Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 1s5l_D.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASP 6.A N PHE 2.A O no hydrogen 2.969 N/A ASP 7.A N ASP 3.A O no hydrogen 2.830 N/A TRP 8.A N ILE 4.A O no hydrogen 2.618 N/A LEU 9.A N LEU 5.A O no hydrogen 2.637 N/A LYS 10.A N ASP 6.A O no hydrogen 2.583 N/A LYS 10.A NZ ASP 6.A OD2 no hydrogen 3.320 N/A ARG 11.A N TRP 8.A O no hydrogen 3.043 N/A ARG 13.A NE ARG 11.A O no hydrogen 3.381 N/A ARG 13.A NH2 TRP 8.A O no hydrogen 2.402 N/A TRP 19.A N GLU 118.A OE2 no hydrogen 2.349 N/A SER 20.A N GLU 118.A OE2 no hydrogen 3.216 N/A GLY 21.A N GLY 18.A O no hydrogen 2.724 N/A ILE 22.A N TRP 19.A O no hydrogen 3.497 N/A LEU 23.A N SER 20.A O no hydrogen 2.911 N/A LEU 24.A N SER 20.A O no hydrogen 3.212 N/A CYS 27.A N LEU 23.A O no hydrogen 3.227 N/A CYS 27.A SG LEU 23.A O no hydrogen 3.062 N/A ALA 28.A N LEU 24.A O no hydrogen 2.654 N/A TYR 29.A N PHE 25.A O no hydrogen 3.184 N/A LEU 30.A N PRO 26.A O no hydrogen 3.211 N/A ALA 31.A N CYS 27.A O no hydrogen 2.857 N/A LEU 32.A N TYR 29.A O no hydrogen 3.021 N/A GLY 33.A N TYR 29.A O no hydrogen 2.816 N/A GLY 34.A N LEU 30.A O no hydrogen 2.633 N/A TRP 35.A NE1 PHE 160.A O no hydrogen 3.250 N/A LEU 36.A N LEU 32.A O no hydrogen 2.955 N/A THR 37.A N GLY 33.A O no hydrogen 2.661 N/A THR 37.A OG1 GLY 33.A O no hydrogen 2.318 N/A GLY 38.A N GLY 34.A O no hydrogen 3.398 N/A THR 39.A N TRP 35.A O no hydrogen 2.807 N/A THR 39.A OG1 TRP 35.A O no hydrogen 2.538 N/A THR 40.A N LEU 36.A O no hydrogen 3.257 N/A THR 40.A OG1 LEU 36.A O no hydrogen 3.159 N/A PHE 41.A N THR 37.A O no hydrogen 2.782 N/A VAL 42.A N GLY 38.A O no hydrogen 2.736 N/A THR 43.A OG1 GLU 56.A OE1 no hydrogen 2.963 N/A THR 47.A OG1 THR 67.A O no hydrogen 3.558 N/A HIS 48.A N SER 44.A O no hydrogen 3.051 N/A HIS 48.A ND1 THR 67.A O no hydrogen 2.985 N/A SER 52.A OG ALA 64.A O no hydrogen 2.311 N/A SER 53.A N GLU 56.A OE2 no hydrogen 3.428 N/A SER 53.A OG VAL 42.A O no hydrogen 3.166 N/A SER 53.A OG GLU 56.A OE2 no hydrogen 3.555 N/A LEU 55.A N SER 53.A OG no hydrogen 2.993 N/A GLY 57.A N TYR 54.A O no hydrogen 2.690 N/A CYS 58.A N SER 53.A O no hydrogen 2.984 N/A CYS 58.A SG ALA 51.A O no hydrogen 3.591 N/A CYS 58.A SG SER 53.A O no hydrogen 2.736 N/A THR 62.A N ASN 59.A OD1 no hydrogen 2.770 N/A VAL 63.A N ASN 59.A O no hydrogen 2.919 N/A ALA 64.A N SER 52.A O no hydrogen 2.845 N/A VAL 65.A N PHE 160.A O no hydrogen 2.715 N/A SER 66.A OG SER 44.A OG no hydrogen 3.129 N/A THR 67.A OG1 PHE 155.A O no hydrogen 3.443 N/A THR 67.A OG1 ALA 157.A O no hydrogen 3.464 N/A ASN 70.A ND2 SER 152.A OG no hydrogen 2.929 N/A ASN 70.A ND2 SER 153.A OG no hydrogen 2.995 N/A MET 72.A N ALA 69.A O no hydrogen 2.880 N/A GLY 73.A N ASN 70.A O no hydrogen 3.482 N/A SER 75.A N MET 72.A O no hydrogen 3.369 N/A SER 75.A OG MET 72.A O no hydrogen 2.782 N/A GLY 81.A N LEU 78.A O no hydrogen 2.561 N/A GLN 85.A N GLY 81.A O no hydrogen 2.976 N/A GLY 86.A N LEU 79.A O no hydrogen 2.858 N/A ASP 87.A N ALA 84.A O no hydrogen 3.449 N/A ARG 90.A N ASP 87.A OD1 no hydrogen 3.341 N/A TRP 91.A N ASP 87.A O no hydrogen 2.890 N/A TRP 91.A NE1 LEU 77.A O no hydrogen 2.660 N/A CYS 92.A N PHE 88.A O no hydrogen 2.940 N/A CYS 92.A N THR 89.A O no hydrogen 3.088 N/A CYS 92.A SG PHE 88.A O no hydrogen 3.789 N/A GLN 93.A N THR 89.A O no hydrogen 3.002 N/A LEU 94.A N ARG 90.A O no hydrogen 2.771 N/A GLY 95.A N CYS 92.A O no hydrogen 2.897 N/A TRP 98.A N GLY 95.A O no hydrogen 2.879 N/A ILE 101.A N LEU 97.A O no hydrogen 2.875 N/A ALA 102.A N TRP 98.A O no hydrogen 2.861 N/A LEU 103.A N THR 99.A O no hydrogen 2.893 N/A HIS 104.A N PHE 100.A O no hydrogen 2.967 N/A GLY 105.A N ILE 101.A O no hydrogen 2.743 N/A ALA 106.A N LEU 103.A O no hydrogen 2.744 N/A PHE 107.A N LEU 103.A O no hydrogen 3.089 N/A GLY 108.A N HIS 104.A O no hydrogen 2.966 N/A LEU 109.A N ALA 106.A O no hydrogen 3.240 N/A ILE 110.A N ALA 106.A O no hydrogen 3.226 N/A GLY 111.A N PHE 107.A O no hydrogen 2.663 N/A PHE 112.A N GLY 108.A O no hydrogen 2.821 N/A LEU 114.A N ILE 110.A O no hydrogen 3.267 N/A ARG 115.A N GLY 111.A O no hydrogen 2.753 N/A GLN 116.A N MET 113.A O no hydrogen 3.241 N/A PHE 117.A N LEU 114.A O no hydrogen 2.943 N/A GLU 118.A N LEU 114.A O no hydrogen 2.945 N/A ILE 119.A N ARG 115.A O no hydrogen 3.412 N/A ALA 120.A N PHE 117.A O no hydrogen 3.028 N/A ARG 121.A N GLU 118.A O no hydrogen 2.660 N/A VAL 123.A N ILE 119.A O no hydrogen 3.259 N/A ILE 131.A N TYR 128.A O no hydrogen 2.884 N/A ALA 132.A N TYR 128.A O no hydrogen 2.913 N/A PHE 133.A N ASN 129.A O no hydrogen 3.071 N/A SER 134.A N ILE 131.A O no hydrogen 3.084 N/A SER 134.A OG ILE 131.A O no hydrogen 2.577 N/A ALA 135.A N ALA 132.A O no hydrogen 3.410 N/A ILE 137.A N PHE 133.A O no hydrogen 3.491 N/A ALA 138.A N SER 134.A O no hydrogen 2.761 N/A ALA 138.A N ALA 135.A O no hydrogen 2.800 N/A VAL 139.A N ALA 135.A O no hydrogen 2.842 N/A PHE 140.A N PRO 136.A O no hydrogen 2.682 N/A VAL 141.A N ILE 137.A O no hydrogen 3.035 N/A SER 142.A N ALA 138.A O no hydrogen 2.682 N/A SER 142.A OG ALA 270.A O no hydrogen 2.558 N/A VAL 143.A N VAL 139.A O no hydrogen 2.807 N/A PHE 144.A N PHE 140.A O no hydrogen 2.812 N/A LEU 145.A N VAL 141.A O no hydrogen 2.927 N/A ILE 146.A N VAL 141.A O no hydrogen 3.052 N/A TYR 147.A N SER 142.A O no hydrogen 3.167 N/A TYR 147.A OH HIS 176.A NE2 no hydrogen 2.992 N/A LEU 149.A N LEU 145.A O no hydrogen 2.826 N/A GLY 150.A N ILE 146.A O no hydrogen 2.980 N/A GLN 151.A N TYR 147.A O no hydrogen 3.213 N/A TRP 154.A N GLY 73.A O no hydrogen 3.155 N/A ALA 157.A N TRP 154.A O no hydrogen 2.907 N/A PHE 160.A N VAL 65.A O no hydrogen 3.157 N/A GLY 161.A N SER 159.A O no hydrogen 2.978 N/A ALA 163.A N LEU 61.A O no hydrogen 3.329 N/A ILE 165.A N VAL 162.A O no hydrogen 2.807 N/A PHE 166.A N VAL 162.A O no hydrogen 3.305 N/A ARG 167.A N ALA 163.A O no hydrogen 2.897 N/A ARG 167.A NE ASP 320.A OD2 no hydrogen 3.404 N/A ARG 167.A NH2 ASP 320.A OD1 no hydrogen 3.201 N/A LEU 169.A N ILE 165.A O no hydrogen 2.987 N/A LEU 170.A N PHE 166.A O no hydrogen 3.104 N/A PHE 171.A N ARG 167.A O no hydrogen 2.966 N/A PHE 172.A N PHE 168.A O no hydrogen 3.029 N/A GLN 173.A N LEU 169.A O no hydrogen 3.118 N/A GLY 174.A N LEU 170.A O no hydrogen 3.080 N/A GLY 174.A N PHE 171.A O no hydrogen 3.191 N/A PHE 175.A N PHE 171.A O no hydrogen 3.220 N/A HIS 176.A N PHE 172.A O no hydrogen 2.923 N/A ASN 177.A N GLN 173.A O no hydrogen 3.263 N/A LEU 180.A N ASN 177.A O no hydrogen 3.035 N/A ASN 181.A N TRP 178.A O no hydrogen 2.989 N/A PHE 183.A N ASN 181.A OD1 no hydrogen 3.218 N/A MET 186.A N PRO 182.A O no hydrogen 2.988 N/A GLY 187.A N PHE 183.A O no hydrogen 3.027 N/A VAL 188.A N HIS 184.A O no hydrogen 2.743 N/A ALA 189.A N MET 186.A O no hydrogen 2.507 N/A GLY 190.A N MET 186.A O no hydrogen 3.007 N/A VAL 191.A N GLY 187.A O no hydrogen 3.215 N/A GLY 193.A N ALA 189.A O no hydrogen 2.788 N/A GLY 194.A N GLY 190.A O no hydrogen 2.584 N/A ALA 195.A N VAL 191.A O no hydrogen 3.326 N/A LEU 196.A N LEU 192.A O no hydrogen 3.087 N/A LEU 197.A N GLY 193.A O no hydrogen 2.991 N/A CYS 198.A N GLY 194.A O no hydrogen 2.987 N/A ALA 199.A N ALA 195.A O no hydrogen 3.275 N/A ALA 199.A N LEU 196.A O no hydrogen 3.360 N/A ILE 200.A N LEU 196.A O no hydrogen 3.181 N/A HIS 201.A N LEU 197.A O no hydrogen 2.831 N/A ALA 203.A N ALA 199.A O no hydrogen 2.707 N/A THR 204.A N ILE 200.A O no hydrogen 2.767 N/A THR 204.A OG1 ILE 200.A O no hydrogen 3.129 N/A VAL 205.A N HIS 201.A O no hydrogen 2.998 N/A ASN 207.A N ALA 203.A O no hydrogen 2.916 N/A THR 208.A N THR 204.A O no hydrogen 2.814 N/A THR 208.A N VAL 205.A O no hydrogen 2.490 N/A THR 208.A OG1 THR 204.A O no hydrogen 3.346 N/A PHE 210.A N THR 230.A O no hydrogen 2.654 N/A SER 217.A OG GLU 214.A O no hydrogen 3.210 N/A SER 217.A OG GLY 215.A O no hydrogen 2.956 N/A ALA 227.A N THR 225.A O no hydrogen 2.202 N/A THR 235.A N SER 232.A OG no hydrogen 3.316 N/A ALA 236.A N SER 232.A O no hydrogen 3.481 N/A ASN 237.A N MET 233.A O no hydrogen 2.920 N/A ARG 238.A N VAL 234.A O no hydrogen 3.407 N/A PHE 239.A N THR 235.A O no hydrogen 2.834 N/A TRP 240.A N ALA 236.A O no hydrogen 2.772 N/A SER 241.A N ASN 237.A O no hydrogen 2.688 N/A GLN 242.A N ARG 238.A O no hydrogen 2.914 N/A ILE 243.A N PHE 239.A O no hydrogen 2.923 N/A ILE 243.A N TRP 240.A O no hydrogen 2.692 N/A PHE 244.A N TRP 240.A O no hydrogen 2.560 N/A GLY 245.A N TRP 240.A O no hydrogen 3.008 N/A SER 249.A OG ALA 247.A O no hydrogen 3.065 N/A TRP 253.A N ASN 250.A O no hydrogen 2.682 N/A HIS 255.A N LYS 251.A O no hydrogen 3.218 N/A HIS 255.A ND1 LYS 251.A O no hydrogen 2.691 N/A PHE 256.A N ARG 252.A O no hydrogen 3.371 N/A PHE 257.A N TRP 253.A O no hydrogen 2.813 N/A MET 258.A N HIS 255.A O no hydrogen 2.931 N/A LEU 259.A N PHE 256.A O no hydrogen 2.406 N/A PHE 260.A N PHE 256.A O no hydrogen 3.027 N/A VAL 261.A N PHE 257.A O no hydrogen 3.202 N/A VAL 263.A N LEU 259.A O no hydrogen 3.279 N/A THR 264.A N PHE 260.A O no hydrogen 2.711 N/A THR 264.A OG1 PHE 260.A O no hydrogen 2.549 N/A GLY 265.A N VAL 261.A O no hydrogen 3.202 N/A LEU 266.A N PRO 262.A O no hydrogen 3.310 N/A TRP 267.A N VAL 263.A O no hydrogen 3.375 N/A SER 269.A N GLY 265.A O no hydrogen 3.259 N/A ALA 270.A N LEU 266.A O no hydrogen 2.981 N/A ILE 271.A N TRP 267.A O no hydrogen 2.908 N/A GLY 272.A N MET 268.A O no hydrogen 2.702 N/A VAL 273.A N SER 269.A O no hydrogen 3.187 N/A VAL 273.A N ALA 270.A O no hydrogen 3.195 N/A VAL 274.A N ALA 270.A O no hydrogen 3.177 N/A VAL 274.A N ILE 271.A O no hydrogen 2.646 N/A GLY 275.A N ILE 271.A O no hydrogen 3.226 N/A LEU 276.A N GLY 272.A O no hydrogen 3.426 N/A ALA 277.A N VAL 273.A O no hydrogen 3.025 N/A LEU 278.A N GLY 275.A O no hydrogen 2.931 N/A ASN 279.A N LEU 276.A O no hydrogen 2.576 N/A LEU 280.A N GLY 275.A O no hydrogen 3.368 N/A ARG 281.A NH2 ASN 279.A OD1 no hydrogen 2.976 N/A PHE 285.A N TYR 302.A OH no hydrogen 2.671 N/A GLN 288.A N PHE 285.A O no hydrogen 2.585 N/A GLU 289.A N PHE 285.A O no hydrogen 3.091 N/A ILE 290.A N ILE 286.A O no hydrogen 2.950 N/A ARG 291.A N SER 287.A O no hydrogen 3.522 N/A ALA 292.A N GLU 289.A O no hydrogen 2.582 N/A ALA 293.A N GLU 289.A O no hydrogen 2.968 N/A ALA 293.A N ILE 290.A O no hydrogen 3.156 N/A GLU 294.A N ILE 290.A O no hydrogen 3.177 N/A GLU 297.A N ASP 295.A OD1 no hydrogen 3.366 N/A THR 300.A OG1 GLN 288.A OE1 no hydrogen 3.259 N/A LYS 304.A N THR 300.A O no hydrogen 3.080 N/A ASN 305.A N PHE 301.A O no hydrogen 3.191 N/A LEU 306.A N TYR 302.A O no hydrogen 3.422 N/A LEU 307.A N THR 303.A O no hydrogen 3.346 N/A LEU 307.A N LYS 304.A O no hydrogen 3.256 N/A ASN 309.A N ASN 305.A O no hydrogen 3.163 N/A GLY 311.A N LEU 307.A O no hydrogen 3.305 N/A ILE 312.A N LEU 308.A O no hydrogen 2.918 N/A ARG 313.A N ASN 309.A O no hydrogen 2.759 N/A ALA 314.A N GLU 310.A O no hydrogen 2.799 N/A TRP 315.A N GLY 311.A O no hydrogen 3.315 N/A MET 316.A N ILE 312.A O no hydrogen 2.947 N/A ALA 317.A N ARG 313.A O no hydrogen 3.139 N/A ASP 320.A N MET 316.A O no hydrogen 3.301 N/A HIS 323.A ND1 ASN 70.A OD1 no hydrogen 2.392 N/A ARG 335.A NE LEU 339.A OXT no hydrogen 3.072 N/A ARG 335.A NH2 LEU 339.A OXT no hydrogen 3.148 N/A LEU 339.A N GLY 336.A O no hydrogen 3.385 N/A