Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 1ryo_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 2.A OG1 SER 33.A OG no hydrogen 2.578 N/A VAL 3.A N SER 33.A O no hydrogen 2.951 N/A ARG 4.A N ASP 55.A OD2 no hydrogen 2.838 N/A ARG 4.A NE ASP 55.A OD1 no hydrogen 3.441 N/A ARG 4.A NE ASP 55.A OD2 no hydrogen 2.968 N/A ARG 4.A NH1 ASN 52.A O no hydrogen 2.951 N/A ARG 4.A NH2 ASN 52.A O no hydrogen 3.379 N/A ARG 4.A NH2 ASN 52.A OD1 no hydrogen 2.965 N/A ARG 4.A NH2 ASP 55.A OD1 no hydrogen 2.778 N/A TRP 5.A N ALA 35.A O no hydrogen 2.749 N/A CYS 6.A N ALA 56.A O no hydrogen 2.909 N/A CYS 6.A SG VAL 37.A O no hydrogen 3.797 N/A ALA 7.A N VAL 37.A O no hydrogen 2.850 N/A VAL 8.A N GLU 12.A OE1 no hydrogen 2.809 N/A SER 9.A N LYS 39.A O no hydrogen 2.769 N/A GLU 10.A N SER 9.A OG no hydrogen 2.794 N/A HIS 11.A ND1 THR 178.A OG1 no hydrogen 2.770 N/A ALA 13.A N SER 9.A O no hydrogen 3.046 N/A THR 14.A N GLU 10.A O no hydrogen 2.952 N/A THR 14.A OG1 GLU 10.A O no hydrogen 2.977 N/A LYS 15.A N HIS 11.A O no hydrogen 3.079 N/A LYS 15.A NZ LEU 281.A O no hydrogen 2.808 N/A LYS 15.A NZ SER 283.A O no hydrogen 3.331 N/A LYS 15.A NZ LEU 290.A O no hydrogen 2.793 N/A CYS 16.A N GLU 12.A O no hydrogen 2.755 N/A GLN 17.A N ALA 13.A O no hydrogen 2.926 N/A GLN 17.A NE2 ASP 21.A OD2 no hydrogen 2.718 N/A SER 18.A N THR 14.A O no hydrogen 3.098 N/A SER 18.A OG THR 14.A O no hydrogen 3.349 N/A SER 18.A OG GLN 17.A OE1 no hydrogen 3.337 N/A PHE 19.A N LYS 15.A O no hydrogen 2.837 N/A ARG 20.A N CYS 16.A O no hydrogen 2.932 N/A ASP 21.A N GLN 17.A O no hydrogen 2.937 N/A HIS 22.A N SER 18.A O no hydrogen 2.835 N/A MET 23.A N PHE 19.A O no hydrogen 2.966 N/A LYS 24.A N ARG 20.A O no hydrogen 3.067 N/A LYS 24.A NZ ASP 21.A OD1 no hydrogen 3.406 N/A SER 25.A N ASP 21.A O no hydrogen 3.173 N/A SER 25.A N HIS 22.A O no hydrogen 3.119 N/A SER 25.A OG HIS 22.A O no hydrogen 2.630 N/A VAL 26.A N MET 23.A O no hydrogen 3.127 N/A ILE 27.A N MET 23.A O no hydrogen 2.721 N/A GLY 31.A N PRO 28.A O no hydrogen 2.765 N/A SER 33.A N LYS 1.A O no hydrogen 3.408 N/A SER 33.A OG LYS 1.A O no hydrogen 3.520 N/A ALA 35.A N VAL 3.A O no hydrogen 2.862 N/A VAL 37.A N TRP 5.A O no hydrogen 2.850 N/A LYS 38.A NZ GLU 10.A OE1 no hydrogen 3.289 N/A LYS 38.A NZ GLU 10.A OE2 no hydrogen 2.635 N/A LYS 39.A N ALA 7.A O no hydrogen 2.804 N/A LEU 43.A N SER 41.A OG no hydrogen 3.263 N/A ASP 44.A N SER 41.A O no hydrogen 3.050 N/A CYS 45.A N SER 41.A O no hydrogen 3.313 N/A CYS 45.A SG SER 41.A O no hydrogen 3.927 N/A ILE 46.A N TYR 42.A O no hydrogen 2.952 N/A ARG 47.A N LEU 43.A O no hydrogen 3.186 N/A ALA 48.A N ASP 44.A O no hydrogen 2.914 N/A ILE 49.A N CYS 45.A O no hydrogen 2.937 N/A ALA 50.A N ILE 46.A O no hydrogen 3.081 N/A ALA 51.A N ARG 47.A O no hydrogen 2.897 N/A ASN 52.A N ILE 49.A O no hydrogen 3.094 N/A GLU 53.A N ALA 48.A O no hydrogen 2.789 N/A ASP 55.A N ARG 4.A O no hydrogen 2.803 N/A ALA 56.A N ARG 4.A O no hydrogen 3.195 N/A THR 58.A OG1 LEU 291.A O no hydrogen 2.856 N/A LEU 59.A N THR 247.A O no hydrogen 2.846 N/A GLY 62.A N ASP 60.A OD2 no hydrogen 2.840 N/A VAL 64.A N ASP 60.A O no hydrogen 2.938 N/A TYR 65.A N ALA 61.A O no hydrogen 3.164 N/A ASP 66.A N GLY 62.A O no hydrogen 3.328 N/A ALA 67.A N LEU 63.A O no hydrogen 2.831 N/A TYR 68.A N VAL 64.A O no hydrogen 3.182 N/A TYR 68.A N TYR 65.A O no hydrogen 3.048 N/A LEU 69.A N ASP 66.A O no hydrogen 3.198 N/A ASN 72.A N LEU 69.A O no hydrogen 3.154 N/A ASN 73.A N LEU 69.A O no hydrogen 3.163 N/A LEU 74.A N ALA 67.A O no hydrogen 2.899 N/A LYS 75.A N ALA 250.A O no hydrogen 2.867 N/A LYS 75.A NZ ARG 305.A O no hydrogen 3.080 N/A VAL 77.A N VAL 248.A O no hydrogen 2.848 N/A ALA 79.A N LEU 300.A O no hydrogen 2.822 N/A GLU 80.A N HIS 246.A O no hydrogen 2.966 N/A PHE 81.A N GLY 298.A O no hydrogen 3.062 N/A TYR 82.A N GLN 89.A O no hydrogen 2.769 N/A TYR 82.A OH GLU 80.A OE1 no hydrogen 2.671 N/A LYS 85.A NZ LYS 273.A O no hydrogen 3.263 N/A GLU 86.A N GLU 86.A OE2 no hydrogen 2.617 N/A ASP 87.A N SER 84.A OG no hydrogen 3.100 N/A GLN 89.A N TYR 82.A O no hydrogen 2.871 N/A TYR 92.A N VAL 243.A O no hydrogen 2.973 N/A TYR 92.A OH TYR 185.A OH no hydrogen 2.894 N/A TYR 92.A OH HIS 246.A NE2 no hydrogen 3.111 N/A TYR 93.A N HIS 204.A ND1 no hydrogen 3.237 N/A ALA 94.A N ALA 241.A O no hydrogen 2.889 N/A VAL 95.A N VAL 202.A O no hydrogen 2.867 N/A VAL 97.A N ALA 200.A O no hydrogen 2.890 N/A VAL 98.A N GLU 221.A O no hydrogen 2.872 N/A LYS 99.A NZ LYS 193.A O no hydrogen 2.988 N/A LYS 100.A N GLN 219.A O no hydrogen 2.864 N/A SER 102.A N LYS 99.A O no hydrogen 3.335 N/A SER 102.A OG LYS 99.A O no hydrogen 2.979 N/A GLN 105.A N GLN 108.A OE1 no hydrogen 2.878 N/A ASN 107.A N ASN 227.A OD1 no hydrogen 3.055 N/A GLN 108.A N GLN 105.A O no hydrogen 2.880 N/A GLY 111.A N PHE 150.A O no hydrogen 2.914 N/A LYS 112.A N LEU 109.A O no hydrogen 2.970 N/A LYS 112.A NZ GLN 108.A O no hydrogen 2.902 N/A LYS 113.A N ASP 198.A OD2 no hydrogen 2.854 N/A LYS 113.A NZ SER 152.A O no hydrogen 3.234 N/A LYS 113.A NZ SER 152.A OG no hydrogen 2.915 N/A SER 114.A N GLY 153.A O no hydrogen 3.081 N/A SER 114.A OG HIS 116.A NE2 no hydrogen 2.761 N/A CYS 115.A N VAL 199.A O no hydrogen 2.896 N/A HIS 116.A N CYS 155.A O no hydrogen 2.902 N/A HIS 116.A ND1 GLY 124.A O no hydrogen 2.813 N/A HIS 116.A NE2 SER 114.A OG no hydrogen 2.761 N/A LEU 119.A N PRO 157.A O no hydrogen 2.850 N/A ARG 121.A N.A GLY 118.A O no hydrogen 3.366 N/A ARG 121.A N.B GLY 118.A O no hydrogen 3.365 N/A SER 122.A N ASP 60.A OD1 no hydrogen 3.357 N/A SER 122.A N ASP 60.A OD2 no hydrogen 2.808 N/A SER 122.A OG ASP 60.A OD1 no hydrogen 3.316 N/A SER 122.A OG ASP 60.A OD2 no hydrogen 3.273 N/A SER 122.A OG TYR 316.A OH no hydrogen 2.618 N/A TRP 125.A N ARG 121.A O.A no hydrogen 2.986 N/A TRP 125.A N ARG 121.A O.B no hydrogen 3.006 N/A ASN 126.A N ARG 121.A O.A no hydrogen 2.875 N/A ASN 126.A N ARG 121.A O.B no hydrogen 2.848 N/A ASN 126.A ND2 GLY 120.A O no hydrogen 3.288 N/A ASN 126.A ND2 TYR 316.A OH no hydrogen 3.059 N/A ILE 127.A N SER 122.A O no hydrogen 3.001 N/A ILE 129.A N TRP 125.A O no hydrogen 2.891 N/A GLY 130.A N ASN 126.A O no hydrogen 3.083 N/A LEU 131.A N ILE 127.A O no hydrogen 3.063 N/A LEU 132.A N PRO 128.A O no hydrogen 2.987 N/A ASP 135.A N LEU 132.A O no hydrogen 2.802 N/A LEU 136.A N LEU 132.A O no hydrogen 3.233 N/A LEU 136.A N TYR 133.A O no hydrogen 3.114 N/A ARG 140.A NE TYR 133.A O no hydrogen 3.150 N/A ARG 140.A NE LEU 136.A O no hydrogen 3.131 N/A ARG 140.A NH2 CYS 134.A O no hydrogen 3.078 N/A GLU 144.A N GLU 144.A OE1 no hydrogen 2.778 N/A LYS 145.A N PRO 142.A O no hydrogen 3.184 N/A LYS 145.A NZ ASN 149.A OD1 no hydrogen 3.025 N/A ALA 146.A N PRO 142.A O no hydrogen 3.275 N/A VAL 147.A N LEU 143.A O no hydrogen 2.960 N/A ALA 148.A N GLU 144.A O no hydrogen 2.994 N/A ASN 149.A N LYS 145.A O no hydrogen 2.841 N/A PHE 150.A N ALA 146.A O no hydrogen 2.978 N/A PHE 151.A N VAL 147.A O no hydrogen 3.179 N/A SER 152.A N LYS 112.A O no hydrogen 2.890 N/A SER 152.A OG GLY 111.A O no hydrogen 2.681 N/A SER 154.A N GLN 166.A O no hydrogen 3.077 N/A SER 154.A OG GLN 166.A O no hydrogen 3.495 N/A CYS 155.A N SER 114.A O no hydrogen 2.945 N/A ALA 156.A N LEU 167.A O no hydrogen 2.821 N/A CYS 158.A N CYS 174.A O no hydrogen 2.820 N/A ALA 159.A N ALA 156.A O no hydrogen 3.093 N/A THR 162.A N ASP 160.A OD1 no hydrogen 2.784 N/A ASP 163.A N ASP 160.A OD1 no hydrogen 3.040 N/A PHE 164.A N ASP 160.A O no hydrogen 2.897 N/A GLN 166.A N GLN 166.A OE1 no hydrogen 2.962 N/A LEU 167.A N PHE 164.A O no hydrogen 2.952 N/A CYS 168.A N PRO 165.A O no hydrogen 3.029 N/A GLN 169.A N GLN 166.A O no hydrogen 3.326 N/A GLN 169.A NE2 SER 152.A O no hydrogen 3.396 N/A LEU 170.A N SER 154.A O no hydrogen 2.976 N/A CYS 171.A N CYS 168.A O no hydrogen 3.036 N/A CYS 174.A N CYS 171.A O no hydrogen 2.866 N/A CYS 174.A SG ALA 156.A O no hydrogen 3.319 N/A CYS 174.A SG LEU 167.A O no hydrogen 3.176 N/A CYS 176.A SG SER 41.A OG no hydrogen 3.374 N/A THR 178.A OG1 HIS 11.A ND1 no hydrogen 2.770 N/A LEU 179.A N SER 177.A OG no hydrogen 3.129 N/A ASN 180.A N SER 177.A O no hydrogen 2.934 N/A ASN 180.A ND2 GLY 175.A O no hydrogen 3.000 N/A TYR 182.A N ASN 180.A OD1 no hydrogen 2.986 N/A TYR 182.A OH ASP 194.A OD2 no hydrogen 2.633 N/A PHE 183.A N ASN 180.A O no hydrogen 3.058 N/A GLY 184.A N THR 117.A O no hydrogen 3.038 N/A TYR 185.A OH HIS 246.A NE2 no hydrogen 3.125 N/A ALA 188.A N GLY 184.A O no hydrogen 2.868 N/A PHE 189.A N TYR 185.A O no hydrogen 3.047 N/A LYS 190.A N SER 186.A O no hydrogen 2.972 N/A LYS 190.A NZ GLN 181.A OE1 no hydrogen 2.750 N/A LYS 190.A NZ ASP 194.A OD2 no hydrogen 2.770 N/A CYS 191.A N GLY 187.A O no hydrogen 2.975 N/A LEU 192.A N ALA 188.A O no hydrogen 3.220 N/A LYS 193.A N PHE 189.A O no hydrogen 2.824 N/A ASP 194.A N LYS 190.A O no hydrogen 2.769 N/A GLY 195.A N LEU 192.A O no hydrogen 2.972 N/A ALA 196.A N CYS 191.A O no hydrogen 3.033 N/A GLY 197.A N CYS 191.A O no hydrogen 3.162 N/A ASP 198.A N LYS 113.A O no hydrogen 2.787 N/A VAL 199.A N LYS 113.A O no hydrogen 3.335 N/A ALA 200.A N VAL 97.A O no hydrogen 2.885 N/A PHE 201.A N CYS 115.A O no hydrogen 3.050 N/A VAL 202.A N VAL 95.A O no hydrogen 3.127 N/A LYS 203.A N THR 206.A OG1 no hydrogen 3.161 N/A LYS 203.A NZ SER 295.A OG no hydrogen 2.996 N/A HIS 204.A N TYR 93.A O no hydrogen 2.977 N/A SER 205.A OG GLU 209.A OE2 no hydrogen 2.765 N/A THR 206.A N LYS 203.A O no hydrogen 3.178 N/A THR 206.A OG1 LYS 203.A O no hydrogen 3.106 N/A GLU 209.A N SER 205.A O no hydrogen 3.034 N/A GLU 209.A N THR 206.A O no hydrogen 3.112 N/A ASN 210.A N ILE 207.A O no hydrogen 3.120 N/A ASN 210.A ND2 SER 186.A OG no hydrogen 2.939 N/A ASN 210.A ND2 THR 206.A O no hydrogen 2.832 N/A LEU 211.A N ILE 207.A O no hydrogen 2.912 N/A ASN 213.A ND2 ASP 216.A OD2 no hydrogen 3.509 N/A LYS 214.A NZ ASP 218.A OD1 no hydrogen 2.920 N/A ASP 216.A N ASN 213.A O no hydrogen 2.992 N/A ARG 217.A N ASN 213.A O no hydrogen 3.211 N/A ARG 217.A NH1 LEU 211.A O no hydrogen 2.882 N/A ARG 217.A NH1 ALA 212.A O no hydrogen 3.053 N/A ASP 218.A N LYS 214.A O no hydrogen 2.830 N/A GLN 219.A N ASP 216.A O no hydrogen 3.154 N/A TYR 220.A N ARG 217.A O no hydrogen 2.899 N/A GLU 221.A N VAL 98.A O no hydrogen 2.842 N/A LEU 222.A N LYS 230.A O no hydrogen 2.830 N/A LEU 223.A N ALA 96.A O no hydrogen 2.965 N/A CYS 224.A N THR 228.A O no hydrogen 2.889 N/A CYS 224.A SG THR 228.A O no hydrogen 3.430 N/A ASN 227.A N CYS 224.A O no hydrogen 3.116 N/A THR 228.A OG1 ASP 226.A OD1 no hydrogen 2.613 N/A THR 228.A OG1 ASP 226.A OD2 no hydrogen 3.325 N/A ARG 229.A NE PHE 104.A O no hydrogen 2.985 N/A ARG 229.A NH1 LYS 99.A O no hydrogen 2.933 N/A ARG 229.A NH1 SER 102.A OG no hydrogen 3.213 N/A ARG 229.A NH1 GLU 221.A OE1 no hydrogen 3.068 N/A ARG 229.A NH2 SER 102.A OG no hydrogen 2.649 N/A ARG 229.A NH2 PHE 104.A O no hydrogen 2.892 N/A LYS 230.A N LEU 222.A O no hydrogen 3.082 N/A LYS 230.A NZ ASP 237.A O no hydrogen 3.203 N/A GLU 234.A N PRO 231.A O no hydrogen 2.964 N/A LYS 236.A NZ TYR 235.A OH no hydrogen 2.896 N/A ASP 237.A N GLU 234.A O no hydrogen 2.968 N/A CYS 238.A N TYR 235.A O no hydrogen 3.070 N/A HIS 239.A ND1 TYR 235.A O no hydrogen 2.876 N/A LEU 240.A N ALA 94.A O no hydrogen 2.818 N/A VAL 243.A N TYR 92.A O no hydrogen 2.888 N/A SER 245.A N THR 90.A O no hydrogen 3.099 N/A SER 245.A OG GLU 80.A O no hydrogen 2.888 N/A SER 245.A OG THR 90.A O no hydrogen 3.479 N/A SER 245.A OG TYR 311.A OH no hydrogen 3.019 N/A HIS 246.A N TYR 82.A OH no hydrogen 3.077 N/A HIS 246.A NE2 TYR 92.A OH no hydrogen 3.111 N/A THR 247.A N LEU 59.A O no hydrogen 3.021 N/A VAL 248.A N VAL 78.A O no hydrogen 2.723 N/A VAL 249.A N VAL 57.A O no hydrogen 2.924 N/A ALA 250.A N LYS 75.A O no hydrogen 2.909 N/A ARG 251.A NE MET 253.A O no hydrogen 3.416 N/A ARG 251.A NE GLY 254.A O no hydrogen 3.208 N/A ARG 251.A NH1 ILE 49.A O no hydrogen 2.874 N/A ARG 251.A NH1 ALA 54.A O no hydrogen 2.774 N/A ARG 251.A NH2 ASP 55.A OD1 no hydrogen 2.824 N/A ARG 251.A NH2 GLY 254.A O no hydrogen 2.831 N/A LYS 256.A NZ THR 2.A O no hydrogen 2.924 N/A LYS 256.A NZ ASP 55.A OD2 no hydrogen 2.948 N/A ILE 260.A N LYS 256.A O no hydrogen 2.834 N/A TRP 261.A N GLU 257.A O no hydrogen 3.075 N/A GLU 262.A N ASP 258.A O no hydrogen 2.977 N/A LEU 263.A N LEU 259.A O no hydrogen 2.862 N/A LEU 264.A N ILE 260.A O no hydrogen 2.972 N/A ASN 265.A N TRP 261.A O no hydrogen 2.762 N/A GLN 266.A N GLU 262.A O no hydrogen 3.069 N/A ALA 267.A N LEU 263.A O no hydrogen 2.842 N/A GLN 268.A N LEU 264.A O no hydrogen 2.906 N/A GLN 268.A NE2 ASN 265.A OD1 no hydrogen 2.933 N/A GLN 268.A NE2 PHE 299.A O no hydrogen 3.494 N/A GLU 269.A N ASN 265.A O no hydrogen 3.370 N/A HIS 270.A N GLN 266.A O no hydrogen 3.060 N/A PHE 271.A N ALA 267.A O no hydrogen 2.697 N/A LYS 273.A NZ ASP 294.A O no hydrogen 2.959 N/A LYS 273.A NZ ALA 296.A O no hydrogen 2.812 N/A LYS 275.A N GLY 272.A O no hydrogen 3.088 N/A LYS 275.A NZ GLU 269.A O no hydrogen 2.655 N/A GLU 278.A N SER 276.A OG no hydrogen 2.905 N/A PHE 279.A N SER 276.A OG no hydrogen 3.249 N/A GLN 280.A NE2 SER 276.A O no hydrogen 2.982 N/A LEU 281.A N PHE 271.A O no hydrogen 2.985 N/A HIS 286.A N SER 284.A OG no hydrogen 2.988 N/A GLY 287.A N SER 284.A O no hydrogen 3.416 N/A LYS 288.A NZ GLU 209.A O no hydrogen 2.934 N/A ASP 289.A N ASP 294.A OD1 no hydrogen 2.896 N/A LEU 291.A N GLU 12.A OE2 no hydrogen 2.902 N/A LYS 293.A N GLU 80.A OE2 no hydrogen 2.899 N/A LYS 293.A NZ TYR 82.A OH no hydrogen 3.447 N/A LYS 293.A NZ TYR 185.A OH no hydrogen 2.949 N/A ASP 294.A N ASP 289.A OD1 no hydrogen 2.844 N/A ALA 296.A N LYS 293.A O no hydrogen 3.040 N/A HIS 297.A N PHE 81.A O no hydrogen 2.831 N/A PHE 299.A N GLN 268.A OE1 no hydrogen 2.912 N/A LEU 300.A N ALA 79.A O no hydrogen 2.855 N/A VAL 302.A N VAL 77.A O no hydrogen 3.039 N/A MET 306.A N PRO 303.A O no hydrogen 3.266 N/A MET 310.A N ASP 307.A OD2 no hydrogen 2.815 N/A TYR 311.A N ASP 307.A O no hydrogen 2.993 N/A TYR 311.A OH SER 245.A O no hydrogen 2.827 N/A LEU 312.A N ALA 308.A O no hydrogen 2.866 N/A GLY 313.A N LYS 309.A O no hydrogen 3.153 N/A VAL 317.A N GLY 313.A O no hydrogen 3.056 N/A THR 318.A N TYR 314.A O no hydrogen 2.878 N/A THR 318.A OG1 TYR 314.A O no hydrogen 2.710 N/A ALA 319.A N GLU 315.A O no hydrogen 3.054 N/A ILE 320.A N TYR 316.A O no hydrogen 3.041 N/A ARG 321.A N VAL 317.A O no hydrogen 2.906 N/A ARG 321.A NH2 THR 318.A OG1 no hydrogen 2.862 N/A ASN 322.A N THR 318.A O no hydrogen 2.837 N/A LEU 323.A N ALA 319.A O no hydrogen 3.209 N/A ARG 324.A N ILE 320.A O no hydrogen 3.093 N/A ARG 324.A NH1 ASP 66.A OD1 no hydrogen 3.341 N/A ARG 324.A NH2 ASP 66.A OD1 no hydrogen 2.740 N/A