Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 1zx5_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LEU 3.A N GLU 69.A OE2 no hydrogen 2.931 N/A SER 5.A N GLU 261.A OE1 no hydrogen 3.050 N/A SER 5.A OG THR 277.A OG1 no hydrogen 2.707 N/A PHE 6.A N GLU 261.A OE2 no hydrogen 3.043 N/A ILE 7.A N LEU 272.A O no hydrogen 2.850 N/A GLN 9.A NE2 TRP 39.A O no hydrogen 3.162 N/A ALA 10.A N THR 50.A O no hydrogen 2.801 N/A ASN 13.A ND2 ARG 47.A O no hydrogen 2.918 N/A ASN 13.A ND2 SER 49.A OG no hydrogen 3.093 N/A VAL 15.A N GLU 37.A O no hydrogen 2.932 N/A ARG 17.A N GLY 34.A O no hydrogen 2.809 N/A ARG 17.A NE GLU 37.A OE2 no hydrogen 2.805 N/A ARG 17.A NH2 GLU 37.A OE2 no hydrogen 2.880 N/A GLY 20.A N ARG 17.A O no hydrogen 3.097 N/A GLY 21.A N ASP 89.A OD2 no hydrogen 2.952 N/A LEU 26.A N GLU 22.A O no hydrogen 3.223 N/A LEU 27.A N TRP 23.A O no hydrogen 2.944 N/A LYS 28.A N ILE 24.A O no hydrogen 3.022 N/A LYS 28.A NZ GLU 40.A OE2 no hydrogen 2.865 N/A LYS 28.A NZ GLY 268.A O no hydrogen 2.730 N/A GLY 29.A N LEU 26.A O no hydrogen 3.055 N/A PHE 30.A N ALA 25.A O no hydrogen 2.880 N/A GLN 32.A NE2 SER 33.A O no hydrogen 2.962 N/A GLY 34.A N GLY 21.A O no hydrogen 3.107 N/A GLY 36.A N VAL 15.A O no hydrogen 2.886 N/A GLU 37.A N VAL 15.A O no hydrogen 3.298 N/A SER 38.A N LEU 87.A O no hydrogen 2.911 N/A SER 38.A OG GLU 40.A OE2 no hydrogen 2.562 N/A TRP 39.A N ASN 13.A O no hydrogen 2.823 N/A TRP 39.A NE1 GLU 37.A OE1 no hydrogen 2.754 N/A GLU 40.A N VAL 85.A O no hydrogen 2.809 N/A SER 42.A N SER 49.A OG no hydrogen 3.027 N/A SER 42.A OG ARG 47.A O no hydrogen 2.744 N/A HIS 44.A N SER 42.A OG no hydrogen 3.012 N/A HIS 44.A NE2 GLU 112.A OE1 no hydrogen 2.657 N/A SER 46.A N HIS 44.A ND1 no hydrogen 3.236 N/A SER 46.A OG HIS 44.A ND1 no hydrogen 2.809 N/A ARG 47.A N HIS 44.A O no hydrogen 2.891 N/A SER 49.A N SER 42.A O no hydrogen 2.791 N/A SER 49.A OG TRP 39.A O no hydrogen 3.204 N/A THR 50.A OG1 GLN 11.A OE1.B no hydrogen 3.405 N/A VAL 51.A N LEU 58.A O no hydrogen 2.605 N/A LEU 52.A N PHE 8.A O no hydrogen 2.815 N/A VAL 53.A N GLN 56.A O.A no hydrogen 2.788 N/A VAL 53.A N GLN 56.A O.B no hydrogen 2.774 N/A GLN 56.A N.A VAL 53.A O no hydrogen 3.165 N/A GLN 56.A N.B VAL 53.A O no hydrogen 3.167 N/A GLN 56.A NE2.B GLN 57.A O no hydrogen 3.508 N/A LEU 58.A N VAL 51.A O no hydrogen 2.951 N/A SER 59.A N GLU 61.A OE1.B no hydrogen 3.099 N/A LEU 62.A N SER 59.A O no hydrogen 2.856 N/A SER 64.A N ILE 60.A O no hydrogen 3.050 N/A SER 64.A OG ILE 60.A O no hydrogen 3.371 N/A SER 64.A OG GLU 61.A O.A no hydrogen 3.054 N/A SER 64.A OG GLU 61.A O.B no hydrogen 3.363 N/A LYS 65.A N GLU 61.A O.A no hydrogen 3.013 N/A LYS 65.A N GLU 61.A O.B no hydrogen 3.279 N/A LYS 65.A NZ GLU 61.A OE2.A no hydrogen 3.365 N/A HIS 66.A N LEU 62.A O no hydrogen 2.869 N/A ARG 67.A NH1 PHE 78.A O no hydrogen 2.581 N/A ARG 67.A NH2 PHE 78.A O no hydrogen 2.758 N/A LEU 70.A N HIS 66.A O no hydrogen 2.791 N/A LEU 71.A N ARG 67.A O no hydrogen 2.920 N/A GLY 72.A N ASP 68.A O no hydrogen 2.849 N/A ARG 73.A N GLY 244.A O no hydrogen 2.860 N/A ARG 73.A NE GLY 243.A O no hydrogen 2.931 N/A ARG 73.A NH2 GLY 243.A O no hydrogen 2.655 N/A ALA 74.A N LEU 71.A O no hydrogen 3.070 N/A ALA 75.A N GLY 72.A O no hydrogen 3.080 N/A LYS 77.A NZ GLU 225.A O no hydrogen 3.243 N/A LYS 77.A NZ LYS 295.A O no hydrogen 2.730 N/A PHE 78.A N ALA 74.A O no hydrogen 3.104 N/A LEU 84.A N SER 185.A O no hydrogen 2.812 N/A ARG 86.A N GLU 183.A O.A no hydrogen 3.082 N/A ARG 86.A N GLU 183.A O.B no hydrogen 2.878 N/A ARG 86.A NH1 GLU 37.A OE1 no hydrogen 2.991 N/A LEU 87.A N SER 38.A O no hydrogen 2.870 N/A ILE 88.A N VAL 181.A O no hydrogen 2.749 N/A ASP 89.A N GLY 36.A O no hydrogen 2.811 N/A ALA 90.A N LEU 179.A O no hydrogen 2.871 N/A ALA 91.A N TRP 19.A O no hydrogen 3.113 N/A SER 92.A N TRP 19.A O no hydrogen 3.207 N/A THR 94.A N GLY 176.A O no hydrogen 3.070 N/A THR 94.A OG1 GLY 176.A O no hydrogen 3.407 N/A VAL 96.A N GLN 95.A OE1 no hydrogen 2.858 N/A HIS 97.A N HIS 174.A O no hydrogen 3.051 N/A HIS 97.A ND1 GLN 95.A O no hydrogen 2.745 N/A VAL 98.A N TYR 192.A O no hydrogen 2.985 N/A HIS 99.A ND1 LEU 190.A O no hydrogen 2.686 N/A ALA 104.A N SER 101.A OG no hydrogen 3.063 N/A ALA 105.A N SER 101.A O no hydrogen 2.836 N/A GLU 106.A N ASP 102.A O no hydrogen 3.041 N/A SER 107.A N LYS 103.A O no hydrogen 2.996 N/A LEU 108.A N ALA 104.A O no hydrogen 2.824 N/A GLY 109.A N GLU 106.A O no hydrogen 3.105 N/A GLU 110.A N ALA 105.A O no hydrogen 2.936 N/A GLY 114.A N ASP 102.A OD1 no hydrogen 2.840 N/A VAL 115.A N PRO 100.A O no hydrogen 3.032 N/A GLU 116.A N SER 186.A OG no hydrogen 3.127 N/A SER 117.A N ILE 168.A O no hydrogen 3.133 N/A SER 117.A OG GLU 183.A OE2.B no hydrogen 3.372 N/A ALA 118.A N VAL 184.A O no hydrogen 2.791 N/A TRP 119.A N PHE 166.A O no hydrogen 2.817 N/A LEU 120.A N LEU 182.A O no hydrogen 2.810 N/A VAL 121.A N ASP 164.A O no hydrogen 3.000 N/A PHE 122.A N ARG 180.A O no hydrogen 2.768 N/A ASN 123.A ND2 GLY 178.A O no hydrogen 2.889 N/A GLY 125.A N THR 160.A OG1 no hydrogen 2.975 N/A LYS 126.A N GLU 177.A O no hydrogen 2.934 N/A ALA 127.A N PHE 158.A O no hydrogen 2.948 N/A TYR 128.A N ALA 175.A O no hydrogen 2.880 N/A TYR 128.A OH GLU 177.A OE1 no hydrogen 3.159 N/A ALA 129.A N ASN 156.A O no hydrogen 3.101 N/A GLY 130.A N PRO 173.A O no hydrogen 2.866 N/A LYS 132.A N LEU 154.A O no hydrogen 2.983 N/A LYS 132.A NZ THR 153.A O no hydrogen 2.763 N/A VAL 135.A N THR 208.A O no hydrogen 2.955 N/A LEU 140.A N LYS 136.A O no hydrogen 3.108 N/A GLU 141.A N ILE 137.A O no hydrogen 3.011 N/A GLU 142.A N GLU 138.A O no hydrogen 3.119 N/A LYS 143.A N GLU 139.A O no hydrogen 3.351 N/A LEU 144.A N LEU 140.A O no hydrogen 3.269 N/A LEU 144.A N GLU 141.A O no hydrogen 3.205 N/A LYS 145.A N GLU 142.A O no hydrogen 3.108 N/A LYS 145.A NZ GLU 142.A OE1 no hydrogen 3.086 N/A LYS 145.A NZ GLU 142.A OE2 no hydrogen 2.704 N/A GLU 146.A N LYS 143.A O no hydrogen 3.180 N/A LYS 152.A N ASP 150.A OD1 no hydrogen 3.227 N/A LYS 152.A NZ ASP 150.A OD1 no hydrogen 2.896 N/A LYS 152.A NZ ASP 150.A OD2 no hydrogen 3.560 N/A THR 153.A N ASP 150.A O no hydrogen 3.180 N/A THR 153.A OG1 ASP 150.A O no hydrogen 2.616 N/A LEU 154.A N PHE 151.A O no hydrogen 3.004 N/A LEU 155.A N LYS 152.A O no hydrogen 3.140 N/A ASN 156.A N GLY 130.A O no hydrogen 2.848 N/A THR 157.A OG1 LEU 155.A O no hydrogen 3.382 N/A PHE 158.A N ALA 127.A O no hydrogen 2.763 N/A THR 160.A N GLY 125.A O no hydrogen 3.002 N/A THR 160.A OG1 ASN 123.A O no hydrogen 2.821 N/A THR 160.A OG1 GLY 125.A O no hydrogen 3.410 N/A THR 161.A N ASP 164.A OD2 no hydrogen 2.950 N/A THR 161.A OG1 ASP 164.A OD1 no hydrogen 3.343 N/A TYR 163.A N VAL 121.A O no hydrogen 2.639 N/A TYR 163.A OH GLU 252.A OE2 no hydrogen 2.554 N/A ASP 164.A N THR 161.A O no hydrogen 3.210 N/A THR 165.A OG1 LYS 219.A O no hydrogen 2.731 N/A PHE 166.A N TRP 119.A O no hydrogen 3.118 N/A VAL 167.A N VAL 216.A O no hydrogen 2.813 N/A ILE 168.A N SER 117.A O no hydrogen 2.858 N/A ARG 169.A NH1 GLU 215.A O no hydrogen 2.806 N/A GLY 171.A N HIS 99.A O no hydrogen 2.850 N/A ILE 172.A N ARG 169.A O no hydrogen 3.070 N/A HIS 174.A N HIS 97.A O no hydrogen 2.943 N/A HIS 174.A ND1 ILE 172.A O no hydrogen 3.169 N/A ALA 175.A N TYR 128.A O no hydrogen 3.019 N/A GLY 176.A N THR 94.A OG1 no hydrogen 3.069 N/A GLU 177.A N LYS 126.A O no hydrogen 2.872 N/A GLY 178.A N ALA 91.A O no hydrogen 3.139 N/A LEU 179.A N ALA 90.A O no hydrogen 2.927 N/A ARG 180.A N ASN 123.A OD1 no hydrogen 2.931 N/A VAL 181.A N ILE 88.A O no hydrogen 2.981 N/A LEU 182.A N LEU 120.A O no hydrogen 2.693 N/A GLU 183.A N.A ARG 86.A O no hydrogen 2.763 N/A GLU 183.A N.B ARG 86.A O no hydrogen 2.748 N/A VAL 184.A N ALA 118.A O no hydrogen 2.874 N/A SER 185.A N LEU 84.A O no hydrogen 2.926 N/A SER 185.A OG SER 186.A O no hydrogen 2.854 N/A SER 186.A N GLU 116.A O no hydrogen 3.089 N/A SER 186.A OG GLY 114.A O no hydrogen 3.503 N/A SER 186.A OG GLU 116.A O no hydrogen 3.559 N/A ASN 187.A ND2 ALA 43.A O no hydrogen 3.675 N/A ASN 187.A ND2 PHE 81.A O no hydrogen 3.278 N/A SER 188.A N SER 186.A O no hydrogen 2.795 N/A SER 188.A OG GLY 113.A O no hydrogen 2.759 N/A THR 189.A N GLU 112.A OE1 no hydrogen 3.061 N/A THR 189.A OG1 GLU 112.A OE1 no hydrogen 3.322 N/A THR 189.A OG1 GLU 112.A OE2 no hydrogen 2.831 N/A LEU 190.A N SER 188.A OG no hydrogen 3.343 N/A TYR 192.A N VAL 98.A O no hydrogen 2.898 N/A TYR 192.A OH GLU 110.A OE2 no hydrogen 2.634 N/A PHE 193.A N ASP 198.A OD2 no hydrogen 2.810 N/A PHE 194.A N VAL 96.A O no hydrogen 2.907 N/A ASN 195.A N PHE 193.A O no hydrogen 2.838 N/A ASP 198.A N ASN 195.A O no hydrogen 3.304 N/A ASP 198.A N ASN 195.A OD1 no hydrogen 2.928 N/A TRP 199.A N GLU 196.A O no hydrogen 3.372 N/A LYS 201.A N ASP 198.A O no hydrogen 3.005 N/A LYS 201.A NZ GLU 110.A OE2 no hydrogen 3.154 N/A VAL 202.A N ASP 198.A O no hydrogen 2.993 N/A LYS 203.A N TRP 199.A O no hydrogen 2.949 N/A LYS 203.A NZ GLU 200.A OE2 no hydrogen 2.815 N/A VAL 205.A N VAL 202.A O no hydrogen 3.147 N/A LEU 206.A N VAL 202.A O no hydrogen 2.848 N/A ASN 207.A N GLY 171.A O no hydrogen 2.789 N/A LYS 209.A N ASN 207.A OD1 no hydrogen 3.008 N/A LYS 210.A N ASP 134.A OD1 no hydrogen 2.833 N/A VAL 211.A N PHE 131.A O no hydrogen 2.851 N/A GLU 212.A N GLU 215.A OE2 no hydrogen 2.772 N/A GLU 215.A N GLU 212.A O no hydrogen 2.983 N/A VAL 216.A N GLU 213.A O no hydrogen 3.052 N/A LYS 217.A N GLU 213.A O no hydrogen 3.050 N/A GLY 218.A N THR 165.A O no hydrogen 2.843 N/A LYS 220.A NZ THR 161.A OG1 no hydrogen 2.831 N/A LYS 220.A NZ PRO 162.A O no hydrogen 2.750 N/A LYS 220.A NZ ASP 164.A OD1 no hydrogen 2.797 N/A GLY 221.A N TYR 163.A O no hydrogen 2.766 N/A ALA 222.A N LEU 229.A O no hydrogen 3.182 N/A THR 224.A N PHE 227.A O no hydrogen 2.828 N/A THR 224.A OG1 GLU 116.A OE2 no hydrogen 2.918 N/A THR 224.A OG1 PHE 227.A O no hydrogen 3.490 N/A ASN 226.A N THR 224.A OG1 no hydrogen 3.160 N/A PHE 227.A N THR 224.A OG1 no hydrogen 3.384 N/A GLY 228.A N TYR 293.A O no hydrogen 2.905 N/A LEU 229.A N ALA 222.A O no hydrogen 2.916 N/A GLU 230.A N ARG 291.A O no hydrogen 2.948 N/A VAL 231.A N GLY 221.A O no hydrogen 2.788 N/A VAL 232.A N ILE 289.A O no hydrogen 2.774 N/A VAL 234.A N GLY 287.A O no hydrogen 2.801 N/A GLY 236.A N SER 284.A O no hydrogen 2.693 N/A ALA 238.A N VAL 282.A O no hydrogen 2.862 N/A ILE 240.A N PHE 280.A O no hydrogen 2.770 N/A THR 242.A N ASP 278.A O no hydrogen 3.062 N/A THR 242.A OG1 THR 277.A O no hydrogen 2.666 N/A THR 242.A OG1 ASP 278.A O no hydrogen 3.297 N/A GLY 244.A N THR 242.A OG1 no hydrogen 3.115 N/A ILE 247.A N ILE 292.A O no hydrogen 2.950 N/A LEU 248.A N CYS 271.A O no hydrogen 2.746 N/A TYR 249.A N VAL 290.A O no hydrogen 2.857 N/A ALA 250.A N TYR 269.A O no hydrogen 2.988 N/A ALA 251.A N LYS 288.A O no hydrogen 3.001 N/A GLU 252.A N LYS 288.A O no hydrogen 3.174 N/A TYR 254.A OH ASP 264.A OD2 no hydrogen 2.459 N/A PHE 255.A N LEU 265.A O no hydrogen 3.032 N/A ILE 256.A N GLU 283.A O no hydrogen 2.979 N/A LEU 257.A N ALA 263.A O no hydrogen 2.795 N/A ARG 258.A N THR 281.A O no hydrogen 2.879 N/A ARG 258.A NH1 GLU 283.A OE1 no hydrogen 2.846 N/A ARG 258.A NH2 GLU 283.A OE1 no hydrogen 3.512 N/A GLY 259.A N GLU 261.A O no hydrogen 2.923 N/A LYS 260.A N SER 5.A OG no hydrogen 2.972 N/A LYS 260.A NZ LEU 3.A O no hydrogen 2.722 N/A ALA 263.A N LEU 257.A O no hydrogen 2.870 N/A LEU 265.A N PHE 255.A O no hydrogen 2.847 N/A GLY 268.A N ALA 250.A O no hydrogen 2.880 N/A TYR 269.A N HIS 266.A O no hydrogen 3.137 N/A SER 270.A OG GLU 40.A OE1 no hydrogen 2.908 N/A CYS 271.A N LEU 248.A O no hydrogen 2.838 N/A LEU 272.A N ILE 7.A O no hydrogen 2.812 N/A VAL 273.A N ASN 246.A O no hydrogen 2.853 N/A ALA 275.A N LEU 70.A O no hydrogen 3.154 N/A SER 276.A OG GLU 69.A OE2 no hydrogen 2.677 N/A THR 277.A N PRO 274.A O no hydrogen 3.011 N/A THR 277.A OG1 SER 5.A OG no hydrogen 2.707 N/A PHE 280.A N ILE 240.A O no hydrogen 3.076 N/A THR 281.A N ARG 258.A O no hydrogen 2.851 N/A VAL 282.A N ALA 238.A O no hydrogen 2.865 N/A GLU 283.A N ILE 256.A O no hydrogen 2.860 N/A SER 284.A N GLY 236.A O no hydrogen 2.950 N/A SER 284.A OG TYR 254.A O no hydrogen 3.068 N/A GLY 287.A N VAL 234.A O no hydrogen 2.770 N/A LYS 288.A N GLU 252.A O no hydrogen 2.880 N/A LYS 288.A NZ ASP 233.A OD1 no hydrogen 3.058 N/A ILE 289.A N VAL 232.A O no hydrogen 3.022 N/A VAL 290.A N TYR 249.A O no hydrogen 2.769 N/A ARG 291.A N GLU 230.A O no hydrogen 2.799 N/A ARG 291.A NE GLU 230.A OE2 no hydrogen 2.766 N/A ARG 291.A NH1 GLU 230.A OE2 no hydrogen 3.067 N/A ILE 292.A N ILE 247.A O no hydrogen 2.765 N/A TYR 293.A N GLY 228.A O no hydrogen 2.932 N/A TYR 293.A OH GLU 223.A OE1 no hydrogen 2.827 N/A LYS 295.A N ASN 226.A O no hydrogen 2.904 N/A LYS 295.A NZ GLU 223.A OE2 no hydrogen 2.847 N/A LYS 295.A NZ THR 224.A O no hydrogen 2.643 N/A LYS 295.A NZ GLU 225.A OE2 no hydrogen 3.567 N/A