Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 1x19_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 2.A OG ASN 15.A O no hydrogen 2.901 N/A LEU 5.A N SER 3.A O no hydrogen 2.325 N/A VAL 6.A N MET 13.A O no hydrogen 3.041 N/A ARG 8.A N HIS 11.A O no hydrogen 2.828 N/A HIS 11.A N ARG 8.A O no hydrogen 2.931 N/A MET 13.A N VAL 6.A O no hydrogen 2.956 N/A ASN 15.A ND2 SER 3.A O no hydrogen 2.345 N/A ASP 17.A N ASN 15.A O no hydrogen 2.944 N/A LEU 18.A N SER 2.A O no hydrogen 3.069 N/A ASN 20.A N ASN 16.A O no hydrogen 2.896 N/A ASN 20.A N ASP 17.A O no hydrogen 2.889 N/A TYR 21.A N ASP 17.A O no hydrogen 3.095 N/A TYR 21.A N LEU 18.A O no hydrogen 3.073 N/A TYR 22.A N LEU 18.A O no hydrogen 2.988 N/A HIS 23.A N LEU 19.A O no hydrogen 3.145 N/A ARG 24.A N ASN 20.A O no hydrogen 2.937 N/A ARG 24.A NH1 GLU 27.A OE2 no hydrogen 3.380 N/A ALA 25.A N TYR 21.A O no hydrogen 2.857 N/A ASN 26.A N TYR 22.A O no hydrogen 2.967 N/A GLU 27.A N HIS 23.A O no hydrogen 2.902 N/A LEU 28.A N ARG 24.A O no hydrogen 3.053 N/A VAL 29.A N ALA 25.A O no hydrogen 3.039 N/A PHE 30.A N ASN 26.A O no hydrogen 2.817 N/A LYS 31.A N ASN 26.A O no hydrogen 3.369 N/A GLY 32.A N GLU 27.A O no hydrogen 3.095 N/A ILE 34.A N PHE 30.A O no hydrogen 2.829 N/A GLU 35.A N LYS 31.A O no hydrogen 2.794 N/A PHE 36.A N GLY 32.A O no hydrogen 2.959 N/A SER 37.A N LEU 33.A O no hydrogen 2.793 N/A SER 37.A OG LEU 33.A O no hydrogen 2.781 N/A CYS 38.A N ILE 34.A O no hydrogen 2.900 N/A CYS 38.A SG ILE 34.A O no hydrogen 3.393 N/A MET 39.A N GLU 35.A O no hydrogen 3.118 N/A LYS 40.A N PHE 36.A O no hydrogen 2.768 N/A LYS 40.A NZ GLU 44.A OE1 no hydrogen 3.330 N/A LYS 40.A NZ GLU 44.A OE2 no hydrogen 2.476 N/A LYS 40.A NZ ASP 125.A OD1 no hydrogen 2.789 N/A ALA 41.A N SER 37.A O no hydrogen 2.934 N/A ALA 42.A N CYS 38.A O no hydrogen 2.980 N/A ILE 43.A N MET 39.A O no hydrogen 3.034 N/A GLU 44.A N LYS 40.A O no hydrogen 3.028 N/A LEU 45.A N ALA 41.A O no hydrogen 2.899 N/A ASP 46.A N ILE 43.A O no hydrogen 2.923 N/A LEU 47.A N ALA 42.A O no hydrogen 2.752 N/A HIS 50.A N ASP 46.A O no hydrogen 3.267 N/A HIS 50.A ND1 ASP 46.A O no hydrogen 3.147 N/A MET 51.A N LEU 47.A O no hydrogen 3.019 N/A ALA 52.A N PHE 48.A O no hydrogen 2.708 N/A GLY 54.A N MET 51.A O no hydrogen 2.927 N/A LYS 56.A N TRP 92.A O no hydrogen 2.921 N/A LYS 56.A NZ HIS 50.A O no hydrogen 2.928 N/A LYS 56.A NZ ASP 64.A OD2 no hydrogen 3.085 N/A THR 60.A N ASP 57.A O no hydrogen 3.219 N/A THR 60.A N ASP 57.A OD1 no hydrogen 2.682 N/A THR 60.A OG1 ASP 57.A OD1 no hydrogen 2.504 N/A LEU 61.A N ASP 57.A O no hydrogen 3.204 N/A ALA 62.A N LEU 58.A O no hydrogen 2.842 N/A ALA 63.A N ALA 59.A O no hydrogen 3.196 N/A ASP 64.A N THR 60.A O no hydrogen 2.822 N/A THR 65.A N LEU 61.A O no hydrogen 3.052 N/A THR 65.A OG1 LEU 61.A O no hydrogen 2.742 N/A THR 65.A OG1 SER 67.A OG no hydrogen 2.435 N/A GLY 66.A N ALA 63.A O no hydrogen 3.349 N/A SER 67.A N ALA 62.A O no hydrogen 3.134 N/A SER 67.A OG THR 65.A OG1 no hydrogen 2.435 N/A LEU 72.A N VAL 68.A O no hydrogen 2.936 N/A GLU 73.A N PRO 69.A O no hydrogen 3.022 N/A MET 74.A N ARG 71.A O no hydrogen 3.156 N/A LEU 76.A N LEU 72.A O no hydrogen 2.908 N/A GLU 77.A N GLU 73.A O no hydrogen 2.836 N/A THR 78.A N MET 74.A O no hydrogen 3.102 N/A THR 78.A OG1 MET 74.A O no hydrogen 2.924 N/A LEU 79.A N LEU 75.A O no hydrogen 2.974 N/A ARG 80.A N LEU 76.A O no hydrogen 2.617 N/A ARG 80.A NH2 GLU 77.A OE1 no hydrogen 2.322 N/A ARG 80.A NH2 GLU 77.A OE2 no hydrogen 3.110 N/A GLN 81.A N GLU 77.A O no hydrogen 3.006 N/A GLN 81.A NE2 GLU 77.A OE2 no hydrogen 2.557 N/A MET 82.A N THR 78.A O no hydrogen 2.946 N/A ARG 83.A N ARG 80.A O no hydrogen 2.785 N/A VAL 84.A N LEU 79.A O no hydrogen 2.959 N/A ILE 85.A N LEU 79.A O no hydrogen 3.358 N/A ASN 86.A N SER 93.A O no hydrogen 2.913 N/A GLU 88.A N LYS 91.A O no hydrogen 2.997 N/A LYS 91.A N GLU 88.A O no hydrogen 2.969 N/A TRP 92.A N LYS 56.A O no hydrogen 2.694 N/A SER 93.A N ASN 86.A O no hydrogen 2.960 N/A THR 95.A N VAL 84.A O no hydrogen 3.125 N/A ASP 99.A N THR 95.A O no hydrogen 2.823 N/A TYR 100.A N GLU 96.A O no hydrogen 3.108 N/A TYR 100.A OH GLU 108.A OE2 no hydrogen 2.842 N/A MET 101.A N PHE 97.A O no hydrogen 2.850 N/A PHE 102.A N ALA 98.A O no hydrogen 2.804 N/A SER 103.A OG ASP 99.A O no hydrogen 3.368 N/A LYS 107.A NZ ASP 99.A OD1 no hydrogen 3.394 N/A LYS 107.A NZ ASP 99.A OD2 no hydrogen 2.874 N/A ASN 110.A ND2 ARG 163.A O no hydrogen 2.837 N/A ASN 110.A ND2 ASP 194.A OD2 no hydrogen 2.931 N/A LEU 111.A N GLU 108.A O no hydrogen 3.440 N/A HIS 112.A N SER 164.A O no hydrogen 2.962 N/A HIS 112.A NE2 SER 103.A O no hydrogen 2.888 N/A GLN 113.A N MET 101.A O no hydrogen 2.679 N/A THR 114.A OG1 SER 103.A O no hydrogen 2.776 N/A THR 114.A OG1 HIS 112.A NE2 no hydrogen 3.405 N/A ALA 117.A N GLN 113.A O no hydrogen 2.849 N/A LYS 118.A N THR 114.A O no hydrogen 2.916 N/A ALA 119.A N PRO 115.A O no hydrogen 3.191 N/A MET 120.A N VAL 116.A O no hydrogen 2.803 N/A ALA 121.A N ALA 117.A O no hydrogen 2.774 N/A PHE 122.A N LYS 118.A O no hydrogen 3.143 N/A LEU 123.A N ALA 119.A O no hydrogen 2.901 N/A ALA 124.A N MET 120.A O no hydrogen 2.887 N/A ASP 126.A N PHE 122.A O no hydrogen 2.922 N/A PHE 127.A N LEU 123.A O no hydrogen 2.806 N/A TYR 128.A N LEU 123.A O no hydrogen 2.965 N/A TYR 128.A OH SER 301.A O no hydrogen 2.772 N/A MET 129.A N ALA 124.A O no hydrogen 2.995 N/A GLY 130.A N PHE 127.A O no hydrogen 2.909 N/A LEU 131.A N TYR 128.A O no hydrogen 3.213 N/A ALA 134.A N GLY 130.A O no hydrogen 3.045 N/A VAL 135.A N LEU 131.A O no hydrogen 2.777 N/A ARG 136.A N SER 132.A O no hydrogen 3.121 N/A GLY 137.A N ALA 134.A O no hydrogen 2.914 N/A GLN 138.A N GLN 133.A O no hydrogen 2.870 N/A LYS 139.A NZ ASP 126.A O no hydrogen 3.088 N/A PHE 141.A N GLY 308.A O no hydrogen 2.858 N/A GLY 143.A N ASP 126.A OD1 no hydrogen 3.127 N/A ARG 152.A NH1 GLU 222.A OE1 no hydrogen 3.527 N/A ARG 152.A NH1 GLU 222.A OE2 no hydrogen 2.700 N/A ARG 152.A NH2 GLU 222.A OE1 no hydrogen 2.840 N/A ARG 152.A NH2 GLU 222.A OE2 no hydrogen 3.290 N/A ASN 155.A N THR 151.A O no hydrogen 2.842 N/A ASN 155.A ND2 THR 151.A O no hydrogen 2.914 N/A LEU 156.A N ARG 152.A O no hydrogen 2.882 N/A TYR 157.A N GLU 153.A O no hydrogen 2.993 N/A PHE 158.A N ASP 154.A O no hydrogen 3.189 N/A GLU 159.A N ASN 155.A O no hydrogen 2.864 N/A GLU 160.A N LEU 156.A O no hydrogen 2.963 N/A HIS 162.A N PHE 158.A O no hydrogen 2.908 N/A ARG 163.A N GLU 159.A O no hydrogen 2.926 N/A ARG 163.A NE ASP 194.A OD2 no hydrogen 2.903 N/A ARG 163.A NH1 ASP 194.A OD1 no hydrogen 3.058 N/A ARG 163.A NH1 ASP 194.A OD2 no hydrogen 3.453 N/A SER 164.A N GLU 160.A O no hydrogen 3.157 N/A SER 164.A N ILE 161.A O no hydrogen 3.134 N/A SER 164.A OG GLU 160.A O no hydrogen 2.879 N/A ASN 165.A ND2 HIS 162.A O no hydrogen 2.843 N/A ALA 166.A N ARG 163.A O no hydrogen 3.435 N/A LYS 167.A N ASN 110.A O no hydrogen 2.804 N/A LYS 167.A NZ GLU 108.A OE1 no hydrogen 2.532 N/A ILE 170.A N ALA 166.A O no hydrogen 3.063 N/A GLN 171.A N LYS 167.A O no hydrogen 2.909 N/A LEU 172.A N PHE 168.A O no hydrogen 2.958 N/A LEU 173.A N ALA 169.A O no hydrogen 3.090 N/A LEU 174.A N ILE 170.A O no hydrogen 2.835 N/A GLU 175.A N GLN 171.A O no hydrogen 3.069 N/A GLU 176.A N LEU 172.A O no hydrogen 2.958 N/A ALA 177.A N LEU 173.A O no hydrogen 2.762 N/A VAL 182.A N LEU 179.A O no hydrogen 3.054 N/A LYS 183.A N ASP 249.A OD2 no hydrogen 2.832 N/A LYS 183.A NZ GLU 205.A OE2 no hydrogen 2.921 N/A LYS 184.A N ASP 249.A OD2 no hydrogen 3.009 N/A LYS 184.A NZ GLU 247.A O no hydrogen 2.931 N/A MET 185.A N ASP 207.A O no hydrogen 2.776 N/A ILE 186.A N ALA 250.A O no hydrogen 3.134 N/A ASP 187.A N THR 209.A O no hydrogen 2.854 N/A VAL 188.A N LEU 252.A O no hydrogen 2.861 N/A ILE 192.A N GLU 159.A OE1 no hydrogen 3.027 N/A GLY 193.A N GLY 190.A O no hydrogen 3.121 N/A SER 196.A OG ASP 187.A OD1 no hydrogen 2.601 N/A SER 196.A OG SER 208.A OG no hydrogen 2.828 N/A ALA 197.A N GLY 193.A O no hydrogen 2.951 N/A ALA 198.A N ASP 194.A O no hydrogen 3.108 N/A MET 199.A N ILE 195.A O no hydrogen 3.155 N/A LEU 200.A N SER 196.A O no hydrogen 2.989 N/A LEU 200.A N ALA 197.A O no hydrogen 2.841 N/A LYS 201.A N ALA 197.A O no hydrogen 3.306 N/A LYS 201.A N ALA 198.A O no hydrogen 3.012 N/A HIS 202.A N MET 199.A O no hydrogen 3.060 N/A HIS 202.A ND1 ALA 198.A O no hydrogen 3.370 N/A LEU 206.A N PHE 203.A O no hydrogen 2.865 N/A ASP 207.A N LYS 183.A O no hydrogen 2.757 N/A SER 208.A N ARG 232.A O no hydrogen 2.737 N/A SER 208.A OG SER 196.A OG no hydrogen 2.828 N/A THR 209.A N MET 185.A O no hydrogen 3.048 N/A ILE 210.A N ARG 234.A O no hydrogen 2.759 N/A LEU 211.A N ASP 187.A O no hydrogen 2.825 N/A ASN 212.A N ILE 236.A O no hydrogen 3.036 N/A LEU 213.A N ASN 212.A OD1 no hydrogen 2.790 N/A ALA 216.A N LEU 213.A O no hydrogen 2.747 N/A ILE 217.A N PRO 214.A O no hydrogen 3.473 N/A LEU 219.A N ALA 216.A O no hydrogen 2.819 N/A VAL 220.A N ALA 216.A O no hydrogen 3.061 N/A ASN 221.A N ILE 217.A O no hydrogen 2.992 N/A GLU 222.A N ASP 218.A O no hydrogen 2.953 N/A ASN 223.A N LEU 219.A O no hydrogen 2.944 N/A ASN 223.A ND2 ILE 192.A O no hydrogen 2.988 N/A ASN 223.A ND2 ASP 194.A OD1 no hydrogen 2.845 N/A ALA 224.A N VAL 220.A O no hydrogen 2.830 N/A ALA 225.A N ASN 221.A O no hydrogen 2.985 N/A GLU 226.A N GLU 222.A O no hydrogen 2.830 N/A LYS 227.A N ASN 223.A O no hydrogen 2.947 N/A LYS 227.A NZ ASP 194.A OD1 no hydrogen 3.226 N/A LYS 227.A NZ ASN 223.A OD1 no hydrogen 2.922 N/A GLY 228.A N ALA 225.A O no hydrogen 2.960 N/A VAL 229.A N ALA 224.A O no hydrogen 2.869 N/A ARG 232.A N VAL 229.A O no hydrogen 2.897 N/A ARG 232.A NE LEU 206.A O no hydrogen 3.260 N/A ARG 232.A NH1 LEU 200.A O no hydrogen 3.071 N/A ARG 232.A NH1 LEU 206.A O no hydrogen 3.020 N/A ARG 232.A NH2 LEU 200.A O no hydrogen 3.115 N/A MET 233.A N VAL 229.A O no hydrogen 2.857 N/A ARG 234.A N SER 208.A O no hydrogen 3.153 N/A ARG 234.A NH1 ASP 207.A OD1 no hydrogen 2.892 N/A ARG 234.A NH1 THR 209.A OG1 no hydrogen 2.858 N/A ARG 234.A NH2 ASP 207.A OD2 no hydrogen 2.868 N/A GLY 235.A N ASN 221.A OD1 no hydrogen 3.289 N/A ILE 236.A N ILE 210.A O no hydrogen 2.889 N/A ASP 239.A N GLU 243.A OE2 no hydrogen 2.862 N/A LYS 242.A N ASP 239.A OD2 no hydrogen 2.516 N/A GLU 243.A N ASP 239.A O no hydrogen 3.248 N/A TYR 245.A OH ILE 240.A O no hydrogen 2.754 N/A ASP 249.A N LYS 184.A O no hydrogen 2.588 N/A VAL 251.A N ARG 281.A O no hydrogen 3.136 N/A LEU 252.A N ILE 186.A O no hydrogen 3.072 N/A PHE 253.A N LEU 283.A O no hydrogen 2.841 N/A CYS 254.A N VAL 188.A O no hydrogen 3.187 N/A ARG 255.A N LEU 285.A O no hydrogen 2.632 N/A ARG 255.A NH2 HIS 162.A O no hydrogen 3.121 N/A ALA 260.A N LEU 257.A O no hydrogen 3.083 N/A LEU 264.A N ASN 261.A OD1 no hydrogen 3.087 N/A SER 265.A N ASN 261.A O no hydrogen 3.203 N/A SER 265.A OG ALA 260.A O no hydrogen 3.405 N/A SER 265.A OG ASN 261.A O no hydrogen 2.973 N/A THR 266.A N GLU 262.A O no hydrogen 3.001 N/A THR 266.A OG1 GLU 262.A O no hydrogen 2.730 N/A ILE 267.A N GLN 263.A O no hydrogen 3.068 N/A MET 268.A N LEU 264.A O no hydrogen 2.735 N/A CYS 269.A N SER 265.A O no hydrogen 2.870 N/A CYS 269.A SG SER 265.A O no hydrogen 3.375 N/A LYS 270.A N THR 266.A O no hydrogen 2.852 N/A LYS 270.A NZ ASP 274.A OD1 no hydrogen 3.045 N/A LYS 270.A NZ ASP 274.A OD2 no hydrogen 3.227 N/A LYS 271.A N ILE 267.A O no hydrogen 2.916 N/A LYS 271.A NZ TYR 241.A O no hydrogen 2.636 N/A ALA 272.A N MET 268.A O no hydrogen 3.060 N/A PHE 273.A N CYS 269.A O no hydrogen 2.902 N/A ASP 274.A N LYS 270.A O no hydrogen 2.686 N/A ALA 275.A N ALA 272.A O no hydrogen 3.097 N/A MET 276.A N ALA 272.A O no hydrogen 3.037 N/A MET 276.A N PHE 273.A O no hydrogen 2.984 N/A SER 278.A OG PRO 350.A OXT no hydrogen 2.839 N/A GLY 279.A N LYS 349.A O no hydrogen 2.738 N/A GLY 280.A N ARG 277.A O no hydrogen 2.833 N/A ARG 281.A N ASP 249.A O no hydrogen 2.984 N/A ARG 281.A NE GLY 279.A O no hydrogen 3.496 N/A ARG 281.A NH1 ASP 180.A OD1 no hydrogen 3.311 N/A ARG 281.A NH2 LYS 178.A O no hydrogen 3.082 N/A ARG 281.A NH2 ASP 180.A OD2 no hydrogen 3.360 N/A LEU 282.A N ALA 347.A O no hydrogen 2.887 N/A LEU 283.A N VAL 251.A O no hydrogen 2.960 N/A ILE 284.A N VAL 345.A O no hydrogen 2.905 N/A LEU 285.A N PHE 253.A O no hydrogen 3.145 N/A ASP 286.A N LEU 343.A O no hydrogen 2.852 N/A VAL 288.A N ASP 341.A O no hydrogen 2.700 N/A GLU 293.A N ASP 291.A OD1 no hydrogen 2.650 N/A ASN 294.A N ASP 291.A O no hydrogen 3.137 N/A ASN 294.A ND2 ASP 291.A OD2 no hydrogen 2.941 N/A ASN 296.A ND2 VAL 288.A O no hydrogen 3.206 N/A TYR 299.A N ASN 296.A OD1 no hydrogen 2.882 N/A TYR 299.A OH GLY 315.A O no hydrogen 2.678 N/A LEU 300.A N ASN 296.A O no hydrogen 2.890 N/A SER 301.A N PHE 297.A O no hydrogen 2.716 N/A SER 301.A OG ASP 298.A O no hydrogen 2.581 N/A HIS 302.A N TYR 299.A O no hydrogen 2.984 N/A TYR 303.A N TYR 299.A O no hydrogen 2.739 N/A ILE 304.A N LEU 300.A O no hydrogen 2.649 N/A LEU 305.A N HIS 302.A O no hydrogen 3.085 N/A GLY 306.A N TYR 303.A O no hydrogen 3.019 N/A ALA 307.A N ILE 304.A O no hydrogen 2.824 N/A GLY 308.A N LEU 305.A O no hydrogen 2.674 N/A MET 309.A N GLY 306.A O no hydrogen 3.166 N/A LEU 314.A N SER 312.A OG no hydrogen 3.140 N/A GLY 315.A N SER 259.A O no hydrogen 3.239 N/A LYS 317.A NZ LEU 257.A O no hydrogen 2.910 N/A LYS 317.A NZ ALA 260.A O no hydrogen 2.928 N/A LYS 317.A NZ TYR 322.A OH no hydrogen 2.931 N/A GLN 319.A N ASP 290.A OD1 no hydrogen 2.892 N/A ARG 321.A N GLU 318.A O no hydrogen 2.994 N/A TYR 322.A N GLN 319.A O no hydrogen 3.117 N/A TYR 322.A OH ASP 286.A OD2 no hydrogen 2.416 N/A LYS 323.A N ALA 320.A O no hydrogen 3.179 N/A GLU 324.A N GLU 324.A OE1 no hydrogen 2.800 N/A ILE 325.A N ARG 321.A O no hydrogen 3.153 N/A LEU 326.A N TYR 322.A O no hydrogen 2.750 N/A GLU 327.A N LYS 323.A O no hydrogen 2.807 N/A SER 328.A N GLU 324.A O no hydrogen 2.819 N/A SER 328.A OG ILE 325.A O no hydrogen 3.307 N/A LEU 329.A N ILE 325.A O no hydrogen 3.174 N/A LEU 329.A N LEU 326.A O no hydrogen 2.856 N/A GLY 330.A N LEU 326.A O no hydrogen 3.107 N/A GLY 330.A N GLU 327.A O no hydrogen 2.980 N/A TYR 331.A N LEU 326.A O no hydrogen 3.013 N/A TYR 331.A OH CYS 269.A O no hydrogen 2.581 N/A LYS 332.A N VAL 348.A O no hydrogen 2.838 N/A THR 335.A N GLN 346.A O no hydrogen 2.820 N/A VAL 337.A N LEU 344.A O no hydrogen 3.014 N/A ARG 338.A NH1 ASP 290.A OD2 no hydrogen 3.036 N/A ARG 338.A NH2 ASP 290.A OD1 no hydrogen 2.996 N/A LYS 339.A N HIS 342.A O no hydrogen 2.955 N/A LYS 339.A NZ TYR 340.A OH no hydrogen 2.944 N/A TYR 340.A OH GLU 175.A OE1 no hydrogen 2.711 N/A TYR 340.A OH GLU 175.A OE2 no hydrogen 3.188 N/A HIS 342.A N LYS 339.A O no hydrogen 2.897 N/A HIS 342.A ND1 TYR 340.A O no hydrogen 2.823 N/A LEU 343.A N ASP 286.A O no hydrogen 2.879 N/A LEU 344.A N VAL 337.A O no hydrogen 2.884 N/A VAL 345.A N ILE 284.A O no hydrogen 2.875 N/A GLN 346.A N THR 335.A O no hydrogen 2.975 N/A ALA 347.A N LEU 282.A O no hydrogen 3.098 N/A VAL 348.A N LYS 332.A O no hydrogen 3.015 N/A LYS 349.A N GLY 280.A O no hydrogen 2.879 N/A LYS 349.A NZ PHE 273.A O no hydrogen 3.162 N/A LYS 349.A NZ MET 276.A O no hydrogen 2.617 N/A