Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 1nx8_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASN 7.A N TYR 17.A O no hydrogen 3.087 N/A VAL 9.A N PHE 14.A O no hydrogen 2.993 N/A MET 10.A N PHE 14.A O no hydrogen 2.947 N/A GLY 13.A N MET 10.A O no hydrogen 2.925 N/A PHE 14.A N SER 12.A OG no hydrogen 3.295 N/A GLY 15.A N GLN 38.A O no hydrogen 2.912 N/A ALA 16.A N PHE 40.A O no hydrogen 3.004 N/A TYR 17.A N ASN 7.A O no hydrogen 2.722 N/A ILE 18.A N VAL 42.A O no hydrogen 2.894 N/A ARG 21.A N ASP 19.A OD1 no hydrogen 2.983 N/A PHE 23.A N ASP 19.A O no hydrogen 2.866 N/A LEU 24.A N HIS 20.A O no hydrogen 3.136 N/A GLU 25.A N ARG 21.A O no hydrogen 2.996 N/A ALA 26.A N ASP 22.A O no hydrogen 3.199 N/A ALA 26.A N PHE 23.A O no hydrogen 3.338 N/A LYS 27.A NZ GLU 2.A OE2 no hydrogen 2.912 N/A THR 30.A N LYS 27.A O no hydrogen 3.177 N/A ILE 31.A N THR 28.A O no hydrogen 3.089 N/A LYS 32.A N THR 28.A O no hydrogen 2.940 N/A LYS 32.A NZ TYR 60.A O no hydrogen 2.845 N/A LYS 32.A NZ ASP 248.A OD2 no hydrogen 2.804 N/A ASN 33.A N GLU 29.A O no hydrogen 2.875 N/A LEU 34.A N THR 30.A O no hydrogen 3.125 N/A LEU 35.A N ILE 31.A O no hydrogen 2.824 N/A MET 36.A N ASN 33.A O no hydrogen 3.179 N/A ARG 37.A N LEU 34.A O no hydrogen 3.233 N/A GLN 38.A N LEU 34.A O no hydrogen 2.906 N/A GLN 38.A NE2 GLY 13.A O no hydrogen 2.879 N/A GLN 38.A NE2 GLY 15.A O no hydrogen 2.872 N/A GLY 39.A N LEU 35.A O no hydrogen 2.815 N/A PHE 40.A N GLN 38.A O no hydrogen 2.912 N/A VAL 41.A N ILE 219.A O no hydrogen 2.930 N/A VAL 42.A N ALA 16.A O no hydrogen 2.837 N/A VAL 43.A N LEU 217.A O no hydrogen 2.890 N/A LYS 44.A NZ GLU 213.A OE1 no hydrogen 2.984 N/A LYS 44.A NZ ASP 216.A OD1 no hydrogen 2.926 N/A LYS 44.A NZ ASP 216.A OD2 no hydrogen 3.148 N/A LEU 46.A N GLY 215.A O no hydrogen 3.227 N/A ILE 48.A N TYR 105.A OH no hydrogen 3.147 N/A THR 52.A N ASP 49.A OD1 no hydrogen 3.326 N/A THR 52.A OG1 ASP 49.A OD1 no hydrogen 2.906 N/A PHE 53.A N ASP 49.A O no hydrogen 3.009 N/A ARG 54.A N SER 50.A O no hydrogen 2.947 N/A ARG 54.A NH1 ASP 68.A OD2 no hydrogen 2.852 N/A ASP 55.A N ASP 51.A O no hydrogen 2.967 N/A ILE 56.A N THR 52.A O no hydrogen 2.910 N/A TYR 57.A N PHE 53.A O no hydrogen 2.979 N/A TYR 57.A OH THR 69.A OG1 no hydrogen 2.762 N/A SER 58.A N ARG 54.A O no hydrogen 2.944 N/A SER 58.A OG ARG 54.A O no hydrogen 2.789 N/A SER 58.A OG ASP 55.A O no hydrogen 3.507 N/A TYR 60.A N TYR 57.A O no hydrogen 3.040 N/A THR 62.A N ALA 247.A O no hydrogen 2.934 N/A THR 62.A OG1 ALA 247.A O no hydrogen 3.520 N/A VAL 64.A N GLN 245.A O no hydrogen 2.830 N/A TYR 66.A N ARG 67.A O no hydrogen 3.298 N/A TYR 66.A OH THR 69.A O no hydrogen 3.381 N/A ASP 68.A N ASP 68.A OD1 no hydrogen 2.385 N/A THR 69.A OG1 TYR 57.A OH no hydrogen 2.762 N/A LEU 70.A N ARG 243.A O no hydrogen 2.874 N/A LEU 72.A N LEU 241.A O no hydrogen 2.842 N/A GLU 75.A N THR 81.A O no hydrogen 2.829 N/A GLY 82.A N ILE 79.A O no hydrogen 2.997 N/A ARG 83.A NH1 GLY 74.A O no hydrogen 3.062 N/A ARG 83.A NH2 ASP 234.A O no hydrogen 2.819 N/A ARG 83.A NH2 ILE 237.A O no hydrogen 2.764 N/A GLN 85.A N GLN 174.A OE1 no hydrogen 2.889 N/A LEU 86.A N ARG 229.A O no hydrogen 2.771 N/A HIS 89.A N HIS 227.A O no hydrogen 2.859 N/A HIS 89.A ND1 PRO 87.A O no hydrogen 2.900 N/A ASP 91.A N ASN 222.A OD1 no hydrogen 2.798 N/A GLY 93.A N TYR 167.A OH no hydrogen 2.825 N/A SER 97.A N LEU 95.A O no hydrogen 2.995 N/A GLN 98.A NE2 ASP 100.A OD1 no hydrogen 3.121 N/A ASP 100.A N THR 246.A O no hydrogen 2.814 N/A GLN 101.A N THR 246.A O no hydrogen 2.931 N/A VAL 102.A N MET 220.A O no hydrogen 2.839 N/A PHE 103.A N GLY 244.A O no hydrogen 2.788 N/A LEU 104.A N LEU 218.A O no hydrogen 2.695 N/A TYR 105.A N TYR 242.A O no hydrogen 3.033 N/A TYR 105.A OH ILE 48.A O no hydrogen 3.319 N/A ALA 106.A N ASP 216.A O no hydrogen 2.889 N/A ALA 107.A N ARG 240.A O no hydrogen 3.093 N/A GLU 108.A N ARG 240.A O no hydrogen 3.437 N/A ILE 109.A N ASP 214.A OD1 no hydrogen 2.750 N/A LYS 110.A N VAL 238.A O no hydrogen 2.897 N/A LYS 110.A NZ GLU 108.A OE2 no hydrogen 2.800 N/A ASN 111.A ND2 ASP 236.A O no hydrogen 2.887 N/A ARG 115.A NE GLU 231.A OE2 no hydrogen 2.864 N/A ARG 115.A NH2 GLU 231.A OE1 no hydrogen 3.200 N/A ARG 115.A NH2 GLU 231.A OE2 no hydrogen 3.450 N/A GLY 116.A N GLU 231.A O no hydrogen 2.898 N/A THR 118.A N HIS 210.A O no hydrogen 3.168 N/A THR 119.A N GLU 228.A O no hydrogen 2.731 N/A THR 119.A OG1 GLU 228.A O no hydrogen 3.351 N/A THR 119.A OG1 GLU 228.A OE1 no hydrogen 2.822 N/A VAL 120.A N TYR 208.A O no hydrogen 2.836 N/A CYS 121.A N ILE 226.A O no hydrogen 2.952 N/A CYS 121.A SG LEU 201.A O no hydrogen 3.728 N/A CYS 121.A SG TYR 206.A O no hydrogen 4.018 N/A ASP 122.A N TYR 206.A O no hydrogen 2.812 N/A LEU 125.A N ASP 122.A OD1 no hydrogen 3.399 N/A ALA 126.A N ASP 122.A O no hydrogen 3.208 N/A CYS 127.A N HIS 123.A O no hydrogen 2.971 N/A CYS 127.A SG HIS 123.A O no hydrogen 3.244 N/A GLN 128.A N ALA 124.A O no hydrogen 3.136 N/A GLU 129.A N LEU 125.A O no hydrogen 3.045 N/A GLU 129.A N ALA 126.A O no hydrogen 3.222 N/A MET 130.A N ALA 126.A O no hydrogen 2.829 N/A HIS 133.A NE2 GLU 196.A OE2 no hydrogen 2.849 N/A LEU 134.A N PRO 131.A O no hydrogen 2.982 N/A LEU 135.A N PRO 131.A O no hydrogen 3.333 N/A ARG 136.A N ALA 132.A O no hydrogen 3.097 N/A ARG 136.A NH2 GLU 141.A OE1 no hydrogen 2.872 N/A LEU 138.A N LEU 134.A O no hydrogen 3.489 N/A GLU 139.A N LEU 135.A O no hydrogen 2.895 N/A GLU 140.A N ARG 136.A O no hydrogen 2.947 N/A GLU 141.A N VAL 137.A O no hydrogen 3.113 N/A GLU 144.A N ARG 181.A O no hydrogen 2.796 N/A VAL 145.A N PHE 150.A O no hydrogen 3.004 N/A ARG 146.A N GLU 179.A O no hydrogen 2.869 N/A ARG 146.A NE GLU 179.A OE2 no hydrogen 2.933 N/A ARG 146.A NH2 GLU 179.A OE2 no hydrogen 2.745 N/A LEU 148.A N SER 177.A O no hydrogen 2.888 N/A PHE 150.A N VAL 145.A O no hydrogen 3.199 N/A VAL 152.A N PHE 143.A O no hydrogen 3.078 N/A THR 156.A N LYS 163.A O no hydrogen 3.078 N/A LEU 158.A N VAL 161.A O no hydrogen 2.908 N/A GLY 159.A N ASP 157.A OD1 no hydrogen 3.071 N/A ARG 162.A NH1 GLU 139.A OE2 no hydrogen 2.910 N/A ARG 162.A NH2 GLU 139.A OE2 no hydrogen 2.888 N/A LYS 163.A N THR 156.A O no hydrogen 2.921 N/A LEU 165.A N VAL 154.A O no hydrogen 3.012 N/A PHE 168.A N PHE 88.A O no hydrogen 2.964 N/A ASP 171.A N GLN 85.A OE1 no hydrogen 2.968 N/A GLN 174.A N ASP 171.A O no hydrogen 3.066 N/A TRP 178.A NE1 PHE 168.A O no hydrogen 2.877 N/A GLU 179.A N ARG 146.A O no hydrogen 3.029 N/A ARG 181.A N GLU 144.A O no hydrogen 2.842 N/A ARG 181.A NH1 GLU 144.A OE1 no hydrogen 2.939 N/A VAL 183.A N THR 142.A O no hydrogen 2.893 N/A PHE 185.A N ILE 182.A O no hydrogen 3.221 N/A THR 186.A N GLU 189.A OE1 no hydrogen 2.897 N/A THR 186.A OG1 GLU 189.A OE1 no hydrogen 3.442 N/A THR 190.A N THR 186.A O no hydrogen 3.001 N/A THR 190.A OG1 THR 186.A O no hydrogen 3.533 N/A GLN 191.A N ASP 187.A O no hydrogen 3.398 N/A ALA 192.A N HIS 188.A O no hydrogen 3.028 N/A PHE 193.A N GLU 189.A O no hydrogen 2.874 N/A PHE 194.A N THR 190.A O no hydrogen 3.053 N/A GLN 195.A N GLN 191.A O no hydrogen 3.054 N/A GLU 196.A N ALA 192.A O no hydrogen 3.217 N/A LEU 197.A N PHE 193.A O no hydrogen 2.886 N/A GLY 198.A N PHE 194.A O no hydrogen 2.758 N/A ALA 199.A N GLN 195.A O no hydrogen 3.172 N/A PHE 200.A N GLU 196.A O no hydrogen 3.168 N/A LEU 201.A N LEU 197.A O no hydrogen 2.917 N/A LYS 202.A N GLY 198.A O no hydrogen 2.995 N/A LYS 202.A NZ GLU 228.A OE2 no hydrogen 2.891 N/A GLN 203.A N PHE 200.A O no hydrogen 3.330 N/A GLN 203.A NE2 PHE 200.A O no hydrogen 2.966 N/A ARG 205.A NH1 GLU 129.A OE1 no hydrogen 3.245 N/A TYR 206.A N GLN 203.A O no hydrogen 2.852 N/A TYR 206.A OH GLU 129.A OE1 no hydrogen 2.700 N/A TYR 207.A OH GLU 228.A OE1 no hydrogen 2.657 N/A TYR 208.A N VAL 120.A O no hydrogen 2.969 N/A TYR 208.A OH HIS 210.A ND1 no hydrogen 2.765 N/A LYS 209.A NZ GLU 230.A OE1 no hydrogen 3.058 N/A HIS 210.A N THR 118.A O no hydrogen 2.892 N/A HIS 210.A ND1 TYR 208.A OH no hydrogen 2.765 N/A HIS 210.A NE2 ASP 216.A OD2 no hydrogen 2.802 N/A TRP 212.A NE1 THR 118.A OG1 no hydrogen 2.787 N/A GLU 213.A N ASP 216.A OD2 no hydrogen 2.948 N/A GLY 215.A N ALA 106.A O no hydrogen 2.915 N/A ASP 216.A N GLU 213.A O no hydrogen 3.058 N/A LEU 217.A N VAL 43.A O no hydrogen 2.811 N/A LEU 218.A N LEU 104.A O no hydrogen 2.831 N/A ILE 219.A N VAL 41.A O no hydrogen 2.975 N/A MET 220.A N VAL 102.A O no hydrogen 2.751 N/A ASP 221.A N GLY 39.A O no hydrogen 2.828 N/A ASN 222.A N ASP 100.A O no hydrogen 2.815 N/A ASN 222.A ND2 ASP 91.A O no hydrogen 2.928 N/A ASN 222.A ND2 VAL 99.A O no hydrogen 2.760 N/A ARG 223.A N ASP 221.A OD1 no hydrogen 3.089 N/A ARG 223.A NH1 ASP 221.A OD2 no hydrogen 3.068 N/A ARG 224.A N ASP 221.A O no hydrogen 3.157 N/A ARG 224.A NH1 ASP 122.A OD1 no hydrogen 2.850 N/A ARG 224.A NH1 ARG 224.A O no hydrogen 2.994 N/A ARG 224.A NH2 ASP 122.A OD1 no hydrogen 3.088 N/A VAL 225.A N ASP 221.A O no hydrogen 3.181 N/A ILE 226.A N CYS 121.A O no hydrogen 3.414 N/A HIS 227.A N HIS 89.A O no hydrogen 2.740 N/A GLU 228.A N THR 119.A O no hydrogen 3.146 N/A ARG 229.A N LEU 86.A O no hydrogen 2.832 N/A ARG 229.A NE GLY 84.A O no hydrogen 3.043 N/A ARG 229.A NH1 VAL 80.A O no hydrogen 2.895 N/A ARG 229.A NH2 VAL 80.A O no hydrogen 3.018 N/A ARG 229.A NH2 GLY 84.A O no hydrogen 3.523 N/A GLU 230.A N ALA 117.A O no hydrogen 2.852 N/A PHE 232.A N ARG 83.A O no hydrogen 2.878 N/A ASN 233.A N GLU 231.A OE1 no hydrogen 3.190 N/A ASP 234.A N PHE 232.A O no hydrogen 2.853 N/A ASP 236.A N ASP 234.A OD1 no hydrogen 3.150 N/A ILE 237.A N ASP 234.A O no hydrogen 3.216 N/A VAL 238.A N LYS 110.A O no hydrogen 2.990 N/A ARG 239.A NE GLY 116.A O no hydrogen 2.804 N/A ARG 239.A NH2 GLY 116.A O no hydrogen 2.854 N/A ARG 240.A N GLU 108.A O no hydrogen 2.906 N/A ARG 240.A NE GLU 73.A OE1 no hydrogen 2.919 N/A ARG 240.A NH1 GLU 108.A OE1 no hydrogen 2.774 N/A LEU 241.A N LEU 72.A O no hydrogen 2.742 N/A TYR 242.A N TYR 105.A O no hydrogen 2.854 N/A ARG 243.A N LEU 70.A O no hydrogen 2.751 N/A GLY 244.A N PHE 103.A O no hydrogen 3.042 N/A GLN 245.A NE2 ASP 91.A OD2 no hydrogen 3.060 N/A THR 246.A N GLN 101.A O no hydrogen 2.913 N/A THR 246.A OG1 GLN 101.A OE1 no hydrogen 2.836 N/A ALA 247.A N THR 62.A O no hydrogen 3.035 N/A ASP 248.A N ASP 100.A OD2 no hydrogen 2.876 N/A