Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 1sio_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): TYR 6.A N GLY 262.A O no hydrogen 2.791 N/A THR 7.A N ASP 10.A OD2 no hydrogen 2.856 N/A ASP 10.A N THR 7.A OG1 no hydrogen 3.116 N/A VAL 11.A N THR 7.A O no hydrogen 3.147 N/A ALA 12.A N PRO 8.A O no hydrogen 2.855 N/A GLN 13.A N LEU 9.A O no hydrogen 2.980 N/A ALA 14.A N ASP 10.A O no hydrogen 3.154 N/A TYR 15.A N VAL 11.A O no hydrogen 3.134 N/A TYR 15.A OH GLU 205.A OE2 no hydrogen 2.638 N/A GLN 16.A N GLN 13.A O no hydrogen 3.174 N/A PHE 17.A N ALA 12.A O no hydrogen 2.906 N/A GLY 23.A N GLN 293.A OE1 no hydrogen 2.860 N/A GLN 24.A N ASP 22.A OD1 no hydrogen 2.828 N/A GLN 26.A N GLY 23.A O no hydrogen 3.012 N/A CYS 27.A SG LYS 94.A O no hydrogen 3.492 N/A CYS 27.A SG LEU 120.A O no hydrogen 3.351 N/A ILE 28.A N LYS 94.A O no hydrogen 2.921 N/A ALA 29.A N VAL 124.A O no hydrogen 2.819 N/A ILE 30.A N ALA 96.A O no hydrogen 2.934 N/A ILE 31.A N SER 126.A O no hydrogen 3.099 N/A GLU 32.A N TYR 98.A O no hydrogen 2.816 N/A GLY 36.A N ASP 76.A OD1 no hydrogen 3.232 N/A TYR 37.A N ASN 66.A OD1 no hydrogen 2.671 N/A TYR 37.A OH SER 58.A OG no hydrogen 2.580 N/A ASP 38.A N GLU 80.A OE2 no hydrogen 3.112 N/A SER 41.A N ASP 38.A OD1 no hydrogen 2.798 N/A SER 41.A OG ASP 38.A OD1 no hydrogen 2.678 N/A SER 41.A OG GLU 80.A OE2 no hydrogen 3.553 N/A LEU 42.A N ASP 38.A O no hydrogen 3.361 N/A ALA 43.A N GLU 39.A O no hydrogen 2.997 N/A GLN 44.A N ALA 40.A O no hydrogen 2.989 N/A TYR 45.A N SER 41.A O no hydrogen 2.941 N/A PHE 46.A N LEU 42.A O no hydrogen 2.781 N/A ALA 47.A N ALA 43.A O no hydrogen 2.904 N/A SER 48.A N GLN 44.A O no hydrogen 2.945 N/A SER 48.A OG GLN 44.A O no hydrogen 3.000 N/A LEU 49.A N TYR 45.A O no hydrogen 2.819 N/A GLY 50.A N PHE 46.A O no hydrogen 2.775 N/A VAL 51.A N PHE 46.A O no hydrogen 3.115 N/A VAL 57.A N PHE 95.A O no hydrogen 2.863 N/A SER 58.A OG TYR 37.A OH no hydrogen 2.580 N/A VAL 59.A N VAL 97.A O no hydrogen 2.800 N/A SER 60.A OG ALA 64.A O no hydrogen 2.780 N/A VAL 61.A N PHE 99.A O no hydrogen 2.760 N/A ALA 64.A N VAL 61.A O no hydrogen 3.119 N/A ASN 66.A ND2 TYR 37.A O no hydrogen 3.124 N/A GLN 67.A N GLY 35.A O no hydrogen 3.324 N/A GLN 67.A NE2 ASN 66.A O no hydrogen 3.699 N/A THR 69.A N ASP 76.A OD1 no hydrogen 3.006 N/A GLY 70.A N ASP 76.A OD2 no hydrogen 2.963 N/A ASP 71.A N THR 69.A OG1 no hydrogen 3.363 N/A SER 73.A N ASP 71.A OD1 no hydrogen 2.992 N/A GLY 74.A N ASP 71.A O no hydrogen 2.713 N/A GLY 77.A N GLY 74.A O no hydrogen 3.107 N/A GLU 78.A N PRO 75.A O no hydrogen 2.848 N/A VAL 79.A N PRO 75.A O no hydrogen 2.903 N/A GLU 80.A N ASP 76.A O no hydrogen 2.960 N/A LEU 81.A N GLY 77.A O no hydrogen 3.246 N/A ASP 82.A N GLU 78.A O no hydrogen 2.999 N/A ILE 83.A N VAL 79.A O no hydrogen 3.119 N/A GLU 84.A N GLU 80.A O no hydrogen 2.837 N/A VAL 85.A N LEU 81.A O no hydrogen 3.006 N/A ALA 86.A N ASP 82.A O no hydrogen 3.193 N/A GLY 87.A N ILE 83.A O no hydrogen 2.717 N/A ALA 88.A N GLU 84.A O no hydrogen 2.958 N/A LEU 89.A N ALA 86.A O no hydrogen 3.250 N/A ALA 90.A N ALA 86.A O no hydrogen 2.927 N/A GLY 92.A N ASP 22.A O no hydrogen 2.710 N/A ALA 93.A N ALA 90.A O no hydrogen 2.901 N/A LYS 94.A N GLN 26.A O no hydrogen 2.913 N/A PHE 95.A N GLN 55.A O no hydrogen 2.872 N/A ALA 96.A N ILE 28.A O no hydrogen 2.942 N/A VAL 97.A N VAL 57.A O no hydrogen 2.705 N/A TYR 98.A N ILE 30.A O no hydrogen 3.066 N/A TYR 98.A OH ASP 117.A OD2 no hydrogen 3.043 N/A PHE 99.A N VAL 59.A O no hydrogen 3.033 N/A ALA 100.A N GLU 32.A O no hydrogen 3.035 N/A THR 103.A N PRO 101.A O no hydrogen 2.829 N/A GLY 106.A N THR 103.A OG1 no hydrogen 2.799 N/A PHE 107.A N THR 103.A O no hydrogen 2.803 N/A LEU 108.A N ASP 104.A O no hydrogen 3.062 N/A ASP 109.A N ALA 105.A O no hydrogen 2.850 N/A ALA 110.A N GLY 106.A O no hydrogen 2.935 N/A ILE 111.A N PHE 107.A O no hydrogen 3.108 N/A THR 112.A N LEU 108.A O no hydrogen 2.917 N/A THR 112.A OG1 LEU 108.A O no hydrogen 3.015 N/A THR 112.A OG1 ASP 109.A O no hydrogen 3.341 N/A THR 113.A N ASP 109.A O no hydrogen 2.795 N/A THR 113.A OG1 ASP 109.A O no hydrogen 2.832 N/A ALA 114.A N ALA 110.A O no hydrogen 3.012 N/A ILE 115.A N ILE 111.A O no hydrogen 3.038 N/A HIS 116.A N THR 112.A O no hydrogen 3.214 N/A HIS 116.A ND1 THR 112.A O no hydrogen 3.186 N/A ASP 117.A N ALA 114.A O no hydrogen 3.003 N/A THR 119.A N ASP 117.A OD1 no hydrogen 2.850 N/A LEU 120.A N ASP 117.A OD1 no hydrogen 2.772 N/A LYS 121.A N ASP 117.A O no hydrogen 2.985 N/A SER 123.A N CYS 27.A O no hydrogen 3.085 N/A SER 123.A OG GLN 26.A OE1 no hydrogen 3.059 N/A SER 123.A OG CYS 27.A O no hydrogen 3.470 N/A VAL 125.A N THR 157.A O no hydrogen 2.647 N/A SER 126.A N ALA 29.A O no hydrogen 2.801 N/A ILE 127.A N LEU 159.A O no hydrogen 2.845 N/A SER 128.A OG SER 278.A O no hydrogen 2.891 N/A TRP 129.A NE1 GLU 32.A OE1 no hydrogen 2.929 N/A GLY 131.A N PHE 180.A O no hydrogen 3.189 N/A GLU 133.A N VAL 178.A O no hydrogen 2.844 N/A SER 135.A N PRO 132.A O no hydrogen 2.834 N/A SER 135.A OG PRO 132.A O no hydrogen 2.717 N/A TRP 136.A N GLU 133.A O no hydrogen 3.321 N/A TRP 136.A NE1 GLY 131.A O no hydrogen 2.945 N/A ALA 140.A N THR 137.A OG1 no hydrogen 3.049 N/A ILE 141.A N THR 137.A O no hydrogen 2.976 N/A ALA 142.A N SER 138.A O no hydrogen 2.989 N/A ALA 143.A N ALA 139.A O no hydrogen 2.981 N/A MET 144.A N ALA 140.A O no hydrogen 2.957 N/A ASN 145.A N ILE 141.A O no hydrogen 2.920 N/A ARG 146.A N ALA 142.A O no hydrogen 3.031 N/A ALA 147.A N ALA 143.A O no hydrogen 3.010 N/A PHE 148.A N MET 144.A O no hydrogen 3.036 N/A LEU 149.A N ASN 145.A O no hydrogen 2.850 N/A ASP 150.A N ARG 146.A O no hydrogen 2.915 N/A ALA 151.A N ALA 147.A O no hydrogen 2.863 N/A ALA 152.A N PHE 148.A O no hydrogen 2.994 N/A ALA 153.A N LEU 149.A O no hydrogen 3.263 N/A LEU 154.A N ASP 150.A O no hydrogen 2.955 N/A GLY 155.A N ALA 152.A O no hydrogen 3.206 N/A VAL 156.A N ALA 151.A O no hydrogen 3.188 N/A THR 157.A N SER 123.A O no hydrogen 3.033 N/A THR 157.A OG1 GLY 300.A O no hydrogen 2.631 N/A LEU 159.A N VAL 125.A O no hydrogen 2.718 N/A ALA 160.A N LEU 188.A O no hydrogen 2.930 N/A ALA 161.A N ILE 127.A O no hydrogen 3.017 N/A ALA 162.A N CYS 190.A O no hydrogen 2.843 N/A GLY 163.A N THR 277.A OG1 no hydrogen 3.047 N/A GLY 166.A N ALA 216.A O no hydrogen 2.821 N/A SER 167.A N ASN 322.A O no hydrogen 2.880 N/A SER 167.A OG ASN 322.A O no hydrogen 3.566 N/A SER 167.A OG ILE 330.A O no hydrogen 2.693 N/A ASP 169.A N SER 165.A O no hydrogen 3.185 N/A ASP 169.A N GLY 166.A O no hydrogen 3.265 N/A GLU 171.A N THR 168.A O no hydrogen 3.116 N/A LEU 175.A N ASP 173.A OD1 no hydrogen 2.682 N/A TYR 176.A N ASN 241.A OD1 no hydrogen 2.885 N/A HIS 177.A N SER 167.A O no hydrogen 2.927 N/A HIS 177.A NE2 ASP 173.A OD1 no hydrogen 2.697 N/A PHE 180.A N GLY 131.A O no hydrogen 2.924 N/A SER 184.A N PRO 181.A O no hydrogen 2.994 N/A TYR 186.A N SER 184.A OG no hydrogen 3.169 N/A VAL 187.A N SER 184.A O no hydrogen 3.251 N/A LEU 188.A N VAL 158.A O no hydrogen 2.820 N/A ALA 189.A N ASP 252.A OD2 no hydrogen 2.890 N/A CYS 190.A N ALA 160.A O no hydrogen 2.846 N/A CYS 190.A SG LEU 188.A O no hydrogen 3.563 N/A GLY 191.A N LEU 253.A O no hydrogen 2.777 N/A GLY 192.A N THR 217.A OG1 no hydrogen 2.835 N/A THR 193.A N GLY 255.A O no hydrogen 2.950 N/A THR 193.A OG1 GLU 205.A OE2 no hydrogen 2.720 N/A ARG 194.A N THR 206.A O no hydrogen 2.826 N/A LEU 195.A N ASN 256.A OD1 no hydrogen 3.047 N/A LEU 195.A N THR 261.A OG1 no hydrogen 3.341 N/A VAL 196.A N GLN 204.A O no hydrogen 2.682 N/A ALA 197.A N TYR 6.A OH no hydrogen 2.882 N/A SER 198.A N ARG 201.A O no hydrogen 2.769 N/A ARG 201.A N SER 198.A O no hydrogen 3.006 N/A ALA 203.A N VAL 196.A O no hydrogen 2.739 N/A GLN 204.A N VAL 196.A O no hydrogen 3.114 N/A THR 206.A N ARG 194.A O no hydrogen 3.142 N/A VAL 207.A N GLU 319.A O no hydrogen 3.034 N/A TRP 208.A N GLY 192.A O no hydrogen 3.008 N/A TRP 208.A NE1 ASP 210.A OD2 no hydrogen 3.150 N/A ASN 209.A ND2 ASN 321.A O no hydrogen 2.937 N/A ASN 209.A ND2 ASN 321.A OD1 no hydrogen 3.210 N/A ASN 209.A ND2 ASP 323.A O no hydrogen 3.089 N/A ASP 210.A N GLY 215.A O no hydrogen 2.649 N/A GLY 211.A N ASN 209.A OD1 no hydrogen 2.769 N/A GLY 214.A N GLY 211.A O no hydrogen 3.051 N/A GLY 215.A N GLY 211.A O no hydrogen 2.930 N/A ALA 216.A N ASP 164.A O no hydrogen 3.171 N/A THR 217.A N TRP 208.A O no hydrogen 2.924 N/A THR 217.A OG1 GLY 218.A O no hydrogen 2.977 N/A GLY 218.A N GLY 163.A O no hydrogen 2.929 N/A GLY 220.A N VAL 250.A O no hydrogen 2.864 N/A SER 222.A N ARG 248.A O no hydrogen 2.747 N/A SER 222.A OG GLU 133.A OE1 no hydrogen 3.359 N/A SER 222.A OG GLU 133.A OE2 no hydrogen 2.671 N/A ARG 223.A N GLU 133.A OE1 no hydrogen 2.760 N/A ILE 224.A N SER 222.A OG no hydrogen 3.203 N/A PHE 225.A N SER 222.A OG no hydrogen 2.909 N/A GLN 231.A N PRO 228.A O no hydrogen 2.762 N/A GLN 231.A NE2 GLY 249.A O no hydrogen 2.971 N/A GLN 231.A NE2 TYR 307.A OH no hydrogen 3.080 N/A GLU 232.A N ALA 229.A O no hydrogen 2.948 N/A ALA 234.A N GLN 231.A O no hydrogen 3.019 N/A SER 239.A N SER 245.A O no hydrogen 3.028 N/A ALA 240.A N TYR 331.A OH no hydrogen 2.965 N/A ASN 241.A N SER 239.A OG no hydrogen 2.944 N/A ASN 241.A ND2 TYR 176.A O no hydrogen 2.975 N/A ALA 244.A N ASN 241.A O no hydrogen 2.637 N/A ARG 248.A N PHE 225.A O no hydrogen 2.905 N/A ARG 248.A NE ALA 183.A O no hydrogen 2.890 N/A ARG 248.A NE SER 184.A O no hydrogen 3.289 N/A ARG 248.A NH1 GLY 249.A O no hydrogen 2.823 N/A ARG 248.A NH1 ASP 252.A OD1 no hydrogen 2.958 N/A ARG 248.A NH1 ASP 252.A OD2 no hydrogen 3.424 N/A ARG 248.A NH2 SER 184.A O no hydrogen 2.942 N/A ARG 248.A NH2 ASP 252.A OD2 no hydrogen 2.976 N/A GLY 249.A N GLN 231.A OE1 no hydrogen 2.897 N/A VAL 250.A N GLY 220.A O no hydrogen 2.726 N/A ASP 252.A N ALA 189.A O no hydrogen 2.950 N/A LEU 253.A N ALA 189.A O no hydrogen 3.243 N/A ALA 254.A N GLY 344.A O no hydrogen 3.040 N/A GLY 255.A N GLY 191.A O no hydrogen 2.962 N/A ASN 256.A N TYR 15.A OH no hydrogen 2.690 N/A ASN 256.A ND2 THR 261.A O no hydrogen 2.780 N/A ALA 257.A N THR 193.A O no hydrogen 2.844 N/A ASP 258.A N THR 193.A O no hydrogen 3.128 N/A ALA 260.A N ASP 258.A OD1 no hydrogen 2.992 N/A THR 261.A N ASP 258.A O no hydrogen 2.841 N/A THR 261.A OG1 ASN 256.A OD1 no hydrogen 2.773 N/A THR 261.A OG1 ASP 258.A O no hydrogen 3.453 N/A TYR 263.A N ILE 274.A O no hydrogen 2.736 N/A TYR 263.A OH ASN 256.A O no hydrogen 2.719 N/A GLU 264.A N TYR 6.A O no hydrogen 2.779 N/A VAL 265.A N THR 272.A O no hydrogen 3.032 N/A VAL 266.A N GLU 84.A OE1 no hydrogen 2.955 N/A ILE 267.A N GLU 270.A O no hydrogen 3.032 N/A ASP 268.A N GLU 80.A OE1 no hydrogen 2.931 N/A GLY 269.A N SER 41.A OG no hydrogen 2.735 N/A GLU 270.A N ILE 267.A O no hydrogen 3.025 N/A THR 272.A N VAL 265.A O no hydrogen 2.904 N/A ILE 274.A N TYR 263.A O no hydrogen 3.163 N/A GLY 276.A N ALA 257.A O no hydrogen 2.482 N/A THR 277.A N ASP 164.A OD1 no hydrogen 2.934 N/A THR 277.A OG1 GLY 163.A O no hydrogen 3.078 N/A THR 277.A OG1 ASP 164.A OD1 no hydrogen 2.950 N/A SER 278.A OG GLU 78.A OE1 no hydrogen 2.578 N/A SER 278.A OG SER 128.A O no hydrogen 3.424 N/A ALA 279.A N GLY 276.A O no hydrogen 2.979 N/A VAL 280.A N THR 277.A O no hydrogen 2.766 N/A LEU 283.A N ALA 279.A O no hydrogen 3.223 N/A PHE 284.A N VAL 280.A O no hydrogen 3.030 N/A ALA 285.A N ALA 281.A O no hydrogen 2.832 N/A ALA 286.A N PRO 282.A O no hydrogen 3.126 N/A LEU 287.A N LEU 283.A O no hydrogen 3.283 N/A VAL 288.A N PHE 284.A O no hydrogen 2.730 N/A ALA 289.A N ALA 285.A O no hydrogen 2.931 N/A ARG 290.A N ALA 286.A O no hydrogen 3.021 N/A ARG 290.A NE LEU 89.A O no hydrogen 2.865 N/A ARG 290.A NH1 PRO 18.A O no hydrogen 2.825 N/A ARG 290.A NH2 LEU 89.A O no hydrogen 2.757 N/A ILE 291.A N LEU 287.A O no hydrogen 3.061 N/A ASN 292.A N VAL 288.A O no hydrogen 2.817 N/A ASN 292.A ND2 GLN 26.A OE1 no hydrogen 3.579 N/A GLN 293.A N ALA 289.A O no hydrogen 2.938 N/A LYS 294.A N ARG 290.A O no hydrogen 3.031 N/A LEU 295.A N ILE 291.A O no hydrogen 2.805 N/A GLY 296.A N ASN 292.A O no hydrogen 2.898 N/A VAL 299.A N ASN 292.A OD1 no hydrogen 2.936 N/A TYR 301.A OH PRO 185.A O no hydrogen 2.687 N/A LEU 306.A N LEU 302.A O no hydrogen 3.137 N/A TYR 307.A N PRO 304.A O no hydrogen 3.273 N/A TYR 307.A OH ASP 252.A OD1 no hydrogen 2.441 N/A GLN 308.A N THR 305.A O no hydrogen 2.981 N/A LEU 309.A N LEU 306.A O no hydrogen 3.254 N/A VAL 313.A N PRO 310.A O no hydrogen 3.059 N/A PHE 314.A N ALA 311.A O no hydrogen 3.162 N/A HIS 315.A N SER 345.A O no hydrogen 2.796 N/A ASN 322.A N TYR 331.A O no hydrogen 2.878 N/A ASN 322.A ND2 THR 217.A O no hydrogen 2.926 N/A ASN 322.A ND2 GLY 219.A O no hydrogen 3.416 N/A ASP 323.A N ASN 321.A OD1 no hydrogen 2.967 N/A ALA 325.A N ASP 323.A OD1 no hydrogen 3.020 N/A ASN 326.A N ASP 323.A OD1 no hydrogen 3.133 N/A ASN 326.A ND2 TYR 176.A OH no hydrogen 2.979 N/A ALA 328.A N ASN 326.A OD1 no hydrogen 2.626 N/A ILE 330.A N ASP 323.A OD2 no hydrogen 3.134 N/A TYR 331.A N ASN 322.A OD1 no hydrogen 2.857 N/A ALA 333.A N GLY 320.A O no hydrogen 2.860 N/A GLY 334.A N ASP 338.A OD2 no hydrogen 3.153 N/A GLY 336.A N ASP 316.A OD2 no hydrogen 2.741 N/A TRP 337.A NE1 PRO 251.A O no hydrogen 3.129 N/A ASP 338.A N GLY 342.A O no hydrogen 3.167 N/A CYS 340.A N ASP 338.A OD1 no hydrogen 3.071 N/A CYS 340.A SG ASN 322.A OD1 no hydrogen 3.641 N/A CYS 340.A SG TYR 331.A O no hydrogen 3.032 N/A THR 341.A N ASP 338.A OD1 no hydrogen 2.892 N/A THR 341.A OG1 ASP 338.A OD1 no hydrogen 2.891 N/A GLY 342.A N ASP 338.A O no hydrogen 2.943 N/A LEU 343.A N ASP 252.A O no hydrogen 2.959 N/A GLY 344.A N THR 341.A O no hydrogen 2.950 N/A SER 345.A N HIS 315.A O no hydrogen 2.969 N/A SER 345.A OG GLU 205.A OE1 no hydrogen 2.879 N/A ILE 347.A N VAL 313.A O no hydrogen 2.858 N/A GLY 348.A N TYR 15.A O no hydrogen 2.856 N/A ARG 350.A NH1 ASP 312.A O no hydrogen 2.777 N/A LEU 351.A N ILE 347.A O no hydrogen 2.884 N/A LEU 352.A N GLY 348.A O no hydrogen 3.057 N/A GLN 353.A N VAL 349.A O no hydrogen 3.077 N/A ALA 354.A N ARG 350.A O no hydrogen 3.001 N/A LEU 355.A N LEU 351.A O no hydrogen 3.125 N/A LEU 355.A N LEU 352.A O no hydrogen 2.899 N/A LEU 356.A N GLN 353.A O no hydrogen 3.192 N/A