Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 1tme_2.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 2.A NE THR 18.A O no hydrogen 2.993 N/A ARG 2.A NH1 THR 187.A O no hydrogen 3.344 N/A ARG 2.A NH2 SER 17.A O no hydrogen 2.604 N/A ARG 2.A NH2 THR 187.A O no hydrogen 2.536 N/A ALA 4.A N THR 15.A O no hydrogen 2.634 N/A SER 5.A OG THR 13.A O no hydrogen 3.393 N/A SER 5.A OG ASN 14.A OD1 no hydrogen 2.634 N/A ASP 6.A N THR 13.A O no hydrogen 2.979 N/A ALA 8.A N SER 11.A O no hydrogen 2.672 N/A SER 11.A N ALA 8.A O no hydrogen 2.889 N/A SER 11.A OG ALA 8.A O no hydrogen 2.668 N/A THR 13.A N ASP 6.A O no hydrogen 2.817 N/A THR 13.A OG1 ASP 6.A O no hydrogen 3.537 N/A THR 15.A N ALA 4.A O no hydrogen 2.717 N/A THR 15.A OG1 THR 190.A OG1 no hydrogen 2.955 N/A SER 17.A N THR 15.A OG1 no hydrogen 3.233 N/A SER 17.A OG THR 189.A OG1 no hydrogen 3.140 N/A THR 18.A N ARG 2.A O no hydrogen 2.833 N/A GLY 20.A N THR 18.A OG1 no hydrogen 2.819 N/A ARG 21.A NH2 TYR 51.A OH no hydrogen 3.359 N/A LEU 22.A N ASP 192.A O no hydrogen 2.845 N/A CYS 23.A SG GLY 24.A O no hydrogen 4.024 N/A GLY 24.A N GLU 194.A O no hydrogen 2.708 N/A GLU 27.A N GLY 24.A O no hydrogen 3.102 N/A HIS 29.A ND1 VAL 241.A O no hydrogen 2.828 N/A GLU 32.A N GLU 32.A OE1 no hydrogen 2.525 N/A HIS 33.A NE2 ASP 43.A OD2 no hydrogen 2.786 N/A CYS 37.A N PRO 34.A O no hydrogen 3.022 N/A THR 42.A N PHE 245.A O no hydrogen 2.794 N/A ALA 48.A N VAL 45.A O no hydrogen 2.654 N/A GLU 49.A N VAL 45.A O no hydrogen 3.034 N/A GLU 49.A N LEU 46.A O no hydrogen 2.837 N/A ARG 50.A NE ASN 10.A OD1 no hydrogen 2.888 N/A ARG 50.A NH2 ASN 10.A OD1 no hydrogen 2.978 N/A TYR 51.A N SER 11.A OG no hydrogen 3.050 N/A TYR 51.A OH ASP 6.A OD2 no hydrogen 2.268 N/A TYR 52.A N ILE 238.A O no hydrogen 2.720 N/A THR 53.A OG1 SER 237.A OG no hydrogen 2.596 N/A ILE 54.A N ALA 236.A O no hydrogen 2.851 N/A LEU 56.A N ILE 234.A O no hydrogen 2.956 N/A ALA 57.A N ILE 234.A O no hydrogen 2.843 N/A SER 58.A OG GLN 233.A OE1 no hydrogen 3.378 N/A TRP 59.A N VAL 232.A O no hydrogen 2.886 N/A THR 60.A N GLN 63.A OE1 no hydrogen 2.789 N/A THR 60.A OG1 GLN 63.A OE1 no hydrogen 2.835 N/A THR 62.A N THR 60.A OG1 no hydrogen 3.121 N/A GLN 63.A N THR 60.A O no hydrogen 3.181 N/A PHE 66.A N VAL 218.A O no hydrogen 2.480 N/A SER 67.A N GLU 64.A O no hydrogen 2.812 N/A SER 67.A OG GLU 64.A O no hydrogen 2.472 N/A HIS 68.A N ARG 147.A O no hydrogen 2.828 N/A ILE 69.A N VAL 216.A O no hydrogen 2.848 N/A ARG 70.A N ASP 143.A OD2 no hydrogen 2.598 N/A ARG 70.A NE ASP 143.A OD1 no hydrogen 3.396 N/A ARG 70.A NE ASP 143.A OD2 no hydrogen 2.613 N/A ARG 70.A NH1 TYR 124.A O no hydrogen 3.188 N/A ARG 70.A NH1 GLY 126.A O no hydrogen 2.761 N/A ARG 70.A NH2 GLY 126.A O no hydrogen 2.852 N/A ARG 70.A NH2 ASP 143.A OD1 no hydrogen 2.908 N/A ILE 71.A N LEU 214.A O no hydrogen 2.732 N/A LEU 73.A N TRP 212.A O no hydrogen 2.947 N/A HIS 75.A NE2 HIS 209.A O no hydrogen 3.214 N/A VAL 76.A N PRO 72.A O no hydrogen 2.934 N/A LEU 77.A N PRO 74.A O no hydrogen 2.634 N/A ALA 78.A N HIS 75.A O no hydrogen 2.747 N/A GLY 82.A N GLY 79.A O no hydrogen 2.969 N/A GLY 83.A N GLU 80.A O no hydrogen 3.023 N/A PHE 85.A N TYR 52.A OH no hydrogen 3.226 N/A GLY 86.A N GLY 82.A O no hydrogen 2.802 N/A ALA 87.A N GLY 83.A O no hydrogen 2.870 N/A THR 88.A N VAL 84.A O no hydrogen 2.846 N/A THR 88.A OG1 VAL 84.A O no hydrogen 2.748 N/A LEU 89.A N PHE 85.A O no hydrogen 2.803 N/A ARG 90.A N GLY 86.A O no hydrogen 2.806 N/A ARG 90.A NE GLU 251.A OE2 no hydrogen 2.792 N/A ARG 90.A NH1 ALA 78.A O no hydrogen 2.628 N/A ARG 91.A N THR 88.A O no hydrogen 3.083 N/A HIS 92.A N LEU 89.A O no hydrogen 3.163 N/A HIS 92.A ND1 THR 88.A O no hydrogen 2.887 N/A TYR 93.A N GLY 247.A O no hydrogen 2.789 N/A LEU 94.A N ASN 246.A O no hydrogen 2.971 N/A CYS 95.A N SER 204.A O no hydrogen 2.955 N/A CYS 95.A SG VAL 244.A O no hydrogen 4.046 N/A LYS 96.A N VAL 244.A O no hydrogen 2.992 N/A LYS 96.A NZ HIS 29.A NE2 no hydrogen 2.820 N/A LYS 96.A NZ GLU 32.A O no hydrogen 2.564 N/A LYS 96.A NZ GLU 32.A OE1 no hydrogen 3.458 N/A THR 97.A OG1 GLY 98.A O no hydrogen 2.937 N/A THR 97.A OG1 VAL 241.A O no hydrogen 3.281 N/A GLY 98.A N VAL 241.A O no hydrogen 3.158 N/A TRP 99.A N VAL 195.A O no hydrogen 2.989 N/A ARG 100.A N GLN 239.A O no hydrogen 2.766 N/A ARG 100.A NH1 ASP 6.A OD2 no hydrogen 3.207 N/A VAL 101.A N LEU 193.A O no hydrogen 2.766 N/A GLN 102.A N SER 237.A O no hydrogen 2.860 N/A GLN 102.A NE2 ASP 192.A OD1 no hydrogen 3.459 N/A GLN 102.A NE2 ASP 192.A OD2 no hydrogen 2.751 N/A VAL 103.A N VAL 191.A O no hydrogen 3.027 N/A GLN 104.A N THR 235.A O no hydrogen 2.725 N/A GLN 104.A NE2 GLN 102.A OE1 no hydrogen 3.099 N/A GLN 104.A NE2 SER 237.A OG no hydrogen 2.905 N/A CYS 105.A N THR 189.A O no hydrogen 2.801 N/A CYS 105.A SG GLN 233.A O no hydrogen 3.543 N/A SER 108.A OG HIS 111.A ND1 no hydrogen 2.634 N/A PHE 110.A N SER 108.A OG no hydrogen 2.965 N/A HIS 111.A N SER 108.A O no hydrogen 2.960 N/A HIS 111.A ND1 SER 108.A OG no hydrogen 2.634 N/A HIS 111.A NE2 SER 229.A O no hydrogen 2.861 N/A ALA 112.A N GLN 223.A O no hydrogen 2.764 N/A SER 114.A N SER 220.A O no hydrogen 2.936 N/A SER 114.A OG SER 220.A OG no hydrogen 2.634 N/A LEU 115.A N LEU 183.A O no hydrogen 2.822 N/A LEU 116.A N ALA 217.A O no hydrogen 2.481 N/A VAL 117.A N GLN 181.A O no hydrogen 3.068 N/A PHE 118.A N VAL 215.A O no hydrogen 2.796 N/A MET 119.A N PRO 179.A O no hydrogen 2.992 N/A ALA 120.A N THR 213.A O no hydrogen 3.034 N/A GLU 122.A N ASN 211.A O no hydrogen 2.791 N/A TYR 124.A OH TYR 158.A OH no hydrogen 2.756 N/A THR 125.A OG1 PRO 139.A O no hydrogen 2.491 N/A LYS 127.A N THR 137.A O no hydrogen 2.855 N/A LYS 127.A NZ THR 125.A O no hydrogen 2.899 N/A LYS 127.A NZ ASP 138.A O no hydrogen 2.409 N/A LYS 127.A NZ THR 141.A O no hydrogen 2.464 N/A LYS 130.A N GLU 135.A O no hydrogen 2.673 N/A THR 131.A OG1 THR 131.A O no hydrogen 2.459 N/A THR 137.A OG1 GLY 128.A O no hydrogen 3.023 N/A THR 141.A N ASP 138.A O no hydrogen 3.175 N/A ASP 143.A N ARG 70.A O no hydrogen 3.019 N/A TRP 146.A NE1 SER 58.A O no hydrogen 2.981 N/A ARG 147.A N HIS 68.A O no hydrogen 2.676 N/A ARG 147.A NH1 LYS 127.A O no hydrogen 3.000 N/A ARG 147.A NH2 TYR 156.A OH no hydrogen 3.556 N/A THR 154.A N ALA 152.A O no hydrogen 2.461 N/A THR 154.A OG1 ALA 152.A O no hydrogen 3.394 N/A TYR 156.A N ASN 168.A OD1 no hydrogen 2.716 N/A ARG 157.A NE GLY 163.A O no hydrogen 3.369 N/A ARG 157.A NH1 ASP 159.A OD2 no hydrogen 2.625 N/A ARG 157.A NH2 GLY 163.A O no hydrogen 3.140 N/A TYR 158.A OH TYR 124.A OH no hydrogen 2.756 N/A ARG 161.A N ASP 159.A OD1 no hydrogen 2.994 N/A ALA 166.A N THR 154.A O no hydrogen 2.947 N/A ASN 168.A ND2 TYR 156.A O no hydrogen 2.905 N/A HIS 169.A N ALA 166.A O no hydrogen 2.924 N/A GLN 172.A NE2 GLN 170.A O no hydrogen 3.255 N/A TRP 173.A N ASN 171.A OD1 no hydrogen 3.175 N/A GLN 174.A N ASN 171.A O no hydrogen 2.934 N/A TRP 175.A N GLN 172.A O no hydrogen 2.879 N/A VAL 177.A N GLN 174.A O no hydrogen 2.936 N/A TYR 178.A N TRP 175.A O no hydrogen 3.160 N/A TYR 178.A OH GLN 170.A OE1 no hydrogen 2.720 N/A HIS 180.A ND1 TYR 178.A O no hydrogen 2.800 N/A GLN 181.A N VAL 117.A O no hydrogen 3.031 N/A GLN 181.A NE2 GLY 20.A O no hydrogen 2.692 N/A LEU 183.A N LEU 115.A O no hydrogen 2.796 N/A ASN 184.A N ASN 188.A OD1 no hydrogen 3.147 N/A ASN 184.A ND2 GLY 113.A O no hydrogen 3.125 N/A LEU 185.A N GLY 113.A O no hydrogen 3.218 N/A THR 187.A N ASN 184.A O no hydrogen 2.590 N/A ASN 188.A N ASN 184.A O no hydrogen 3.081 N/A ASN 188.A ND2 ILE 182.A O no hydrogen 3.261 N/A ASN 188.A ND2 THR 190.A O no hydrogen 3.144 N/A THR 189.A N SER 17.A OG no hydrogen 2.742 N/A THR 189.A OG1 SER 17.A OG no hydrogen 3.140 N/A THR 190.A OG1 THR 15.A OG1 no hydrogen 2.955 N/A VAL 191.A N VAL 103.A O no hydrogen 3.045 N/A ASP 192.A N GLN 181.A OE1 no hydrogen 2.945 N/A LEU 193.A N VAL 101.A O no hydrogen 2.792 N/A GLU 194.A N LEU 22.A O no hydrogen 2.940 N/A VAL 195.A N TRP 99.A O no hydrogen 2.768 N/A TYR 197.A OH ALA 201.A O no hydrogen 2.587 N/A ASN 199.A ND2 TYR 197.A OH no hydrogen 2.991 N/A ILE 200.A N ASN 199.A OD1 no hydrogen 2.650 N/A SER 204.A N CYS 95.A O no hydrogen 3.215 N/A TRP 206.A NE1 HIS 92.A O no hydrogen 2.910 N/A GLN 208.A N SER 205.A O no hydrogen 2.904 N/A HIS 209.A N TRP 206.A O no hydrogen 2.991 N/A HIS 209.A NE2 GLU 122.A OE1 no hydrogen 2.854 N/A ASN 211.A ND2 VAL 198.A O no hydrogen 2.959 N/A TRP 212.A NE1 PRO 196.A O no hydrogen 3.098 N/A THR 213.A N ALA 120.A O no hydrogen 2.945 N/A THR 213.A OG1 PHE 123.A O no hydrogen 3.371 N/A LEU 214.A N ILE 71.A O no hydrogen 2.723 N/A VAL 215.A N PHE 118.A O no hydrogen 2.730 N/A VAL 216.A N ILE 69.A O no hydrogen 3.059 N/A ALA 217.A N LEU 116.A O no hydrogen 2.785 N/A VAL 218.A N SER 67.A O no hydrogen 2.812 N/A PHE 219.A N SER 114.A O no hydrogen 2.844 N/A SER 220.A N SER 114.A O no hydrogen 3.310 N/A SER 220.A N SER 114.A OG no hydrogen 3.124 N/A SER 220.A OG SER 114.A OG no hydrogen 2.634 N/A GLN 223.A N ALA 112.A O no hydrogen 2.654 N/A SER 228.A N ALA 225.A O no hydrogen 3.003 N/A GLN 233.A NE2 SER 58.A OG no hydrogen 3.179 N/A ILE 234.A N ALA 57.A O no hydrogen 2.637 N/A THR 235.A N GLN 104.A O no hydrogen 2.918 N/A THR 235.A OG1 GLN 104.A OE1 no hydrogen 2.645 N/A ALA 236.A N ILE 54.A O no hydrogen 2.905 N/A SER 237.A N GLN 102.A O no hydrogen 2.682 N/A SER 237.A OG THR 53.A OG1 no hydrogen 2.596 N/A ILE 238.A N TYR 52.A O no hydrogen 2.918 N/A GLN 239.A N ARG 100.A O no hydrogen 2.842 N/A VAL 241.A N GLY 98.A O no hydrogen 2.707 N/A ASN 242.A ND2 HIS 29.A O no hydrogen 2.372 N/A VAL 244.A N LYS 96.A O no hydrogen 2.841 N/A PHE 245.A N THR 42.A O no hydrogen 2.833 N/A ASN 246.A N LEU 94.A O no hydrogen 2.908 N/A ASN 246.A ND2 ASP 39.A OD1 no hydrogen 3.136 N/A GLY 247.A N ASP 39.A OD2 no hydrogen 2.963 N/A ARG 249.A N ARG 91.A O no hydrogen 2.815 N/A ARG 249.A NH1 ARG 90.A O no hydrogen 3.127 N/A ARG 249.A NH1 HIS 250.A O no hydrogen 2.962 N/A THR 252.A N ARG 90.A O no hydrogen 2.674 N/A ILE 254.A N THR 252.A O no hydrogen 2.801 N/A