Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 1tdc_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLN 4.A N MET 1.A O no hydrogen 3.217 N/A TYR 6.A N GLU 3.A O no hydrogen 2.632 N/A TYR 6.A OH ILE 222.A O no hydrogen 3.174 N/A LEU 7.A N GLU 3.A O no hydrogen 3.443 N/A ASP 8.A N GLN 4.A O no hydrogen 3.114 N/A LEU 9.A N PRO 5.A O no hydrogen 3.328 N/A ALA 10.A N TYR 6.A O no hydrogen 3.272 N/A LYS 11.A N LEU 7.A O no hydrogen 3.360 N/A LYS 12.A N ASP 8.A O no hydrogen 2.702 N/A LYS 12.A NZ GLU 16.A OE2 no hydrogen 3.005 N/A LEU 14.A N ALA 10.A O no hydrogen 3.398 N/A ASP 15.A N LYS 12.A O no hydrogen 3.159 N/A GLU 16.A N LYS 12.A O no hydrogen 2.667 N/A HIS 18.A N SER 30.A O no hydrogen 3.416 N/A LYS 20.A N THR 28.A O no hydrogen 2.887 N/A LYS 20.A NZ ASP 257.A OD2 no hydrogen 2.897 N/A ARG 23.A NE THR 24.A OG1 no hydrogen 3.420 N/A ARG 23.A NE THR 26.A OG1 no hydrogen 3.270 N/A ARG 23.A NH2 THR 24.A OG1 no hydrogen 2.784 N/A THR 24.A N THR 26.A OG1 no hydrogen 3.205 N/A HIS 25.A N ASP 22.A O no hydrogen 2.747 N/A THR 26.A N THR 24.A O no hydrogen 2.613 N/A THR 26.A OG1 THR 24.A O no hydrogen 3.249 N/A THR 28.A OG1 ASP 22.A OD1 no hydrogen 3.191 N/A TYR 29.A N LEU 260.A O no hydrogen 3.012 N/A SER 30.A N HIS 18.A O no hydrogen 3.249 N/A SER 30.A OG ASP 257.A OD2 no hydrogen 2.760 N/A ILE 31.A N ALA 258.A O no hydrogen 3.017 N/A GLY 33.A N GLY 256.A O no hydrogen 2.947 N/A GLN 35.A NE2 THR 254.A OG1 no hydrogen 2.820 N/A MET 36.A N HIS 253.A O no hydrogen 3.001 N/A ARG 37.A NH1 GLU 250.A OE1 no hydrogen 3.019 N/A PHE 38.A N PHE 251.A O no hydrogen 2.697 N/A LEU 40.A N GLY 249.A O no hydrogen 2.849 N/A SER 41.A N ASP 39.A OD1 no hydrogen 3.033 N/A SER 41.A OG ASP 39.A OD1 no hydrogen 2.514 N/A LYS 42.A N ASP 39.A O no hydrogen 3.229 N/A PHE 44.A N PRO 280.A O no hydrogen 3.240 N/A LEU 46.A N PHE 44.A O no hydrogen 2.736 N/A THR 48.A N GLU 3.A OE1 no hydrogen 3.182 N/A THR 48.A N GLU 3.A OE2 no hydrogen 3.074 N/A THR 48.A OG1 GLU 3.A OE1 no hydrogen 2.830 N/A THR 48.A OG1 GLU 3.A OE2 no hydrogen 3.286 N/A THR 48.A OG1 ARG 277.A O no hydrogen 3.169 N/A THR 49.A OG1 GLU 3.A OE2 no hydrogen 2.894 N/A LYS 50.A NZ ILE 310.A O no hydrogen 3.550 N/A LYS 51.A NZ VAL 52.A O no hydrogen 2.942 N/A VAL 52.A N TYR 304.A OH no hydrogen 2.803 N/A LEU 56.A N PRO 53.A O no hydrogen 3.179 N/A ILE 57.A N PRO 53.A O no hydrogen 3.345 N/A ILE 57.A N PHE 54.A O no hydrogen 2.866 N/A LYS 58.A N PHE 54.A O no hydrogen 2.912 N/A LYS 58.A NZ MET 296.A O no hydrogen 2.905 N/A LYS 58.A NZ ILE 299.A O no hydrogen 3.274 N/A SER 59.A N GLY 55.A O no hydrogen 3.239 N/A SER 59.A OG GLY 55.A O no hydrogen 2.948 N/A LEU 61.A N ILE 57.A O no hydrogen 2.980 N/A LEU 62.A N LYS 58.A O no hydrogen 2.988 N/A TRP 63.A N GLU 60.A O no hydrogen 2.775 N/A TRP 63.A NE1 ASN 70.A O no hydrogen 3.165 N/A PHE 64.A N GLU 60.A O no hydrogen 2.899 N/A LEU 65.A N LEU 61.A O no hydrogen 2.822 N/A HIS 66.A N LEU 62.A O no hydrogen 3.332 N/A HIS 66.A N TRP 63.A O no hydrogen 2.840 N/A HIS 66.A NE2 PHE 294.A O no hydrogen 3.179 N/A GLY 67.A N TRP 63.A O no hydrogen 3.052 N/A GLY 67.A N PHE 64.A O no hydrogen 2.649 N/A ASP 68.A N TRP 63.A O no hydrogen 3.359 N/A THR 69.A N ASP 68.A OD1 no hydrogen 2.849 N/A THR 69.A OG1 ASP 141.A OD1 no hydrogen 2.573 N/A ASN 70.A ND2 ALA 136.A O no hydrogen 3.308 N/A ILE 71.A N GLY 140.A O no hydrogen 2.813 N/A ARG 72.A N ASN 70.A OD1 no hydrogen 2.796 N/A PHE 73.A N ASN 70.A O no hydrogen 2.675 N/A LEU 74.A N ILE 71.A O no hydrogen 2.976 N/A LEU 75.A N ILE 71.A O no hydrogen 2.857 N/A GLN 76.A N ARG 72.A O no hydrogen 3.013 N/A HIS 77.A N LEU 74.A O no hydrogen 2.526 N/A HIS 77.A ND1 PHE 73.A O no hydrogen 2.760 N/A ARG 78.A N LEU 75.A O no hydrogen 3.242 N/A HIS 80.A ND1 ASP 83.A OD2 no hydrogen 2.750 N/A ILE 81.A N ASN 79.A OD1 no hydrogen 3.280 N/A TRP 82.A NE1 GLU 60.A OE2 no hydrogen 3.002 N/A GLU 84.A N GLU 84.A OE1 no hydrogen 3.063 N/A TRP 85.A N TRP 82.A O no hydrogen 2.797 N/A PHE 87.A N ASP 83.A O no hydrogen 2.550 N/A GLU 88.A N GLU 84.A O no hydrogen 2.830 N/A LYS 89.A NZ TYR 139.A O no hydrogen 2.447 N/A TRP 90.A N ALA 86.A O no hydrogen 3.173 N/A VAL 91.A N GLU 88.A O no hydrogen 2.825 N/A LYS 92.A NZ LYS 89.A O no hydrogen 3.036 N/A LYS 92.A NZ SER 93.A O no hydrogen 3.132 N/A LYS 92.A NZ TYR 139.A OH no hydrogen 3.306 N/A TYR 96.A N SER 93.A O no hydrogen 3.462 N/A THR 102.A OG1 ASP 100.A O no hydrogen 2.612 N/A HIS 106.A N ASP 103.A O no hydrogen 3.118 N/A SER 108.A N PHE 104.A O no hydrogen 2.847 N/A SER 108.A OG PHE 104.A O no hydrogen 2.572 N/A GLN 109.A N HIS 106.A O no hydrogen 3.181 N/A VAL 117.A N GLU 113.A O no hydrogen 2.962 N/A TYR 118.A N PHE 114.A O no hydrogen 2.848 N/A HIS 119.A N ALA 115.A O no hydrogen 2.610 N/A GLU 120.A N VAL 117.A O no hydrogen 2.781 N/A GLU 121.A N VAL 117.A O no hydrogen 3.031 N/A MET 122.A N TYR 118.A O no hydrogen 3.074 N/A LYS 124.A N GLU 120.A O no hydrogen 2.911 N/A PHE 125.A N GLU 121.A O no hydrogen 2.863 N/A ASP 126.A N MET 122.A O no hydrogen 2.915 N/A ASP 127.A N ALA 123.A O no hydrogen 2.699 N/A ARG 128.A N LYS 124.A O no hydrogen 3.007 N/A ARG 128.A NH2 GLU 95.A OE1 no hydrogen 2.950 N/A ARG 128.A NH2 GLU 95.A OE2 no hydrogen 2.593 N/A VAL 129.A N PHE 125.A O no hydrogen 3.009 N/A LEU 130.A N ASP 126.A O no hydrogen 3.154 N/A HIS 131.A N ARG 128.A O no hydrogen 2.684 N/A ASP 132.A N ARG 128.A O no hydrogen 2.955 N/A PHE 135.A N ASP 132.A O no hydrogen 2.752 N/A ALA 136.A N ASP 132.A O no hydrogen 2.860 N/A ALA 137.A N ASP 133.A O no hydrogen 2.929 N/A LYS 138.A N ALA 134.A O no hydrogen 3.115 N/A TYR 139.A N PHE 135.A O no hydrogen 2.822 N/A TYR 139.A OH SER 93.A O no hydrogen 3.366 N/A GLY 140.A N ALA 136.A O no hydrogen 2.827 N/A LEU 142.A N THR 69.A O no hydrogen 3.105 N/A GLY 143.A N ASP 141.A OD1 no hydrogen 3.221 N/A LEU 144.A N LEU 142.A O no hydrogen 3.047 N/A VAL 145.A N SER 148.A OG no hydrogen 3.185 N/A SER 148.A N VAL 145.A O no hydrogen 3.023 N/A SER 148.A OG GLY 143.A O no hydrogen 2.865 N/A SER 148.A OG VAL 145.A O no hydrogen 3.134 N/A GLN 149.A N VAL 145.A O no hydrogen 2.944 N/A TRP 150.A N TYR 146.A O no hydrogen 2.667 N/A ARG 151.A N GLY 147.A O no hydrogen 3.122 N/A ARG 151.A NH1 LEU 65.A O no hydrogen 3.093 N/A ARG 151.A NH2 ASP 162.A OD2 no hydrogen 2.826 N/A TRP 153.A N ILE 161.A O no hydrogen 2.686 N/A THR 155.A N ASP 159.A O no hydrogen 2.940 N/A THR 155.A OG1 LYS 157.A O no hydrogen 2.841 N/A THR 155.A OG1 ASP 159.A O no hydrogen 2.779 N/A ASP 159.A N LYS 157.A O no hydrogen 2.833 N/A ILE 161.A N TRP 153.A O no hydrogen 2.911 N/A GLN 163.A NE2 GLN 149.A O no hydrogen 3.028 N/A GLN 163.A NE2 SER 183.A O no hydrogen 2.863 N/A LEU 164.A N TRP 150.A O no hydrogen 2.951 N/A GLY 165.A N ASP 162.A OD1 no hydrogen 2.860 N/A ASP 166.A N ASP 162.A O no hydrogen 3.308 N/A VAL 167.A N GLN 163.A O no hydrogen 3.228 N/A ILE 168.A N LEU 164.A O no hydrogen 2.970 N/A GLU 169.A N GLY 165.A O no hydrogen 3.411 N/A GLN 170.A N ASP 166.A O no hydrogen 2.917 N/A ILE 171.A N VAL 167.A O no hydrogen 2.728 N/A ILE 171.A N ILE 168.A O no hydrogen 2.662 N/A LYS 172.A N ILE 168.A O no hydrogen 3.049 N/A THR 173.A N GLU 169.A O no hydrogen 3.055 N/A THR 173.A OG1 GLU 169.A O no hydrogen 2.830 N/A HIS 174.A N GLN 170.A O no hydrogen 2.895 N/A ILE 181.A N ARG 179.A O no hydrogen 3.002 N/A VAL 182.A N TYR 202.A O no hydrogen 3.241 N/A SER 183.A N GLN 163.A OE1 no hydrogen 3.011 N/A ALA 184.A N THR 200.A O no hydrogen 2.874 N/A GLU 188.A N ASN 186.A OD1 no hydrogen 3.187 N/A CYS 198.A N TYR 146.A OH no hydrogen 3.185 N/A CYS 198.A SG SER 219.A O no hydrogen 3.635 N/A HIS 199.A NE2 ASN 229.A OD1 no hydrogen 3.042 N/A THR 200.A N TYR 216.A O no hydrogen 2.936 N/A THR 200.A OG1 CYS 198.A O no hydrogen 3.537 N/A GLN 203.A N GLN 214.A O no hydrogen 3.237 N/A PHE 204.A N LEU 180.A O no hydrogen 3.225 N/A TYR 205.A N SER 212.A O no hydrogen 3.050 N/A ASN 207.A N LYS 210.A O no hydrogen 2.859 N/A LYS 210.A N ASN 207.A O no hydrogen 2.629 N/A LYS 210.A NZ GLU 247.A OE1 no hydrogen 3.407 N/A LEU 211.A N GLU 247.A O no hydrogen 3.101 N/A SER 212.A N TYR 205.A O no hydrogen 3.346 N/A LEU 213.A N GLU 250.A O no hydrogen 3.015 N/A GLN 214.A N GLN 203.A O no hydrogen 2.964 N/A LEU 215.A N ILE 252.A O no hydrogen 2.914 N/A TYR 216.A N LEU 201.A O no hydrogen 2.889 N/A GLN 217.A N THR 254.A O no hydrogen 3.296 N/A GLN 217.A NE2 SER 219.A O no hydrogen 3.127 N/A GLN 217.A NE2 ASN 229.A OD1 no hydrogen 3.081 N/A ARG 218.A N CYS 198.A O no hydrogen 3.040 N/A ARG 218.A NH1 PRO 197.A O no hydrogen 3.443 N/A ALA 220.A N ASP 257.A O no hydrogen 3.427 N/A ILE 222.A N HIS 259.A O no hydrogen 2.746 N/A LEU 224.A N ASP 221.A OD1 no hydrogen 3.277 N/A GLY 225.A N ASP 221.A O no hydrogen 2.964 N/A ASN 229.A N GLY 225.A O no hydrogen 3.215 N/A ILE 230.A N VAL 226.A O no hydrogen 3.291 N/A SER 232.A N PHE 228.A O no hydrogen 3.223 N/A SER 232.A OG PHE 228.A O no hydrogen 2.844 N/A TYR 233.A N ASN 229.A O no hydrogen 3.342 N/A TYR 233.A OH HIS 199.A ND1 no hydrogen 2.721 N/A ALA 234.A N ILE 230.A O no hydrogen 3.071 N/A LEU 235.A N SER 232.A O no hydrogen 3.238 N/A LEU 236.A N SER 232.A O no hydrogen 3.241 N/A THR 237.A N TYR 233.A O no hydrogen 3.216 N/A THR 237.A OG1 TYR 233.A O no hydrogen 2.911 N/A HIS 238.A ND1 ALA 234.A O no hydrogen 3.134 N/A LEU 239.A N LEU 235.A O no hydrogen 3.094 N/A LEU 239.A N LEU 236.A O no hydrogen 3.219 N/A VAL 240.A N LEU 236.A O no hydrogen 2.850 N/A ALA 241.A N THR 237.A O no hydrogen 3.113 N/A HIS 242.A N HIS 238.A O no hydrogen 3.082 N/A HIS 242.A NE2 ASN 285.A O no hydrogen 2.985 N/A GLU 243.A N LEU 239.A O no hydrogen 3.097 N/A CYS 244.A N VAL 240.A O no hydrogen 2.792 N/A CYS 244.A SG VAL 240.A O no hydrogen 3.413 N/A LEU 246.A N ALA 241.A O no hydrogen 3.304 N/A GLU 247.A N GLY 209.A O no hydrogen 3.270 N/A GLY 249.A N LEU 211.A O no hydrogen 2.778 N/A GLU 250.A N SER 212.A OG no hydrogen 2.889 N/A PHE 251.A N PHE 38.A O no hydrogen 3.018 N/A ILE 252.A N LEU 213.A O no hydrogen 3.150 N/A HIS 253.A N MET 36.A O no hydrogen 2.834 N/A HIS 253.A NE2 GLN 217.A OE1 no hydrogen 2.846 N/A THR 254.A N LEU 215.A O no hydrogen 3.127 N/A THR 254.A OG1 GLN 214.A OE1 no hydrogen 3.010 N/A PHE 255.A N HIS 34.A O no hydrogen 2.815 N/A GLY 256.A N GLN 217.A O no hydrogen 3.001 N/A ASP 257.A N ARG 218.A O no hydrogen 3.229 N/A ALA 258.A N ILE 31.A O no hydrogen 3.222 N/A HIS 259.A N ALA 220.A O no hydrogen 2.968 N/A HIS 259.A ND1 ASP 257.A OD1 no hydrogen 2.966 N/A LEU 260.A N TYR 29.A O no hydrogen 2.767 N/A VAL 262.A N GLY 27.A O no hydrogen 2.818 N/A ASN 263.A ND2 VAL 314.A O no hydrogen 2.975 N/A ASN 263.A ND2 ALA 315.A O no hydrogen 2.808 N/A HIS 264.A N TYR 261.A O no hydrogen 3.388 N/A HIS 264.A NE2 PRO 313.A O no hydrogen 2.583 N/A LEU 265.A N VAL 262.A O no hydrogen 3.074 N/A ILE 268.A N HIS 264.A O no hydrogen 3.141 N/A LYS 269.A N LEU 265.A O no hydrogen 3.463 N/A GLU 270.A N ASP 266.A O no hydrogen 3.147 N/A GLN 271.A N GLN 267.A O no hydrogen 3.142 N/A LEU 272.A N ILE 268.A O no hydrogen 3.030 N/A SER 273.A N GLU 270.A O no hydrogen 2.958 N/A SER 273.A OG GLU 270.A O no hydrogen 2.821 N/A ARG 274.A N GLN 271.A O no hydrogen 2.690 N/A ARG 274.A NH1 THR 49.A O no hydrogen 2.723 N/A ARG 274.A NH1 PRO 308.A O no hydrogen 2.897 N/A ARG 274.A NH2 PRO 308.A O no hydrogen 3.356 N/A ARG 277.A N THR 48.A OG1 no hydrogen 2.777 N/A ARG 277.A NE ASP 305.A O no hydrogen 3.166 N/A ARG 277.A NH1 TYR 307.A OH no hydrogen 3.074 N/A THR 281.A N LEU 302.A O no hydrogen 2.870 N/A THR 281.A OG1 LEU 302.A O no hydrogen 3.483 N/A THR 281.A OG1 ASN 303.A OD1 no hydrogen 3.418 N/A GLN 283.A N GLN 283.A OE1 no hydrogen 3.036 N/A GLN 283.A N LYS 300.A O no hydrogen 2.869 N/A ASN 285.A N ASP 298.A O no hydrogen 2.831 N/A ASP 287.A N ASN 285.A OD1 no hydrogen 3.154 N/A ASP 293.A N ASP 290.A O no hydrogen 3.040 N/A ASP 295.A N ASP 298.A OD2 no hydrogen 2.872 N/A ASP 298.A N ASP 295.A O no hydrogen 2.830 N/A ILE 299.A N MET 296.A O no hydrogen 2.999 N/A LYS 300.A N GLN 283.A O no hydrogen 2.924 N/A LYS 300.A NZ LYS 297.A O no hydrogen 2.650 N/A LEU 302.A N THR 281.A O no hydrogen 3.230 N/A TYR 304.A OH LEU 47.A O no hydrogen 2.948 N/A TYR 307.A N THR 48.A O no hydrogen 3.054 N/A