Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 1tth_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASN 2.A N ARG 306.A O no hydrogen 2.614 N/A ASN 2.A ND2 LEU 302.A O no hydrogen 2.841 N/A ASN 2.A ND2 ASN 305.A O no hydrogen 2.603 N/A ASN 2.A ND2 ARG 306.A O no hydrogen 3.427 N/A TYR 5.A N ASN 2.A O no hydrogen 3.143 N/A GLN 6.A N VAL 303.A O no hydrogen 3.052 N/A LYS 7.A N LEU 4.A O no hydrogen 3.358 N/A ILE 12.A N GLN 133.A OE1 no hydrogen 2.671 N/A ASN 13.A N SER 11.A OG no hydrogen 3.026 N/A ASP 14.A N SER 11.A O no hydrogen 3.137 N/A LEU 15.A N ILE 12.A O no hydrogen 3.167 N/A SER 16.A N ASP 19.A OD2 no hydrogen 3.124 N/A ASP 19.A N SER 16.A OG no hydrogen 3.156 N/A LEU 20.A N SER 16.A O no hydrogen 2.754 N/A ASN 21.A N ARG 17.A O no hydrogen 2.540 N/A LEU 22.A N ASP 18.A O no hydrogen 2.667 N/A VAL 23.A N ASP 19.A O no hydrogen 3.038 N/A LEU 24.A N LEU 20.A O no hydrogen 3.064 N/A ALA 25.A N ASN 21.A O no hydrogen 3.054 N/A THR 26.A N LEU 22.A O no hydrogen 3.013 N/A THR 26.A OG1 LEU 22.A O no hydrogen 2.918 N/A ALA 27.A N VAL 23.A O no hydrogen 2.612 N/A ALA 28.A N LEU 24.A O no hydrogen 2.787 N/A LYS 29.A N ALA 25.A O no hydrogen 2.879 N/A LYS 29.A NZ VAL 309.A O no hydrogen 2.898 N/A LEU 30.A N THR 26.A O no hydrogen 3.043 N/A LYS 31.A N ALA 27.A O no hydrogen 2.872 N/A ALA 32.A N LYS 29.A O no hydrogen 3.013 N/A ASN 33.A N LYS 29.A O no hydrogen 3.083 N/A GLN 35.A NE2 ASN 33.A O no hydrogen 2.815 N/A LEU 38.A N GLN 35.A O no hydrogen 2.838 N/A LEU 39.A N LEU 66.A O no hydrogen 2.724 N/A LYS 40.A N GLU 37.A O no hydrogen 3.215 N/A LYS 40.A NZ GLU 37.A OE1 no hydrogen 3.023 N/A LYS 42.A N LEU 39.A O no hydrogen 3.208 N/A VAL 43.A N ASP 100.A OD2 no hydrogen 3.109 N/A ILE 44.A N SER 69.A O no hydrogen 3.077 N/A ALA 45.A N ALA 101.A O no hydrogen 2.970 N/A SER 46.A N VAL 71.A O no hydrogen 2.671 N/A SER 46.A OG GLU 60.A OE2 no hydrogen 2.677 N/A CYS 47.A N VAL 103.A O no hydrogen 2.725 N/A PHE 48.A N PHE 73.A O no hydrogen 2.615 N/A PHE 49.A N ARG 105.A O no hydrogen 2.852 N/A ARG 56.A N SER 52.A OG no hydrogen 2.607 N/A ARG 56.A NH1 GLU 60.A OE2 no hydrogen 2.600 N/A LEU 57.A N THR 53.A O no hydrogen 3.041 N/A SER 58.A N ARG 54.A O no hydrogen 2.808 N/A SER 58.A OG ARG 54.A O no hydrogen 3.042 N/A SER 58.A OG THR 55.A O no hydrogen 3.321 N/A PHE 59.A N THR 55.A O no hydrogen 3.218 N/A GLU 60.A N ARG 56.A O no hydrogen 3.136 N/A THR 61.A N LEU 57.A O no hydrogen 3.018 N/A THR 61.A OG1 LEU 57.A O no hydrogen 2.737 N/A SER 62.A N SER 58.A O no hydrogen 3.152 N/A SER 62.A OG SER 58.A O no hydrogen 3.143 N/A SER 62.A OG ILE 293.A O no hydrogen 3.051 N/A MET 63.A N PHE 59.A O no hydrogen 3.057 N/A HIS 64.A N GLU 60.A O no hydrogen 3.037 N/A ARG 65.A N THR 61.A O no hydrogen 2.633 N/A LEU 66.A N MET 63.A O no hydrogen 3.416 N/A GLY 67.A N HIS 64.A O no hydrogen 3.115 N/A SER 69.A N LYS 42.A O no hydrogen 3.125 N/A VAL 71.A N ILE 44.A O no hydrogen 3.003 N/A PHE 73.A N SER 46.A O no hydrogen 2.498 N/A ALA 77.A N ASP 75.A OD1 no hydrogen 3.292 N/A THR 79.A N SER 76.A O no hydrogen 2.961 N/A THR 79.A OG1 SER 76.A O no hydrogen 2.298 N/A GLY 82.A N THR 79.A OG1 no hydrogen 2.982 N/A LYS 83.A N THR 79.A O no hydrogen 2.952 N/A LYS 84.A N SER 80.A O no hydrogen 2.554 N/A GLU 86.A N SER 80.A O no hydrogen 3.477 N/A ASP 90.A N THR 87.A OG1 no hydrogen 3.232 N/A THR 91.A N THR 87.A O no hydrogen 2.850 N/A THR 91.A OG1 THR 87.A O no hydrogen 3.204 N/A ILE 92.A N LEU 88.A O no hydrogen 2.679 N/A SER 93.A N ALA 89.A O no hydrogen 2.579 N/A SER 93.A OG ALA 89.A O no hydrogen 3.212 N/A VAL 94.A N ASP 90.A O no hydrogen 2.868 N/A ILE 95.A N THR 91.A O no hydrogen 2.984 N/A SER 96.A N ILE 92.A O no hydrogen 2.932 N/A SER 96.A OG ILE 92.A O no hydrogen 2.564 N/A SER 96.A OG SER 93.A O no hydrogen 2.638 N/A SER 96.A OG PHE 118.A O no hydrogen 3.419 N/A THR 97.A N VAL 94.A O no hydrogen 2.915 N/A THR 97.A OG1 VAL 94.A O no hydrogen 2.624 N/A TYR 98.A N ILE 95.A O no hydrogen 2.879 N/A ASP 100.A N VAL 43.A O no hydrogen 2.854 N/A ILE 102.A N PRO 123.A O no hydrogen 3.113 N/A VAL 103.A N ALA 45.A O no hydrogen 2.822 N/A MET 104.A N LEU 125.A O no hydrogen 2.852 N/A ARG 105.A N CYS 47.A O no hydrogen 3.121 N/A ARG 105.A NE ALA 127.A O no hydrogen 3.170 N/A ARG 105.A NH1 ALA 51.A O no hydrogen 2.555 N/A ARG 105.A NH2 ALA 127.A O no hydrogen 3.394 N/A HIS 106.A N GLY 128.A O no hydrogen 2.940 N/A GLN 108.A N HIS 106.A ND1 no hydrogen 2.904 N/A GLY 110.A N ASP 129.A OD2 no hydrogen 2.524 N/A ARG 113.A NH1 ASP 14.A OD2 no hydrogen 3.105 N/A LEU 114.A N GLY 110.A O no hydrogen 3.048 N/A ALA 115.A N ALA 111.A O no hydrogen 3.153 N/A THR 116.A N ALA 112.A O no hydrogen 3.052 N/A THR 116.A N ARG 113.A O no hydrogen 2.706 N/A THR 116.A OG1 ARG 113.A O no hydrogen 2.639 N/A GLU 117.A N LEU 114.A O no hydrogen 3.000 N/A PHE 118.A N ALA 115.A O no hydrogen 2.866 N/A SER 119.A N ALA 115.A O no hydrogen 2.620 N/A SER 119.A OG GLY 120.A O no hydrogen 3.238 N/A SER 119.A OG VAL 122.A O no hydrogen 2.501 N/A VAL 124.A N HIS 8.A ND1 no hydrogen 2.698 N/A LEU 125.A N ILE 102.A O no hydrogen 2.653 N/A ASN 126.A N ILE 9.A O no hydrogen 3.234 N/A ASN 126.A ND2 ILE 10.A O no hydrogen 3.390 N/A ASN 126.A ND2 ASP 129.A OD1 no hydrogen 2.938 N/A ASN 126.A ND2 GLN 133.A O no hydrogen 3.679 N/A ALA 127.A N MET 104.A O no hydrogen 2.764 N/A GLY 128.A N ASN 126.A OD1 no hydrogen 2.659 N/A ASP 129.A N GLN 133.A O no hydrogen 3.164 N/A GLY 130.A N HIS 106.A O no hydrogen 3.147 N/A SER 131.A N GLU 109.A OE2 no hydrogen 3.219 N/A SER 131.A OG GLU 109.A OE2 no hydrogen 2.783 N/A ASN 132.A N ASP 129.A O no hydrogen 2.863 N/A ASN 132.A ND2 ASP 129.A OD2 no hydrogen 3.538 N/A GLN 133.A N ASP 129.A OD1 no hydrogen 2.944 N/A HIS 134.A N SER 171.A OG no hydrogen 3.018 N/A GLN 137.A NE2 ASP 141.A OD1 no hydrogen 3.276 N/A THR 138.A N HIS 134.A O no hydrogen 3.110 N/A LEU 139.A N PRO 135.A O no hydrogen 2.868 N/A LEU 140.A N THR 136.A O no hydrogen 3.357 N/A ASP 141.A N GLN 137.A O no hydrogen 2.960 N/A LEU 142.A N THR 138.A O no hydrogen 2.795 N/A PHE 143.A N LEU 139.A O no hydrogen 2.953 N/A THR 144.A N LEU 140.A O no hydrogen 2.901 N/A THR 144.A OG1 LEU 140.A O no hydrogen 2.564 N/A THR 144.A OG1 ASN 291.A OD1 no hydrogen 2.872 N/A ILE 145.A N ASP 141.A O no hydrogen 2.700 N/A GLN 146.A N LEU 142.A O no hydrogen 2.822 N/A GLU 147.A N PHE 143.A O no hydrogen 2.891 N/A THR 148.A N THR 144.A O no hydrogen 3.103 N/A THR 148.A OG1 THR 144.A O no hydrogen 2.829 N/A THR 148.A OG1 ILE 145.A O no hydrogen 3.230 N/A GLN 149.A NE2 THR 148.A OG1 no hydrogen 3.315 N/A GLN 149.A NE2 ASN 260.A O no hydrogen 3.133 N/A GLY 150.A N GLN 146.A O no hydrogen 2.839 N/A ARG 151.A NE ASP 153.A O no hydrogen 2.781 N/A ARG 151.A NE ASN 154.A O no hydrogen 3.376 N/A ARG 151.A NH2 ASN 154.A O no hydrogen 3.092 N/A ASN 154.A N ASP 180.A O no hydrogen 2.698 N/A LEU 155.A N ASN 182.A OD1 no hydrogen 2.935 N/A HIS 156.A N ASP 223.A OD1 no hydrogen 2.495 N/A HIS 156.A ND1 TYR 185.A OH no hydrogen 2.977 N/A VAL 157.A N ARG 183.A O no hydrogen 2.853 N/A ALA 158.A N ILE 224.A O no hydrogen 2.848 N/A MET 159.A N TYR 185.A O no hydrogen 3.017 N/A VAL 160.A N TYR 226.A O no hydrogen 3.006 N/A GLY 161.A N ILE 187.A O no hydrogen 3.190 N/A LEU 163.A N LEU 192.A O no hydrogen 3.008 N/A LYS 164.A N LEU 192.A O no hydrogen 3.044 N/A LYS 164.A NZ GLU 239.A OE2 no hydrogen 3.186 N/A TYR 165.A N ASP 162.A OD1 no hydrogen 3.026 N/A TYR 165.A OH GLU 239.A OE1 no hydrogen 2.829 N/A TYR 165.A OH GLU 239.A OE2 no hydrogen 3.145 N/A ARG 167.A NH1 GLY 130.A O no hydrogen 2.944 N/A HIS 170.A N GLY 166.A O no hydrogen 2.911 N/A HIS 170.A NE2 LEU 163.A O no hydrogen 2.582 N/A SER 171.A N ARG 167.A O no hydrogen 3.103 N/A SER 171.A OG GLN 133.A OE1 no hydrogen 2.967 N/A SER 171.A OG ARG 167.A O no hydrogen 3.522 N/A LEU 172.A N THR 168.A O no hydrogen 3.344 N/A THR 173.A N VAL 169.A O no hydrogen 3.029 N/A THR 173.A OG1 VAL 169.A O no hydrogen 3.313 N/A GLN 174.A N HIS 170.A O no hydrogen 3.442 N/A ALA 175.A N SER 171.A O no hydrogen 2.866 N/A LEU 176.A N LEU 172.A O no hydrogen 3.053 N/A ALA 177.A N THR 173.A O no hydrogen 3.110 N/A LYS 178.A N ALA 175.A O no hydrogen 3.125 N/A LYS 178.A NZ LEU 15.A O no hydrogen 3.026 N/A PHE 179.A N LEU 176.A O no hydrogen 2.726 N/A ASN 182.A ND2 LEU 152.A O no hydrogen 2.996 N/A ASN 182.A ND2 LEU 176.A O no hydrogen 2.727 N/A ARG 183.A N LEU 155.A O no hydrogen 2.822 N/A PHE 184.A N ALA 208.A O no hydrogen 3.013 N/A TYR 185.A N VAL 157.A O no hydrogen 2.872 N/A TYR 185.A OH HIS 156.A ND1 no hydrogen 2.977 N/A PHE 186.A N SER 210.A O no hydrogen 3.161 N/A ILE 187.A N MET 159.A O no hydrogen 3.104 N/A ILE 198.A N PRO 195.A O no hydrogen 3.191 N/A ASP 200.A N GLN 196.A O no hydrogen 2.998 N/A ASP 203.A N LEU 199.A O no hydrogen 2.684 N/A GLU 204.A N ASP 200.A O no hydrogen 2.770 N/A LYS 205.A N MET 201.A O no hydrogen 3.008 N/A LYS 205.A NZ ALA 177.A O no hydrogen 2.761 N/A GLY 206.A N ASP 203.A O no hydrogen 2.589 N/A TRP 209.A NE1 ASP 203.A OD1 no hydrogen 2.857 N/A SER 210.A N PHE 184.A O no hydrogen 2.908 N/A HIS 212.A N PHE 186.A O no hydrogen 2.956 N/A MET 219.A N ILE 215.A O no hydrogen 3.174 N/A GLU 221.A N VAL 218.A O no hydrogen 3.052 N/A ASP 223.A N HIS 156.A O no hydrogen 2.699 N/A ILE 224.A N HIS 156.A O no hydrogen 2.902 N/A LEU 225.A N LYS 262.A O no hydrogen 3.090 N/A TYR 226.A N ALA 158.A O no hydrogen 2.728 N/A TYR 226.A OH ASP 141.A OD1 no hydrogen 3.124 N/A TYR 226.A OH ASP 141.A OD2 no hydrogen 2.844 N/A MET 227.A N LEU 264.A O no hydrogen 2.706 N/A THR 228.A OG1 VAL 160.A O no hydrogen 2.772 N/A THR 228.A OG1 ASP 162.A O no hydrogen 3.505 N/A ARG 229.A NH1 GLU 233.A OE1 no hydrogen 3.002 N/A ARG 229.A NH1 GLU 233.A OE2 no hydrogen 2.922 N/A ARG 229.A NH2 GLU 233.A OE1 no hydrogen 2.785 N/A GLN 231.A N ASP 162.A OD2 no hydrogen 3.025 N/A GLN 231.A NE2 ARG 229.A O no hydrogen 3.176 N/A LYS 232.A N VAL 230.A O no hydrogen 2.495 N/A GLU 233.A N GLU 233.A OE1 no hydrogen 3.148 N/A ARG 234.A N GLN 231.A O no hydrogen 2.964 N/A ARG 234.A NH1 GLN 231.A OE1 no hydrogen 2.653 N/A ASP 236.A N GLU 239.A OE1 no hydrogen 2.704 N/A SER 238.A N ASP 236.A OD2 no hydrogen 3.100 N/A SER 238.A OG ASP 236.A OD2 no hydrogen 3.050 N/A GLU 239.A N ASP 236.A O no hydrogen 2.496 N/A ASN 242.A N GLU 239.A O no hydrogen 2.873 N/A ASN 242.A ND2 GLU 239.A O no hydrogen 3.444 N/A LEU 249.A N GLU 272.A O no hydrogen 2.743 N/A ARG 250.A N ASP 253.A OD2 no hydrogen 2.501 N/A ALA 251.A N ASP 276.A OD1 no hydrogen 2.828 N/A SER 252.A OG ASP 253.A OD1 no hydrogen 3.534 N/A ASP 253.A N ARG 250.A O no hydrogen 3.082 N/A LEU 254.A N ALA 251.A O no hydrogen 2.811 N/A ASN 256.A N HIS 255.A ND1 no hydrogen 2.978 N/A ALA 257.A N LEU 254.A O no hydrogen 3.168 N/A LYS 258.A NZ ASP 223.A OD2 no hydrogen 3.567 N/A MET 261.A N LYS 258.A O no hydrogen 3.003 N/A LYS 262.A N ASP 223.A O no hydrogen 3.091 N/A LYS 262.A NZ MET 261.A O no hydrogen 3.243 N/A LYS 262.A NZ PRO 281.A O no hydrogen 3.120 N/A VAL 263.A N HIS 282.A O no hydrogen 2.496 N/A LEU 264.A N LEU 225.A O no hydrogen 2.736 N/A HIS 265.A N GLN 288.A OE1 no hydrogen 2.656 N/A HIS 265.A NE2 GLU 272.A OE2 no hydrogen 2.497 N/A LEU 267.A N HIS 265.A ND1 no hydrogen 2.715 N/A ARG 269.A NH1 ASP 278.A OD1 no hydrogen 2.501 N/A ARG 269.A NH2 ASP 278.A OD1 no hydrogen 3.198 N/A ARG 269.A NH2 ASP 278.A OD2 no hydrogen 2.500 N/A VAL 270.A N GLU 272.A OE1 no hydrogen 3.022 N/A ASP 271.A N GLU 272.A OE1 no hydrogen 3.370 N/A GLU 272.A N GLU 272.A OE1 no hydrogen 3.008 N/A ALA 274.A N LEU 249.A O no hydrogen 3.180 N/A VAL 277.A N ALA 274.A O no hydrogen 2.923 N/A LYS 279.A N ASP 276.A O no hydrogen 2.930 N/A THR 280.A OG1 VAL 277.A O no hydrogen 2.767 N/A HIS 282.A ND1 MET 261.A O no hydrogen 2.494 N/A TRP 284.A N VAL 263.A O no hydrogen 3.037 N/A TRP 284.A NE1 GLU 147.A OE2 no hydrogen 3.056 N/A TYR 285.A OH ASP 278.A OD1 no hydrogen 2.393 N/A GLN 287.A N GLN 287.A OE1 no hydrogen 2.555 N/A GLN 288.A N TRP 284.A O no hydrogen 2.491 N/A GLN 288.A NE2 ASP 141.A OD1 no hydrogen 2.750 N/A ALA 289.A N TYR 285.A O no hydrogen 2.847 N/A GLY 290.A N PHE 286.A O no hydrogen 3.187 N/A ASN 291.A N GLN 287.A O no hydrogen 3.235 N/A ASN 291.A N GLN 288.A O no hydrogen 3.235 N/A GLY 292.A N ALA 289.A O no hydrogen 3.179 N/A ALA 295.A N ASN 291.A O no hydrogen 3.286 N/A ARG 296.A N GLY 292.A O no hydrogen 3.040 N/A ARG 296.A NE THR 136.A OG1 no hydrogen 3.033 N/A ARG 296.A NH1 SER 58.A OG no hydrogen 2.697 N/A ARG 296.A NH2 THR 136.A OG1 no hydrogen 2.925 N/A GLN 297.A N ILE 293.A O no hydrogen 2.577 N/A ALA 298.A N PHE 294.A O no hydrogen 2.789 N/A LEU 299.A N ALA 295.A O no hydrogen 2.816 N/A LEU 300.A N ARG 296.A O no hydrogen 2.871 N/A ALA 301.A N GLN 297.A O no hydrogen 2.700 N/A LEU 302.A N ALA 298.A O no hydrogen 2.765 N/A VAL 303.A N LEU 299.A O no hydrogen 2.785 N/A LEU 304.A N LEU 300.A O no hydrogen 2.922 N/A LEU 304.A N ALA 301.A O no hydrogen 3.227 N/A ASN 305.A N ALA 301.A O no hydrogen 2.937 N/A ASN 305.A N LEU 302.A O no hydrogen 3.337 N/A