Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 1p5e_B.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): TYR 4.A N VAL 1.A O no hydrogen 3.098 N/A HIS 5.A N PRO 2.A O no hydrogen 3.436 N/A ILE 8.A N TYR 4.A O no hydrogen 2.982 N/A HIS 9.A N HIS 5.A O no hydrogen 3.064 N/A THR 10.A N GLU 6.A O no hydrogen 2.992 N/A THR 10.A OG1 GLU 6.A O no hydrogen 3.067 N/A TYR 11.A N ASP 7.A O no hydrogen 2.860 N/A LEU 12.A N ILE 8.A O no hydrogen 2.807 N/A ARG 13.A N HIS 9.A O no hydrogen 2.934 N/A ARG 13.A NH1 THR 206.A O no hydrogen 3.039 N/A GLU 14.A N THR 10.A O no hydrogen 3.141 N/A MET 15.A N TYR 11.A O no hydrogen 2.940 N/A GLU 16.A N LEU 12.A O no hydrogen 2.910 N/A LYS 18.A N GLU 14.A O no hydrogen 3.439 N/A LYS 18.A NZ GLU 14.A OE2 no hydrogen 3.030 N/A CYS 19.A N MET 15.A O no hydrogen 2.790 N/A LYS 20.A NZ LYS 175.A O no hydrogen 3.261 N/A LYS 22.A N SER 70.A OG no hydrogen 3.062 N/A TYR 25.A N LYS 22.A O no hydrogen 3.325 N/A TYR 25.A OH ASP 66.A OD1 no hydrogen 2.733 N/A LYS 27.A N GLY 24.A O no hydrogen 3.132 N/A LYS 28.A N TYR 25.A O no hydrogen 2.867 N/A GLN 29.A N MET 26.A O no hydrogen 3.041 N/A GLN 29.A NE2 LEU 69.A O no hydrogen 2.804 N/A GLN 29.A NE2 MET 72.A O no hydrogen 2.796 N/A MET 36.A N THR 33.A OG1 no hydrogen 3.263 N/A ARG 37.A N THR 33.A O no hydrogen 3.054 N/A ARG 37.A NE ASP 66.A OD1 no hydrogen 2.669 N/A ARG 37.A NH1 LEU 167.A O no hydrogen 2.715 N/A ARG 37.A NH2 ASP 66.A OD1 no hydrogen 3.397 N/A ARG 37.A NH2 ASP 66.A OD2 no hydrogen 2.579 N/A ARG 37.A NH2 LEU 167.A O no hydrogen 3.164 N/A ALA 38.A N ASN 34.A O no hydrogen 2.821 N/A ILE 39.A N SER 35.A O no hydrogen 3.054 N/A LEU 40.A N MET 36.A O no hydrogen 3.034 N/A VAL 41.A N ARG 37.A O no hydrogen 2.927 N/A ASP 42.A N ALA 38.A O no hydrogen 2.979 N/A TRP 43.A N ILE 39.A O no hydrogen 2.985 N/A LEU 44.A N LEU 40.A O no hydrogen 2.900 N/A VAL 45.A N VAL 41.A O no hydrogen 2.921 N/A GLU 46.A N ASP 42.A O no hydrogen 3.300 N/A VAL 47.A N TRP 43.A O no hydrogen 2.862 N/A GLY 48.A N LEU 44.A O no hydrogen 2.882 N/A GLU 49.A N VAL 45.A O no hydrogen 2.999 N/A GLU 50.A N GLU 46.A O no hydrogen 2.729 N/A TYR 51.A N VAL 47.A O no hydrogen 2.979 N/A LYS 52.A N GLU 49.A O no hydrogen 3.351 N/A LEU 53.A N GLY 48.A O no hydrogen 2.742 N/A GLN 54.A N GLU 95.A OE2 no hydrogen 2.690 N/A THR 57.A OG1 GLU 95.A OE2 no hydrogen 2.555 N/A HIS 59.A N ASN 55.A O no hydrogen 2.994 N/A HIS 59.A ND1 ASN 55.A O no hydrogen 3.120 N/A LEU 60.A N GLU 56.A O no hydrogen 2.903 N/A ALA 61.A N THR 57.A O no hydrogen 3.017 N/A VAL 62.A N LEU 58.A O no hydrogen 3.086 N/A ASN 63.A N HIS 59.A O no hydrogen 3.055 N/A ASN 63.A ND2 CYS 19.A O no hydrogen 3.164 N/A TYR 64.A N LEU 60.A O no hydrogen 2.824 N/A TYR 64.A OH LEU 132.A O no hydrogen 2.667 N/A ILE 65.A N ALA 61.A O no hydrogen 2.956 N/A ASP 66.A N VAL 62.A O no hydrogen 2.953 N/A ARG 67.A N ASN 63.A O no hydrogen 3.111 N/A ARG 67.A NH1 ASN 63.A OD1 no hydrogen 2.891 N/A ARG 67.A NH1 ASP 131.A O no hydrogen 2.900 N/A ARG 67.A NH2 ASP 131.A O no hydrogen 2.764 N/A PHE 68.A N TYR 64.A O no hydrogen 2.910 N/A LEU 69.A N ILE 65.A O no hydrogen 2.861 N/A SER 70.A N ARG 67.A O no hydrogen 3.097 N/A SER 70.A OG ASP 66.A O no hydrogen 2.644 N/A SER 71.A N PHE 68.A O no hydrogen 3.165 N/A SER 71.A OG ARG 67.A O no hydrogen 3.377 N/A MET 72.A N PHE 68.A O no hydrogen 2.891 N/A VAL 74.A N GLN 29.A OE1 no hydrogen 3.022 N/A ARG 76.A N ASP 31.A OD2 no hydrogen 2.846 N/A ARG 76.A NE ASP 31.A OD1 no hydrogen 3.072 N/A ARG 76.A NE ASP 31.A OD2 no hydrogen 2.985 N/A ARG 76.A NH2 ASP 31.A O no hydrogen 3.153 N/A ARG 76.A NH2 ASP 31.A OD1 no hydrogen 2.981 N/A LYS 78.A N LEU 75.A O no hydrogen 2.772 N/A LEU 79.A N ARG 76.A O no hydrogen 3.375 N/A VAL 82.A N LYS 78.A O no hydrogen 3.143 N/A GLY 83.A N LEU 79.A O no hydrogen 2.984 N/A THR 84.A N GLN 80.A O no hydrogen 2.800 N/A THR 84.A OG1 GLN 80.A O no hydrogen 2.741 N/A ALA 85.A N LEU 81.A O no hydrogen 3.055 N/A ALA 86.A N VAL 82.A O no hydrogen 2.976 N/A MET 87.A N GLY 83.A O no hydrogen 3.042 N/A LEU 88.A N THR 84.A O no hydrogen 2.980 N/A LEU 89.A N ALA 85.A O no hydrogen 2.824 N/A ALA 90.A N ALA 86.A O no hydrogen 2.750 N/A SER 91.A N MET 87.A O no hydrogen 2.942 N/A SER 91.A OG MET 87.A O no hydrogen 2.615 N/A LYS 92.A N LEU 88.A O no hydrogen 2.947 N/A LYS 92.A NZ GLU 121.A OE1 no hydrogen 3.405 N/A LYS 92.A NZ GLU 121.A OE2 no hydrogen 2.678 N/A PHE 93.A N LEU 89.A O no hydrogen 2.962 N/A GLU 94.A N ALA 90.A O no hydrogen 2.805 N/A GLU 95.A N SER 91.A O no hydrogen 2.799 N/A GLU 100.A N GLU 103.A OE1 no hydrogen 3.208 N/A GLU 103.A N GLU 100.A O no hydrogen 3.010 N/A VAL 105.A N VAL 101.A O no hydrogen 2.930 N/A TYR 106.A N ALA 102.A O no hydrogen 2.896 N/A ILE 107.A N GLU 103.A O no hydrogen 3.161 N/A THR 108.A N VAL 105.A O no hydrogen 3.270 N/A THR 108.A OG1 VAL 105.A O no hydrogen 2.589 N/A ASP 109.A N TYR 106.A O no hydrogen 2.901 N/A THR 111.A N THR 108.A O no hydrogen 3.011 N/A THR 111.A OG1 THR 108.A O no hydrogen 2.244 N/A TYR 112.A OH GLY 77.A O no hydrogen 2.719 N/A THR 113.A N GLN 116.A OE1 no hydrogen 3.032 N/A GLN 116.A N THR 113.A OG1 no hydrogen 3.184 N/A VAL 117.A N THR 113.A O no hydrogen 3.232 N/A LEU 118.A N LYS 114.A O no hydrogen 3.011 N/A ARG 119.A N LYS 115.A O no hydrogen 2.923 N/A MET 120.A N GLN 116.A O no hydrogen 2.804 N/A GLU 121.A N VAL 117.A O no hydrogen 2.795 N/A HIS 122.A N LEU 118.A O no hydrogen 3.296 N/A LEU 123.A N ARG 119.A O no hydrogen 3.029 N/A VAL 124.A N MET 120.A O no hydrogen 2.848 N/A LEU 125.A N GLU 121.A O no hydrogen 3.102 N/A LYS 126.A N HIS 122.A O no hydrogen 2.962 N/A VAL 127.A N LEU 123.A O no hydrogen 2.846 N/A LEU 128.A N VAL 124.A O no hydrogen 2.940 N/A THR 129.A N LYS 126.A O no hydrogen 2.964 N/A THR 129.A OG1 LEU 128.A O no hydrogen 2.867 N/A THR 129.A OG1 ASP 131.A OD2 no hydrogen 2.782 N/A PHE 130.A N LEU 125.A O no hydrogen 2.795 N/A ASP 131.A N LEU 128.A O no hydrogen 2.972 N/A THR 136.A OG1 GLU 56.A OE1 no hydrogen 2.638 N/A THR 136.A OG1 GLU 56.A OE2 no hydrogen 3.395 N/A ASN 138.A ND2 GLU 56.A OE1 no hydrogen 2.967 N/A GLN 139.A N THR 136.A OG1 no hydrogen 3.054 N/A GLN 139.A NE2 GLU 56.A OE2 no hydrogen 2.615 N/A GLN 139.A NE2 ALA 134.A O no hydrogen 2.919 N/A PHE 140.A N THR 136.A O no hydrogen 3.413 N/A LEU 141.A N VAL 137.A O no hydrogen 2.948 N/A THR 142.A N ASN 138.A O no hydrogen 3.079 N/A THR 142.A OG1 GLN 139.A O no hydrogen 3.249 N/A TYR 144.A N PHE 140.A O no hydrogen 2.935 N/A TYR 144.A OH SER 179.A O no hydrogen 2.909 N/A PHE 145.A N LEU 141.A O no hydrogen 2.812 N/A LEU 146.A N GLN 143.A O no hydrogen 3.186 N/A HIS 147.A N TYR 144.A O no hydrogen 2.920 N/A HIS 147.A ND1 SER 201.A OG no hydrogen 2.652 N/A GLN 148.A N PHE 145.A O no hydrogen 3.312 N/A GLN 148.A NE2 PHE 145.A O no hydrogen 2.758 N/A GLN 148.A NE2 GLU 156.A OE2 no hydrogen 2.912 N/A ASN 152.A N GLN 148.A OE1 no hydrogen 3.154 N/A LYS 154.A N ASN 152.A OD1 no hydrogen 3.250 N/A VAL 155.A N ASN 152.A OD1 no hydrogen 3.318 N/A GLU 156.A N ASN 152.A O no hydrogen 3.115 N/A SER 157.A N CYS 153.A O no hydrogen 3.020 N/A SER 157.A OG CYS 153.A O no hydrogen 3.325 N/A SER 157.A OG HIS 245.A ND1 no hydrogen 2.778 N/A LEU 158.A N LYS 154.A O no hydrogen 2.887 N/A ALA 159.A N VAL 155.A O no hydrogen 2.902 N/A MET 160.A N GLU 156.A O no hydrogen 3.033 N/A PHE 161.A N SER 157.A O no hydrogen 2.819 N/A LEU 162.A N LEU 158.A O no hydrogen 2.908 N/A GLY 163.A N ALA 159.A O no hydrogen 2.835 N/A GLU 164.A N MET 160.A O no hydrogen 2.880 N/A LEU 165.A N PHE 161.A O no hydrogen 3.056 N/A SER 166.A N LEU 162.A O no hydrogen 3.289 N/A SER 166.A OG GLY 163.A O no hydrogen 2.701 N/A LEU 167.A N GLU 164.A O no hydrogen 3.171 N/A ILE 168.A N LEU 165.A O no hydrogen 3.068 N/A TYR 173.A N ASP 169.A O no hydrogen 3.256 N/A TYR 173.A OH THR 223.A OG1 no hydrogen 2.612 N/A LEU 174.A N ALA 170.A O no hydrogen 2.873 N/A LYS 175.A N PRO 172.A O no hydrogen 3.323 N/A TYR 176.A N TYR 173.A O no hydrogen 2.979 N/A TYR 176.A OH ASP 219.A OD2 no hydrogen 2.699 N/A SER 179.A N GLU 16.A OE1 no hydrogen 2.853 N/A SER 179.A OG GLU 16.A OE1 no hydrogen 3.365 N/A SER 179.A OG GLU 16.A OE2 no hydrogen 2.477 N/A SER 179.A OG TYR 208.A OH no hydrogen 2.644 N/A VAL 180.A N LEU 177.A O no hydrogen 2.978 N/A ILE 181.A N LEU 177.A O no hydrogen 2.979 N/A ALA 182.A N PRO 178.A O no hydrogen 2.907 N/A GLY 183.A N SER 179.A O no hydrogen 3.062 N/A ALA 184.A N VAL 180.A O no hydrogen 2.982 N/A ALA 185.A N ILE 181.A O no hydrogen 2.754 N/A PHE 186.A N ALA 182.A O no hydrogen 2.878 N/A HIS 187.A N GLY 183.A O no hydrogen 2.987 N/A LEU 188.A N ALA 184.A O no hydrogen 2.944 N/A ALA 189.A N ALA 185.A O no hydrogen 2.956 N/A LEU 190.A N PHE 186.A O no hydrogen 2.988 N/A TYR 191.A N HIS 187.A O no hydrogen 2.812 N/A THR 192.A N LEU 188.A O no hydrogen 2.950 N/A THR 192.A OG1 LEU 188.A O no hydrogen 2.749 N/A VAL 193.A N ALA 189.A O no hydrogen 3.114 N/A THR 194.A N LEU 190.A O no hydrogen 2.898 N/A THR 194.A OG1 LEU 190.A O no hydrogen 2.733 N/A GLY 195.A N TYR 191.A O no hydrogen 2.984 N/A GLN 196.A N THR 194.A OG1 no hydrogen 3.235 N/A GLN 196.A NE2 THR 194.A OG1 no hydrogen 2.978 N/A TRP 198.A N HIS 187.A ND1 no hydrogen 3.073 N/A TRP 198.A NE1 TYR 208.A O no hydrogen 2.939 N/A SER 201.A OG HIS 147.A ND1 no hydrogen 2.652 N/A LEU 202.A N PRO 199.A O no hydrogen 3.011 N/A ILE 203.A N PRO 199.A O no hydrogen 3.344 N/A ARG 204.A N GLU 200.A O no hydrogen 3.101 N/A ARG 204.A NE GLU 200.A OE2 no hydrogen 3.170 N/A LYS 205.A N SER 201.A O no hydrogen 3.150 N/A THR 206.A N LEU 202.A O no hydrogen 2.816 N/A THR 206.A OG1 LEU 202.A O no hydrogen 2.684 N/A GLY 207.A N ILE 203.A O no hydrogen 2.641 N/A TYR 208.A N THR 206.A OG1 no hydrogen 2.914 N/A TYR 208.A OH SER 179.A OG no hydrogen 2.644 N/A THR 209.A N SER 212.A OG no hydrogen 2.973 N/A SER 212.A N THR 209.A OG1 no hydrogen 3.390 N/A SER 212.A OG THR 209.A O no hydrogen 3.004 N/A LEU 213.A N THR 209.A O no hydrogen 2.999 N/A LEU 217.A N LEU 213.A O no hydrogen 2.798 N/A MET 218.A N LYS 214.A O no hydrogen 2.642 N/A ASP 219.A N PRO 215.A O no hydrogen 3.133 N/A LEU 220.A N CYS 216.A O no hydrogen 2.706 N/A HIS 221.A N LEU 217.A O no hydrogen 2.808 N/A GLN 222.A N MET 218.A O no hydrogen 3.376 N/A THR 223.A N ASP 219.A O no hydrogen 3.013 N/A THR 223.A OG1 TYR 173.A OH no hydrogen 2.612 N/A THR 223.A OG1 ASP 219.A O no hydrogen 3.286 N/A TYR 224.A N LEU 220.A O no hydrogen 2.811 N/A LEU 225.A N HIS 221.A O no hydrogen 2.993 N/A LYS 226.A N GLN 222.A O no hydrogen 2.926 N/A ALA 227.A N TYR 224.A O no hydrogen 3.129 N/A GLN 229.A N LYS 226.A O no hydrogen 3.047 N/A HIS 230.A N LYS 226.A O no hydrogen 3.210 N/A HIS 230.A N ALA 227.A O no hydrogen 3.264 N/A HIS 230.A NE2 ASP 169.A OD1 no hydrogen 2.842 N/A GLN 232.A N HIS 230.A ND1 no hydrogen 2.863 N/A GLN 233.A NE2 ALA 227.A O no hydrogen 2.736 N/A GLN 233.A NE2 HIS 230.A O no hydrogen 2.730 N/A SER 234.A N ASP 42.A OD2 no hydrogen 2.968 N/A SER 234.A OG ASP 42.A OD1 no hydrogen 2.594 N/A SER 234.A OG ASP 42.A OD2 no hydrogen 3.267 N/A ARG 236.A NH1 GLN 233.A OE1 no hydrogen 2.763 N/A GLU 237.A N GLN 233.A O no hydrogen 3.072 N/A LYS 238.A N SER 234.A O no hydrogen 2.958 N/A LYS 238.A NZ ASN 55.A OD1 no hydrogen 2.734 N/A LYS 238.A NZ GLU 164.A OE1 no hydrogen 3.343 N/A LYS 238.A NZ GLU 164.A OE2 no hydrogen 2.694 N/A TYR 239.A N ILE 235.A O no hydrogen 2.855 N/A TYR 239.A OH GLU 164.A OE1 no hydrogen 2.745 N/A LYS 240.A N GLU 237.A O no hydrogen 3.182 N/A LYS 240.A NZ GLU 237.A OE1 no hydrogen 3.353 N/A ASN 241.A N LYS 238.A O no hydrogen 3.259 N/A LYS 243.A N ASN 241.A OD1 no hydrogen 2.904 N/A TYR 244.A N ASN 241.A O no hydrogen 3.018 N/A HIS 245.A N SER 242.A O no hydrogen 2.916 N/A HIS 245.A ND1 SER 157.A OG no hydrogen 2.778 N/A GLY 246.A N ASN 241.A O no hydrogen 3.134 N/A VAL 247.A N TYR 244.A O no hydrogen 3.386 N/A SER 248.A N TYR 239.A O no hydrogen 3.220 N/A SER 248.A OG ARG 236.A O no hydrogen 2.724 N/A LEU 249.A N GLY 246.A O no hydrogen 2.968 N/A LEU 250.A N VAL 247.A O no hydrogen 3.148 N/A