N/A ASP 192.A N GLN 189.A O no hydrogen 2.936 N/A TRP 194.A N THR 190.A O no hydrogen 2.992 N/A SER 195.A N VAL 191.A O no hydrogen 3.189 N/A SER 195.A OG TYR 175.A O no hydrogen 2.721 N/A SER 195.A OG VAL 191.A O no hydrogen 3.450 N/A VAL 196.A N ASP 192.A O no hydrogen 2.934 N/A GLY 197.A N ILE 193.A O no hydrogen 2.987 N/A CYS 198.A N TRP 194.A O no hydrogen 3.080 N/A CYS 198.A SG TRP 174.A O no hydrogen 3.900 N/A CYS 198.A SG TRP 194.A O no hydrogen 3.514 N/A ILE 199.A N SER 195.A O no hydrogen 2.897 N/A MET 200.A N VAL 196.A O no hydrogen 2.814 N/A ALA 201.A N GLY 197.A O no hydrogen 3.042 N/A GLU 202.A N CYS 198.A O no hydrogen 3.272 N/A LEU 203.A N ILE 199.A O no hydrogen 3.085 N/A LEU 204.A N MET 200.A O no hydrogen 3.040 N/A LEU 204.A N ALA 201.A O no hydrogen 3.169 N/A THR 205.A N ALA 201.A O no hydrogen 2.973 N/A THR 205.A OG1 ALA 201.A O no hydrogen 3.135 N/A GLY 206.A N GLU 202.A O no hydrogen 2.686 N/A ARG 207.A N THR 205.A OG1 no hydrogen 3.214 N/A ARG 207.A NH1 THR 205.A O no hydrogen 2.731 N/A THR 208.A OG1 GLU 202.A OE1 no hydrogen 3.427 N/A GLY 212.A N PHE 210.A O no hydrogen 2.767 N/A THR 213.A N ASP 217.A OD2 no hydrogen 2.681 N/A THR 213.A OG1 ASP 214.A OD2 no hydrogen 3.552 N/A THR 213.A OG1 ASP 217.A OD2 no hydrogen 3.211 N/A ASP 217.A N ASP 214.A OD1 no hydrogen 3.124 N/A GLN 218.A N ASP 214.A O no hydrogen 2.929 N/A GLN 218.A NE2 ARG 173.A O no hydrogen 2.785 N/A LEU 219.A N HIS 215.A O no hydrogen 2.989 N/A LYS 220.A N ILE 216.A O no hydrogen 3.027 N/A LEU 221.A N ASP 217.A O no hydrogen 3.237 N/A ILE 222.A N GLN 218.A O no hydrogen 2.875 N/A LEU 223.A N LEU 219.A O no hydrogen 2.759 N/A LEU 225.A N ILE 222.A O no hydrogen 2.934 N/A VAL 226.A N ILE 222.A O no hydrogen 3.113 N/A THR 228.A N MET 252.A O no hydrogen 3.037 N/A THR 228.A OG1 MET 252.A O no hydrogen 3.193 N/A LEU 234.A N GLY 230.A O no hydrogen 3.017 N/A LYS 235.A N ALA 231.A O no hydrogen 3.135 N/A LYS 236.A N LEU 233.A O no hydrogen 2.686 N/A LYS 236.A NZ ASP 279.A OD1 no hydrogen 3.360 N/A LYS 236.A NZ ASP 279.A OD2 no hydrogen 3.024 N/A LYS 236.A NZ ASP 281.A OD2 no hydrogen 2.732 N/A ILE 237.A N LEU 234.A O no hydrogen 2.967 N/A SER 238.A N TRP 184.A O no hydrogen 3.139 N/A ALA 242.A N SER 239.A OG no hydrogen 2.832 N/A ARG 243.A N SER 239.A O no hydrogen 2.990 N/A ARG 243.A NH1 ILE 237.A O no hydrogen 3.339 N/A ASN 244.A N GLU 240.A O no hydrogen 3.008 N/A TYR 245.A N SER 241.A O no hydrogen 2.972 N/A ILE 246.A N ALA 242.A O no hydrogen 2.969 N/A GLN 247.A N ARG 243.A O no hydrogen 3.075 N/A SER 248.A N TYR 245.A O no hydrogen 3.081 N/A SER 248.A OG TYR 245.A O no hydrogen 2.647 N/A LEU 249.A N ILE 246.A O no hydrogen 2.966 N/A MET 252.A N THR 228.A OG1 no hydrogen 2.567 N/A LYS 254.A NZ MET 255.A O no hydrogen 2.616 N/A LYS 254.A NZ GLU 273.A OE1 no hydrogen 3.063 N/A MET 255.A N LEU 225.A O no hydrogen 2.854 N/A PHE 257.A N GLU 273.A OE1 no hydrogen 3.336 N/A ALA 258.A N ASN 256.A OD1 no hydrogen 2.753 N/A ASN 259.A N ASN 256.A O no hydrogen 2.860 N/A VAL 260.A N PHE 257.A O no hydrogen 2.906 N/A PHE 261.A N PHE 257.A O no hydrogen 2.911 N/A ALA 264.A N PHE 261.A O no hydrogen 3.140 N/A ASN 265.A ND2 ASP 120.A OD2 no hydrogen 3.177 N/A LEU 267.A N ASN 265.A OD1 no hydrogen 2.641 N/A VAL 269.A N ASN 265.A O no hydrogen 3.009 N/A ASP 270.A N PRO 266.A O no hydrogen 3.014 N/A LEU 271.A N LEU 267.A O no hydrogen 3.081 N/A LEU 272.A N ALA 268.A O no hydrogen 2.989 N/A GLU 273.A N VAL 269.A O no hydrogen 3.092 N/A LYS 274.A N ASP 270.A O no hydrogen 3.057 N/A MET 275.A N LEU 271.A O no hydrogen 2.965 N/A MET 275.A N LEU 272.A O no hydrogen 3.017 N/A LEU 276.A N LEU 272.A O no hydrogen 2.834 N/A ASP 281.A N ASP 279.A OD1 no hydrogen 2.823 N/A LYS 282.A N ASP 279.A O no hydrogen 3.102 N/A LYS 282.A NZ GLU 232.A OE1 no hydrogen 2.629 N/A LYS 282.A NZ GLU 232.A OE2 no hydrogen 3.498 N/A ARG 283.A N SER 280.A O no hydrogen 3.370 N/A ARG 283.A NE VAL 277.A O no hydrogen 2.710 N/A ARG 283.A NH1 GLU 179.A OE2 no hydrogen 2.904 N/A ARG 283.A NH1 THR 190.A O no hydrogen 3.207 N/A ARG 283.A NH2 GLU 179.A OE1 no hydrogen 2.832 N/A ARG 283.A NH2 GLU 179.A OE2 no hydrogen 3.062 N/A ARG 283.A NH2 LEU 278.A O no hydrogen 3.180 N/A ILE 284.A N LYS 274.A O no hydrogen 3.176 N/A THR 285.A N GLN 288.A OE1 no hydrogen 3.015 N/A GLN 288.A N THR 285.A OG1 no hydrogen 3.342 N/A ALA 289.A N THR 285.A O no hydrogen 2.860 N/A LEU 290.A N ALA 286.A O no hydrogen 3.138 N/A ALA 291.A N GLN 288.A O no hydrogen 3.146 N/A HIS 292.A N ALA 289.A O no hydrogen 2.864 N/A HIS 292.A NE2 ASP 270.A OD2 no hydrogen 2.964 N/A TYR 294.A N HIS 292.A ND1 no hydrogen 2.958 N/A TYR 294.A OH ASP 120.A OD1 no hydrogen 2.840 N/A PHE 295.A N HIS 292.A O no hydrogen 2.843 N/A ALA 296.A N ALA 293.A O no hydrogen 3.066 N/A GLN 297.A NE2 GLN 124.A OE1 no hydrogen 2.393 N/A TYR 298.A N PHE 295.A O no hydrogen 2.782 N/A HIS 299.A N PHE 295.A O no hydrogen 2.910 N/A ASP 300.A N GLU 304.A OE2 no hydrogen 3.181 N/A ASP 302.A N ASP 300.A OD1 no hydrogen 3.363 N/A ASP 303.A N ASP 300.A O no hydrogen 2.826 N/A ALA 307.A N SER 139.A OG no hydrogen 2.998 N/A GLN 312.A NE2 ASP 141.A O no hydrogen 3.138 N/A SER 313.A N ASP 311.A OD1 no hydrogen 2.838 N/A SER 313.A OG ASP 311.A OD1 no hydrogen 2.703 N/A GLU 315.A N GLN 312.A O no hydrogen 2.988 N/A SER 316.A N SER 313.A O no hydrogen 3.154 N/A SER 316.A OG SER 313.A O no hydrogen 3.080 N/A ARG 317.A N PHE 314.A O no hydrogen 3.113 N/A LEU 320.A N GLU 323.A OE1 no hydrogen 3.123 N/A GLU 323.A N LEU 320.A O no hydrogen 2.799 N/A TRP 324.A N LEU 320.A O no hydrogen 3.002 N/A LYS 325.A N ILE 321.A O no hydrogen 2.862 N/A LYS 325.A NZ PHE 95.A O no hydrogen 2.677 N/A SER 326.A N ASP 322.A O no hydrogen 2.984 N/A LEU 327.A N GLU 323.A O no hydrogen 2.928 N/A THR 328.A N TRP 324.A O no hydrogen 3.001 N/A THR 328.A OG1 TRP 324.A O no hydrogen 2.990 N/A TYR 329.A N LYS 325.A O no hydrogen 2.985 N/A ASP 330.A N SER 326.A O no hydrogen 2.895 N/A GLU 331.A N LEU 327.A O no hydrogen 3.147 N/A VAL 332.A N THR 328.A O no hydrogen 3.033 N/A ILE 333.A N TYR 329.A O no hydrogen 2.791 N/A SER 334.A N ASP 330.A O no hydrogen 2.971 N/A SER 334.A OG ASP 330.A O no hydrogen 2.945 N/A SER 334.A OG GLU 331.A O no hydrogen 3.389 N/A PHE 335.A N VAL 332.A O no hydrogen 3.171 N/A