Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 1t2f_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ALA 1.A N THR 2.A O no hydrogen 3.396 N/A LYS 4.A N THR 2.A OG1 no hydrogen 3.343 N/A GLU 5.A N THR 2.A O no hydrogen 3.283 N/A ILE 8.A N LYS 4.A O no hydrogen 3.349 N/A GLU 15.A N GLU 14.A OE1 no hydrogen 3.178 N/A ALA 16.A N GLU 15.A OE2 no hydrogen 3.301 N/A ASN 20.A N ASP 46.A OD2 no hydrogen 3.263 N/A LYS 22.A N ASN 20.A O no hydrogen 3.018 N/A LYS 22.A NZ VAL 85.A O no hydrogen 2.085 N/A LYS 22.A NZ ALA 87.A O no hydrogen 2.387 N/A ILE 23.A N GLU 47.A O no hydrogen 2.934 N/A THR 24.A N ILE 91.A O no hydrogen 3.009 N/A THR 24.A OG1 SER 89.A OG no hydrogen 2.772 N/A VAL 25.A N ALA 49.A O no hydrogen 2.666 N/A VAL 26.A N VAL 93.A O no hydrogen 2.887 N/A GLY 27.A N VAL 51.A O no hydrogen 2.921 N/A VAL 28.A N ASP 52.A OD2 no hydrogen 2.896 N/A MET 33.A N GLY 29.A O no hydrogen 2.815 N/A ALA 34.A N GLN 30.A O no hydrogen 3.056 N/A CYS 35.A N VAL 31.A O no hydrogen 3.085 N/A CYS 35.A SG VAL 31.A O no hydrogen 3.960 N/A ALA 36.A N GLY 32.A O no hydrogen 3.164 N/A ILE 37.A N MET 33.A O no hydrogen 2.690 N/A SER 38.A N ALA 34.A O no hydrogen 3.099 N/A SER 38.A OG ALA 34.A O no hydrogen 3.217 N/A ILE 39.A N CYS 35.A O no hydrogen 3.034 N/A LEU 40.A N ALA 36.A O no hydrogen 2.956 N/A GLY 41.A N ILE 37.A O no hydrogen 3.088 N/A LYS 42.A N SER 38.A O no hydrogen 3.330 N/A LYS 42.A NZ GLU 261.A OE1 no hydrogen 2.388 N/A SER 43.A N ILE 39.A O no hydrogen 3.160 N/A SER 43.A OG GLY 41.A O no hydrogen 3.492 N/A SER 43.A OG GLN 73.A OE1 no hydrogen 3.091 N/A LEU 44.A N ILE 39.A O no hydrogen 3.153 N/A ASP 46.A N ASN 21.A O no hydrogen 3.354 N/A LEU 48.A N LYS 76.A O no hydrogen 2.971 N/A ALA 49.A N ILE 23.A O no hydrogen 3.016 N/A LEU 50.A N VAL 78.A O no hydrogen 3.067 N/A VAL 51.A N VAL 25.A O no hydrogen 3.211 N/A VAL 53.A N ASP 52.A OD1 no hydrogen 2.665 N/A LEU 54.A N ASP 52.A OD1 no hydrogen 3.257 N/A GLU 55.A N VAL 53.A O no hydrogen 2.803 N/A LYS 57.A NZ VAL 28.A O no hydrogen 2.371 N/A LYS 57.A NZ GLU 61.A OE2 no hydrogen 3.027 N/A LEU 58.A N LEU 54.A O no hydrogen 2.993 N/A LYS 59.A N GLU 55.A O no hydrogen 3.424 N/A GLY 60.A N ASP 56.A O no hydrogen 2.806 N/A GLU 61.A N LYS 57.A O no hydrogen 2.618 N/A MET 62.A N LEU 58.A O no hydrogen 2.991 N/A MET 63.A N LYS 59.A O no hydrogen 3.183 N/A ASP 64.A N GLY 60.A O no hydrogen 3.053 N/A LEU 65.A N GLU 61.A O no hydrogen 3.121 N/A GLN 66.A N MET 62.A O no hydrogen 2.828 N/A GLN 66.A NE2 ILE 77.A O no hydrogen 2.710 N/A HIS 67.A N MET 63.A O no hydrogen 3.051 N/A SER 69.A N GLN 66.A O no hydrogen 2.843 N/A SER 69.A OG GLN 66.A O no hydrogen 3.086 N/A PHE 71.A N GLY 68.A O no hydrogen 2.826 N/A LEU 72.A N SER 69.A O no hydrogen 3.174 N/A THR 74.A OG1 ALA 45.A O no hydrogen 2.803 N/A VAL 78.A N LEU 48.A O no hydrogen 3.205 N/A ASP 80.A N LEU 50.A O no hydrogen 3.251 N/A SER 84.A N ASP 82.A OD1 no hydrogen 3.363 N/A SER 84.A OG ASP 82.A OD1 no hydrogen 1.997 N/A VAL 85.A N ASP 82.A O no hydrogen 3.064 N/A THR 86.A OG1 TYR 83.A O no hydrogen 2.787 N/A ASN 88.A N TYR 127.A O no hydrogen 3.173 N/A SER 89.A OG THR 24.A OG1 no hydrogen 2.772 N/A SER 89.A OG THR 86.A O no hydrogen 2.403 N/A LYS 90.A N LYS 22.A O no hydrogen 3.008 N/A LYS 90.A NZ ASN 20.A OD1 no hydrogen 3.556 N/A VAL 92.A N ILE 132.A O no hydrogen 2.973 N/A VAL 93.A N THR 24.A O no hydrogen 2.838 N/A VAL 94.A N ILE 134.A O no hydrogen 2.701 N/A THR 95.A N VAL 26.A O no hydrogen 2.762 N/A THR 95.A OG1 VAL 26.A O no hydrogen 2.643 N/A THR 95.A OG1 GLY 27.A O no hydrogen 3.194 N/A VAL 98.A N ASN 113.A OD1 no hydrogen 2.743 N/A GLN 101.A N GLU 104.A OE1 no hydrogen 3.377 N/A GLU 104.A N GLN 101.A O no hydrogen 2.608 N/A LEU 107.A N SER 105.A OG no hydrogen 3.144 N/A ASN 108.A N SER 105.A O no hydrogen 3.018 N/A LEU 109.A N ARG 106.A O no hydrogen 3.385 N/A ARG 112.A NH2 GLU 104.A OE2 no hydrogen 3.056 N/A ARG 112.A NH2 ASN 108.A O no hydrogen 3.222 N/A ASN 113.A N LEU 109.A O no hydrogen 2.996 N/A ASN 113.A ND2 VAL 98.A O no hydrogen 3.181 N/A ASN 113.A ND2 ASN 138.A O no hydrogen 2.452 N/A VAL 114.A N VAL 110.A O no hydrogen 2.851 N/A ASN 115.A N GLN 111.A O no hydrogen 3.296 N/A ASN 115.A N ARG 112.A O no hydrogen 3.118 N/A VAL 116.A N ASN 113.A O no hydrogen 3.335 N/A PHE 117.A N ASN 113.A O no hydrogen 3.027 N/A PHE 119.A N VAL 116.A O no hydrogen 2.927 N/A ILE 121.A N PHE 117.A O no hydrogen 3.308 N/A GLN 123.A NE2 PHE 119.A O no hydrogen 2.979 N/A ILE 124.A N ILE 120.A O no hydrogen 3.313 N/A VAL 125.A N ILE 121.A O no hydrogen 3.147 N/A LYS 126.A N PRO 122.A O no hydrogen 3.090 N/A SER 128.A N VAL 125.A O no hydrogen 3.345 N/A SER 128.A OG THR 86.A O no hydrogen 3.427 N/A SER 128.A OG ILE 124.A O no hydrogen 2.999 N/A CYS 131.A SG SER 128.A O no hydrogen 2.978 N/A ILE 132.A N LYS 90.A O no hydrogen 3.450 N/A ILE 133.A N ARG 157.A O no hydrogen 3.080 N/A ILE 134.A N VAL 92.A O no hydrogen 2.870 N/A VAL 135.A N ILE 159.A O no hydrogen 3.096 N/A VAL 136.A N VAL 94.A O no hydrogen 3.302 N/A SER 137.A N VAL 94.A O no hydrogen 3.279 N/A SER 137.A OG VAL 94.A O no hydrogen 2.826 N/A SER 137.A OG ALA 96.A O no hydrogen 2.386 N/A LEU 143.A N PRO 139.A O no hydrogen 3.159 N/A THR 144.A N VAL 140.A O no hydrogen 2.875 N/A THR 144.A OG1 VAL 140.A O no hydrogen 2.987 N/A TYR 145.A N ASP 141.A O no hydrogen 3.258 N/A VAL 146.A N ILE 142.A O no hydrogen 2.811 N/A THR 147.A N THR 144.A O no hydrogen 3.047 N/A TRP 148.A N THR 144.A O no hydrogen 2.918 N/A LYS 149.A N TYR 145.A O no hydrogen 3.195 N/A LYS 149.A NZ GLU 286.A OE1 no hydrogen 3.177 N/A LYS 149.A NZ GLU 286.A OE2 no hydrogen 3.539 N/A LEU 150.A N VAL 146.A O no hydrogen 3.434 N/A SER 151.A N THR 147.A O no hydrogen 2.981 N/A SER 151.A OG THR 147.A O no hydrogen 3.017 N/A SER 151.A OG TRP 148.A O no hydrogen 3.505 N/A LEU 153.A N SER 151.A OG no hydrogen 3.074 N/A ARG 157.A N PRO 154.A O no hydrogen 3.192 N/A ARG 157.A NH2 PRO 129.A O no hydrogen 3.474 N/A VAL 158.A N LYS 155.A O no hydrogen 3.478 N/A ILE 159.A N ILE 133.A O no hydrogen 2.977 N/A GLY 160.A N SER 274.A O no hydrogen 3.259 N/A SER 161.A N VAL 135.A O no hydrogen 2.952 N/A CYS 163.A SG GLY 191.A O no hydrogen 3.967 N/A CYS 163.A SG SER 290.A OG no hydrogen 2.890 N/A ASN 164.A N SER 161.A O no hydrogen 3.310 N/A SER 167.A N CYS 163.A O no hydrogen 3.064 N/A SER 167.A OG CYS 163.A O no hydrogen 3.336 N/A SER 167.A OG ILE 189.A O no hydrogen 2.951 N/A ALA 168.A N ASN 164.A O no hydrogen 3.203 N/A ARG 169.A N LEU 165.A O no hydrogen 3.062 N/A PHE 170.A N ASP 166.A O no hydrogen 2.939 N/A ARG 171.A N SER 167.A O no hydrogen 3.025 N/A ARG 171.A NE PRO 182.A O no hydrogen 3.381 N/A ARG 171.A NE CYS 185.A O no hydrogen 2.850 N/A ARG 171.A NH2 PRO 182.A O no hydrogen 3.528 N/A ARG 171.A NH2 SER 183.A O no hydrogen 2.932 N/A ARG 171.A NH2 CYS 185.A O no hydrogen 3.020 N/A TYR 172.A N ALA 168.A O no hydrogen 3.053 N/A LEU 173.A N ARG 169.A O no hydrogen 2.745 N/A MET 174.A N PHE 170.A O no hydrogen 2.824 N/A ALA 175.A N ARG 171.A O no hydrogen 3.041 N/A GLU 176.A N TYR 172.A O no hydrogen 2.898 N/A LYS 177.A N LEU 173.A O no hydrogen 3.253 N/A LEU 178.A N MET 174.A O no hydrogen 3.271 N/A LEU 178.A N ALA 175.A O no hydrogen 2.771 N/A GLY 179.A N ALA 175.A O no hydrogen 2.811 N/A SER 184.A N HIS 181.A O no hydrogen 2.904 N/A CYS 185.A N HIS 181.A O no hydrogen 3.182 N/A CYS 185.A SG HIS 181.A O no hydrogen 3.737 N/A HIS 186.A N ASN 205.A O no hydrogen 3.170 N/A ILE 189.A N SER 167.A OG no hydrogen 2.874 N/A LEU 190.A N VAL 198.A O no hydrogen 2.962 N/A GLY 191.A N SER 290.A O no hydrogen 3.197 N/A GLU 192.A N SER 319.A OG no hydrogen 2.825 N/A HIS 193.A N ASP 141.A OD2 no hydrogen 3.213 N/A HIS 193.A ND1 ASP 166.A OD2 no hydrogen 2.456 N/A SER 196.A N GLU 192.A OE1 no hydrogen 3.395 N/A SER 196.A OG GLU 192.A OE1 no hydrogen 2.896 N/A SER 196.A OG SER 319.A OG no hydrogen 2.754 N/A VAL 198.A N LEU 190.A O no hydrogen 2.724 N/A VAL 200.A N TRP 188.A O no hydrogen 3.197 N/A SER 202.A N GLU 312.A OE2 no hydrogen 3.054 N/A GLY 203.A N VAL 200.A O no hydrogen 3.250 N/A ASN 205.A N HIS 186.A O no hydrogen 3.103 N/A VAL 206.A N VAL 209.A O no hydrogen 3.181 N/A VAL 209.A N VAL 206.A O no hydrogen 3.033 N/A LEU 211.A N VAL 204.A O no hydrogen 3.350 N/A LEU 214.A N SER 210.A O no hydrogen 3.030 N/A ASN 215.A N GLN 212.A O no hydrogen 2.959 N/A ASN 226.A N SER 224.A OG no hydrogen 3.328 N/A TRP 227.A N SER 224.A OG no hydrogen 3.053 N/A LYS 228.A NZ ASP 221.A OD2 no hydrogen 2.862 N/A VAL 230.A N TRP 227.A O no hydrogen 2.770 N/A HIS 231.A NE2 SER 197.A O no hydrogen 3.013 N/A LYS 232.A N LYS 228.A O no hydrogen 3.144 N/A MET 233.A N GLU 229.A O no hydrogen 3.238 N/A VAL 234.A N VAL 230.A O no hydrogen 2.781 N/A VAL 235.A N HIS 231.A O no hydrogen 3.170 N/A GLU 236.A N LYS 232.A O no hydrogen 3.316 N/A SER 237.A OG MET 233.A O no hydrogen 3.333 N/A SER 237.A OG VAL 234.A O no hydrogen 2.492 N/A TYR 239.A OH ASP 195.A OD1 no hydrogen 2.403 N/A GLU 240.A N GLU 236.A O no hydrogen 2.679 N/A VAL 241.A N SER 237.A O no hydrogen 3.142 N/A VAL 241.A N ALA 238.A O no hydrogen 3.070 N/A ILE 242.A N ALA 238.A O no hydrogen 2.804 N/A LEU 244.A N VAL 241.A O no hydrogen 3.140 N/A LYS 245.A N VAL 241.A O no hydrogen 2.958 N/A LYS 245.A NZ ASN 249.A OD1 no hydrogen 3.170 N/A GLY 246.A N ILE 242.A O no hydrogen 2.626 N/A ASN 249.A ND2 GLN 30.A O no hydrogen 2.652 N/A GLY 253.A N ASN 249.A O no hydrogen 2.713 N/A LEU 254.A N TRP 250.A O no hydrogen 2.915 N/A SER 255.A N ALA 251.A O no hydrogen 2.881 N/A SER 255.A OG ASN 164.A OD1 no hydrogen 3.101 N/A VAL 256.A N ILE 252.A O no hydrogen 3.050 N/A ASP 258.A N LEU 254.A O no hydrogen 3.335 N/A ASP 258.A N SER 255.A O no hydrogen 2.491 N/A LEU 259.A N SER 255.A O no hydrogen 3.058 N/A ILE 260.A N VAL 256.A O no hydrogen 3.446 N/A GLU 261.A N ALA 257.A O no hydrogen 2.843 N/A SER 262.A N ASP 258.A O no hydrogen 3.213 N/A SER 262.A OG ASP 258.A O no hydrogen 2.974 N/A MET 263.A N LEU 259.A O no hydrogen 3.047 N/A LEU 264.A N ILE 260.A O no hydrogen 2.960 N/A LYS 265.A N GLU 261.A O no hydrogen 3.027 N/A ASN 266.A N MET 263.A O no hydrogen 2.888 N/A LEU 267.A N SER 262.A O no hydrogen 3.136 N/A HIS 271.A N CYS 293.A O no hydrogen 2.950 N/A VAL 273.A N LEU 291.A O no hydrogen 3.206 N/A SER 274.A N GLY 160.A O no hydrogen 3.297 N/A THR 275.A N LEU 289.A O no hydrogen 2.809 N/A VAL 277.A N VAL 287.A O no hydrogen 2.804 N/A GLY 279.A N ILE 283.A O no hydrogen 2.752 N/A MET 280.A N VAL 277.A O no hydrogen 3.101 N/A LEU 289.A N THR 275.A O no hydrogen 3.456 N/A SER 290.A N GLY 191.A O no hydrogen 3.215 N/A SER 290.A OG GLY 191.A O no hydrogen 2.790 N/A LEU 291.A N VAL 273.A O no hydrogen 2.965 N/A CYS 293.A N HIS 271.A O no hydrogen 3.055 N/A CYS 293.A SG VAL 273.A O no hydrogen 3.852 N/A CYS 293.A SG LEU 291.A O no hydrogen 2.815 N/A ILE 294.A N SER 302.A O no hydrogen 2.785 N/A LEU 295.A N ARG 269.A O no hydrogen 3.131 N/A ASN 296.A N GLY 299.A O no hydrogen 2.680 N/A ARG 298.A N ASN 296.A OD1 no hydrogen 2.652 N/A GLY 299.A N ASN 296.A O no hydrogen 3.374 N/A GLY 299.A N ASN 296.A OD1 no hydrogen 3.090 N/A LEU 300.A N HIS 156.A O no hydrogen 2.924 N/A THR 301.A N ILE 294.A O no hydrogen 2.875 N/A THR 301.A OG1 ILE 294.A O no hydrogen 3.158 N/A SER 302.A OG THR 301.A O no hydrogen 2.818 N/A ILE 304.A N PRO 292.A O no hydrogen 2.938 N/A LYS 309.A N GLU 312.A OE1 no hydrogen 3.225 N/A GLU 312.A N LYS 309.A O no hydrogen 2.895 N/A VAL 313.A N LYS 309.A O no hydrogen 3.189 N/A GLN 315.A N ASP 311.A O no hydrogen 3.242 N/A GLN 315.A NE2 ASP 311.A OD2 no hydrogen 3.113 N/A LEU 316.A N GLU 312.A O no hydrogen 2.871 N/A LYS 317.A N VAL 313.A O no hydrogen 2.912 N/A LYS 317.A NZ GLY 282.A O no hydrogen 2.666 N/A LYS 318.A NZ GLN 315.A O no hydrogen 2.984 N/A SER 319.A N GLN 315.A O no hydrogen 3.300 N/A SER 319.A N LEU 316.A O no hydrogen 3.062 N/A SER 319.A OG SER 196.A OG no hydrogen 2.754 N/A ALA 320.A N LEU 316.A O no hydrogen 3.063 N/A ASP 321.A N LYS 317.A O no hydrogen 3.028 N/A THR 322.A OG1 LYS 318.A O no hydrogen 2.890 N/A LEU 323.A N SER 319.A O no hydrogen 3.203 N/A LEU 323.A N ALA 320.A O no hydrogen 3.133 N/A TRP 324.A N ALA 320.A O no hydrogen 3.111 N/A ASP 325.A N ASP 321.A O no hydrogen 3.060 N/A GLN 327.A N LEU 323.A O no hydrogen 2.890 N/A LYS 328.A NZ ASP 329.A OD1 no hydrogen 3.441 N/A LYS 328.A NZ ASP 329.A OD2 no hydrogen 3.265 N/A LEU 330.A N GLN 327.A O no hydrogen 3.227 N/A