Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 1tw2_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LEU 6.A N ALA 2.A O no hydrogen 3.364 N/A ILE 7.A N LEU 3.A O no hydrogen 3.280 N/A ARG 8.A N ARG 4.A O no hydrogen 3.119 N/A LEU 9.A N THR 5.A O no hydrogen 3.170 N/A GLY 10.A N LEU 6.A O no hydrogen 2.992 N/A SER 11.A N ARG 8.A O no hydrogen 3.338 N/A SER 11.A OG THR 14.A OG1 no hydrogen 3.299 N/A THR 14.A N SER 11.A OG no hydrogen 3.261 N/A THR 14.A OG1 SER 11.A OG no hydrogen 3.299 N/A MET 16.A N LEU 12.A O no hydrogen 3.352 N/A VAL 17.A N HIS 13.A O no hydrogen 2.757 N/A VAL 18.A N THR 14.A O no hydrogen 2.861 N/A ARG 19.A N PRO 15.A O no hydrogen 2.856 N/A ARG 19.A NH1 ASP 103.A OD2 no hydrogen 3.262 N/A ARG 19.A NH2 ASP 103.A OD2 no hydrogen 3.200 N/A THR 20.A N MET 16.A O no hydrogen 2.924 N/A ALA 21.A N VAL 17.A O no hydrogen 2.975 N/A ALA 22.A N VAL 18.A O no hydrogen 2.985 N/A THR 23.A N ARG 19.A O no hydrogen 2.997 N/A THR 23.A OG1 ARG 19.A O no hydrogen 2.734 N/A LEU 24.A N THR 20.A O no hydrogen 3.086 N/A ARG 25.A N ALA 22.A O no hydrogen 3.138 N/A LEU 26.A N ALA 21.A O no hydrogen 3.058 N/A HIS 29.A N ARG 25.A O no hydrogen 3.007 N/A ILE 30.A N LEU 26.A O no hydrogen 3.241 N/A LEU 31.A N VAL 27.A O no hydrogen 3.217 N/A ALA 32.A N ASP 28.A O no hydrogen 2.975 N/A ALA 32.A N HIS 29.A O no hydrogen 3.216 N/A GLY 33.A N ILE 30.A O no hydrogen 3.381 N/A ALA 34.A N HIS 29.A O no hydrogen 3.040 N/A ARG 35.A NE GLU 71.A OE1 no hydrogen 2.452 N/A ARG 35.A NH2 GLU 71.A OE1 no hydrogen 3.045 N/A ALA 39.A N THR 36.A OG1 no hydrogen 3.178 N/A LEU 40.A N THR 36.A O no hydrogen 3.028 N/A ALA 41.A N VAL 37.A O no hydrogen 3.008 N/A ALA 42.A N LYS 38.A O no hydrogen 3.008 N/A ARG 43.A N ALA 39.A O no hydrogen 2.917 N/A THR 44.A N LEU 40.A O no hydrogen 3.074 N/A THR 44.A OG1 LEU 40.A O no hydrogen 2.547 N/A THR 44.A OG1 ALA 41.A O no hydrogen 3.394 N/A THR 44.A OG1 THR 46.A OG1 no hydrogen 2.681 N/A ASP 45.A N ALA 42.A O no hydrogen 3.334 N/A THR 46.A N ALA 41.A O no hydrogen 2.808 N/A THR 46.A OG1 THR 44.A OG1 no hydrogen 2.681 N/A LEU 51.A N ARG 47.A O no hydrogen 2.907 N/A LEU 52.A N PRO 48.A O no hydrogen 3.099 N/A ARG 53.A N GLU 49.A O no hydrogen 3.167 N/A LEU 54.A N ALA 50.A O no hydrogen 2.983 N/A ILE 55.A N LEU 51.A O no hydrogen 2.847 N/A ARG 56.A N LEU 52.A O no hydrogen 2.899 N/A LEU 58.A N LEU 54.A O no hydrogen 3.161 N/A VAL 59.A N ILE 55.A O no hydrogen 2.924 N/A ALA 60.A N ARG 56.A O no hydrogen 3.166 N/A ILE 61.A N HIS 57.A O no hydrogen 3.133 N/A GLY 62.A N VAL 59.A O no hydrogen 3.376 N/A LEU 63.A N LEU 58.A O no hydrogen 2.883 N/A LEU 64.A N LEU 58.A O no hydrogen 2.984 N/A GLU 65.A N VAL 73.A O no hydrogen 2.979 N/A ASP 67.A N GLU 71.A O no hydrogen 2.946 N/A GLY 70.A N GLU 66.A OE2 no hydrogen 3.028 N/A GLU 71.A N ALA 68.A O no hydrogen 2.928 N/A VAL 73.A N GLU 65.A O no hydrogen 2.872 N/A THR 75.A N LEU 63.A O no hydrogen 3.294 N/A THR 75.A OG1 GLY 62.A O no hydrogen 2.492 N/A GLY 78.A N THR 75.A OG1 no hydrogen 3.161 N/A GLU 79.A N THR 75.A O no hydrogen 2.803 N/A GLU 79.A N GLU 76.A O no hydrogen 3.273 N/A LEU 80.A N VAL 77.A O no hydrogen 3.173 N/A LEU 81.A N GLY 78.A O no hydrogen 3.136 N/A ALA 82.A N GLU 79.A O no hydrogen 3.085 N/A ASP 83.A N ASP 28.A OD1 no hydrogen 2.991 N/A HIS 85.A N ALA 82.A O no hydrogen 2.925 N/A ALA 87.A N HIS 85.A ND1 no hydrogen 3.107 N/A ALA 88.A N HIS 85.A O no hydrogen 3.184 N/A ARG 90.A NE ALA 22.A O no hydrogen 3.038 N/A ARG 90.A NH1 ASP 83.A OD1 no hydrogen 3.106 N/A ARG 90.A NH2 ALA 22.A O no hydrogen 3.560 N/A TRP 92.A N ALA 88.A O no hydrogen 3.172 N/A HIS 93.A N GLN 89.A O no hydrogen 3.148 N/A HIS 93.A N ARG 90.A O no hydrogen 3.309 N/A ASP 94.A N ALA 91.A O no hydrogen 3.112 N/A LEU 95.A N THR 23.A OG1 no hydrogen 3.067 N/A THR 96.A N ASP 94.A OD2 no hydrogen 2.799 N/A GLN 97.A N ASP 94.A O no hydrogen 3.079 N/A ALA 98.A N SER 141.A OG no hydrogen 2.725 N/A ARG 101.A N GLN 97.A O no hydrogen 3.285 N/A ARG 101.A NH1 ASP 131.A OD2 no hydrogen 2.817 N/A ALA 102.A N ALA 98.A O no hydrogen 3.082 N/A ASP 103.A N VAL 99.A O no hydrogen 3.049 N/A ILE 104.A N ARG 101.A O no hydrogen 3.314 N/A SER 105.A N ALA 102.A O no hydrogen 2.813 N/A SER 105.A OG ALA 102.A O no hydrogen 2.955 N/A PHE 106.A N ASP 103.A O no hydrogen 2.884 N/A THR 107.A N ILE 104.A O no hydrogen 2.762 N/A THR 107.A OG1 ILE 104.A O no hydrogen 2.723 N/A ARG 108.A N SER 105.A O no hydrogen 3.228 N/A LEU 109.A N PHE 106.A O no hydrogen 3.008 N/A ASP 111.A N ARG 108.A O no hydrogen 3.089 N/A ILE 113.A N LEU 109.A O no hydrogen 3.101 N/A ARG 114.A N PRO 110.A O no hydrogen 3.117 N/A THR 115.A N ASP 111.A O no hydrogen 2.919 N/A THR 115.A OG1 ASP 111.A O no hydrogen 3.005 N/A GLY 116.A N ALA 112.A O no hydrogen 2.834 N/A ARG 117.A N THR 115.A OG1 no hydrogen 3.046 N/A THR 119.A N VAL 292.A O no hydrogen 2.960 N/A THR 119.A OG1 ARG 108.A O no hydrogen 3.253 N/A TYR 120.A OH ASP 131.A OD2 no hydrogen 2.496 N/A SER 122.A OG THR 119.A O no hydrogen 2.632 N/A ILE 123.A N TYR 120.A O no hydrogen 3.176 N/A TYR 124.A N TYR 120.A O no hydrogen 2.997 N/A TYR 124.A OH ARG 101.A O no hydrogen 2.740 N/A GLY 125.A N GLU 121.A O no hydrogen 2.840 N/A TYR 129.A OH ASN 243.A OD1 no hydrogen 2.642 N/A ASP 131.A N PRO 127.A O no hydrogen 3.005 N/A LEU 132.A N PHE 128.A O no hydrogen 3.271 N/A ALA 133.A N TYR 129.A O no hydrogen 3.059 N/A GLY 134.A N GLU 130.A O no hydrogen 3.244 N/A GLY 134.A N ASP 131.A O no hydrogen 3.068 N/A ARG 135.A N LEU 132.A O no hydrogen 3.366 N/A LEU 138.A N ARG 135.A O no hydrogen 2.868 N/A ARG 139.A N ARG 135.A O no hydrogen 3.047 N/A ARG 139.A NE ARG 139.A O no hydrogen 3.540 N/A ARG 139.A NE ASP 143.A OD2 no hydrogen 3.351 N/A ARG 139.A NH2 ASP 143.A OD1 no hydrogen 2.827 N/A ALA 140.A N PRO 136.A O no hydrogen 3.073 N/A SER 141.A N ASP 137.A O no hydrogen 3.325 N/A PHE 142.A N LEU 138.A O no hydrogen 2.952 N/A ASP 143.A N ARG 139.A O no hydrogen 3.067 N/A SER 144.A N ALA 140.A O no hydrogen 3.160 N/A SER 144.A OG ALA 140.A O no hydrogen 3.224 N/A LEU 145.A N SER 141.A O no hydrogen 3.030 N/A LEU 146.A N PHE 142.A O no hydrogen 3.147 N/A ALA 147.A N ASP 143.A O no hydrogen 3.130 N/A CYS 148.A N LEU 145.A O no hydrogen 3.115 N/A CYS 148.A SG LEU 145.A O no hydrogen 3.175 N/A GLN 150.A N ALA 147.A O no hydrogen 3.279 N/A VAL 152.A N ASP 149.A O no hydrogen 2.996 N/A ALA 153.A N ASP 149.A O no hydrogen 3.039 N/A ASP 155.A N VAL 152.A O no hydrogen 3.241 N/A ALA 158.A N PHE 154.A O no hydrogen 3.270 N/A ALA 159.A N ASP 155.A O no hydrogen 3.039 N/A ALA 160.A N ALA 156.A O no hydrogen 3.167 N/A ALA 160.A N PRO 157.A O no hydrogen 3.292 N/A TRP 163.A NE1 ALA 158.A O no hydrogen 3.041 N/A THR 164.A N ASP 162.A OD1 no hydrogen 3.240 N/A THR 164.A OG1 ASP 162.A OD1 no hydrogen 2.606 N/A VAL 166.A N TRP 163.A O no hydrogen 3.141 N/A ARG 167.A N ASP 233.A OD2 no hydrogen 3.220 N/A HIS 168.A N ASP 233.A OD2 no hydrogen 3.492 N/A VAL 169.A N SER 191.A O no hydrogen 3.011 N/A LEU 170.A N ALA 234.A O no hydrogen 3.048 N/A ASP 171.A N THR 193.A O no hydrogen 2.727 N/A VAL 172.A N ILE 236.A O no hydrogen 2.957 N/A GLY 173.A N LEU 195.A O no hydrogen 2.752 N/A GLY 174.A N LEU 195.A O no hydrogen 3.419 N/A GLY 175.A N GLU 196.A OE1 no hydrogen 2.981 N/A LYS 176.A NZ SER 144.A OG no hydrogen 2.951 N/A GLY 177.A N GLY 174.A O no hydrogen 3.213 N/A ALA 181.A N GLY 177.A O no hydrogen 2.900 N/A ALA 182.A N GLY 178.A O no hydrogen 3.071 N/A ALA 182.A N PHE 179.A O no hydrogen 3.137 N/A ILE 183.A N PHE 179.A O no hydrogen 3.117 N/A ALA 184.A N ALA 180.A O no hydrogen 3.039 N/A ARG 185.A N ALA 181.A O no hydrogen 3.195 N/A ARG 185.A NH2 ASP 155.A OD1 no hydrogen 3.477 N/A ARG 186.A N ALA 182.A O no hydrogen 3.210 N/A ALA 187.A N ILE 183.A O no hydrogen 2.922 N/A ALA 187.A N ALA 184.A O no hydrogen 3.312 N/A HIS 189.A NE2 TRP 163.A O no hydrogen 2.851 N/A VAL 190.A N ALA 187.A O no hydrogen 3.360 N/A SER 191.A N ARG 167.A O no hydrogen 3.156 N/A ALA 192.A N ARG 216.A O no hydrogen 2.879 N/A THR 193.A N VAL 169.A O no hydrogen 2.853 N/A VAL 194.A N ASP 218.A O no hydrogen 2.902 N/A LEU 195.A N ASP 171.A O no hydrogen 3.057 N/A GLU 196.A N VAL 220.A O no hydrogen 3.209 N/A MET 197.A N GLU 196.A OE2 no hydrogen 2.845 N/A THR 200.A OG1 ASP 143.A OD1 no hydrogen 3.253 N/A THR 200.A OG1 ASP 143.A OD2 no hydrogen 2.665 N/A VAL 201.A N MET 197.A O no hydrogen 3.102 N/A ASP 202.A N GLY 199.A O no hydrogen 3.176 N/A THR 203.A N GLY 199.A O no hydrogen 3.527 N/A ALA 204.A N THR 200.A O no hydrogen 2.918 N/A ARG 205.A N VAL 201.A O no hydrogen 2.964 N/A ARG 205.A NE VAL 219.A O no hydrogen 3.530 N/A ARG 205.A NH2 VAL 219.A O no hydrogen 3.110 N/A SER 206.A N ASP 202.A O no hydrogen 3.126 N/A SER 206.A OG ASP 202.A O no hydrogen 3.561 N/A SER 206.A OG THR 203.A O no hydrogen 2.998 N/A TYR 207.A N THR 203.A O no hydrogen 3.169 N/A TYR 207.A OH ASP 151.A OD1 no hydrogen 3.115 N/A LEU 208.A N ALA 204.A O no hydrogen 3.039 N/A LYS 209.A N ARG 205.A O no hydrogen 3.024 N/A ASP 210.A N SER 206.A O no hydrogen 3.056 N/A GLU 211.A N LEU 208.A O no hydrogen 3.248 N/A GLY 212.A N LYS 209.A O no hydrogen 3.043 N/A LEU 213.A N LEU 208.A O no hydrogen 2.985 N/A ARG 216.A N LEU 213.A O no hydrogen 3.112 N/A ARG 216.A NE VAL 190.A O no hydrogen 3.335 N/A ARG 216.A NH1 ALA 184.A O no hydrogen 3.406 N/A ARG 216.A NH2 ALA 184.A O no hydrogen 3.154 N/A ARG 216.A NH2 VAL 190.A O no hydrogen 2.829 N/A ASP 218.A N ALA 192.A O no hydrogen 2.985 N/A VAL 220.A N VAL 194.A O no hydrogen 2.823 N/A GLY 222.A N GLU 196.A O no hydrogen 3.210 N/A PHE 225.A N ASP 223.A OD1 no hydrogen 3.064 N/A GLU 226.A N ASP 223.A O no hydrogen 3.000 N/A ARG 230.A NE LYS 231.A O no hydrogen 2.951 N/A ALA 232.A N ALA 259.A O no hydrogen 3.049 N/A ASP 233.A N HIS 168.A O no hydrogen 3.059 N/A ILE 235.A N ARG 265.A O no hydrogen 3.008 N/A ILE 236.A N LEU 170.A O no hydrogen 2.845 N/A LEU 237.A N LEU 267.A O no hydrogen 2.932 N/A PHE 239.A N HIS 269.A O no hydrogen 2.825 N/A LEU 242.A N GLU 270.A OE1 no hydrogen 3.055 N/A ASN 243.A N VAL 240.A O no hydrogen 2.915 N/A TRP 244.A N LEU 241.A O no hydrogen 3.072 N/A ALA 249.A N PRO 245.A O no hydrogen 3.082 N/A VAL 250.A N ASP 246.A O no hydrogen 2.902 N/A ARG 251.A N HIS 247.A O no hydrogen 3.119 N/A ARG 251.A NH1 ASP 248.A OD1 no hydrogen 2.810 N/A ILE 252.A N ASP 248.A O no hydrogen 3.054 N/A LEU 253.A N ALA 249.A O no hydrogen 3.120 N/A THR 254.A N VAL 250.A O no hydrogen 2.988 N/A THR 254.A OG1 VAL 250.A O no hydrogen 2.709 N/A ARG 255.A N ARG 251.A O no hydrogen 3.120 N/A ARG 255.A NE PHE 225.A O no hydrogen 3.017 N/A ARG 255.A NH1 GLU 258.A OE1 no hydrogen 3.324 N/A ARG 255.A NH2 PHE 225.A O no hydrogen 3.293 N/A CYS 256.A N ILE 252.A O no hydrogen 3.181 N/A CYS 256.A SG ILE 252.A O no hydrogen 3.353 N/A ALA 257.A N LEU 253.A O no hydrogen 3.043 N/A GLU 258.A N THR 254.A O no hydrogen 3.081 N/A ALA 259.A N CYS 256.A O no hydrogen 2.980 N/A LEU 260.A N ALA 257.A O no hydrogen 3.292 N/A GLU 261.A N ALA 232.A O no hydrogen 3.159 N/A GLY 264.A N GLU 261.A O no hydrogen 3.070 N/A ARG 265.A N ASP 233.A O no hydrogen 3.073 N/A ARG 265.A NH1 GLY 264.A O no hydrogen 3.164 N/A ILE 266.A N LEU 335.A O no hydrogen 2.904 N/A LEU 267.A N ILE 235.A O no hydrogen 2.910 N/A ILE 268.A N LEU 333.A O no hydrogen 2.761 N/A HIS 269.A N LEU 237.A O no hydrogen 2.987 N/A ARG 271.A NE ASP 272.A O no hydrogen 2.888 N/A ARG 271.A NE ASP 273.A OD2 no hydrogen 3.242 N/A ARG 271.A NH1 GLN 282.A OE1 no hydrogen 2.668 N/A ARG 271.A NH1 ASP 329.A O no hydrogen 3.085 N/A ARG 271.A NH2 ASP 273.A OD2 no hydrogen 2.704 N/A ASP 272.A N SER 331.A OG no hydrogen 2.813 N/A HIS 275.A N GLU 302.A OE1 no hydrogen 3.230 N/A ASN 277.A N LEU 274.A O no hydrogen 2.970 N/A SER 278.A N HIS 275.A O no hydrogen 2.931 N/A SER 278.A OG HIS 275.A O no hydrogen 2.656 N/A ASN 280.A N SER 278.A O no hydrogen 2.890 N/A ASN 280.A ND2 ASP 273.A OD2 no hydrogen 3.095 N/A ASN 280.A ND2 ASN 277.A O no hydrogen 2.763 N/A PHE 283.A N ASN 280.A OD1 no hydrogen 2.791 N/A THR 284.A N ASN 280.A O no hydrogen 3.129 N/A THR 284.A OG1 ASN 280.A O no hydrogen 2.712 N/A GLU 285.A N GLU 281.A O no hydrogen 3.058 N/A ASP 287.A N PHE 283.A O no hydrogen 2.960 N/A LEU 288.A N THR 284.A O no hydrogen 3.009 N/A ARG 289.A NE ASP 103.A OD1 no hydrogen 2.880 N/A ARG 289.A NH2 ASP 103.A OD1 no hydrogen 3.152 N/A MET 290.A N LEU 286.A O no hydrogen 3.037 N/A LEU 291.A N ASP 287.A O no hydrogen 3.130 N/A VAL 292.A N LEU 288.A O no hydrogen 3.194 N/A PHE 293.A N ARG 289.A O no hydrogen 2.786 N/A LEU 294.A N MET 290.A O no hydrogen 3.119 N/A GLY 295.A N LEU 291.A O no hydrogen 3.067 N/A GLY 296.A N MET 290.A O no hydrogen 2.913 N/A ALA 297.A N LEU 242.A O no hydrogen 2.964 N/A LEU 298.A N ASP 287.A OD1 no hydrogen 3.092 N/A ARG 299.A NH1 TRP 244.A O no hydrogen 3.527 N/A ARG 299.A NH2 TRP 244.A O no hydrogen 3.325 N/A THR 300.A OG1 GLU 302.A OE1 no hydrogen 3.570 N/A ARG 301.A N ASP 273.A O no hydrogen 3.090 N/A ARG 301.A NE ASP 272.A OD2 no hydrogen 2.584 N/A ARG 301.A NH2 ASP 272.A OD1 no hydrogen 3.171 N/A GLU 302.A N GLU 302.A OE1 no hydrogen 2.857 N/A LYS 303.A N THR 300.A OG1 no hydrogen 3.311 N/A TRP 304.A N THR 300.A O no hydrogen 2.955 N/A TRP 304.A N ARG 301.A O no hydrogen 3.052 N/A ASP 305.A N ARG 301.A O no hydrogen 3.377 N/A ASP 305.A N GLU 302.A O no hydrogen 3.264 N/A LEU 307.A N LYS 303.A O no hydrogen 3.367 N/A ALA 308.A N TRP 304.A O no hydrogen 2.919 N/A ALA 309.A N ASP 305.A O no hydrogen 3.068 N/A SER 310.A N GLY 306.A O no hydrogen 3.120 N/A SER 310.A OG GLY 306.A O no hydrogen 2.875 N/A ALA 311.A N ALA 308.A O no hydrogen 3.077 N/A GLY 312.A N ALA 309.A O no hydrogen 2.884 N/A LEU 313.A N ALA 308.A O no hydrogen 2.869 N/A VAL 314.A N ALA 336.A O no hydrogen 2.901 N/A GLU 316.A N VAL 334.A O no hydrogen 2.858 N/A ARG 319.A N LEU 332.A O no hydrogen 3.335 N/A GLN 320.A NE2 ASP 273.A OD1 no hydrogen 3.287 N/A LEU 321.A N LEU 330.A O no hydrogen 2.812 N/A SER 323.A N TYR 328.A O no hydrogen 2.972 N/A THR 325.A N SER 323.A OG no hydrogen 3.170 N/A THR 325.A OG1 ASP 149.A OD1 no hydrogen 2.270 N/A THR 325.A OG1 ASP 149.A OD2 no hydrogen 3.039 N/A ILE 326.A N SER 323.A OG no hydrogen 3.316 N/A TYR 328.A OH GLN 282.A O no hydrogen 2.630 N/A ASP 329.A N GLN 282.A OE1 no hydrogen 3.189 N/A LEU 330.A N LEU 321.A O no hydrogen 2.716 N/A SER 331.A N GLU 270.A O no hydrogen 2.793 N/A SER 331.A OG ASP 272.A OD1 no hydrogen 3.231 N/A LEU 332.A N ARG 319.A O no hydrogen 3.113 N/A LEU 333.A N ILE 268.A O no hydrogen 2.783 N/A VAL 334.A N GLU 317.A O no hydrogen 3.087 N/A LEU 335.A N ILE 266.A O no hydrogen 2.797 N/A ALA 336.A N VAL 314.A O no hydrogen 3.071 N/A ALA 338.A N GLY 312.A O no hydrogen 3.201 N/A