Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 1lr4_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 1.A N ASP 202.A OD2 no hydrogen 2.795 N/A SER 1.A OG HIS 303.A NE2 no hydrogen 2.830 N/A SER 1.A OG GLN 304.A OE1 no hydrogen 3.030 N/A ALA 3.A N TYR 176.A OH no hydrogen 3.020 N/A ARG 4.A NH1 GLN 304.A O no hydrogen 2.936 N/A TYR 6.A OH ASP 139.A OD1 no hydrogen 2.679 N/A ASN 10.A ND2 GLY 145.A O no hydrogen 3.016 N/A ASN 10.A ND2 TYR 176.A O no hydrogen 2.775 N/A VAL 11.A N ASP 8.A O no hydrogen 3.085 N/A LEU 12.A N ASP 8.A O no hydrogen 2.942 N/A ARG 13.A N VAL 9.A O no hydrogen 3.159 N/A TYR 17.A N PRO 14.A O no hydrogen 2.712 N/A TYR 17.A OH GLN 144.A O no hydrogen 2.581 N/A ASP 19.A N LYS 15.A O no hydrogen 2.812 N/A TYR 20.A N TRP 18.A O no hydrogen 2.816 N/A TYR 20.A OH GLU 174.A OE2 no hydrogen 2.587 N/A ALA 22.A N ASP 19.A O no hydrogen 3.254 N/A LEU 23.A N TYR 20.A O no hydrogen 3.186 N/A GLY 28.A N ILE 94.A O no hydrogen 2.762 N/A ASP 32.A N GLU 29.A O no hydrogen 3.166 N/A TYR 33.A N GLN 30.A O no hydrogen 3.485 N/A TYR 33.A OH ASP 93.A OD2 no hydrogen 2.343 N/A GLU 34.A N ILE 51.A O no hydrogen 3.172 N/A VAL 36.A N GLU 49.A O no hydrogen 2.767 N/A ARG 37.A N GLU 49.A O no hydrogen 3.304 N/A ARG 37.A NE GLU 49.A OE1.A no hydrogen 2.877 N/A ARG 37.A NE GLU 49.A OE1.B no hydrogen 2.453 N/A ARG 37.A NH2 GLU 49.A OE1.A no hydrogen 2.799 N/A ARG 37.A NH2 GLU 49.A OE1.B no hydrogen 2.601 N/A LYS 38.A NZ GLU 46.A OE2 no hydrogen 2.290 N/A VAL 39.A N VAL 47.A O no hydrogen 2.816 N/A GLY 40.A N VAL 47.A O no hydrogen 3.131 N/A ARG 41.A NH1 ARG 41.A O no hydrogen 3.163 N/A GLY 42.A N SER 45.A O no hydrogen 2.873 N/A GLU 46.A N ILE 63.A O no hydrogen 3.016 N/A VAL 47.A N GLY 40.A O no hydrogen 2.953 N/A PHE 48.A N ILE 61.A O no hydrogen 2.681 N/A GLU 49.A N ARG 37.A O no hydrogen 2.767 N/A GLY 50.A N CYS 59.A O no hydrogen 2.950 N/A ILE 51.A N GLU 34.A O no hydrogen 2.871 N/A ASN 52.A N GLU 57.A O no hydrogen 2.767 N/A VAL 53.A N ASP 32.A O no hydrogen 2.938 N/A ASN 55.A ND2 ASN 52.A OD1 no hydrogen 3.299 N/A ASN 56.A N ASN 52.A O no hydrogen 2.609 N/A ASN 56.A ND2 ASN 54.A O no hydrogen 3.419 N/A GLU 57.A N ASN 55.A OD1 no hydrogen 3.214 N/A LYS 58.A NZ GLU 49.A OE2.A no hydrogen 2.956 N/A CYS 59.A N GLY 50.A O no hydrogen 3.093 N/A ILE 60.A N PHE 107.A O no hydrogen 2.813 N/A ILE 61.A N PHE 48.A O no hydrogen 2.738 N/A LYS 62.A N LEU 105.A O no hydrogen 2.935 N/A LYS 62.A NZ GLU 75.A OE2 no hydrogen 2.648 N/A LYS 62.A NZ ASP 169.A OD1 no hydrogen 3.051 N/A ILE 63.A N GLU 46.A O no hydrogen 2.825 N/A LEU 64.A N PRO 103.A O no hydrogen 3.057 N/A LYS 65.A N TYR 44.A O no hydrogen 2.919 N/A LYS 65.A NZ GLY 42.A O no hydrogen 2.704 N/A LYS 70.A NZ GLU 21.A OE2 no hydrogen 3.188 N/A LYS 71.A NZ.A GLY 171.A O no hydrogen 3.063 N/A LYS 73.A N LYS 69.A O no hydrogen 2.894 N/A LYS 73.A NZ GLU 21.A O no hydrogen 2.684 N/A LYS 73.A NZ LEU 23.A O no hydrogen 3.031 N/A ARG 74.A N LYS 70.A O no hydrogen 2.845 N/A ARG 74.A NH1 GLY 171.A O no hydrogen 3.263 N/A ARG 74.A NH2 GLU 174.A OE2 no hydrogen 3.055 N/A GLU 75.A N LYS 71.A O no hydrogen 3.204 N/A ILE 76.A N ILE 72.A O no hydrogen 3.265 N/A LYS 77.A N LYS 73.A O no hydrogen 3.092 N/A LYS 77.A NZ GLU 16.A O no hydrogen 3.153 N/A ILE 78.A N ARG 74.A O no hydrogen 3.013 N/A LEU 79.A N GLU 75.A O no hydrogen 2.935 N/A GLN 80.A N ILE 76.A O no hydrogen 2.820 N/A ASN 81.A N LYS 77.A O no hydrogen 2.883 N/A ASN 81.A ND2 TYR 17.A O no hydrogen 3.081 N/A LEU 82.A N ILE 78.A O no hydrogen 2.950 N/A CYS 83.A N GLN 80.A O no hydrogen 3.334 N/A GLY 85.A N LEU 82.A O no hydrogen 2.983 N/A ASN 87.A ND2 GLU 133.A O no hydrogen 3.057 N/A ASN 87.A ND2 GLU 133.A OE1 no hydrogen 2.888 N/A ILE 88.A N GLY 85.A O no hydrogen 3.350 N/A VAL 89.A N LEU 167.A O no hydrogen 3.395 N/A LYS 90.A N GLU 108.A OE2 no hydrogen 2.829 N/A LEU 92.A N ILE 106.A O no hydrogen 2.799 N/A ASP 93.A N ILE 106.A O no hydrogen 3.253 N/A ILE 94.A N ASP 93.A OD1 no hydrogen 2.942 N/A VAL 95.A N SER 104.A O no hydrogen 3.008 N/A ASP 97.A N THR 102.A O no hydrogen 3.064 N/A SER 100.A N ASP 97.A OD2 no hydrogen 2.536 N/A SER 100.A OG ASP 97.A OD2 no hydrogen 2.330 N/A SER 100.A OG THR 102.A OG1 no hydrogen 2.874 N/A LYS 101.A N ASP 97.A O no hydrogen 2.482 N/A THR 102.A N SER 100.A OG no hydrogen 3.153 N/A THR 102.A OG1 SER 100.A OG no hydrogen 2.874 N/A SER 104.A N VAL 95.A O no hydrogen 2.793 N/A LEU 105.A N LYS 62.A O no hydrogen 2.911 N/A ILE 106.A N ASP 93.A O no hydrogen 2.973 N/A PHE 107.A N ILE 60.A O no hydrogen 2.838 N/A GLU 108.A N LYS 90.A O no hydrogen 3.107 N/A TYR 109.A OH GLU 49.A OE2.B no hydrogen 3.326 N/A THR 113.A N ILE 158.A O no hydrogen 2.835 N/A THR 113.A OG1 ILE 158.A O no hydrogen 3.225 N/A LYS 116.A N ASP 114.A OD2 no hydrogen 3.079 N/A VAL 117.A N ASP 114.A O no hydrogen 2.921 N/A LEU 118.A N ASP 114.A O no hydrogen 2.870 N/A TYR 119.A N PHE 115.A O no hydrogen 2.959 N/A THR 121.A N LEU 118.A O no hydrogen 2.801 N/A THR 121.A OG1 LEU 118.A O no hydrogen 2.834 N/A LEU 122.A N TYR 119.A O no hydrogen 3.093 N/A THR 123.A N ASP 126.A OD2 no hydrogen 2.738 N/A THR 123.A OG1 ASP 126.A OD2 no hydrogen 3.159 N/A ASP 126.A N THR 123.A OG1 no hydrogen 3.398 N/A ILE 127.A N THR 123.A O no hydrogen 3.115 N/A ARG 128.A N ASP 124.A O no hydrogen 3.316 N/A ARG 128.A NE ASP 124.A OD1 no hydrogen 2.933 N/A ARG 128.A NE ASP 124.A OD2 no hydrogen 3.405 N/A ARG 128.A NH1 TYR 317.A O no hydrogen 2.965 N/A ARG 128.A NH2 ASP 124.A OD1 no hydrogen 3.020 N/A ARG 128.A NH2 ASP 124.A OD2 no hydrogen 3.504 N/A TYR 129.A N TYR 125.A O no hydrogen 2.948 N/A TYR 129.A OH ARG 163.A O no hydrogen 2.928 N/A TYR 130.A N ASP 126.A O no hydrogen 2.988 N/A TYR 130.A OH HIS 160.A ND1 no hydrogen 2.741 N/A ILE 131.A N ILE 127.A O no hydrogen 2.815 N/A TYR 132.A N ARG 128.A O no hydrogen 2.944 N/A GLU 133.A N TYR 129.A O no hydrogen 3.072 N/A LEU 134.A N TYR 130.A O no hydrogen 2.987 N/A LEU 135.A N ILE 131.A O no hydrogen 2.876 N/A LYS 136.A N TYR 132.A O no hydrogen 3.150 N/A LYS 136.A NZ GLU 133.A OE2 no hydrogen 2.702 N/A LYS 136.A NZ GLU 325.A OE1 no hydrogen 2.685 N/A LEU 138.A N LEU 134.A O no hydrogen 3.137 N/A ASP 139.A N LEU 135.A O no hydrogen 2.913 N/A TYR 140.A N LYS 136.A O no hydrogen 3.010 N/A CYS 141.A N ALA 137.A O no hydrogen 2.878 N/A CYS 141.A SG ALA 137.A O no hydrogen 3.761 N/A CYS 141.A SG LEU 138.A O no hydrogen 3.501 N/A CYS 141.A SG HIS 142.A ND1 no hydrogen 3.761 N/A CYS 141.A SG ILE 146.A O no hydrogen 3.836 N/A HIS 142.A N LEU 138.A O no hydrogen 3.013 N/A HIS 142.A ND1 ILE 146.A O no hydrogen 3.312 N/A SER 143.A N ASP 139.A O no hydrogen 3.012 N/A SER 143.A OG ASP 139.A O no hydrogen 3.255 N/A SER 143.A OG TYR 140.A O no hydrogen 2.599 N/A SER 143.A OG GLN 144.A OE1 no hydrogen 3.182 N/A GLN 144.A N CYS 141.A O no hydrogen 2.957 N/A GLY 145.A N HIS 142.A O no hydrogen 2.919 N/A ILE 146.A N CYS 141.A O no hydrogen 2.984 N/A MET 147.A N GLU 174.A O no hydrogen 2.900 N/A HIS 148.A N ASP 208.A OD2 no hydrogen 2.868 N/A HIS 148.A NE2 ILE 168.A O no hydrogen 3.018 N/A ARG 149.A N ASP 208.A OD1 no hydrogen 2.807 N/A ARG 149.A NE LEU 172.A O no hydrogen 2.654 N/A ARG 149.A NH1 LEU 172.A O no hydrogen 2.829 N/A ARG 149.A NH2 TYR 203.A OH no hydrogen 2.876 N/A ASP 150.A N HIS 148.A ND1 no hydrogen 3.066 N/A LYS 152.A NZ SER 188.A OG.B no hydrogen 2.708 N/A HIS 154.A N HIS 154.A ND1.B no hydrogen 2.360 N/A ASN 155.A N LYS 152.A O no hydrogen 2.746 N/A ASN 155.A ND2 ASP 150.A O no hydrogen 2.790 N/A ASN 155.A ND2 ASP 150.A OD2 no hydrogen 3.210 N/A VAL 156.A N PRO 153.A O no hydrogen 3.024 N/A MET 157.A N ARG 166.A O no hydrogen 2.771 N/A ILE 158.A N ASN 112.A OD1 no hydrogen 3.331 N/A ASP 159.A N LYS 164.A O no hydrogen 3.025 N/A HIS 160.A ND1 TYR 130.A OH no hydrogen 2.741 N/A LEU 162.A N ASP 159.A OD1 no hydrogen 3.046 N/A ARG 163.A NH1 ASP 126.A OD1 no hydrogen 2.355 N/A ARG 163.A NH2 ASP 126.A OD1 no hydrogen 2.804 N/A LYS 164.A N ASP 159.A O no hydrogen 3.322 N/A ARG 166.A N MET 157.A O no hydrogen 2.820 N/A ARG 166.A NE GLU 108.A OE2 no hydrogen 3.347 N/A ARG 166.A NH1 LEU 165.A O no hydrogen 2.883 N/A LEU 167.A N ASN 87.A O no hydrogen 2.868 N/A ILE 168.A N ASN 155.A O no hydrogen 2.958 N/A TRP 170.A NE1 LEU 167.A O no hydrogen 2.984 N/A GLY 171.A N ASP 169.A OD1 no hydrogen 3.316 N/A ALA 173.A N TRP 170.A O no hydrogen 3.344 N/A GLU 174.A N MET 147.A O no hydrogen 3.173 N/A PHE 175.A N GLU 174.A OE1 no hydrogen 2.735 N/A TYR 176.A N GLY 145.A O no hydrogen 2.916 N/A HIS 177.A N TYR 182.A OH no hydrogen 3.012 N/A LYS 180.A N HIS 177.A O no hydrogen 3.071 N/A TYR 182.A N GLN 201.A O no hydrogen 2.818 N/A TYR 182.A OH PHE 175.A O no hydrogen 2.693 N/A ARG 185.A N ASN 183.A OD1 no hydrogen 2.857 N/A SER 188.A OG.B ASP 150.A OD1 no hydrogen 3.051 N/A PHE 191.A N SER 188.A O no hydrogen 2.911 N/A LYS 192.A N ARG 189.A O no hydrogen 3.218 N/A LYS 192.A NZ VAL 186.A O no hydrogen 2.710 N/A GLU 195.A N GLU 195.A OE1 no hydrogen 2.854 N/A LEU 196.A N GLY 193.A O no hydrogen 2.844 N/A LEU 197.A N GLY 193.A O no hydrogen 3.203 N/A VAL 198.A N PRO 194.A O no hydrogen 2.825 N/A LEU 200.A N GLU 195.A O no hydrogen 2.852 N/A GLN 201.A NE2 TYR 182.A O no hydrogen 3.105 N/A TYR 203.A OH ASN 183.A O no hydrogen 2.525 N/A TYR 205.A OH TYR 6.A O no hydrogen 2.874 N/A SER 206.A N ASP 204.A OD1 no hydrogen 2.903 N/A SER 206.A OG ASP 204.A OD1 no hydrogen 2.650 N/A LEU 207.A N ASP 204.A O no hydrogen 2.919 N/A ASP 208.A N TYR 205.A O no hydrogen 3.230 N/A MET 209.A N SER 206.A O no hydrogen 3.022 N/A TRP 210.A N SER 206.A O no hydrogen 3.259 N/A SER 211.A N LEU 207.A O no hydrogen 3.188 N/A SER 211.A OG PHE 191.A O no hydrogen 2.817 N/A SER 211.A OG LEU 207.A O no hydrogen 3.452 N/A LEU 212.A N ASP 208.A O no hydrogen 2.888 N/A GLY 213.A N MET 209.A O no hydrogen 2.934 N/A CYS 214.A N TRP 210.A O no hydrogen 2.999 N/A CYS 214.A SG TYR 190.A O no hydrogen 3.854 N/A CYS 214.A SG TRP 210.A O no hydrogen 3.461 N/A MET 215.A N SER 211.A O no hydrogen 3.068 N/A PHE 216.A N LEU 212.A O no hydrogen 2.869 N/A ALA 217.A N GLY 213.A O no hydrogen 2.898 N/A GLY 218.A N CYS 214.A O no hydrogen 3.034 N/A MET 219.A N MET 215.A O no hydrogen 2.995 N/A ILE 220.A N PHE 216.A O no hydrogen 3.035 N/A PHE 221.A N ALA 217.A O no hydrogen 2.958 N/A ARG 222.A NH1 ASP 282.A OD1 no hydrogen 2.643 N/A LYS 223.A N GLY 218.A O no hydrogen 3.183 N/A LYS 223.A NZ PHE 226.A O no hydrogen 3.337 N/A GLY 229.A N GLN 235.A OE1 no hydrogen 3.092 N/A HIS 230.A N ASP 234.A OD2 no hydrogen 3.019 N/A ASP 234.A N ASP 231.A OD1 no hydrogen 2.805 N/A GLN 235.A N ASP 231.A O no hydrogen 2.887 N/A GLN 235.A NE2 PHE 227.A O no hydrogen 3.175 N/A LEU 236.A N ASN 232.A O no hydrogen 3.405 N/A VAL 237.A N HIS 233.A O no hydrogen 3.266 N/A LYS 238.A N ASP 234.A O no hydrogen 2.843 N/A ILE 239.A N GLN 235.A O no hydrogen 3.094 N/A ALA 240.A N LEU 236.A O no hydrogen 2.960 N/A LYS 241.A N VAL 237.A O no hydrogen 2.949 N/A VAL 242.A N ILE 239.A O no hydrogen 2.873 N/A LEU 243.A N ILE 239.A O no hydrogen 2.823 N/A GLY 244.A N ALA 240.A O no hydrogen 2.878 N/A THR 245.A N HIS 270.A O no hydrogen 2.941 N/A THR 245.A OG1 HIS 270.A O no hydrogen 3.023 N/A ASN 249.A N THR 245.A O no hydrogen 3.082 N/A VAL 250.A N ASP 246.A O no hydrogen 3.053 N/A TYR 251.A N GLY 247.A O no hydrogen 3.054 N/A LEU 252.A N LEU 248.A O no hydrogen 2.894 N/A ASN 253.A N ASN 249.A O no hydrogen 3.213 N/A LYS 254.A N VAL 250.A O no hydrogen 3.096 N/A LYS 254.A NZ ASP 302.A OD2 no hydrogen 2.609 N/A TYR 255.A N TYR 251.A O no hydrogen 3.119 N/A TYR 255.A OH ASP 302.A OD1 no hydrogen 2.403 N/A TYR 255.A OH ASP 302.A OD2 no hydrogen 3.105 N/A ARG 256.A N ASN 253.A O no hydrogen 3.239 N/A ILE 257.A N LEU 252.A O no hydrogen 2.792 N/A GLN 262.A N ASP 260.A OD1 no hydrogen 2.704 N/A GLU 264.A N ASP 260.A O no hydrogen 2.794 N/A ALA 265.A N PRO 261.A O no hydrogen 2.989 N/A LEU 266.A N GLN 262.A O no hydrogen 2.910 N/A VAL 267.A N LEU 263.A O no hydrogen 2.816 N/A GLY 268.A N GLU 264.A O no hydrogen 3.170 N/A HIS 270.A N THR 245.A OG1 no hydrogen 2.857 N/A ARG 272.A NH2 ASP 296.A OD1 no hydrogen 3.069 N/A LYS 273.A N VAL 242.A O no hydrogen 2.896 N/A LYS 273.A NZ LYS 241.A O no hydrogen 2.865 N/A LYS 273.A NZ SER 271.A O no hydrogen 2.574 N/A TRP 275.A NE1 ASP 296.A OD1 no hydrogen 2.886 N/A LYS 277.A N PRO 274.A O no hydrogen 3.027 N/A PHE 278.A N TRP 275.A O no hydrogen 3.283 N/A MET 279.A N LEU 276.A O no hydrogen 2.921 N/A ASN 280.A N ASN 283.A OD1 no hydrogen 2.786 N/A ASP 282.A N ASN 280.A OD1 no hydrogen 2.752 N/A ASN 283.A N ASN 280.A O no hydrogen 2.802 N/A ASN 283.A N ASN 280.A OD1 no hydrogen 3.122 N/A ASN 283.A ND2 PHE 221.A O no hydrogen 3.090 N/A ASN 283.A ND2 PHE 278.A O no hydrogen 3.056 N/A GLN 284.A N ASN 280.A O no hydrogen 2.936 N/A LEU 286.A N ASN 283.A O no hydrogen 2.474 N/A VAL 287.A N GLN 284.A O no hydrogen 3.346 N/A ILE 292.A N SER 288.A O no hydrogen 3.129 N/A ASP 293.A N PRO 289.A O no hydrogen 2.967 N/A PHE 294.A N GLU 290.A O no hydrogen 3.122 N/A LEU 295.A N ALA 291.A O no hydrogen 3.023 N/A ASP 296.A N ILE 292.A O no hydrogen 2.890 N/A LYS 297.A N ASP 293.A O no hydrogen 3.275 N/A LYS 297.A N PHE 294.A O no hydrogen 3.034 N/A LYS 297.A NZ ASP 293.A OD2 no hydrogen 2.776 N/A LEU 298.A N LEU 295.A O no hydrogen 2.982 N/A LEU 299.A N LEU 295.A O no hydrogen 2.972 N/A ARG 300.A N LEU 298.A O no hydrogen 3.086 N/A ARG 300.A NE ASP 296.A O no hydrogen 3.106 N/A ARG 300.A NH1 GLU 305.A OE1 no hydrogen 3.497 N/A TYR 301.A OH GLY 244.A O no hydrogen 2.596 N/A HIS 303.A NE2 SER 1.A OG no hydrogen 2.830 N/A GLN 304.A N ASP 302.A OD1 no hydrogen 2.933 N/A GLU 305.A N ASP 302.A O no hydrogen 2.962 N/A ARG 306.A N HIS 303.A O no hydrogen 3.386 N/A ARG 306.A NE ARG 300.A O no hydrogen 2.918 N/A ARG 306.A NH1 GLU 195.A OE1 no hydrogen 3.377 N/A ARG 306.A NH1 GLU 195.A OE2 no hydrogen 2.949 N/A ARG 306.A NH1 SER 206.A O no hydrogen 3.059 N/A ARG 306.A NH2 GLU 195.A OE1 no hydrogen 2.920 N/A ARG 306.A NH2 ARG 300.A O no hydrogen 3.238 N/A LEU 307.A N LYS 297.A O no hydrogen 3.038 N/A THR 308.A N GLU 311.A OE1 no hydrogen 2.966 N/A THR 308.A OG1 GLU 311.A OE1 no hydrogen 3.105 N/A GLU 311.A N THR 308.A OG1 no hydrogen 3.216 N/A ALA 312.A N THR 308.A O no hydrogen 2.834 N/A MET 313.A N ALA 309.A O no hydrogen 3.232 N/A THR 314.A N GLU 311.A O no hydrogen 2.965 N/A THR 314.A OG1 GLU 311.A O no hydrogen 3.173 N/A HIS 315.A N ALA 312.A O no hydrogen 3.100 N/A HIS 315.A NE2 ASP 293.A OD2 no hydrogen 2.724 N/A TYR 317.A N HIS 315.A ND1 no hydrogen 2.914 N/A PHE 318.A N HIS 315.A O no hydrogen 2.899 N/A GLN 319.A N PRO 316.A O no hydrogen 2.960 N/A ARG 322.A N PHE 318.A O no hydrogen 2.968 N/A ARG 322.A NH1 MET 313.A O no hydrogen 2.953 N/A ARG 322.A NH1 HIS 315.A O no hydrogen 2.784 N/A ALA 323.A N GLN 319.A O no hydrogen 2.774 N/A ALA 324.A N GLN 320.A O no hydrogen 2.820 N/A GLU 325.A N VAL 321.A O no hydrogen 3.080 N/A ASN 326.A N ARG 322.A O no hydrogen 3.036 N/A ASN 326.A N ALA 323.A O no hydrogen 3.128 N/A SER 327.A N ALA 324.A O no hydrogen 3.359 N/A